Keywords: Feedback regulation; Systems stability; Mathematical modelling; Network analysis; Drug resistance, Signal transduction, Network dynamics; MST2; Mammalian STE20-like protein kinase 2; Raf-1; v-raf-1 murine leukemia viral oncogene homolog 1; MEK; Mitogen-Ac
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FOXOs in cancer immunity: Knowns and unknowns
Keywords: 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot
The Hippo pathway in normal development and cancer
Keywords: BC; breast cancer; CRC; colorectal cancer; CSCs; cancer stem cells; EMT; epithelial-mesenchymal transition; GPCRs; G-protein-coupled receptors; HCC; hepatocellular carcinoma; LATS1; large tumor suppressor 1; LATS2; large tumor suppressor 2; MOB1A; MOB kin
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
Keywords: Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf
MicroRNAs associated with the pathogenesis of multiple sclerosis
Keywords: BBB; blood-brain barrier; BMI1; B lymphoma Mo-MLV insertion region 1 homolog; CAPS-3; caspase-3; CEBPB; CCAAT/enhancer-binding protein beta; CNS; central nervous system; EAE; experimental autoimmune encephalomyelitis; GA; Glatiramer acetate; HIF-1; hypo
MST2 phosphorylation at serine 385 in mitosis inhibits its tumor suppressing activity
Keywords: CDK1; cyclin-dependent kinase 1; LATS1/2; large tumor suppressor 1/2; MST1/2; mammalian sterile 20-like kinase 1/2; PLK1; polo-like kinase 1; TAZ; transcriptional co-activator with PDZ binding domain; YAP; yes-associated protein; MST2; Mitotic phosphoryla
miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells
Keywords: VSMC; Proliferation; miR-155; MST2; Inflammation; Oxidative stress;
Structure of MST2 SARAH domain provides insights into its interaction with RAPL
Keywords: MST2; RAPL/RASSF5/NORE1; SARAH domain; Coiled coil; Apoptosis;
A conserved serine residue regulates the stability of Drosophila Salvador and human WW domain-containing adaptor 45 through proteasomal degradation
Keywords: Sav; Salvador; Hpo; Hippo; Wts; Warts; Mats; Mob as tumor suppressor; WW45; WWdomain-containing adaptor 45; Mst2; mammalian sterile20-like kinase-2; Salvador; Stability; Proteasome; Hippo; WW domain-containing adaptor 45;