Keywords: Fish; Stress response; Inflammation; Cadmium pollution; Heat stress; Nrf2; NF-E2-related factor 2; Cu/Zn-SOD; copper/zinc-superoxide dismutase; CAT; catalase; HSF1; heat shock factor 1; HSF2; heat shock factor 2; HSP70; heat shock protein 70; NF-κB; nucl
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Keywords: αSMA; α-smooth muscle-actin; Cd; cadmium; ECM; extracellular matrix; ED-A FN; extra-domain-A fibronection; HFLF; human fetal lung fibroblast; MT; metallothionein; MTF-1; metal response element-binding transcription factor-1; TF; transcription factor; En
Keywords: Nrf2; NF-E2-related factor 2; Cu/Zn-SOD; copper/zinc-superoxide dismutase; CAT; catalase; HSF1; heat shock factor 1; HSF2; heat shock factor 2; HSP70; heat shock protein 70; NF-κB; nuclear transcription factor κB; IL-6; interleukin-6; IL-1β; interleuki
Keywords: Zinc; Inflammation; Liver; MTF-1; SLC39A14; SOCS3; IL-6; mice;
Keywords: AP-1; adaptor protein 1; ASL; airway surface liquid; CCO; cytochrome c oxidase; CF; cystic fibrosis; COX-2; cyclooxygenase 2; Csk; c-src kinase; DMEM; Dulbeccos' minimal essential medium; DMT1; divalent metal ion transporter 1; DUOX; dual oxidase; EGFR;
Differential effects of β-glucan on oxidative stress, inflammation and copper transport in two intestinal regions of large yellow croaker Larimichthys crocea under acute copper stress
Keywords: ATP7A; Cu-transporting ATPase A; ATP7B; Cu-transporting ATPase B; CAT; catalase; CTR1; copper transporter 1; IL-1β; interleukin-1β; IL-6; interleukin-6; iNOS; nitric oxide synthase; MTs; Metallothioneins; MTF-1; metal-responsive element-binding transcri
Synergistic cellular responses to heavy metal exposure: A minireview
Keywords: MTF-1; metal-responsive transcription factor 1; MT; metallothioneins; NF-κB; nuclear factor κB; HSR; heat shock response; Zn; zinc; Cu; copper; Fe; iron; Cd; cadmium; ROS; reactive oxygen species; TNF-α; tumor necrosis factor α; IL-6; interleukin 6; P
A fly's eye view of zinc homeostasis: Novel insights into the genetic control of zinc metabolism from Drosophila
Keywords: Drosophila; Zinc homeostasis; ZIP; ZNT; Ion transport; ER; Endoplasmic Reticulum; TPEN; N,N,Nâ²,Nâ²-tetrakis(2-pyridylmethyl)ethane-1,2-diamine; XFM; x-ray fluorescence microscopy; RNAi; RNA interference; MTF-1; metal transcription factor-1; XD; xanthin
Proteomic responses of BEAS-2B cells to nontoxic and toxic chromium: Protein indicators of cytotoxicity conversion
Keywords: SOD2; superoxide dismutase 2; ENO1; Enolase 1; UBC; polyubiquitin; GSK3β; glycogen synthase kinase 3β; TNF-α; tissue necrotic factor alpha; MTF-1; metal regulatory transcription factor 1; PSMA2; proteasome α2; PSME1; proteasome activator subunit 1; LD
Indomethacin preconditioning induces ischemic tolerance by modifying zinc availability in the brain
Keywords: CNS; central nervous system; COX; cyclooxygenase; ECA; external carotid artery; Hif-1α; hypoxia-inducing factor-1α; Hsp70; heat shock protein 70; ICA; internal carotid artery; MCAO; middle cerebral artery occlusion; MT-1/2; metallothionein-1/2; MTF-1; m
Inhibition of endogenous MTF-1 signaling in zebrafish embryos identifies novel roles for MTF-1 in development
Keywords: MTF-1; Zebrafish; Zinc homeostasis; Metal; Embryonic development;
Characterization of the GufA subfamily member SLC39A11/Zip11 as a zinc transporter
Keywords: Zinc transporter; SLC39A11/ZIP11; ZIP family; MRE; MTF-1; Zinc homeostasis
Bis(l-cysteinato)zincate(lI) as a coordination compound that induces metallothionein gene transcription without inducing cell-stress-related gene transcription
Keywords: Zn coordination compound; Metallothionein; MTF-1; Cell-stress; Transcription
A conserved cysteine cluster, essential for transcriptional activity, mediates homodimerization of human metal-responsive transcription factor-1 (MTF-1)
Keywords: EDC; 1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride; MRE; metal response element; MTF-1; metal-responsive transcription factor-1; TCEP; tris(2-carboxyethyl)phosphine; TPEN; Tetrakis(2-pyridylmethyl)ethylenediamine; VSV; vesicular stomatitis v
The taste of heavy metals: Gene regulation by MTF-1
Keywords: MTF-1; Heavy metal homeostasis; Zinc; Copper; Metallothionein; Transcription
Efficient metal-specific transcription activation by Drosophila MTF-1 requires conserved cysteine residues in the carboxy-terminal domain
Keywords: MTF-1; Transcription; Coactivator; Metal; Conformation; Metallothionein
The toxicity redox mechanisms of cadmium alone or together with copper and zinc homeostasis alteration: Its redox biomarkers
Keywords: Cadmium; Copper; Zinc; GSH; MT; Biomarkers; MTF-1; p53
Metallothionein and the biology of aging
Keywords: Caloric restriction; Diet; GH; IGF-1; Longevity; MTF-1
Metal transcription factor-1 regulation via MREs in the transcribed regions of selenoprotein H and other metal-responsive genes
Keywords: MRE, metal responsive element; MTF-1, metal element binding transcription factor 1; TrSS, translation start site; TSS, transcription start siteSelenoprotein H; MTF-1; MREs
Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity
Keywords: MTF-1; Metallothionein; Heavy metal; Oxidative stress; Reactive oxygen; Aging; Life-span; Motorneuron; Nervous system
Identification of a splice variant of the metal-responsive transcription factor MTF-1 in common carp
Keywords: Alternative spicing; Arsenic; Cadmium; Metallothionein; mtf-1;
Differential quantitative zinc-induced expression of human metallothionein isogenes in haematopoietic precursor cell lines
Keywords: DMSO; dimethyl sulfoxide; FCS; foetal calf serum; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IL-3; interleukin-3; IHC; immunohistochemical staining; MT; metallothionein; MTF-1; metal-responsive transcription factor-1; PMA; phorbol-12 myristate-13 ac
Identification and characterization of two mtf-1 genes in common carp
Keywords: Brain; Cadmium; Cold shock; Isoforms; Metallothionein; MTF-1; Stress
The influence of metallothionein on exposure to metals: An in vitro study on cellular models
Keywords: Cu; copper; GSH; glutathione; Fe; iron; MT; metallothionein; ROS; species oxygen reactive; Zn; zinc; DMT1; divalent metal transport 1; MTF-1; metal transcription factor-1; MREs; metal response elements; Accumulation; Glutathione; Metal interaction; Metall
Metallothioneins I and II: Neuroprotective significance during CNS pathology
Keywords: MTF-1; metal transcription factor-1; OH; hydroxyl radical; NO; nitric oxide; Zn2+; zinc (divalent); MRE; metal response element; PO4; phosphate group; Metallothionein; Neurodegenerative diseases; Oxidative stress; Neuronal injury;
Mtf-1 lymphoma-susceptibility locus affects retention of large thymocytes with high ROS levels in mice after γ-irradiation
Keywords: Lymphoma susceptibility; Clonal proliferation; ROS; γ-Irradiation; Mtf-1;
Understanding the mechanisms of zinc-sensing by metal-response element binding transcription factor-1 (MTF-1)
Keywords: MTF-1; Zinc; Metlloregulation; Zinc fingers; Transcription; Zinc-sensing
Cross talk of heat shock and heavy metal regulatory pathways
Keywords: Heavy metal; Cadmium; Zinc; Metallothionein; Heat shock protein 70; MTF-1; HSF1; Transcriptional repression; Protein–protein interaction
Copper homeostasis in eukaryotes: Teetering on a tightrope
Keywords: Copper scarcity; Copper importers; Ctr1B; Copper load; Metallothioneins; Copper detoxification; MTF-1
The metal-responsive transcription factor-1 contributes to HIF-1 activation during hypoxic stress
Keywords: MTF-1; HIF-1α; Hypoxia; GLUT1; Glutathione; Glutamate cysteine ligase catalytic subunit;
Quantitative PCR analysis of two molluscan metallothionein genes unveils differential expression and regulation
Keywords: AP-1; activator protein-1; bp; base pair; CDS; coding sequence; Ct; threshold cycle; EDTA; ethylenediamine tetraacetic acid; gsp; gene specific primer; M-MuLV H- RT; point mutated RNAse H (minus) Moloney Murine Leukemia Virus reverse transcriptase; MRE; m
The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen
Keywords: AEC; aortic endothelial cell; bFGF; basic fibroblast growth factor; cAMP; cyclic adenosine 3â²,5â²-monophosphate; CKI; cyclin-dependent kinase inhibitor; CRY1; cryptochrome 1; CYP3A6; cytochrome p450 oxidase 3A6; DEC1; deleted in esophageal cancer 1; 4E
Brain, aging and neurodegeneration: Role of zinc ion availability
Keywords: [Ca++]i; intracellular Ca++ concentration; [Zn++]b; zinc concentration in the blood; [Zn++]e; extracellular free zinc ion concentration; [Zn++]i; intracellular free zinc ion concentration; [Zn++]s; synaptic zinc; Aβ; amyloid beta-peptide; AD; Alzheimer d