Keywords: دوقلوهای قهوه ای 2; ABC; ATP-binding cassette; AKT; V-Akt murine thymoma viral oncogene homolog; ALDH1; aldehyde dehydrogenase 1; AR; androgen receptor; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist killer; Bax; Bcl-2-associated X protein; Bcl-2; B-c
مقالات ISI دوقلوهای قهوه ای 2 (ترجمه نشده)
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Keywords: دوقلوهای قهوه ای 2; ACC; acetyl-CoA carboxylase; ALDOA; aldolase A; AIs; aromatase inhibitors; AMPK; AMP-activated protein kinase; BC; breast cancer; CML; chronic myelogenous leukemia; CT; computed tomography; CPT1; carnitine palmitoyltransferase 1; CRC; colorectal cancer; 2
Keywords: دوقلوهای قهوه ای 2; Cordycepin; Thymic stromal lymphopoietin; Interleukin-13; Signal transducer and activator of transcription 6; Murine double minute 2;
Keywords: دوقلوهای قهوه ای 2; AFP; Alpha-fetoprotein; ANAs; Antinuclear antibodies; APCs; Antigen presenting cells; ANXA-1; Annexin A1; BRCA; Breast cancer susceptibility gene; CT; Cancer-testis; EGFR; Epidermal growth factor receptor; ELISA; Enzyme linked immunosorbent assay; HDR; Ho
Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases
Keywords: دوقلوهای قهوه ای 2; ALS; amyotrophiclateral sclerosis; AP-1; activator protein 1; APC; antigen-presenting cell; APC/C; anaphase promoting complex/cyclosome; CLR; C-type lectin receptor; CRL; Cullin RING ligase; ERK; extracellular signalregulated kinase; FANC; Fanconi anemia
Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3
Keywords: دوقلوهای قهوه ای 2; Schisandrin B; STAT3; Apoptosis; Triple negative breast cancer; Bax; Bcl-2 associated protein x; Bcl-2; B-cell lymphoma 2; Bcl-xl; B-cell lymphoma-extra large; CDC2; cell division cycle 2; DAPI; 4, 6diamidino-2-phenylindole; DMSO; dimethylsulfoxide; FITC;
MicroRNA regulation of MDM2-p53 loop in pterygium
Keywords: دوقلوهای قهوه ای 2; Pterygium; microRNA; miR-145; MDM2-p53 loop; miR-145; MicroRNA-145; CK12; Cytokeratin 12; CX43; Connexin 43; EMT; Epithelial-mesenchymal transition; GFP; Green fluorescence protein; LPC; Limbo-peripheral cornea; MDM2; Murine double minute 2; Pt; Pterygium
Thyroid hormone induce a p53-dependent DNA damage through PI3K/Akt activation in sperm
Keywords: دوقلوهای قهوه ای 2; TH; thyroid hormone; PI3K; Phosphatidyl Inositol 3-kinase; MDM2; Murine Double Minute 2; TR; thyroxine receptor; TUNEL; terminal deoxynucleotidyl transferase dUTP nick-end labelling; MMP; mitochondrial membrane potential; Sperm motility; DNA damage; l-Thy
Ameliorative effect of atractylenolide III in the mast cell proliferation induced by TSLP
Keywords: دوقلوهای قهوه ای 2; Atractylenolide III; Mast cell; Thymic stromal lymphopoietin; Murine double minute 2; Signal transducer and activator of transcription 6; Interleukin-13;
Targeting Oct2 and P53: Formononetin prevents cisplatin-induced acute kidney injury
Keywords: دوقلوهای قهوه ای 2; Cisplatin; Regeneration; Apoptosis; Oct2; p53; AKI; acute kidney injury; MDM2; murine double minute 2; Oct2; organic cation transporter 2; Mrp2; multidrug resistance-associated protein 2; BrdU; 5-bromo-2-deoxyuridine;
Polymorphisms of miR-196a2 (rs11614913) and miR-605 (rs2043556) confer susceptibility to gastric cancer
Keywords: دوقلوهای قهوه ای 2; ANXA1; annexin A1; C; control group; CI; confidence interval; EGF; epidermal growth factor; ESCC; esophageal squamous cell carcinoma; GC; gastric cancer; HER2 (c-erbB2); erb-b2 receptor tyrosine kinase 2; LFS; Li-Fraumeni syndrome; Mdm2; murine double min
Inhibition of MDM2 expression by rosmarinic acid in TSLP-stimulated mast cell
Keywords: دوقلوهای قهوه ای 2; Rosmarinic acid; Thymic stromal lymphopoietin; Murine double minute 2; Signal transducer and activator of transcription 6; Interleukin-13;
Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes
Keywords: دوقلوهای قهوه ای 2; PUVA; 8-methoxypsoralen plus UVA; RIG-1; retinoic acid induced gene 1; MDA5; melanoma differentiation associated gene 5; MAVS; mitochondrial antiviral signaling protein; TBK; TANK-binding kinase 1; IKKε; inhibitor of kappaB kinase epsilon; IRF3; interfer
Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer
Keywords: دوقلوهای قهوه ای 2; 4E-BP-1; eukaryotic initiation factor 4E binding protein-1; ATF4; activating transcription factor 4; Bcl2; B-cell lymphoma 2; C/EBP; CAAT/enhancer binding protein; cdc-2; cyclin-dependent kinase 1 (cell division cycle protein 2); CHOP; CAAT/enhancer bindi
Acteoside attenuates TSLP-induced mast cell proliferation via down-regulating MDM2
Keywords: دوقلوهای قهوه ای 2; Acteoside; Murine double minute 2; p53; Signal transducer and activator of transcription 6; Interleukin-13; Caspase-3
Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus
Keywords: دوقلوهای قهوه ای 2; PcG; polycomb group; EZH2; enhancer of zeste homolog 2; shRNA; short hairpin RNA; Rb; retinoblastoma; MDM2; murine double minute 2; CDKIs; cyclin-dependent kinase inhibitors; PRC1; polycomb repressive complex 1; PRC2; polycomb repressive complex 2; H3K27m
PI3K/Akt signaling in osteosarcoma
Keywords: دوقلوهای قهوه ای 2; OS; osteosarcoma; PI3K; phosphatidylinositol 3-kinase; PTEN; phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; RTKs; receptor tyrosine kinases; PDGFR; platelet-derived growth factor receptor; IGF1R; insulin-like growth factor 1 receptor
Hypoxia induced E-cadherin involving regulators of Hippo pathway due to HIF-1α stabilization/nuclear translocation in bone metastasis from breast carcinoma
Keywords: دوقلوهای قهوه ای 2; EMT; epithelial-mesenchymal transition; MET; mesenchymal-epithelial transition; HIF-1; hypoxia inducible factor-1; TAZ; transcriptional co-activator with PDZ-binding motif; YAP; Yes-associated protein; Wwox; WW-domain containing oxidoreductase; MDM2;
Opportunities for translation: Targeting DNA repair pathways in pancreatic cancer
Keywords: دوقلوهای قهوه ای 2; ATR; ATM-Rad3-related; BER; base excision repair; Chk1; checkpoint kinase 1; DDR; DNA damage response and repair; DNA-PKcs; DNA-PK catalytic subunit; DOT1L; DOT1-like; DSB; double strand break; FOLFIRINOX; folinic acid, 5-FU, irinotecan, oxaliplatin; 5-FU
The role of ubiquitin ligases in cardiac disease
Keywords: دوقلوهای قهوه ای 2; AChRs; acetylcholine receptors; AKAP121; A-kinase anchor protein 121; c-Cbl; Casitas b-lineage lymphoma; Cav3; cavelin 3; CHIP; c-terminus of Hsp70-interacting protein; cIAP; cellular inhibitor of apoptosis; cMyBP-C; cardiac myosin binding protein C; Drp1
Original ResearchFull Report: Basic and Translational-Alimentary TractTRIM59 Is Up-regulated in Gastric Tumors, Promoting Ubiquitination and Degradation of p53
Keywords: دوقلوهای قهوه ای 2; Oncogene; Stomach Cancer; Tumor Formation; Progression; MDM2; murine double minute 2; mRNA; messenger RNA; q-PCR; quantitative polymerase chain reaction; shRNA; short hairpin RNA; TRIM; tripartite motif;
Acidosis blocks CCAAT/enhancer-binding protein homologous protein (CHOP)- and c-Jun-mediated induction of p53-upregulated mediator of apoptosis (PUMA) during amino acid starvation
Keywords: دوقلوهای قهوه ای 2; AAR; amino acid response; Apaf-1; apoptotic protease-activating factor-1; ATF; activating transcription factor; Bcl-2; B cell lymphoma-2; Bax; Bcl-2-associated X protein; Bim; Bcl-2-interacting mediator of cell death; CHOP; CCAAT/enhancer-binding protein
Anti-HER3 Domain 1 and 3 Antibodies Reduce Tumor Growth by Hindering HER2/HER3 Dimerization and AKT-Induced MDM2, XIAP, and FoxO1 Phosphorylation
Keywords: دوقلوهای قهوه ای 2; Ab; antibody; NRG; neuregulin; PBS; phosphate-buffered saline; TR-FRET; time-resolved fluorescence resonance energy transfer; XIAP; X-linked inhibitor of apoptosis; FoxO1; forkhead box O1; MDM2; murine double minute 2; GSK3; glycogen synthase kinase 3;
Stress-Induced Isoforms of MDM2 and MDM4 Correlate with High-Grade Disease and an Altered Splicing Network in Pediatric Rhabdomyosarcoma
Keywords: دوقلوهای قهوه ای 2; COG; Children's Oncology Group; MDM2; murine double minute 2; MDM4; murine double minute 4; RMS; rhabdomyosarcoma; STS; soft tissue sarcoma;
GLTSCR2 contributes to the death resistance and invasiveness of hypoxia-selected cancer cells
Keywords: دوقلوهای قهوه ای 2; ARF; alternative reading frame; GLTSCR2; glioblastoma tumor suppressive candidate region gene 2; JNK; c-jun N-terminal kinase; MDM2; murine double minute 2; NPM; nucleophosmin; Pict-1; Protein interacting with C-terminus-1; PTEN; phosphatase and tensin ho
A clinical, pathologic, and molecular study of p53 and murine double minute 2 in penile carcinogenesis and its relation to prognosis
Keywords: دوقلوهای قهوه ای 2; Murine double minute 2; p53; Penile cancer; Molecular pathogenesis; Prognosis
Comparison of the antitumor effects of an MDM2 inhibitor, nutlin-3, in feline lymphoma cell lines with or without p53 mutation
Keywords: دوقلوهای قهوه ای 2; Cat; TP53; Murine double minute 2; Small molecule inhibitor
Mechanisms involved in alternariol-induced cell cycle arrest
Keywords: دوقلوهای قهوه ای 2; H2DFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; JC-1; 5â²,6,6â²-tetrachloro-1,1â²,3,3â²-tetraethylbenzimidazolylcarbocyanineiodide; 7-ADD; 7-amino actinomycin; 8-oxoGua; 8-oxo-7,8-dihydroguanine; AOH; alternariol; AME; alternariol monomethyl e
Back to your heart: Ubiquitin proteasome system-regulated signal transduction
Keywords: دوقلوهای قهوه ای 2; AF1/2; activation function 1/2 domains; AP-1; activator protein 1; AKT; protein kinase B; ARF-BP1; ARF binding protein 1; ATM; ataxia telangiectasia mutated; CARP1/2; caspase associated ring protein 1/2; CBP; CREB binding protein; CHIP; C-terminus of HSC7
The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53
Keywords: دوقلوهای قهوه ای 2; ASPP; Apoptosis Stimulating Protein of p53; Bax; Bcl-2-associated X protein; mdm2; murine double minute 2; PET; paired-end diTag; PIG3; p53-inducible gene 3; p53; Apoptosis Stimulating Protein of p53; p300; Apoptosis; Acetylation;
Targeting of p53 and its homolog p73 by protoporphyrin IX
Keywords: دوقلوهای قهوه ای 2; aa; amino acid; 5-ALA; 5-aminolevulinic acid; FP; fluorescence polarisation; HSA; human serum albumin; MDM2; murine double minute 2; N; NH2-terminal; dN; delta N-terminal; PAGE; polyacrylamide gel electrophoresis; PDT; photodynamic therapy; RITA; reactiva
Suppression of hypoxia inducible factor-1α (HIF-1α) by YC-1 is dependent on murine double minute 2 (Mdm2)
Keywords: دوقلوهای قهوه ای 2; Hypoxia inducible factor-1α; YC-1; Murine double minute 2; Hepatocellular carcinoma
Lung Cancer Pathogenesis Associated With Wood Smoke Exposure
Keywords: دوقلوهای قهوه ای 2; COPD; lung cancer; murine double minute 2; p53; wood smoke; BaP; benzo[a]pyrene; DU; densitometry unit; LCT; lung cancer associated with tobacco; LCW; lung cancer associated with wood smoke; MDM2; murine double minute 2; NNK; 4-(methylnitrosamino)-1-(3-py
Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis
Keywords: دوقلوهای قهوه ای 2; Aa; amino acid; CM; Complete medium; CMV; Cytolomegavirus; CRE; cyclic AMP response element; DTT; dithiothreitol; E1A and E1B; Adenovirus 5 early region 1A and 1B; FCS; Fetal calf serum; GFP; Green fluorescent protein; HDAC3; Histone deacetylase complex 3
When hypoxia signalling meets the ubiquitin-proteasomal pathway, new targets for cancer therapy
Keywords: دوقلوهای قهوه ای 2; ARD1; arrest defective-1 protein; ARNT; aryl hydrocarbon receptor nuclear translocator; bHLH; basic helix loop helix; CBP; CREB binding protein; CPT; camptothecin; C-TAD; C-terminal transactivation domain; FIH-1; factor inhibiting HIF-1; HAT; histone acet