دانلود مقالات ISI درباره N، N-دییزوپروپیلتیلامین + ترجمه فارسی

Structure-activity relationship study of tetrapeptide inhibitors of the Vascular Endothelial Growth Factor A binding to Neuropilin-1

Keywords: N، N-دییزوپروپیلتیلامین; ABTS; 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt; ACN; acetonitrile; BSA; bovine serum albumin; Dab; L-2,4-diaminobutyric acid; Dap; L-2,3-diaminopropionic acid; DIPEA; N,N-diisopropylethylamine; EC; endothelial cells; ELISA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Coating lanthanide nanoparticles with carbohydrate ligands elicits affinity for HeLa and RAW264.7 cells, enhancing their photodamaging effect

Keywords: N، N-دییزوپروپیلتیلامین; DIC; 1,3-diisopropylcarbodiimide; DIPEA; N,N-diisopropylethylamine; DLS; dynamic light scattering; DMAP; N,N-dimethyl-4-aminopyridine; DMF; N,N-dimethylformamide; DMEM; Dulbecco's Modified Eagle Medium; EPR effect; enhanced permeability and retention ef

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Calcium phosphate-polymer hybrid nanoparticles for enhanced triple negative breast cancer treatment via co-delivery of paclitaxel and miR-221/222 inhibitors

Keywords: N، N-دییزوپروپیلتیلامین; miR; micro RNA; miRi; micro RNA inhibitor; pac; paclitaxel; ER; estrogen receptor; PR; progesterone receptor; HER2/neu; epidermal growth factor receptor 2; TNBC; triple-negative breast cancer; PLGA; poly(d,l-lactide-co-glycolide); PEG; poly(ethylene-glyco

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Comparison of extracellular Cys/Trp motif between Schizosaccharomyces pombe Ctr4 and Ctr5

Keywords: N، N-دییزوپروپیلتیلامین; Ctr; copper transporter; BCA; bicinchoninic acid; Fmoc; 9-fluorenylmethyloxycarbonyl; NMP; N-methylpyrrolidone; HBTU; 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate; HOBt; 1-hydroxybenzotriazol; DIEA; N,N-diisopropylethylamine; DM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperMacrocyclization of a potent PACE4 inhibitor: Benefits and limitations

Keywords: N، N-دییزوپروپیلتیلامین; γAbu; 4-aminobutyric acid; Amba; 4-amidinobenzylamide; AMC; 7-amino-4-methylcoumarin; ATCC; American Type Culture Collection; 6-Cl-HOBt; 1-hydroxy-6-chloro-benzotriazole; DCM; dichloromethane; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Structure and activity of contryphan-Vc2: Importance of the d-amino acid residue

Keywords: N، N-دییزوپروپیلتیلامین; Conotoxin; Contryphan-Vc2; Nuclear magnetic resonance; Solution structure; Molecular dynamics; d-amino acid; BMRB; Biological Magnetic Resonance Data Bank; BSA; bovine serum albumin; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; DPC; dodec

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents

Keywords: N، N-دییزوپروپیلتیلامین; Ac; acetyl; ADME; absorption, distribution, metabolism, and excretion; aq.; aqueous; AUC; total area under the blood concentration-time curve; bid; bis in die (twice per day); Boc; (tert-butoxy)carbonyl; Bu; butyl; Bz; benzoyl; cLogP; calculate logarith

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and biological activity of cyclolinopeptide A analogues modified with γ4-bis(homo-phenylalanine)

Keywords: N، N-دییزوپروپیلتیلامین; Boc; tert-Butoxycarbonyl; C8; octyl stationary phase; C18; octadecyl stationary phase; CLA; cyclolinopeptide A; COSY-DQF; double quantum filtered proton spin correlation; CsA; cyclosporine A; DIPEA; N,N-diisopropylethylamine; DMF; dimethylformamide; DMSO;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Design and optimization of purine derivatives as in vivo active PDE10A inhibitors

Keywords: N، N-دییزوپروپیلتیلامین; DIEA; N,N-diisopropylethylamine; DME; dimethoxyethane; DMF; N,N-dimethylformamide; EDC; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; HOBt; 1-hydroxybenzotriazole; rt; room temperature; TEA; triethylamine; THF; tetrahydrofuran; Phosphodiesterase; PDE10A;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Structure-activity relationship study of a small cyclic peptide H-c[Lys-Pro-Glu]-Arg-OH: a potent inhibitor of Vascular Endothelial Growth Factor interaction with Neuropilin-1

Keywords: N، N-دییزوپروپیلتیلامین; ABTS; 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt; ACN; acetonitrile; BSA; bovine serum albumin; (bt)-VEGF165; biotinylated-VEGF165; 6-Cl-HOBt; 6-chloro-1-hydroxybenzotriazole dihydrate; DIPEA; N,N-diisopropylethylamine; DMEM;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Bivalent SIRT1 inhibitors

Keywords: N، N-دییزوپروپیلتیلامین; β-NAD+; β-nicotinamide adenine dinucleotide; NAM; nicotinamide; 2′-O-AADPR; 2′-O-acyl-ADP-ribose; RP-HPLC; reversed-phase high performance liquid chromatography; HRMS; high-resolution mass spectrometry; EDC-MeI; 1-(3-dimethylaminopropyl)-3-ethylcarb

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Anorexigenic effects induced by RVD-hemopressin(α) administration

Keywords: N، N-دییزوپروپیلتیلامین; ACN; acetonitrile; AgRP; agouti related peptide; ARC; arcuate nucleus; BAT; brown adipose tissue; CART; cocaine and amphetamine-regulated transcript; CRH; corticotrophin releasing hormone; DA; dopamine; DCM; dichloromethane; DIPEA; N,N-Diisopropylethylami

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and pharmacological evaluation of 4-hydroxyphenylglycine and 4-hydroxyphenylglycinol derivatives as GPR88 agonists

Keywords: N، N-دییزوپروپیلتیلامین; 2-PCCA; (1R,2R)-2-(pyridin-2-yl)cyclopropane carboxylic acid ((2S,3S)-2-amino-3-methylpentyl)-(4′-propylbiphenyl-4-yl)amide; 2-AMPP; (2S)-N-((1R)-2-amino-1-(4-(2-methyl-pentyloxy)phenyl)ethyl)-2-phenylpropanamide; SAR; structure activity relationship; P

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Comparative preclinical evaluation of 68Ga-NODAGA and 68Ga-HBED-CC conjugated procainamide in melanoma imaging

Keywords: N، N-دییزوپروپیلتیلامین; BFC; bifunctional chelator; DIPEA; N,N-diisopropylethylamine; EDAC; N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride; HBED-CC; N,N′-bis-[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N′-diacetic acid; MeCN; acetonitrile; MRI; magnet

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and in vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes

Keywords: N، N-دییزوپروپیلتیلامین; Quinoline; Fluorination; Phosphodiesterase 5; Radiotracer; Positron emission tomography; AD; alzheimer's disease; AllocCl; allyl chloroformate; ATR; attenuated total reflectance; cAMP; cyclic adenosine 3′,5′-monophosphate; cGMP; cyclic guanosine 3′,

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of 3,4-dihydro-2H-thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective α1D adrenoceptor antagonists

Keywords: N، N-دییزوپروپیلتیلامین; Phenoxyethylamine derivatives; Selective human α1D adrenoceptor antagonist; 3,4-Dihydro-2H-thiochromene 1,1-dioxide; Ligand-lipophilicity efficiency (LLE); AR; Adrenoceptor; BH3; borane; Boc2O; di-tert-butyl bicarbonate; t-BuXphos; 2-di-tert-butylphosp

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of amyloid fibril formation and cytotoxicity by caffeic acid-conjugated amyloid-β C-terminal peptides

Keywords: N، N-دییزوپروپیلتیلامین; Aβ; amyloid-β; AD; Alzheimer's disease; CA; caffeic acid; DCFH-DA; 2′,7′-dichlorodihydrofluorescein diacetate; DHCA; dihydrocaffeic acid; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; Gly; glycine; HBTU; O

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Design and synthesis of fused bicyclic inhibitors targeting the L5 loop site of centromere-associated protein E

Keywords: N، N-دییزوپروپیلتیلامین; DIPEA; N,N-diisopropylethylamine; HATU; hexafluorophosphate O-(7-azabenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium; PD; pharmacodynamic; CENP-E; Electrostatic potential map (EPM); 2,3-Dihydro-1-benzothiophene 1,1-dioxide derivatives; Anti-cancer agen

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and binding characteristics of [3H]neuromedin N, a NTS2 receptor ligand

Keywords: N، N-دییزوپروپیلتیلامین; BH; Bolton-Hunter; Bmax; maximal number of the binding sites; BSA; bovine serum albumin; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; EC50; half maximal effective concentration; Emax; maximal stimulation (Efficacy); GDP; guanosine 5′-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Functional evaluation of fluorescein-labeled derivatives of a peptide inhibitor of the EGF receptor dimerization

Keywords: N، N-دییزوپروپیلتیلامین; DIPEA; N,N-diisopropylethylamine; EDCI; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide; DMF; dimethylformamide; EDT; ethanedithiol; HOBt; 1-hydroxybenzotriazole; TFA; trifluoroacetic acid; TIS; triisopropylsilane; EGF; epidermal growth factor; TGF; transfo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Quantitation of total fatty acids in plasma and serum by GC-NCI-MS

Keywords: N، N-دییزوپروپیلتیلامین; ACN; acetonitrile; AMR; analytical measurement range; CI; chemical ionization; DHA; docosahexaenoic acid; DIPEA; N,N-diisopropylethylamine; DPA; docosapentaenoic acid; EFAD; essential fatty acid deficiency; EI; electron ionization; EPA; eicosapentaenoic a

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome

Keywords: N، N-دییزوپروپیلتیلامین; 20S Eukaryotic proteasome; Internally quenched peptides; Fluorescence; UPS; ubiquitin-proteasome system; ACC; 7-amino-4-carbamoylmethylcoumarin; AMC; 7-amino-4-methylocoumarin; FRET; fluorescent resonance energy transfer; ABZ; 2-aminobenzoic acid; Tyr(3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with 13C-encoded natural S1P as internal standard

Keywords: N، N-دییزوپروپیلتیلامین; 13C5-S1P; 13C5 C18-S1P; C18-S1P-ene; C18-S1P-diene; Gb3; globotriaosylceramide; lyso-Gb3; globotriaosylsphingosine; DIPEA; N,N-diisopropylethylamine; SA-1P; sphinganine-1-phosphate; S1P; sphingosine-1-phosphate; SK; sphingosine kinases; Sphingolipid; Sphi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors

Keywords: N، N-دییزوپروپیلتیلامین; AcOH; acetic acid; Ang I; angiotensin I; Ang II; angiotensin II; AUC; area under the blood concentration-time curve; C5min; concentration in plasma 5 min after administration; CLtotal; total clearance; Cmax; maximum concentration in plasma; DIEA; N,N-d

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-RafV600E and C-Raf kinase inhibitory activities

Keywords: N، N-دییزوپروپیلتیلامین; Anticancer activity; Benzothiazole; Urea; Amide; Pyridylamide; B-RafV600E; C-Raf; ATCC; American tissue culture collection; CDI; 1,1'-carbonyldiimidazole; CLogP; Calculated LogP (Partition coefficient); DIPEA; N,N-diisopropylethylamine; DTT; Dithiothreito

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma

Keywords: N، N-دییزوپروپیلتیلامین; PDK1 inhibitors; Kinase inhibitors; Oxindole derivatives; Pyridonyl derivatives; Glioblastoma; GBM stem cells; OXIDs; 2-oxindole derivatives; TBTU; N,N,N′,N′-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate; DIPEA; N,N-Diisopropylethylamine;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular interaction of δ-conopeptide EVIA with voltage-gated Na+ channels

Keywords: N، N-دییزوپروپیلتیلامین; COSY; correlation spectroscopy; DG; distance geometry; DIEA; N,N-diisopropylethylamine; Fmoc; 9-fluorenylmethoxycarbonyl; GSH; glutathione reduced; GSSG; glutathione oxidized; HBTU; O-(benzotriazol-1-yl)-N,N,N′,N′-tetramethyl-uronium-hexafluorophospha

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Development, synthesis and structure-activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei

Keywords: N، N-دییزوپروپیلتیلامین; Mip; macrophage infectivity potentiator; PPIase; peptidyl-prolyl cis/trans isomerase; LpMip; L. pneumophila Mip; BpMip; B. pseudomallei Mip; SAR; structure-activity relationship; HSQC; Heteronuclear Single Quantum Coherence; NMM; N-methylmorpholine; DIP

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives

Keywords: N، N-دییزوپروپیلتیلامین; ACN; Acetonitrile; Boc; tert-butyloxycarbonyl; CHO; Chinese hamster ovary; DCM; Dichloromethane; DIPEA; N,N-Diisopropylethylamine; DALEA; [D-Ala2, Leu5] enkephalin amide; DAMGO; [D-Ala2,NMePhe4,Gly5-ol]enkephalin; Dmt; 2,6-dimethyltyrosine; DPDPE; c[D-Pen

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis and evaluation of a gonadotropin releasing hormone-based subunit vaccine in rams (Ovis aries)

Keywords: N، N-دییزوپروپیلتیلامین; AcOH; acetic acid; Ac2O; acetic anhydride; ANOVA; analysis of variance; BSA; bovine serum albumin; BW; body weight; C16; 2-amino-d,l-hexadecanoic acids; DCM; dichloromethane; DMF; dimethyl formamide; DIPEA; N,N-diisopropylethylamine; EDTA; ethylenediamine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Brassinosteroid-BODIPY conjugates: Design, synthesis, and properties

Keywords: N، N-دییزوپروپیلتیلامین; BS; brassinosteroids; BODIPY; 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; (DHQD)2AQN; hydroquinidine anthraquinone-1,4-diyl diether; EDC; 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide hydrochloride; DIPEA; N,N-diisopropylethylamine; HOBt; 1-hydroxybenzo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Scaffolded multimers of hIAPP20-29 peptide fragments fibrillate faster and lead to different fibrils compared to the free hIAPP20-29 peptide fragment

Keywords: N، N-دییزوپروپیلتیلامین; AFM; Atomic force microscopy; CD; circular dichroism; CC; Critical concentration of fibrillation; CuAAC; Cu(I)-catalyzed alkyne-azide cycloaddition; αCD; α-cyclodextrin; N3P3; cyclotriphosphazene; DIC; Diisopropylcarbodiimide; DIPEA; N,N-diisopropylet

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis of photoreactive ivermectin B1a derivatives and their actions on Haemonchus and Bombyx glutamate-gated chloride channels

Keywords: N، N-دییزوپروپیلتیلامین; AVM; avermectin; DCC; dicyclohexylcarbodiimide; DIPEA; N,N-diisopropylethylamine; DMAP; 4-(dimethylamino)pyridine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; EDC; 1-ethyl-3-(3-dimethylamino-propyl)carbodiimide; GABA; γ-aminobutyric acid; GABAC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

PEGylation of the peptide Bac7(1-35) reduces renal clearance while retaining antibacterial activity and bacterial cell penetration capacity

Keywords: N، N-دییزوپروپیلتیلامین; Antimicrobial peptide; Proline-rich; PEGylation; Antibacterial activity; Cell penetrating; Optical imaging; Boc2O; Di-t-butyl dicarbonate; Et2O; ethyl ether; CFU; colony forming unit; Cmc; S-carboxymethyl-cysteine; DIEA; N,N-Diisopropylethylamine; HCTU; 2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Lowering the pKa of a bisimidazoline lead with halogen atoms results in improved activity and selectivity against Trypanosoma brucei in vitro

Keywords: N، N-دییزوپروپیلتیلامین; pKa; Dibasic compound; T. brucei; Imidazoline; Halogen scan; BBB; blood-brain barrier; CNS; central nervous system; DIPEA; N,N-diisopropylethylamine; HAT; human African trypanosomiasis; HEK cells; human endothelial kidney cells; TFA; trifluoroacetic aci

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Novel benzidine and diaminofluorene prolinamide derivatives as potent hepatitis C virus NS5A inhibitors

Keywords: N، N-دییزوپروپیلتیلامین; HCV; NS5A inhibitor; Benzidine; Diaminofluorene; Structure-activity relationship; HCV; hepatitis C virus; Peg-IFNα; pegylated interferon α; SVR; sustained virological response; GT1a; hepatitis C virus genotype 1a, a subtype of hepatitis C virus genoty

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3

Keywords: N، N-دییزوپروپیلتیلامین; ADT; androsterone; AR; androgen receptor; Ar; aryl group; DBD; DNA binding domain; DCM; dichloromethane; DHT; dihydrotestosterone; DIPEA; N,N-diisopropylethylamine; DMF; dimethylformamide; DMSO; dimethylsulfoxide; Δ4-dione; 4-androstene-3,17-dione; EtOAc

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2015 سفارش ترجمه

Structure-based design and synthesis of covalent-reversible inhibitors to overcome drug resistance in EGFR

Keywords: N، N-دییزوپروپیلتیلامین; CRI; covalent reversible inhibitor; EDC·HCl; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; HOBt; hydroxybenzotriazole; DIPEA; N,N-diisopropylethylamine; EGFR; epidermal growth factor receptor; NOE; nuclear Overhauser effect; NSCLC; non-sma

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2015 سفارش ترجمه

The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: Highly selective cytotoxic agents

Keywords: N، N-دییزوپروپیلتیلامین; Neocryptolepine; Antiproliferative activity; Antifungal activity; Biofilm; Guanidine group; Mechanism of action; Apoptosis; Hemolytic activity; Boc; tert-butyloxycarbonyl group; BSTU; N,N′-bis-Boc-thiourea; DIPEA; N,N-diisopropylethylamine; DMF; dimethy

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2015 سفارش ترجمه

Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities

Keywords: N، N-دییزوپروپیلتیلامین; ACAT; acyl CoA:cholesterol acyltransferase; ADME; absorption, distribution, metabolism and excretion; APCI; atomospheric pressure chemical ionization; CM; chylomicron; dba; dibenzylideneacetone; CYP; cytochrome P450; DDI; drug-drug interaction; DGAT; ac

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2015 سفارش ترجمه

Design and synthesis of novel small molecule CCR2 antagonists: Evaluation of 4-aminopiperidine derivatives

Keywords: N، N-دییزوپروپیلتیلامین; AcOH; acetic acid; Boc; tert-butyloxycarbonyl; CCL2; chemokine ligand 2; CCR2; chemokine receptor 2; DCE; dichloroethane; DCM; dichloromethane; DIPEA; N,N-diisopropylethylamine; DMAP; N,N-dimethylaminopyridine; DMSO; dimethylsulfoxide; INCB3344; N-(2-(((3

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis of IB-01212 by multiple N-methylations of peptide bonds

Keywords: N، N-دییزوپروپیلتیلامین; Me2Leu; N,N-dimethylleucine; MeLeu; N-methylleucine; MePhe; N-methylphenylalanine; MSNT; 1-(mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole; NMI; 1-methylimidazole; DIEA; N,N-diisopropylethylamine; Cbz; benzyloxycarbonyl; Depsipeptide; Macrolactonization; N

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Synthetically modified l-histidine-rich peptidomimetics exhibit potent activity against Cryptococcus neoformans

Keywords: N، N-دییزوپروپیلتیلامین; AA; amino acid; Boc; tert-butoxycarbonyl; DIC; 1,3-diisopropylcarbodiimide; DIEA; N,N-diisopropylethylamine; EYPC; egg yolk l-a-phosphatidylcholine; DMF; N,N-dimethylformamide; EYPG; egg yolk l-a-phosphatidyl-dl-glycerol; TBTU; O-(benzotriazol-1-yl)-N,N,N

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

A total synthesis of a highly N-methylated cyclodepsipeptide [2S,3S-Hmp]-aureobasidin L using solid-phase methods

Keywords: N، N-دییزوپروپیلتیلامین; Aureobasidin; N-Methylated cyclodepsipeptide; Depsidipeptide; Fmoc-based solid-phase peptide synthesis; Boc; tert-butyloxycarbonyl; BTC; bis-(trichloromethyl)-carbonate; 13C NMR; carbon-13 nuclear magnetic resonance; COSY; correlation spectroscopy; DBU; 1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A site-selective, irreversible inhibitor of the DNA replication auxiliary factor proliferating cell nuclear antigen (PCNA)

Keywords: N، N-دییزوپروپیلتیلامین; APC; allophycocyanin; ATR; ataxia telangiectasia mutated and rad3-related; BCA; bicinchoninic acid; Chk1; checkpoint kinase 1; CSK buffer; cytoskeleton buffer; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; DCM; dichloromethane; DIPEA; N,N-diisopropylethylamine

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Design, synthesis, and structure-activity relationships of a series of novel N-aryl-2-phenylcyclopropanecarboxamide that are potent and orally active orexin receptor antagonists

Keywords: N، N-دییزوپروپیلتیلامین; OX1R; orexin 1 receptor; OX2R; orexin 2 receptor; THF; tetrahydrofuran; TBDPS; tert-butyldiphenylsilyl; DMF; N,N-dimethylformamide; DIAD; diisopropyl azodicarboxylate; TBAF; tetra-n-butylammonium fluoride; DMSO; dimethyl sulfoxide; TEA; triethylamine; DCM

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI

Keywords: N، N-دییزوپروپیلتیلامین; Alzheimer's disease; Amyloid; Gadolinium; DOTA; Pyridine containing TriAza (PCTA); Magnetic resonance imaging (MRI); BAT; bis-amine-bis-thiol; BTA; 2-(4-N-methylaminophenyl)benzothiazole; CA; contrast agent; CMC; critic micelle concentration; CV; cone vol

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement

Keywords: N، N-دییزوپروپیلتیلامین; ADME; absorption, distribution, metabolism, and excretion; AMLV; amphotropic murine leukemia virus; BBB; blood-brain barrier; BIF; bioisostere factor; CNS; central nervous system; DCM; dichloromethane; DiEA; diisopropylethylamine; DIPEA; N,N-diisopropyl

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2014 سفارش ترجمه

Intramolecular Diels-Alder reaction as a key step in tandem or sequential processes: a versatile tool for the synthesis of fused and bridged bicyclic or polycyclic compounds

Keywords: N، N-دییزوپروپیلتیلامین; Diels-Alder; Natural product; One-pot; Sequential; Tandem; IMDA; intramolecular Diels-Alder; IMHDA; intramolecular hetero Diels-Alder; DA; Diels-Alder; IEDDA; intramolecular inverse-electron-demand Diels-Alder; DAIB or DIB; diacetoxyiodobenzene;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2014 سفارش ترجمه

Conotoxin truncation as a post-translational modification to increase the pharmacological diversity within the milked venom of Conus magus

Keywords: N، N-دییزوپروپیلتیلامین; Conotoxins; N-terminal modification; Milked venom; Post-translational modification; α-Conotoxin; Mass spectrometry; API; Atmospheric pressure ionization; Arg(Pbf); N-alpha-9-fluorenylmethoxycarbonyl-N-g-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-l

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه