دانلود مقالات ISI درباره Nachr + ترجمه فارسی

Induction of long-term oscillations in the γ frequency band by nAChR activation in rat hippocampal CA3 area

Keywords: γ oscillation; neural network oscillation at γ frequency band; ACSF; artificial cerebrospinal fluid; AD; Alzheimer's disease; D-AP5; D-(−)-2-amino-5-phosphonopentanoic acid; DhβE; dihydro-β-erythroidine; GABA; gamma-aminobutyric acid; KA; kainate;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes

Keywords: nAChR; nicotinic acetylcholine receptor; [3H]MLA; [3H]methyllycaconitine; [3H]TCP; piperidyl-3, 4-3H(N)]-(N-(1-(2 thienyl)cyclohexyl)-3, 4-piperidine; α-BTx; α-bungarotoxin; Varenicline; 7,8,9,10-tetrahydro-6,10-methano-6H-azepino[4,5-g]quinoxaline; RT;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Brain-inspired method for solving fuzzy multi-criteria decision making problems (BIFMCDM)

Keywords: Brain informatics; Fuzzy sets theory; Multi criteria decision making; Simulation; Web intelligence; World Wide Wisdom Web (W4); PFC; prefrontal cortex; OFC; orbito-frontal cortex; vmPFC; ventromedial prefrontal cortex; dmPFC; dorsomedial prefrontal cortex

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

3,16-Bisquaternary ammonium steroid derivatives as neuromuscular blocking agents: Synthesis and biological evaluation

Keywords: Neuromuscular blocking agent; Muscle relaxant; nAChR

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Engineering α4β2 nAChRs with reduced or increased nicotine sensitivity via selective disruption of consensus sites in the M3-M4 cytoplasmic loop of the α4 subunit

Keywords: Nicotinic acetylcholine receptor; Nicotine; Two-electrode voltage clamp; Nicotine sensitivity; Phosphorylation; nachr; nicotinic acetylcholine receptor; ACh; acetylcholine; PKA; protein kinase A; PKB; protein kinase B; PKC; protein kinase C; CKII; casein

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Acute administration of nicotine into the higher order auditory Te2 cortex specifically decreases the fear-related charge of remote emotional memories

Keywords: Nicotine; Fear memory; Auditory cortex; Incentive memory; Anxiety; CS; Conditioned stimulus; GABA; γ-aminobutyric acid; nAChR; Nicotinic acetylcholine receptor; PTSD; Post-traumatic stress disorder; US; Unconditioned stimulus; VTA; Ventral tegmental area

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Subunit interfaces contribute differently to activation and allosteric modulation of neuronal nicotinic acetylcholine receptors

Keywords: Nicotinic acetylcholine receptors; Allosteric regulation; Mutagenesis site specific; Cysteine-mediating cross-linking; Interface; Oocyte; Cys-loop receptors; nAChR; nicotinic acetylcholine receptor; Mor; morantel; Oxa; oxantel; OR2; oocyte Ringer's; DTT;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Neonatal nicotine exposure increases excitatory synaptic transmission and attenuates nicotine-stimulated GABA release in the adult rat hippocampus

Keywords: Nicotine; nAChR; Development; GABA; Glutamate; Hippocampus;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Imidacloprid and thiacloprid neonicotinoids bind more favourably to cockroach than to honeybee α6 nicotinic acetylcholine receptor: Insights from computational studies

Keywords: nAChR; nicotinic acetylcholine receptor; Ac-AChBP; Aplysia californica-acetylcholine binding protein; LGICs; ligand-gated ion channels; GABA; gamma-aminobutyric acid; 5-HT3; 5-hydroxytryptamine receptor subtype 3; CHARMM; Chemistry at Harvard Molecular Me

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Nicotinic ACh receptors as therapeutic targets in CNS disorders

Keywords: α7 receptor; α4β2 receptor; nAChR; cys-loop receptor

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Motoneuron axon pathfinding errors in zebrafish: Differential effects related to concentration and timing of nicotine exposure

Keywords: hpf; hours post-fertilization; CaP; Caudal Primary; MiP; Middle Primary; PMN; primary motoneuron; SMN; secondary motoneuron; GFP; green fluorescent protein; nAChR; nicotinic acetylcholine receptor; Axonal pathfinding; Muscle degeneration; Embryonic spinal

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

α6-Containing nicotinic acetylcholine receptors in midbrain dopamine neurons are poised to govern dopamine-mediated behaviors and synaptic plasticity

Keywords: αCtxMII; α-conotoxin MII; ACh; acetylcholine; AMPA; α-amino-3-hydroxy-5-methyl-isoxazolepropionic acid; AMPAR; α-amino-3-hydroxy-5-methyl-isoxazolepropionic acid receptor; BAC; bacterial artificial chromosome; DA; dopamine; EGTA; ethylene glycol tetra

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Inflammation-induced increase in nicotinic acetylcholine receptor current in cutaneous nociceptive DRG neurons from the adult rat

Keywords: AITC; allyl isothiocyanate; ANOVA; analysis of variance; Cap; capsaicin; CFA; complete Freund's adjuvant; DiI; 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; DMSO; dimethyl sulfoxide; DRG; dorsal root ganglion; EGTA; ethylene

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Flupyradifurone (Sivanto™) and its novel butenolide pharmacophore: Structural considerations

Keywords: ACh; acetylcholine; BgTx; bungarotoxin; CNS; central nervous system; DFT; density functional theory; FPF; flupyradifurone; IMD; imidacloprid; IRM; insect resistance management; IRAC; Insecticide Resistance Action Committee; nAChR; nicotinic acetylcholine

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2015 سفارش ترجمه

Fibroblast heterogeneity and its implications for engineering organotypic skin models in vitro

Keywords: Organotypic skin; Fibroblast heterogeneity; Wound healing; Skin models; Skin substitutes; Tissue engineering; 3D; three-dimensional; AdSCs; adipose-derived stem cells; AP-1; activated protein-1; Blimp1; B lymphocyte-induced maturation protein-1; BP; bullo

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

α7 Nicotinic acetylcholine receptor-specific antibody stimulates interleukin-6 production in human astrocytes through p38-dependent pathway

Keywords: nAChR; nicotinic acetylcholine receptor; IL-6; interleukine-6; scFv; single-chain antibody; LPS; lipopolysaccharide; GFP; green fluorescent protein; α7 Nicotinic acetylcholine receptor; Antibodies; scFv antibodies; Interleukin-6; Astrocytes; Inflammation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondria express several nicotinic acetylcholine receptor subtypes to control various pathways of apoptosis induction

Keywords: ACh; acetylcholine; nAChR; nicotinic acetylcholine receptor; cyt c; cytochrome c; DhβE; dihydro-β-erythroidine; MLA; methyllycaconitine; MPTP; mitochondria permeability transition pore; CaMKII; calcium-calmodulin-dependent kinase; PI3K; phosphatidylinos

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Probing the non-canonical interface for agonist interaction with an α5 containing nicotinic acetylcholine receptor

Keywords: Addiction; Biophysics; Cholinergic receptor; Electrophysiology; Ion channels; Nicotinic acetylcholine receptors; nAChR; nicotinic acetylcholine receptor; CNS; central nervous system; nH; Hill coefficient; A2B3; high sensitivity (α4β2)2(β2) receptor; A3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Suppression of inflammatory events associated to intestinal ischemia-reperfusion by 5-HT1A blockade in mice

Keywords: I/R; ischemia-reperfusion; 5-HT; 5-hydroxytryptamine; IPC; ischemic preconditioning; SERT; serotonin re-uptake transporter; nAchR; nicotinic receptor; MLA; methyllycaconitine; SMA; superior mesenteric artery; MPO; myeloperoxidase; MDA; malondialdehyde;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Concomitant alpha7 and beta2 nicotinic AChR subunit deficiency leads to impaired energy homeostasis and increased physical activity in mice

Keywords: nAChR; Islet; Adipocyte; Obesity; Diabetes;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacological chaperoning of nAChRs: A therapeutic target for Parkinson's disease

Keywords: Pharmacological chaperone; Chaperoning; Nicotine; nAChR; Tobacco; Neuroprotection; Parkinson's disease; Neurodegeneration; Unfolded protein response; Dopaminergic; Endoplasmic reticulum stress; FRET; TIRF; Confocal; ER exit sites; Golgi; Ligand; COPII; CO

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Contribution of α4β2 nAChR in nicotine-induced intracellular calcium response and excitability of MSDB neurons

Keywords: Nicotine; nAChR; MSDB; Calcium image; DhβE; MLA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

A signal peptide missense mutation associated with nicotine dependence alters α2*-nicotinic acetylcholine receptor function

Keywords: Nicotinic acetylcholine receptor; Signal peptide; Single nucleotide polymorphism; Missense mutation; Receptor structure-function; Electrophysiology; ACh; acetylcholine; nAChR; nicotinic acetylcholine receptor(s); Imax; peak current response; SNP; single n

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Biophysical and pharmacological characterization of α6-containing nicotinic acetylcholine receptors expressed in HEK293 cells

Keywords: ACh; Acetylcholine; nAChR; nicotinic acetylcholine receptor; α6⁎; α6-containing; TM; transmembrane segment; Nicotinic; Acetylcholine; Receptors; Alpha6; Beta2; Electrophysiology;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Cholinergic receptor blockade by scopolamine and mecamylamine exacerbates global cerebral ischemia induced memory dysfunction in C57BL/6J mice

Keywords: GCI/R; Global cerebral ischemia/reperfusion injury; ACh; Acetylcholine; mAChR; Muscarinic acetylcholine receptor; nAChR; Nicotinic acetylcholine receptor; AChE; Acetylcholinesterase; ChAT; Choline acetyl transferases; CA1; Cornu Ammonis area 1; BCCAo; Bil

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Nicotine mediates oxidative stress and apoptosis through cross talk between NOX1 and Bcl-2 in lung epithelial cells

Keywords: AEC; alveolar epithelial cell; Bis I; bisindolylmaleimide I; BEAS-2B; immortalized human bronchial epithelial cells; DHE; dihydroethidium; DMSO; dimethyl sulfoxide; ER; endoplasmic reticulum; GKT136901; NOX1/NOX4 dual inhibitor; mKRB; modified Krebs-Rin

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: Synthesis, pharmacological evaluation and mechanistic studies

Keywords: Alpha4Beta2 nicotinic receptor; MDMA; Enantioselective binding; Receptor up-regulation; Molecular modelling; Stereoselective synthesis; AP; alternative pose; BP; best pose; CNS; central nervous system; DA; dopamine; MD; molecular dynamics; MDMA; N-3,4-met

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: Implications for neuropsychiatric diseases

Keywords: nAChR; nicotinic acetylcholine receptor; NMDAR; N-methyl-d-aspartate receptor; SR; serine racemase; VGLUT1; vesicular glutamate transporter 1; WT; wild-type; α7-KO; α7 nAChR null; α7 nicotinic acetylcholine receptor; Synaptic NMDA receptor; Extrasynapt

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Cortical parvalbumin GABAergic deficits with α7 nicotinic acetylcholine receptor deletion: implications for schizophrenia

Keywords: nAChR; nicotinic acetylcholine receptor; PV; parvalbumin; SST; somatostatin; GAD65/67; glutamic acid decarboxylase 65/67; GABAAα1; α1 subunit of GABAA receptors; VGAT; vesicular GABA transporter; NMDAR; N-methyl-d-aspartate receptor; VGLUT1; vesicular g

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs)

Keywords: nAChR; α4β2; α6/α3β2β3; Binding; Agonism; Modeling

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Brain region specific modulation of ethanol-induced depression of GABAergic neurons in the brain reward system by the nicotine receptor antagonist mecamylamine

Keywords: Alcohol; GABA; nAChR; Reward; Nucleus accumbens; VTA;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2014 سفارش ترجمه

Planarians require an intact brain to behaviorally react to cocaine, but not to react to nicotine

Keywords: APW; artificial pond water; nAChR; nicotinic acetylcholine receptors; pSLMs; planarian seizure-like movements; planaria; nicotine; cocaine; regeneration; seizure-like behavior;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Piperidine, pyridine alkaloid inhibition of fetal movement in a day 40 pregnant goat model

Keywords: nAChR; nicotinic acetylcholine receptor; CTx; alpha conotoxin; Piperidine alkaloids; Pyridine alkaloids; Fetal movement;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

QM-polarized ligand docking accurately predicts the trend in binding affinity of a series of arylmethylene quinuclidine-like derivatives at the α4β2 and α3β4 nicotinic acetylcholine receptors (nAChRs)

Keywords: ACHBP; acetylcholine-binding protein; Ach; acetylcholine; CNS; central nervous system; MEC; minimum-effective concentration; nAChR; nicotinic acetylcholine receptor; NIC; nicotine; Pdb; protein databank; rmsd; root-mean-squared-deviation; ROC; receiver op

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacological properties and predicted binding mode of arylmethylene quinuclidine-like derivatives at the α3β4 nicotinic acetylcholine receptor (nAChR)

Keywords: ACHBP; acetylcholine-binding protein; Ach; acetylcholine; CNS; central nervous system; MEC; minimum-effective concentration; nAChR; nicotinic acetylcholine receptor; NIC; nicotine; Pdb; protein databank; rmsd; root-mean-squared-deviation; ROC; receiver op

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Importance of recognition loops B and D in the activation of human 5-HT3 receptors by 5-HT and meta-chlorophenylbiguanide

Keywords: 5-HT; mCPBG; 5-HT3A receptor; 5-HT3AB receptor; Receptor activation; 5-HT; 5-hydroxytryptamine; mCPBG; meta-chlorophenylbiguanide; 5-HT3AR; 5-hydroxytryptamine type 3A receptor; 5-HT3ABR; 5-hydroxytryptamine type 3AB receptor; nAChR; nicotinic acetylcholi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization of cys-loop receptor genes involved in inhibitory amine neurotransmission in parasitic and free living nematodes

Keywords: LGIC; ligand-gated ion channel; LGCC; ligand-gated chloride channel; nAChR; nicotinic acetylcholine receptor; cDNA; copy DNA; RT-PCR; reverse-transcription polymerase chain reaction; RACE; rapid amplification of cDNA ends; TM; transmembrane; bp; base pair

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Nitric oxide enhances increase in cytosolic Ca2+ and promotes nicotine-triggered MAPK pathway in PC12 cells

Keywords: CaM; calmodulin; CaMK; Ca2+/calmodulin-dependent protein kinase; ERK; extracellular signal-regulated kinase; MAPK; mitogen-activated protein kinase; nAChR; nicotinic acetylcholine receptor; NO; nitric oxide; nNOS; neuronal nitric oxide synthase; PKC; prot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Therapeutic effectiveness of botulinum neurotoxin A: Potent blockade of autonomic transmission by targeted cleavage of only the pertinent SNAP-25

Keywords: SNAREs; Autonomic neurons; Acetylcholine; Neurotherapeutics; ACSF; artificial cerebrospinal fluid; BoNT; botulinum neurotoxin; BoNT/A - G; BoNT type A - G; DAPI; 4′,6-diamidino-2-phenylindole; HC and HN; C- and N-terminal halves of the toxins' heavy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Conotoxin truncation as a post-translational modification to increase the pharmacological diversity within the milked venom of Conus magus

Keywords: Conotoxins; N-terminal modification; Milked venom; Post-translational modification; α-Conotoxin; Mass spectrometry; API; Atmospheric pressure ionization; Arg(Pbf); N-alpha-9-fluorenylmethoxycarbonyl-N-g-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-l

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

β-Adrenergic system, a backstage manipulator regulating tumour progression and drug target in cancer therapy

Keywords: FAK; focal adhesion kinase; PKA; protein kinase A; BAD; BCL2-associated death protein; VEGF; vascular endothelial growth factor; PlGF; placenta-derived growth factor; PDGF; platelet-derived growth factor; TGF-β; transforming growth factor β; HIF-1α; hy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Mechanisms of conotoxin inhibition of N-type (Cav2.2) calcium channels

Keywords: N-type VGCC; neuronal-type voltage-gated calcium channel; CDI; Ca2 +-dependent inactivation; GPCR; G protein-coupled receptor; GABA; γ-aminobutyric acid; GABABR; GABAB receptor; siRNA; small interfering RNA; VFT; Venus flytrap module; nAChR; nicotinic a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Angiotensin AT1 and AT2 receptor antagonists modulate nicotine-evoked [3H]dopamine and [3H]norepinephrine release

Keywords: Ang II; angiotensin II; DA; dopamine; MEC; mecamylamine; nAChR; nicotinic acetylcholine receptor; NE; norepinephrine; PD123319; 1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Interactions of acetylcholine binding site residues contributing to nicotinic acetylcholine receptor gating: Role of residues Y93, Y190, K145 and D200

Keywords: ACh; acetylcholine; nAChR; nicotinic acetylcholine receptor; AChBP; acetylcholine binding protein; LBD; ligand binding domain; dTC; d-tubocurarine; DC6C; Dansyl C6 Choline; nAChR; Resting state; Desensitized state; αγ interface; αδ interface; Molecula

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

TC-8831, a nicotinic acetylcholine receptor agonist, reduces l-DOPA-induced dyskinesia in the MPTP macaque

Keywords: Dyskinesia; Primate; MPTP; nAchR;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Novel 2-(substituted benzyl)quinuclidines inhibit human α7 and α4β2 nicotinic receptors by different mechanisms

Keywords: nAChR; nicotinic acetylcholine receptor; ACh; acetylcholine; CCh; carbamylcholine; [3H]MLA; [3H]methyllycaconitine; RT; room temperature; IC50; ligand concentration that produces 50% inhibition (of binding or of agonist activation); Ki; inhibition constan

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Identifying SNP targeted pathways in partial epilepsies with genome-wide association study data

Keywords: ADNFLE; autosomal dominant nocturnal frontal lobe epilepsy; epiGAD; Epilepsy Genetic Association Database; ECM; extracellular matrix; GWAS; genome-wide association study; KEGG; Kyoto Encyclopedia of Genes and Genomes; LD; linkage disequilibrium; MTLE; mes

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Granulocyte colony stimulating factor (GCSF) improves memory and neurobehavior in an amyloid-β induced experimental model of Alzheimer's disease

Keywords: GCSF; granulocyte colony-stimulating factor; ICV; intracerebroventricular; AD; Alzheimer's disease; Aβ1-42; amyloid-beta (1-42); DG; dentate gyrus; NMDA; N-methyl-d-aspartate; EPO; erythropoietin; BDNF; brain-derived neurotrophic factors; NBT; nitro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Point-to-point ligand-receptor interactions across the subunit interface modulate the induction and stabilization of conformational states of alpha7 nAChR by benzylidene anabaseines

Keywords: ACh; acetylcholine; nAChR; nicotinic acetylcholine receptor; BA; benzylidene anabaseine; RD; residual desensitization; Ds; PAM-sensitive desensitization; Di; PAM-insensitive desensitization; PAM; positive allosteric modulator; LBD; ligand-binding domain;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Evolution of secondary metabolites in legumes (Fabaceae)

Keywords: CG; cardiac glycoside; FC; furanocoumarin; NPAA; Non-protein amino acid; QA; Quinolizidine alkaloids; PA; Pyrrolizidine alkaloids; 5HT2 R; 5-hydroxytryptamine receptor; mAChR; muscarinic acetylcholine receptor; nAChR; nicotinic acetylcholine receptor; GAB

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه