دانلود مقالات ISI درباره Nachr + ترجمه فارسی

Attenuation of CNS inflammatory responses by nicotine involves α7 and non-α7 nicotinic receptors

Keywords: nAChR; nicotinic acetylcholine receptor; MS; multiple sclerosis; EAE; experimental autoimmune encephalomyelitis; MOG; myelin oligodendrocyte glycoprotein; Treg; regulatory T cell; MRI; magnetic resonance imaging;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2011 سفارش ترجمه

Mechanisms of imidacloprid resistance in Nilaparvata lugens by molecular modeling

Keywords: nAChR; Imidacloprid; Homology model; Docking; Resistance

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

A caged nicotine with nanosecond range kinetics and visible light sensitivity

Keywords: Caged compound; Ruthenium complex; Nicotine; Leech; Neurotransmitter; nAChR

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Afterhyperpolarization induced by the activation of nicotinic acetylcholine receptors in pelvic ganglion neurons of male rats

Keywords: ACh; acetylcholine; MPG; major pelvic ganglion; nAChR; nicotinic acetylcholine receptor; [Ca2+]i; intracellular calcium ion concentration; [Na+]i; intracellular sodium ion concentration; Nicotinic acetylcholine receptor; Autonomic ganglia; Afterhyperpolar

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Anesthetic effects on the structure and dynamics of the second transmembrane domains of nAChR α4β2

Keywords: Mechanisms of general anesthesia; Halothane; Isoflurane; Volatile anesthetics; PISEMA; Solid state NMR; nAChR; a4b2; Neuronal nAChR

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

In vitro and in vivo characterization of a novel negative allosteric modulator of neuronal nAChRs

Keywords: Neuronal nicotinic acetylcholine receptors; Negative allosteric modulator; Patch-clamp; Binding; Nicotine-induced antinociception; nAChR; nicotinic acetylcholine receptor; NAM; negative allosteric modulator; PCP; phencyclidine; HDMP; 1,2,3,3a,4,8b-hexahyd

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

NMR structure of the transmembrane domain of the n-acetylcholine receptor β2 subunit

Keywords: Nicotinic acetylcholine receptor; nAChR; NMR; HFIP; Ion channel structure; Cys-loop structure

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Repeated nicotine administration robustly increases bPiDDB inhibitory potency at α6β2-containing nicotinic receptors mediating nicotine-evoked dopamine release

Keywords: nAChR; nicotinic acetylcholine receptor; DA; dopamine; NIC; nicotine; SAL; saline; MEC; mecamylamine; DHβE; dihydro-β-erythroidine; α-CtxMII; α-conotoxin MII; bPiDDB; N,N′-dodecane-1,12-diyl-bis-3-picolinium dibromide; r-bPiDDB; 1,12-bis(3-methyl-1,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Additive and synergistic effects of fetal nicotine and dexamethasone exposure on cholinergic synaptic function in adolescence and adulthood: Implications for the adverse consequences of maternal smoking and pharmacotherapy of preterm delivery

Keywords: ACh; acetylcholine; ANOVA; analysis of variance; ChAT; choline acetyltransferase; GD; gestational day; HC3; hemicholinium-3; nAChR; nicotinic acetylcholine receptor; PN; postnatal day; Acetylcholine; Brain development; Dexamethasone; Glucocorticoids; Nico

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Docking to flexible nicotinic acetylcholine receptors: A validation study using the acetylcholine binding protein

Keywords: Protein flexibility; Molecular docking; Ensemble generation; Nicotinic; Acetylcholine receptors; nAChR; Acetylcholine binding protein; AChBP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Development of radioligands with optimized imaging properties for quantification of nicotinic acetylcholine receptors by positron emission tomography

Keywords: PET; Positron emission tomography; nAChR; Radioligand; Nicotine; Nicotinic acetylcholine receptor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Research ReportOlfactory discrimination varies in mice with different levels of α7-nicotinic acetylcholine receptor expression

Keywords: α7; α7-nicotinic acetylcholine receptor; nAChR; nicotinic acetylcholine receptor; +/+; wild type; +/−; heterozygous knock-out; −/−; homozygous knock-out; α-BTX; [125I] α-bungarotoxin; OB; olfactory bulb; HDB; horizontal limb of the diagonal band

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3)-scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system

Keywords: postsynaptic density; peripheral nervous system; motor endplate; superior cervical ganglion; myenteric ganglion; intraganglionic laminar endings; ANS; autonomic nervous system; AZ; active zone; BT; α-bungarotoxin; DAB; diaminobenzidine; ENS; enteric nerv

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors

Keywords: Nicotinic; nAChR; Acetylcholine; Receptors; α4β2; ABT-594; Diamines

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Association of N-type calcium channel autoimmunity in patients with autoimmune autonomic ganglionopathy

Keywords: nAChR; nicotinic acetylcholine receptor; AAG; autoimmune autonomic ganglionopathy; CASS; composite autonomic severity score; QSART; quantitative sudomotor axon reflex test; TST; thermoregulatory sweat test; Autonomic failure; Autoimmune ganglionopathy; Ca

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Gamma-lactams—A novel scaffold for highly potent and selective α7 nicotinic acetylcholine receptor agonists

Keywords: γ-Lactams; α7; Nicotinic; nAChR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

3D-QSAR and QSSR studies of 3,8-diazabicyclo[4.2.0]octane derivatives as neuronal nicotinic acetylcholine receptors by comparative molecular field analysis (CoMFA)

Keywords: nAChR; CoMFA; 3D-QSAR; 3D-QSSR; Subtype-selectivity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates – subtype selective, high affinity α7 nicotinic acetylcholine receptor agonists

Keywords: Alpha 7; Nicotinic acetylcholine receptor; nAChR; SAR; 1,4-Diazabicyclo[3.2.2]nonane phenyl carbamate; Agonist

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

5-(2-Pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes: Synthesis of all the stereoisomers and α4β2 nicotinic affinity

Keywords: nAChR; Nicotine; Ligand; Affinity; Oxazolidinone; Benzodioxane

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Signal intensities of radiolabeled cRNA probes used alone or in combination with non-isotopic in situ hybridization histochemistry

Keywords: Double in situ hybridization; GABAergic interneuron; GAD67; nAChR; Nicotinic; Autoradiography; Parlodion;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Treating Tobacco Dependence in Light of the 2008 US Department of Health and Human Services Clinical Practice Guideline

Keywords: CI; confidence interval; nAChR; nicotinic acetylcholine receptor; NRT; nicotine replacement therapy; OR; odds ratio; SR; sustained-release;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Acetylcholine receptor subunit genes from Ancylostoma caninum: Altered transcription patterns associated with pyrantel resistance

Keywords: Ancylostoma caninum; Pyrantel; Resistance; nAChR; Transcription

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Role of acetylcholine receptor domains in ion selectivity

Keywords: Molecular dynamics; Brownian dynamics; nAChR; Ion channel; Membrane protein; Selectivity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Combined roles of loops C and D in the interactions of a neonicotinoid insecticide imidacloprid with the α4β2 nicotinic acetylcholine receptor

Keywords: Neonicotinoids; Imidacloprid; Nicotinic acetylcholine receptor; Ion channels; Ligand binding domain; Chicken α4β2 nicotinic receptor; Homology modeling; Acetylcholine binding protein; ACh; acetylcholine; nAChR; nicotinic acetylcholine receptor; EC50; co

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels

Keywords: UTR; Untranslated region; α-BTX; α-bungarotoxin; nAChR; Nicotinic acetylcholine receptor; Nicotinic receptor; Genetics; Mice; Gene expression; Post-transcriptional;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Expression of nicotinic acetylcholine receptors and subunit messenger RNAs in the enteric nervous system of the neonatal rat

Keywords: gastrointestinal; nicotine; myenteric plexus; submucosal; in situ hybridization; epibatidine; CNS; central nervous system; ENS; enteric nervous system; fEPSP; fast excitatory postsynaptic potential; GI; gastrointestinal; nAChR; nicotinic acetylcholine rec

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of α4β2 nicotinic acetylcholine receptors (α4β2-nAChRs) in the brain with positron emission tomography

Keywords: Nicotinic acetylcholine receptor; nAChR; PET; Radioligand

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Importance of the C-terminus of the human 5-HT3A receptor subunit

Keywords: LGIC; 5-HT3A receptor 5-HT3A receptor subunit; C-terminus; Protein folding and stability; HEK; human embryonic kidney; LGIC; ligand-gated ion channel; nAChR; nicotinic acetylcholine receptor; 5-HT; 5-hydroxytryptamine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Cellular distribution of the nicotinic acetylcholine receptor α7 subunit in rat hippocampus

Keywords: ACSF; artificial cerebrospinal fluid; AHSP; acute hippocampal slice preparation; AMPAR; α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor; BGT; α-bungarotoxin; BS3; bis(sulfosuccinimidyl) suberate; BSA; bovine serum albumin; BSS; balanced sa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Clinical Perspective and Recent Development of PET Radioligands for Imaging Cerebral Nicotinic Acetylcholine Receptors

Keywords: Positron emission tomography; PET; nAChR; Nicotine; Radioligands;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Design and expression of human α7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties

Keywords: α-bgtx; α-bungarotoxin; α7-dm-ECD; double mutant of the α7-ECD; α7-wt-ECD; wild-type of the α7-ECD; ACh; acetylcholine; AChBP; acetylcholine-binding protein; BSA; bovine serum albumin; CCh; carbamylcholine; CD; circular dichroism; DLS; dynamic light

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Neuronal Ca2+ sensor VILIP-1 leads to the upregulation of functional α4β2 nicotinic acetylcholine receptors in hippocampal neurons

Keywords: ACh; acetylcholine; NCS; neuronal Ca2+ sensor; nAChR; nicotinic acetylcholine receptor, VSNL1, visinin-like protein-1.;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Chronic neonatal nicotine exposure increases mRNA expression of neurotrophic factors in the postnatal rat hippocampus

Keywords: Acetylcholine; Nicotinic; Hippocampal; Development; nAChR

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Vagus Nerve Activity Augments Intestinal Macrophage Phagocytosis via Nicotinic Acetylcholine Receptor α4β2

Keywords: ACh; acetylcholine; DHβE; dihydro-β-erythroidine; LPMF; lamina propria macrophages; nAChR; nicotinic acetylcholine receptor; PMF; primary peritoneal cells; VNS; vagus nerve stimulation;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

Target site occupancy: Emerging generalizations from clinical and preclinical studies

Keywords: Target site occupancy; Receptor reserve; Positron Emission Tomography; Single Photon Emission Computed Tomography; G protein-coupled receptor; Target biomarker; BZD; benzodiazepine; CNS; central nervous system; DAT; dopamine transporter; EEDQ; N-ethoxycar

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2009 سفارش ترجمه

Pharmacophore model for neonicotinoid insecticides

Keywords: 3D-QSAR; Pharmacophore; nAChR; Neonicotinoid insecticides

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Deconstructing cytisine: The syntheses of (±)-cyfusine and (±)-cyclopropylcyfusine, fused ring analogs of cytisine

Keywords: Cytisine; Cyfusine; Nicotinic acetylcholine receptor; [3 + 2] cycloaddition; Pyridone; Cyclopropanation; (±)-Cytisine; (±)-Cyfusine; nAChR; (α3)2(β4)3(α3)2(β4)3; (α4)2(β2)3∗

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Chronic nicotine stimulation modulates the immune response of mucosal T cells to Th1-dominant pattern via nAChR by upregulation of Th1-specific transcriptional factor

Keywords: nAChR; T cells; Inflammatory bowel disease; Ulcerative colitis; T-bet; GATA-3

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the α7 nicotinic acetylcholine receptor: In vitro and in vivo activity

Keywords: Azabicyclic; α7; Nicotinic; nAChR; Schizophrenia; PHA-543613; PHA-709829

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Neonatal nicotine exposure impairs development of auditory temporal processing

Keywords: ABR; auditory brainstem response; AC; auditory cortex; gap-PPI; gap-induced prepulse inhibition; MGB; medial geniculate body; nAChR; nicotinic acetylcholine receptors; NB-PPI; narrow band noise induced prepulse inhibition; P8; postnatal day 8; RMS; root m

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

5-Iodo-A-85380, a specific ligand for α4β2 nicotinic acetylcholine receptors, prevents glutamate neurotoxicity in rat cortical cultured neurons

Keywords: nAChR; nicotinic acetylcholine receptor; 5IA; 5-iodo-3-(2(S)-azetidinylmethoxy)pyridine; Glu; glutamate; MEC; mecamylamine; SCOP; scopolamine; DHβE; dihydro-β-erythroidine; α-BGT; α-bungarotoxin; Nicotinic acetylcholine receptor; α4β2 subtype; 5-iod

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Recurrent exposure to nicotine differentiates human bronchial epithelial cells via epidermal growth factor receptor activation

Keywords: Lung epithelial cells; Nicotine; nAChR; EGFR; NF-kB; NHBE;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Mutations in Dα1 or Dβ2 nicotinic acetylcholine receptor subunits can confer resistance to neonicotinoids in Drosophila melanogaster

Keywords: nAChR; Drosophila; Neonicotinoid; Mutagenesis; Resistance; Dα1; Dβ2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation

Keywords: nAChR; neuronal nicotinic acetylcholine receptor; α7; alpha 7; UVR; ultraviolet radiation; IL-1β; interleukin 1 beta; IL-6; interleukin 6; TNFα; tumor necrosis factor alpha; SOCS3; suppressor of cytokine signaling 3; KO; knock-out.; Neuronal nicotinic;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Quantum-chemical, NMR and X-ray diffraction studies on (±)-1-[3,4-(methylenedioxy)phenyl]-2-methylaminopropane

Keywords: MDMA; nAChR; NMR; Semi-empirical and ab initio calculations; X-ray structure

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Transgenic mice overexpressing human acetylcholinesterase and the Swedish amyloid precursor protein mutation: Effect of nicotine treatment

Keywords: Aβ; hAChE-Tg//APPswe mice; nAChRs; l(−)-nicotine; d(+)-nicotine; AChE; acetylcholinesterase; AChE-S; synaptic acetylcholinesterase; AD; Alzheimer's disease; APP; amyloid precursor protein; APPswe mice; transgenic mice carrying the Swedish mutation of

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

The nicotinic activation of the denervated sympathetic neuron of the rat

Keywords: ganglionic synaptic current; nicotinic receptors; denervation; agonist activation; permeation properties; ACh; acetylcholine; DMPP; dimethylphenylpiperazinium; EACh; equilibrium potential for diffusing acetylcholine; EDMPP; equilibrium potential for dimet

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Research ReportAdult and periadolescent rats differ in expression of nicotinic cholinergic receptor subtypes and in the response of these subtypes to chronic nicotine exposure

Keywords: A-85380; 5-iodo-3-(2(S)-azetidinylmethoxy)pyridine; α-CtxMII; α-conotoxin MII; nAChR; neuronal nicotinic acetylcholine receptor; Nicotine; Adolescence; Dependence; Nicotinic receptor subtypes; Autoradiography;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Nicotine and ethanol interact during adolescence: Effects on the central cholinergic systems

Keywords: ANOVA; analysis of variance; ChAT; choline acetyltransferase; FPLSD; Fisher's Protected Least Significant Difference; HC-3; hemicholinium-3; nAChR; nicotinic acetylcholine receptor; PN; postnatal day; rANOVA; repeated-measures analysis of variance; Adoles

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Synaptic plasticity in the basal ganglia: A similar code for physiological and pathological conditions

Keywords: 3-NP; 3-nitropropionic acid; AMPA; α-amino-3-hydroxy-5-methyl-isoxazole-4-propionate; cAMP; cyclic adenosine monophosphate; CB1; cannabinoid 1 receptor subtype; Cdk5; cyclin-dependent kinase 5; D1; dopamine D1 receptor subtype; D2; dopamine D2 receptor s

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2008 سفارش ترجمه