Keywords: Oral squamous cell carcinoma; Head and neck cancer; Tongue cancer; OPLS-DA; Tissue proteomics; CA1; S100A7; Neutrophil defensin 1; ANP32B; Immunohistochemistry; ALYREF; THO complex subunit 4; ANP32B; Acidic leucine-rich nuclear phosphoprotein 32 family me
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Keywords: AML; acute myeloid leukemia; BSA; bovine serum albumin; DPF; deferiprone (3-hydroxy-1,2-dimethyl-4-pyridinone); DFO; deferoxamine; ESA; erythropoietic stimulating agents; EDTA; ethylene-diamine tetracetate; FAC; ferric ammonium citrate; FIC; functional ir
Keywords: CMT; Charcot Marie Tooth disease; AD; Autosomal dominant; AR; Autosomal recessive; MNCV; Motor nerve conduction velocity; CMAP; Compound muscle action potential; PMP22; Peripheral myelin protein 22; HMSN; Hereditary motor sensory neuropathy; LITAF; lipopo
Keywords: ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; Bcl-2; B-cell lymphoma 2; BiP; binding immunoglobulin protein; bZIP; basic leucine zipper; CDK; cyclin-dependent kinase; CDKI; CD
A novel homozygous NDRG1 mutation in a Chinese patient with Charcot-Marie-Tooth disease 4D
Keywords: CMT4D; NDRG1; Q185X; Non-European population;
NDRG1 disruption alleviates cisplatin/sodium glycididazole-induced DNA damage response and apoptosis in ERCC1-defective lung cancer cells
Keywords: Nucleotide excision repair (NER) pathway; ERCC1; NDRG1; RNA-Seq; Drug resistance; Cisplatin; CMNa; Chemotherapy;
N-myc downstream-regulated gene 1 facilitates influenza A virus replication by suppressing canonical NF-κB signaling
Keywords: HPAI A/H5N1 virus; NDRG1; NF-κB; Innate immunity response;
HER4 promotes cell survival and chemoresistance in osteosarcoma via interaction with NDRG1
Keywords: OS; osteosarcoma; HER4; erb-b2 receptor tyrosine kinase 4; NDRG1; N-myc downstream regulated gene; SP; sphere; FBS; free bovine serum; IHC; immunohistochemistry; TMA; tissue microarray; Co-IP; co-immunoprecipitation; MTX; methotrexate; DOX; doxorubicin; H
Identification of differential phosphorylation and sub-cellular localization of the metastasis suppressor, NDRG1
Keywords: NDRG1; Dp44mT; Metastasis suppressor;
Increased NDRG1 expression attenuate trophoblast invasion through ERK/MMP-9 pathway in preeclampsia
Keywords: NDRG1; Preeclampsia; Placenta; Invasion; ERK1/2;
Original ArticleN-myc downstream regulated gene 1(NDRG1) promotes the stem-like properties of lung cancer cells through stabilized c-Myc
Keywords: NDRG1; Cancer initiating cells; Lung cancer; c-Myc; Skp2;
No changes in heme synthesis in human Friedreich´s ataxia erythroid progenitor cells
Keywords: AAS; atomicabsorption spectrophotometry; 5-ALA; 5-aminoluvulinic acid; APP; amyloid beta precursor protein; BSA; bovine serum albumin; ECLIA; electrochemiluminescence immunoassay; EPAS1; hypoxia-inducible factor 2-alpha; Epo; erythropoietin; FAS; ferrous
Hemidesmosomal linker proteins regulate cell motility, invasion and tumorigenicity in oral squamous cell carcinoma derived cells
Keywords: HD; hemidesmosome; OSCC; oral squamous cell carcinoma; NDRG1; N-myc downstream regulated gene 1; SWATH; sequential window acquisition of all theoretical fragment ion spectra; Ex/Em; extension/emission; ns; non significant; BPAG1e; Plectin; NDRG1; Cell mot
NDRG1 overexpressing gliomas are characterized by reduced tumor vascularization and resistance to antiangiogenic treatment
Keywords: Glioma angiogenesis; Antiangiogenic treatment; Resistance to antiangiogenesis; Glioma microcirculation; TNFSF15; NDRG1;
Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics
Keywords: AC; adenylyl cyclase; AI; anemia of inflammation; cdks; cyclin-dependent kinases; bFGF; basic fibroblast growth factor; BpT; 2-benzoylpyridine thiosemicarbazone; Bp4eT; 2-benzoylpyridine 4-ethyl-3-thiosemicarbazone; Bp44mT; 2-benzoylpyridine 4,4-dimethyl-
SUMO modification regulates the protein stability of NDRG1
Keywords: NDRG1; SUMO-2; Protein stability;
NDRG1 promotes the multidrug resistance of neuroblastoma cells with upregulated expression of drug resistant proteins
Keywords: Neuroblastoma; NDRG1; Resistance gene; Multidrug resistance; Biotherapy
N-myc downstream-regulated gene 1 (NDRG1) mediates pomegranate juice protection from apoptosis in hypoxic BeWo cells but not in primary human trophoblasts
Keywords: Apoptosis; BeWo; Hypoxia; NDRG1; Placenta; Pomegranate juice; Trophoblast;
RGS19 converts iron deprivation stress into a growth-inhibitory signal
Keywords: Regulator of G-protein signaling; N-myc downstream-regulated gene 1 protein; Cysteine string motif; Iron-binding protein; AC; adenylyl cyclase; CCI; CREB-CBP binding inhibitor; CCK-8; cell counting kit-8; CREB; cAMP response element-binding protein; CSM;
Cell type-dependent modulation of the gene encoding heat shock protein HSPA2 by hypoxia-inducible factor HIF-1: Down-regulation in keratinocytes and up-regulation in HeLa cells
Keywords: B2M; β-2 microglobulin; CAIX; carbonic anhydrase IX; CYPA; cyclophilin A; DFO; desferrioxamine; NHEK; normal human epidermal keratinocytes; HIF; hypoxia-inducible factor; H/R; hypoxia/reoxygenation; HRE; hypoxia-response element; HSP; heat shock protein;
Increased expression and activation of serum- and glucocorticoid-inducible kinase-1 (SGK1) by cadmium in HK-2 renal proximal tubular epithelial cells
Keywords: Cadmium; SGK1; NDRG1; EMD638683; HK-2 cells
SET-mediated NDRG1 inhibition is involved in acquisition of epithelial-to-mesenchymal transition phenotype and cisplatin resistance in human lung cancer cell
Keywords: NSCLC; non-small-cell lung cancer; CDDP; cisplatin; EMT; epithelial-to-mesenchymal transition; SET; SET oncoprotein; PP2A; serine/threonine protein phosphatase 2A; NDRG1; N-myc downstream regulated gene1; MMP; matrix metalloproteinase; AKT; protein kinase
Cyclin A2 and its associated kinase activity are required for optimal induction of progesterone receptor target genes in breast cancer cells
Keywords: ANOVA; analysis of variance; Cdk; cyclin dependent kinase; DST; dystonin; ECL; enhanced chemiluminescence; FACS; fluorescence activated cell sorting; FBS; fetal bovine serum; FKBP5; FK506 binding protein 5; GRE; glucocorticoid responsive element; HEF1; en
Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy
Keywords: Akt; protein kinase B; CPT-11; irinotecan; CMT4D; Charcot-Marie-Tooth disease, type 4D; DFO; deferoxamine (or desferrioxamine B); DpC; di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone; DpT; di-2-pyridylketone thiosemicarbazone; Dp44mT; di-
Histone modifications as a pathogenic mechanism of colorectal tumorigenesis
Keywords: AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem
Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells
Keywords: Chemoprevention; Colon Cancer; Oncogene; Tumor Suppressor; ACC; acetyl-CoA carboxylase; ADP; adenosine diphosphate; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; CRC; colorectal cancer; eIF4E; eukaryotic translatio
Identification of NDRG1-regulated genes associated with invasive potential in cervical and ovarian cancer cells
Keywords: NDRG1; Invasion; Cervical cancer; Ovarian cancer
Phosphorylation of NDRG1 is temporally and spatially controlled during the cell cycle
Keywords: Phosphorylation; SGK1; NDRG1; p53; Cell-cycle;
Peroxiredoxin 2 in the nucleus and cytoplasm distinctly regulates androgen receptor activity in prostate cancer cells
Keywords: AR; androgen receptor; DHT; dihydrotestosterone; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; NDRG1; N-Myc downstream regulated 1; NLS; nuclear-localizing signal; Prx; peroxiredoxin; PSA; prostate-specific antigen; SDS-PAGE; sodium dodecyl sulfateâ
NDRG1 as a biomarker for metastasis, recurrence and of poor prognosis in hepatocellular carcinoma
Keywords: Hepatocellular carcinoma; NDRG1; Biomarker; Recurrence; Metastasis
Uncovering the role of hypoxia inducible factor-1α in skin carcinogenesis
Keywords: Bax; Bcl-2-associated X protein; BCC; Basal cell carcinoma; Bcl-2; B cell lymphoma; Bcl-xL; B-cell lymphoma-extra large; BNIP3; BCL2/adenovirus E1B 19Â kDa protein-interacting protein 3; CMM; Cutaneous malignant melanoma; CBP; cyclic-AMP response element
Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells
Keywords: NDRG1; Cap43; Angiogenesis; CXC chemokines; SGK1
Cholesterol and phytosterols differentially regulate the expression of caveolin 1 and a downstream prostate cell growth-suppressor gene
Keywords: Prostate cancer; Caveolin-1; Sterols; Cholesterol; Phytosterols; NDRG1; Apoptosis; Growth-suppressor; Biomarkers; Chemoprevention
NDRG1 contributes to retinoic acid-induced differentiation of leukemic cells
Keywords: NDRG1; Leukemia; Differentiation; ATRA; C/EBPβ; PU.1
Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3β
Keywords: NDRG1; HSP90; SKG1; GSK3β; Geldanamycin; Phosphorylation
Localization of N-myc downstream-regulated gene 1 in gastric cancer tissue
Keywords: Gastric cancer; Metastasis suppressor; NDRG1; p53;
Differential genomic and proteomic profiling of glioblastoma cells exposed to terpyridineplatinum(II) complexes
Keywords: Trx; thioredoxin; TrxR; thioredoxin reductase; TPCs; terpyridineplatinum(II) complexes; I232N; 4-mercaptopyridine (4â²-chloro-2,2â²:6â²,2â³-terpyridine)platinum(II) nitrate; I252N; 2-mercaptopyridine (2â²-chloro-2,2â²:6â²,2â³-terpyridine)platinum(
N-Myc down-regulated gene 1 mediates proliferation, invasion, and apoptosis of hepatocellular carcinoma cells
Keywords: NDRG1; Hepatocellular carcinoma; siRNA; Invasion; Apoptosis
NDRG1-linked Charcot-Marie-Tooth disease (CMT4D) with central nervous system involvement
Keywords: Charcot-Marie-Tooth disease type 4D; NDRG1; Deafness; Gypsies
NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24
Keywords: NDRG1; High density lipoprotein; Apolipoprotein A-I; Apolipoprotein A-II; Charcot-Marie-Tooth disease; Neuropathy; CMT4D;