Keywords: خردل نیتروژن; Cornea; Depth of injury; Metabolomics; Nitrogen mustard; Sulfur mustard;
مقالات ISI خردل نیتروژن (ترجمه نشده)
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Keywords: خردل نیتروژن; BAL; British Anti-Lewisite (dimercaprol); COX-2; cyclooxygenase-2; CWAs; Chemical warfare agents; CX; phosgene oxime (dichloroformoxime); DMPS; 2,3-dimercapto-1-propane- sulphonic acid; IL; Interleukins; LEW; Lewisite, [dichloro(2-chlorovinyl) arsine]; MA
Keywords: خردل نیتروژن; Nitrogen mustard; Evodiamine; Hybrid; Antiproliferative activity;
Keywords: خردل نیتروژن; 1,4-Benzodiazepine; Nitrogen mustard; Blood-brain barrier; Physicochemical descriptors; ADME study; Log P; NBP assay; MTT assay;
Keywords: خردل نیتروژن; POPAM, 3-(4-(bis(2-chloroethyl)amino)phenoxy)propanoic acid; l-PAM, l-phenylalanine mustardSteroidal lactam; Antileukemic agent; Nitrogen mustard; Alkylating agent; Homo-aza-steroidal alkylators
Keywords: خردل نیتروژن; Anthraquinone; Nitrogen mustard; Synthesis; Antitumor activity;
Keywords: خردل نیتروژن; 8-oxodG; 8-oxo-7,8-dihydro-2ʹ-deoxyguanosine; NM; nitrogen mustard; IHC; immunohistochemistry; MPO; myeloperoxidase; SM; sulfur mustard; COX-2; cyclooxygenase-2; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling; CEES; 2-chloroethylethy
Keywords: خردل نیتروژن; Nitrogen mustard; Skin topical exposure; Systemic toxicity; Leucocytes; SKH-1 hairless mice; BUN; blood urea nitrogen; GI; gastrointestinal tract; H&E; hematoxylin and eosin; NM; nitrogen mustard; PALS; periarterial lymphoid sheath; SGOT; serum glutamic o
Keywords: خردل نیتروژن; Nitrogen mustard; Sesquiterpene; Anticancer; DNA cross-linking; Dehydrocostuslactone; Costunolide; SMs; sesquiterpene mustards; HepG2; human hepatocarcinoma cells; L02; human normal hepatic cells; GSH; glutathione; TBHP; t-butylhydroperoxide; DEAD; diethy
Keywords: خردل نیتروژن; Anti-melanoma prodrug; Nitrogen mustard; Hydrazine; TyrosinaseDTIC, dacarbazine (5-(3,3-dimethyl-1-triazenyl)imidazole-4-carboxamide); MTT, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PBS, phosphate buffered salineRZYUIZPARGBLEE-UHFFFAO
Keywords: خردل نیتروژن; ADR; adriamycin; BCNU; carmustine; ACA; aminocinnamic acid; CHL; chlorambucil or para-[N,N-bis(2-chloroethyl)amino]phenylbutyric acid; CNC; chloronitrocarbamoyl; CP; cisplatin; DTIC; dacarbazine; DnsEM; dansyl estramustine; EM; estramustine; EMP; estramus
Novel enmein-type diterpenoid hybrids coupled with nitrogen mustards: Synthesis of promising candidates for anticancer therapeutics
Keywords: خردل نیتروژن; 6,7-Seco-ent-kaurane diterpenoid; Nitrogen mustard; Hybrid; Antiproliferative activity; Selectivity;
Efficacy of anti-inflammatory, antibiotic and pleiotropic agents in reversing nitrogen mustard-induced injury in ex vivo cultured rabbit cornea
Keywords: خردل نیتروژن; Nitrogen mustard; Ocular injury; Dexamethasone; Doxycycline; Silibinin;
Formation and degradation of nitrogen mustard-induced MGMT-DNA crosslinking in 16HBE cells
Keywords: خردل نیتروژن; NM; nitrogen mustard; HN2; N-methyl-2,2-di(chloroethyl)amine; MGMT; O6-methylguanine-DNA methyltransferase; BAA; bifunctional alkylating agents; DPC; DNA-protein cross-link; O6BG; O6-benzylguanine; c-Myc; myelocytomatosis viral oncogene; SUMO; small ubi
Rational design, synthesis and preliminary antitumor activity evaluation of a chlorambucil derivative with potent DNA/HDAC dual-targeting inhibitory activity
Keywords: خردل نیتروژن; Chlorambucil; Nitrogen mustard; Hydroxamic acid; Anticancer;
Bifunctional alkylating agent-mediated MGMT-DNA cross-linking and its proteolytic cleavage in 16HBE cells
Keywords: خردل نیتروژن; MGMT; DNA damage and repair; DNA-protein cross-link; Bifunctional alkylating agent; Nitrogen mustard; Proteolysis; NM; nitrogen mustard; MGMT; O6-methylguanine-DNA methyltransferase; BAA; bifunctional alkylating agents; DPC; DNA-protein cross-link; DSB;
Thiazole-based nitrogen mustards: Design, synthesis, spectroscopic studies, DFT calculation, molecular docking, and antiproliferative activity against selected human cancer cell lines
Keywords: خردل نیتروژن; Antiproliferative activity; Thiazole; Nitrogen mustard; DFT calculations; Nucleobases; Topoisomerase
Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences
Keywords: خردل نیتروژن; Poly(ADP-ribose); PARP inhibitors; Sulfur mustard; Nitrogen mustard; Genotoxicity; HaCaT; Mass spectrometry; Micronucleus;
Synthesis and evaluation of a bis-3-chloropiperidine derivative incorporating an anthraquinone pharmacophore
Keywords: خردل نیتروژن; Alkylating agents; Nitrogen mustard; Anthraquinone; DNA cleavage; Intercalation;
Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC
Keywords: خردل نیتروژن; Bendamustine ester; Nitrogen mustard; Hydrolysis; Butyrylcholinesterase; Ester cleavage
A glass capillary based microfluidic electromembrane extraction of basic degradation products of nitrogen mustard and VX from water
Keywords: خردل نیتروژن; Microfluidic electromembrane extraction; Nitrogen mustard; Hollow fiber; Chemical warfare agents; Quadrupole time-of-flight mass spectrometry; Amino alcohols;
Chlorambucil (nitrogen mustard) induced impairment of early vascular endothelial cell migration – Effects of α-linolenic acid and N-acetylcysteine
Keywords: خردل نیتروژن; Nitrogen mustard; Chlorambucil; Endothelial cell; Migration; Mitochondrial membrane potential; ROS-scavenger
Mechanistic study of IR-780 dye as a potential tumor targeting and drug delivery agent
Keywords: خردل نیتروژن; IR-780 iodide; Glycolysis; Plasma membrane potential; OATP1B3; Nitrogen mustard;
Original StudyPralatrexate Alone or in Combination With Bexarotene: Long-Term Tolerability in Relapsed/Refractory Mycosis Fungoides
Keywords: خردل نیتروژن; Extracorporeal photopheresis; Folic acid inhibitor; Mycosis fungoides; Nitrogen mustard; Sézary syndrome; T cell;
Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries
Keywords: خردل نیتروژن; Sulfur mustard; Nitrogen mustard; Myeloperoxidase; Inflammation; Apoptosis; DNA damage;
Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice
Keywords: خردل نیتروژن; Skin lesions; Inflammation; Microblisters; SKH-1 hairless mice; C57BL/6 mice; Nitrogen mustard;
Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNA
Keywords: خردل نیتروژن; Boc2O; di-tert-butyl dicarbonate; CHO; Chinese hamster ovary; Et3N; triethylamine; EtOAc; ethyl acetate; HOBt; (1-hydroxybenzotriazole); ICE; immunodetection of complexes of enzyme-to-DNA; K562 cells; human erythroleukemic cells; kDNA; catenated DNA; MTS;
Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome)
Keywords: خردل نیتروژن; cutaneous T-cell lymphoma; immunomodulators; mycosis fungoides; phototherapy; prognosis; Sézary syndrome; skin-directed treatment; staging; systemic treatment; targeted therapies; topical corticosteroids; topical nitrogen mustard; topical retinoids/rexi
Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin
Keywords: خردل نیتروژن; Sulfur mustard; Nitrogen mustard; Skin p53; Skin inflammation; Skin apoptosis; ATM; Ataxia telangiectasia mutated; ATR; Ataxia telangiectasia-Rad3-related; CEES; 2-chloroethyl ethyl sulfide; GSH; Glutathione; MPO; Myeloperoxidase; NM; Nitrogen mustard; PA
The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard
Keywords: خردل نیتروژن; Cornea; Nitrogen mustard; UVB; 4-Hydroxynonenal; 9-Nitrooleic acid; Nitrosative stress;
Modified immunoslotblot assay to detect hemi and sulfur mustard DNA adducts
Keywords: خردل نیتروژن; Sulfur mustard; Nitrogen mustard; Chemical warfare agents; Vesicants
Evidence for base excision repair processing of DNA interstrand crosslinks
Keywords: خردل نیتروژن; AP endonuclease; Base excision repair; BCNU; Cisplatin; DNA glycosylase; Interstrand crosslinks; Mitomycin C; Nitrogen mustard; Oxaliplatin; Psoralen; DNA Polymerase beta
Design and synthesis of novel quinazoline nitrogen mustard derivatives as potential therapeutic agents for cancer
Keywords: خردل نیتروژن; Quinazoline; Nitrogen mustard; Anticancer; Cell cycle; Apoptosis; Xenograft modelDMAP, 4-dimethylaminopyridine; MTT, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; HepG2, human liver carcinoma cell line; SH-SY5Y, human neuroblastoma cell l
Wipe selection for the analysis of surface materials containing chemical warfare agent nitrogen mustard degradation products by ultra-high pressure liquid chromatography-tandem mass spectrometry
Keywords: خردل نیتروژن; Wipes; CWA degradation products; Nitrogen mustard; UPLC-MS/MS; HPLC-MS/MS;
Characterization and study of piperazinium salts, degradation products of nitrogen mustards by nuclear magnetic resonance spectroscopy and liquid chromatography–mass spectrometry
Keywords: خردل نیتروژن; Chemical warfare agent; Nitrogen mustard; Piperazinium salt; NMR; LC–MS
Synthesis and antitumor activity of formononetin nitrogen mustard derivatives
Keywords: خردل نیتروژن; Formononetin; Nitrogen mustard; Synthesis; Cytotoxicity; Cell cycle; Apoptosis;
Functional and inflammatory alterations in the lung following exposure of rats to nitrogen mustard
Keywords: خردل نیتروژن; Nitrogen mustard; iNOS; COX-2; CTGF; MMP-9; Lung function
Application of high performance liquid chromatography coupled to on-line solid-phase extraction-nuclear magnetic resonance spectroscopy for the analysis of degradation products of V-class nerve agents and nitrogen mustard
Keywords: خردل نیتروژن; LC-UV-SPE-NMR; VX; Nerve agents; Nitrogen mustard; Solid-phase extraction; Benzoylation
Preparation and bioevaluation of a 99mTc-labeled chlorambucil analog as a tumor targeting agent
Keywords: خردل نیتروژن; Chlorambucil; Nitrogen mustard; [99mTc(CO)3(H2O)3]+; Tumor;
DRDE-07 and its analogues as promising cytoprotectants to nitrogen mustard (HN-2)—An alkylating anticancer and chemical warfare agent
Keywords: خردل نیتروژن; Nitrogen mustard; Mechlorethamine; Percutaneous; Cytotoxicity; Cytoprotection; Oxidative stress
Enhanced detectability of fluorinated derivatives of N,N-dialkylamino alcohols and precursors of nitrogen mustards by gas chromatography coupled to Fourier transform infrared spectroscopy analysis for verification of chemical weapons convention
Keywords: خردل نیتروژن; Chemical warfare agents; Derivatization; Nitrogen mustard; Ethanolamine; GC–FTIR; Molar extinction coefficient
Lethal Effect of Benzene Nitrogen Mustard Glucoside Derivate on K562 Cells
Keywords: خردل نیتروژن; Nitrogen mustard; Benzene nitrogen mustard glucoside derivate; K562 cell; Antitumor drug;
Stability of the nitrogen mustard mechlorethamine in novel formulations for dermatological use
Keywords: خردل نیتروژن; Mechlorethamine; Nitrogen mustard; Stability; Dermal delivery; Aquaphor®; Transcutol®
Modifications and insights into a method for the analysis of the nitrogen mustard mechlorethamine by high-performance liquid chromatography
Keywords: خردل نیتروژن; Nitrogen mustard; Mechlorethamine; Analysis; Derivatization; High-performance liquid chromatography;
Tissue injury by hot fluid containing nitrogen mustard
Keywords: خردل نیتروژن; Nitrogen mustard; Eye; Inhalation; Neutrophil; Burns
Extraction of chemical warfare agents from water with hydrophilic–lipophilic balance and C18 cartridges: Comparative study
Keywords: خردل نیتروژن; Solid-phase extraction; Hydrophilic–lipophilic balance; Chemical warfare agents; Sarin; Sulfur mustard; Nitrogen mustard; Chemical weapons convention; Verification
Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats
Keywords: خردل نیتروژن; Nitrogen mustard; Lung damage; Nitric oxide; Peroxynitrite
Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard
Keywords: خردل نیتروژن; Nitrogen mustard; Lung damage; Nitrosative stress; Oxidative stress; Melatonin
Aquatic toxicity of nitrogen mustard to Ceriodaphina dubia, Daphnia magna, and Pimephales promelas
Keywords: خردل نیتروژن; Daphnia magna; Ceriodaphnia dubia; Pimephales promelas; Nitrogen mustard;
On-matrix derivatisation-extraction of precursors of nitrogen- and sulfur-mustards for verification of chemical weapons convention
Keywords: خردل نیتروژن; Nitrogen mustard; Sulfur mustard; Chemical weapons convention; Verification; Derivatisation; Extraction;