Wipe selection for the analysis of surface materials containing chemical warfare agent nitrogen mustard degradation products by ultra-high pressure liquid chromatography-tandem mass spectrometry

► Chemical warfare agent nitrogen mustard degradation products were analyzed. ► Wipe selection for surface sampling investigated to discover optimal wipe. ► Porous and non-porous surfaces were analyzed from a common urban environment setting. ► UPLC-ESI-MS/MS analysis was nearly four times faster than HPLC-MS/MS.