Glutamate release from astrocytes as a non-synaptic mechanism for neuronal synchronization in the hippocampus
Keywords: Glia; Glutamate; Synchrony; Epilepsy; Calcium; NMDA
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4-Substituted-8-(1-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a novel class of highly selective GlyT1 inhibitors with superior pharmacological and pharmacokinetic parameters
Keywords: GlyT1; GlyT2; NMDA; Schizophrenia; Transporter; Glycine; Spiropiperidine
Enhancement of long-term potentiation at CA1-subiculum synapses in MK-801-treated rats
Keywords: MK-801; NMDA; Subiculum; Schizophrenia; LTP
Effect of NMDA antagonists on the death of cerebellar granule neurons at different ages
Keywords: Cerebellar granule neurons; Depolarizing conditions; Development; Neuronal survival; NMDA; Programmed cell death or apoptosis
Increase in tyrosine phosphorylation of the NMDA receptor following the induction of status epilepticus
Keywords: NMDA; Pilocarpine; Status epilepticus; Phosphorylation; Src; Pyk2;
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus
Keywords: Pilocarpine; Seizures; Status epilepticus; NMDA; Fluoxetine; Amitriptyline; Ketamine; Gabapentin; Pimozide
Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats
Keywords: Hippocampus; Diabetes mellitus; Synaptic transmission; Long-term potentiation; NMDA; AMPA
Supraspinally administered agmatine prevents the development of supraspinal morphine analgesic tolerance
Keywords: NMDA; Nitric oxide synthase; Neuroprotection; Intracerebroventricular
Repeated injection of MK801: An animal model of schizophrenia?
Keywords: [1-13C]glucose; [1,2-13C]acetate; MK801; NMDA; GABA; Glutamate; Metabolism; NMR spectroscopy
Prenatal alcohol exposure alters GABAAα5 expression: A mechanism of alcohol-induced learning dysfunction
Keywords: Fetal alcohol syndrome; GABA; NMDA; Mouse; Learning
Preliminary evidence for a link between schizophrenia and NMDA–glycine site receptor ligand metabolic enzymes, d-amino acid oxidase (DAAO) and kynurenine aminotransferase-1 (KAT-1)
Keywords: Schizophrenia; NMDA; DAAO; KAT-1; Gene expression
Effects of toluene on seizures induced by convulsants acting at distinct ligand-gated ion channels
Keywords: Toluene; Seizures; NMDA; Bicuculline; Picrotoxin; Nicotine; Strychnine
Inhibition of the serotonin-induced inward current by dextromethorphan in rat nodose ganglion neurons
Keywords: 5-HT; 5-hydroxytryptamine; BD-1047; N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine; mCPBG; 1-(m-chlorophenyl)-biguanide hydrochloride; NMDA; N-methyl-d-aspartic acid; 5-HT3 receptor; Dextromethorphan; Patch-clamp recording; Vagal aff
Extended therapeutic time window after focal cerebral ischemia by non-competitive inhibition of AMPA receptors
Keywords: AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; CBF; cerebral blood flow; FDA; Food and drug administration; IL-1β; interleukin-1β; MCA; middle cerebral artery; NBQX; 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzol[f]quinoxaline; NMDA; N-methyl-d-a
Prevention of alcohol-induced learning deficits in fetal alcohol syndrome mediated through NMDA and GABA receptors
Keywords: Fetal alcohol syndrome; Alcohol; NMDA; GABA; Learning; Neurotrophic factors
Unilateral lesion of the subthalamic nucleus enhances cortical fos expression associated with focally evoked seizures in the rat
Keywords: Basal ganglia; Epilepsy; NMDA; Bicuculline; Hippocampus
Neuronal cell death due to glutamate excitotocity is mediated by P38 activation in the rat cerebral cortex
Keywords: AMPA; NMDA; GluR2; p38/SAPK; REST; Fas-L; Bcl-2
Effects of SDF-1α and gp120IIIB on apoptotic pathways in SK-N-SH neuroblastoma cells
Keywords: CXCR4; NMDA; gp120; SDF-1α; HIV; Neurotoxicity; SK-N-SH;
Design and synthesis of 4-substituted-8-(2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a novel class of GlyT1 inhibitors: Achieving selectivity against the μ opioid and nociceptin/orphanin FQ peptide (NOP) receptors
Keywords: GlyT1; GlyT2; NMDA; Schizophrenia; Transporter; Glycine; Spiropiperidine;
The entorhinal cortex plays a role in extinction
Keywords: Learning; Memory; Extinction; Entorhinal cortex; AP5; NMDA; Anisomycin; Protein synthesis; KN-93; CaMKII; PD98059; ERK1/2
Chronic treatment with antidepressant drugs reversibly alters NMDA mediated regulation of extracellular 5-HT in rat frontal cortex
Keywords: Antidepressants; NMDA; 5-HT; Cortex; Microdialysis
Fear conditioning performance and NMDA receptor subtypes: NR2A differential expression in the striatum
Keywords: Binding; Fear conditioning; In situ hybridization; [3H]MK-801; NMDA; NR2A; NR2B;
Chicken cerebellar granule neurons rapidly develop excitotoxicity in culture
Keywords: Chicken granule neurons; Excitotoxicity; Glutamate; NMDA
NMDA-induced preconditioning attenuates synaptic plasticity in the rat hippocampus
Keywords: Preconditioning; Long-term potentiation; NMDA; Nitric oxide
Prepulse inhibition is different in two inbred mouse strains (CPB-K and BALB/cJ) with different hippocampal NMDA receptor densities
Keywords: AMPA; alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid; ASR; acoustic startle response to startle stimulus alone; NMDA; N-methyl-d-aspartate; NOSTIM; non-stimulus; PCP; phencyclidine; PPI; prepulse inhibition of the startle reflex; PREPULSE; prep
Sensitivity of rat temporalis muscle afferent fibers to peripheral N-methyl-d-aspartate receptor activation
Keywords: nociception; craniofacial; mechanical; temporomandibular; jaw; trigeminal; CV; conduction velocity; NMDA; N-methyl-d-aspartate; PPT; pressure pain threshold;
Antegrade cerebral perfusion reduces apoptotic neuronal injury in a neonatal piglet model of cardiopulmonary bypass
Keywords: 1; 19; 27; ACP; antegrade cerebral perfusion; CPB; cardiopulmonary bypass; CREB; cAMP response element binding protein; DHCA; deep hypothermic circulatory arrest; H&E; hematoxylin and eosin; NMDA; N-methyl-D-aspartate; TUNEL; terminal deoxynucleotidyl tra
Bipolar mania and plasma amino acids: Increased levels of glycine
Keywords: Bipolar disorder; Mania; Glutamate; Glycine; Tryptophan; NMDA
Creatine prevents behavioral alterations caused by methylmalonic acid administration into the hippocampus of rats in the open field task
Keywords: MMA; methylmalonic acid; MMAemia; methylmalonic acidemia; NMDA; N-methyl-d-aspartate; MK-801; dizocilpine maleate; ANOVA; analysis of variance; S.E.M.; standard error of the mean; SPSS; Statistical Package of the Social Sciences; NaCl; sodium chloride; Me
Estrus variation in anticonflict-like effects of the mGlu5 receptor antagonist MTEP, microinjected into lateral septal nuclei of female Wistar rats
Keywords: Conflict behavior; Estrous cycle; Lateral Septum; MTEP; NMDA
Antidepressant-like and anxiolytic-like actions of the mGlu5 receptor antagonist MTEP, microinjected into lateral septal nuclei of male Wistar rats
Keywords: DRL-72 s, differential reinforcement of the low-rate 72 s; IRT, inter-response time.Antidepressant-like; Anxiolytic-like; DRL-72 s; Elevated plus-maze; Lateral Septum; MTEP; NMDA
Development of GABA and glutamate signaling at the GnRH neuron in relation to puberty
Keywords: GABA; GnRH; LHRH; Puberty; Glutamate; NMDA
NMDA receptor antagonists antagonize the facilitatory effects of post-training intra-basolateral amygdala NMDA and physostigmine on passive avoidance learning
Keywords: NMDA; DL-AP5; MK-801; Physostigmine; Passive avoidance learning; Retention; Basolateral amygdala; (Rats)
NMDA receptor blockers prevents the facilitatory effects of post-training intra-dorsal hippocampal NMDA and physostigmine on memory retention of passive avoidance learning in rats
Keywords: NMDA; MK-801; DL-AP5; Physostigmine; Passive avoidance learning; Retention; Dorsal hippocampus; Rat
Magnocellular contributions to impaired motion processing in schizophrenia
Keywords: Schizophrenia; Motion; Magnocellular; Visual; NMDA
Activity-dependent shedding of heparin-binding EGF-like growth factor in brain neurons
Keywords: HB-EGF; ErbB1; EGF; Shedding; TACE; Glutamate; NMDA
Adenosine A1 receptors decrease thalamic excitation of inhibitory and excitatory neurons in the barrel cortex
Keywords: somatosensory; glutamate; interneurons; spiny stellate cells; ACSF; artificial cerebrospinal fluid; AHP; afterhyperpolarization; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; APV; dl-2-amino-5-phosphonopentanoic acid; CNQX; 6-cyano-7-nitroqu
A novel neuronal cell line derived from the ventrolateral region of the suprachiasmatic nucleus
Keywords: circadian rhythm; N14.5; NMDA; NR2B subunit; MAPK; suprachiasmatic nucleus; AVP; arginine vasopressin; bFGF; basic fibroblast growth factor; CNPase; 2â²-3â²-cyclic-nucleotide 3â²-phosphodiesterase; dbcAMP; dibutyryl cAMP; Dex; dexamethasone; EGF; epide
The effect of N-methyl-d-aspartate receptor blockade on acetylcholine efflux in the dorsomedial striatum during response reversal learning
Keywords: striatum; NMDA; acetylcholine; microdialysis; reversal learningACh, acetylcholine; aCSF, artificial cerebrospinal fluid; AP-5, 2-amino-5-phosphopentanoic acid; NMDA, N-methyl-d-aspartate
Repeated maternal separation of male Wistar rats alters glutamate receptor expression in the hippocampus but not the prefrontal cortex
Keywords: AMPA; NMDA; Development; mRNA; PCR; Stress;
Neuroprotective effect of the stearic acid against oxidative stress via phosphatidylinositol 3-kinase pathway
Keywords: Stearic acid; Brain ischemia; Anoxia; NMDA; Hydrogen peroxide
Role of cellular prion protein on LTP expression in aged mice
Keywords: APV, 2-amino-5-phosphonopentanoic acid; cAMP, cyclic AMP; DIG, digoxigenin; ECM, extracellular matrix; EPSP, excitatory post-synaptic potentials; HIS, in situ hybridization; LTD, long-term depression; LTP, long-term potentiation; MK-801, dizocilpine; NMDA
Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice
Keywords: Excitotoxicity; Free radicals; Kynurenine monooxygenase; Kynurenine pathway; Microglia; Neurodegeneration; NMDA
20(S)-ginsenoside Rh2, a newly identified active ingredient of ginseng, inhibits NMDA receptors in cultured rat hippocampal neurons
Keywords: Ginseng; Ginsenoside Rh2; (R)- or (S)-stereoisomer; NMDA; Polyamine-binding site; Patch-clamp
Dopamine D2 receptor-mediated G protein activation assessed by agonist-stimulated [35S]guanosine 5â²-O-(γ-thiotriphosphate) binding in rat striatal membranes
Keywords: CHO; Chinese hamster ovary; EC50; the concentration eliciting the half-maximal stimulation; %Emax; the percent maximal increase above the basal binding; G protein; guanine nucleotide-binding regulatory protein; GTPγS; guanosine 5â²-O-(γ-thiotriphosphat
The effect of acidosis on adenosine release from cultured rat forebrain neurons
Keywords: ACE; acetate; AN; adenine nucleotides; ADO; adenosine; BCECF-AM; 2â²,7â²-bis(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester; CNTs; concentrative nucleoside transporters; CNS; central nervous system; DIV; days in vitro; EIPA; 5-(N)-ethyl-N-i
Effects of flufenamic acid on fictive locomotion, plateau potentials, calcium channels and NMDA receptors in the lamprey spinal cord
Keywords: ICAN; Network; Central pattern generator; Membrane potential oscillations; NMDA
Amphetamine-induced disruption of prepulse inhibition in mice with reduced NMDA receptor function
Keywords: Acoustic startle; Amphetamine; Mouse; NMDA; Schizophrenia; Sensorimotor gating;
Naloxone, not proglumide or MK-801, alters effects of morphine preexposure on morphine-induced taste aversions
Keywords: Taste aversion; UCS preexposure; Tolerance; Morphine; Proglumide; MK-801; Naloxone; NMDA; CCK;
Differential effects of cocaine and ketamine on time estimation: Implications for neurobiological models of interval timing
Keywords: Timing; Time perception; Dopamine; Glutamate; NMDA; Striatum; Cortex