Keywords: Autism; Enzymatic antioxidants; Oxidative stress; Neutrophils; Monocytes; ASD; Autism spectrum disorder; NOX2; NADPH oxidase; iNOS; inducible nitric oxide synthase; ROS; reactive oxygen species; TDC; typically developing control; SOD; Superoxide dismutase
مقالات ISI (ترجمه نشده)
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Keywords: PTSD; Metabolomics; Glycomics; Clinical data; Animal models; Theranostic biomarkers; Patients; ACTH; adenocorticotropic hormone; APCI; atmospheric pressure chemical ionization; BDNF; brain derived neurotropic factor; CE; capillary electrophoresis; CE-MS;
Keywords: ICH; intracerebral hemorrhage; APN; adiponectin; Lenti.APN; Lentivirus overexpression of APN; BBB; blood-brain barrier; SOD; superoxide dismutase; GSH; glutathione; GSSG/GSH; the ratio of oxidized glutathione to reduced glutathione; MDA; malondialdehyde
Keywords: AGEs; advanced glycation end-products; CAD; coronary artery disease; CRP C; reactive protein; CTGF; connective tissue growth factor; DAG; diacyl glycerol; DCM; diabetic cardio-myopathy; DFU; diabetic foot ulcer; eNOS; endothelial nitric oxide synthase; FO
Keywords: Ethanol; SR Ca2+-leak; CaMKII; Holiday heart syndrome; NOX2;
Keywords: BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; FGFR; fibroblast growth factor receptor; GLT-1; glutamate transporter 1; ICH; intracerebral hemorrhage; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; NDS; neurological
Keywords: Preload; Afterload; Calcium sparks; Microdomains; Mechanotransduction; Stretch-induced arrhythmias; AP; action potential; AT; axial tubule; Ca2+; calcium; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CICR; Ca2+ induced Ca2+ release; GSMTx4; Grammo
Keywords: Arg1; arginase 1; Bregs; regulatory B cells; COX2; cyclooxygenase 2; Gr-MDSC; granulocytic MDSC; HMGB1; high mobility group box protein 1; iNOS or NOS2; inducible nitric oxide synthase; l-arg; l-arginine; MDSCs; myeloid-derived suppressor cells; MO-MDSC;
Keywords: EEL; external elastic lamina; IEL; internal elastic lamina; I/M ratio; intima/media ratio; MNC; peripheral blood mononuclear cells; NF1; neurofibromatosis type 1; Nf1+/-; heterozygous for the Nf1 allele; Nf1+/-;p47-/-; heterozygous for the Nf1 allele an
Keywords: CP; 3-carboxy-proxyl; CPH; 1-Hydroxy-3-carboxy-2,2,5,5-tetramethylpyrrolidine; Nav1.5; Voltage gated sodium channel isoform; NCAM; Neural cell adhesion molecule; NEM; N-ethylmaleimide; NMJ; Neuromuscular junction; NOX2; NAD(P)H oxidase 2; Prdx; Peroxiredo
Keywords: CD39; M1/M2 microglia; Motoneuron; Oligodendrocyte; P2X7; P2Y12; ALS; amyotrophic lateral sclerosis; BBG; Brilliant Blue G; BDNF; brain-derived neurotrophic factor; BzATP; 2â²-3â²-O-(benzoyl-benzoyl) ATP; fALS; familial ALS; FUS; fused in sarcoma; HuR
Keywords: angiotensin II; cardiac contractility; cardiac hypertrophy; cardiomyocyte; NADPH oxidase; Nox2; reactive oxygen species;
Keywords: TAAs; Tumor-associated antigens; MUC1; Mucin 1; HER2/neu; Human epidermal growth factor receptor 2; CEA; Carcinoembryonic antigen; HLA; Human leukocyte antigen; TSA; Tumor-specific antigen; TAP; Transporter associated with antigen processing; ER; Endoplas
Keywords: Insulin; Ca2+; Cardiomyocytes; Myotubes; IP3R; RyR; GLUT4; NOX2; Mitochondria
Keywords: FACS; fluorescence activated cell sorting; MHCI; MHC class I molecules; MHCII; MHC class II molecules; APC; antigen-presenting cells; DC; dendritic cells; TCR; T cell receptor; MVB; multi-vesicular body; ILV; intraluminal vesicles; MARCH; membrane-associa
Keywords: bbt; Branchiostoma belcheri tsingtauense; CYBA; cytochrome b light chain; DHE; dihydroethidium; DPI; diphenyleneiodonium; DUOX; dual oxidases; NAC; N-acetyl-l-cysteine; NBT; nitroblue tetrazolium salt; NCF; neutrophil cytosolic factor; NOX2; NADPH oxidase
Increased oxidative stress in the cerebellum and peripheral immune cells leads to exaggerated autism-like repetitive behavior due to deficiency of antioxidant response in BTBR Tâ¯+â¯tf/J mice
Keywords: Autism; Enzymatic antioxidants; Oxidants; Immune cells; Cerebellum; NOX2; NADPH oxidase; iNOS; inducible nitric oxide synthase; ROS; reactive oxygen species; SOD; Superoxide dismutase; GPx; Glutathione peroxidase; GR; Glutathione reductase;
Regional up-regulation of NOX2 contributes to the differential vulnerability of outer hair cells to neomycin
Keywords: Outer hair cell; NOX2; Apoptosis; Reactive oxygen species; Hearing loss;
Short chain fatty acid, acetate ameliorates sepsis-induced acute kidney injury by inhibition of NADPH oxidase signaling in T cells
Keywords: Sepsis; NOX2; ROS; T cell; Antioxidants; Acute kidney injury;
BLT1-mediated O-GlcNAcylation is required for NOX2-dependent migration, exocytotic degranulation and IL-8 release of human mast cell induced by Trichomonas vaginalis-secreted LTB4
Keywords: Trichomonas vaginalis; Human mast cells; BLT1; O-GlcNAcylation; NOX2; Leukotriene B4;
Down-regulation of microRNA-27b promotes retinal pigment epithelial cell proliferation and migration by targeting Nox2
Keywords: miR-27b; PDGF-BB; Retinal pigment epithelium; Proliferation and migration; Nox2;
Mechanisms underlying modulation of podocyte TRPC6 channels by suPAR: Role of NADPH oxidases and Src family tyrosine kinases
Keywords: Apo; apocynin; CGT; cilengitide; CKD; chronic kidney disease; FSGS; focal and segmental glomerulosclerosis; gp91phox; catalytic subunit of NADPH oxidase 2; Nox2; NADPH oxidase 2; Nox4; NADPH oxidase 4; NSC23766; N6â[2â[[4â(Diethylamino)â1âmethyl
Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway
Keywords: Aβ; β-amyloid; CNS; central nervous system; CR3; complement receptor 3; DAMPs; damage associated molecular patterns; DEPs; diesel exhaust particles; DHE; dihydroethidium; Erk; extracellular regulated protein kinases; HMGB1; high-mobility group box 1; Ib
Hydrogen peroxide derived from NADPH oxidase 4- and 2 contributes to the endothelium-dependent vasodilatation of intrarenal arteries
Keywords: ACh; acetylcholine; COX; cyclooxygenase; CYP; cytochrome P450; EC; endothelial cell; EDH; endothelium-derived-hyperpolarization; eNOS; endothelial nitric oxide synthase; ER; endoplasmic reticulum; H2O2; hydrogen peroxide; NADPH; nicotinamide adenine dinuc
Antioxidant activity from extra virgin olive oil via inhibition of hydrogen peroxide-mediated NADPH-oxidase 2 activation
Keywords: EVOO; NOX2; Platelets; Polyphenols; Scavenger activity; Vitamin E;
NADPH oxidase 2 (NOX2): A key target of oxidative stress-mediated platelet activation and thrombosis
Keywords: Platelet; Antiplatelet; Oxidative stress; NADPH oxidase; NOX2;
Alpinumisoflavone rescues glucocorticoid-induced apoptosis of osteocytes via suppressing Nox2-dependent ROS generation
Keywords: Alpinumisoflavone; Osteocyte; Apoptosis; ROS; Nox2; AMPK;
Association of NOX2 subunits genetic variants with autoimmune diseases
Keywords: NOX2; NADPH oxidase isoform 2; Ncf1; neutrophil cytosolic factor 1; ROS; reactive oxygen species; SNP; single nucleotide polymorphism; CNV; copy number variation; RA; rheumatoid arthritis; PsA; psoriatic arthritis; MS; multiple sclerosis; SLE; systemic lu
Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy
Keywords: DMD; Duchenne muscular dystrophy; DGC; dystrophin-associated glycoprotein complex; ECM; extracellular matrix; SIRT1; Sirtuin1; PGC-1α; peroxisome proliferator-activated receptor γ coactivator 1α; PPARγ; peroxisome proliferator-activated receptor γ; B
Original articleNOX2-ROS-HIF-1α signaling is critical for the inhibitory effect of oleanolic acid on rectal cancer cell proliferation
Keywords: Rectal cancer; Oleanolic acid; Proliferation; NOX2; HIF-1α;
Conversion of NOX2 into a constitutive enzyme in vitro and in living cells, after its binding with a chimera of the regulatory subunits
Keywords: AA; all-cis-Arachidonic Acid; CCCP; carbonyl cyanide 3-chlorophenyl hydrazone; CGD; Chronic Granulomatous Disease; cyt c; cytochrome c; cyt b558; flavocytochrome b558; DPI; Diphenylene Iodonium; DISCO; Dichroism, Imaging and mass Spectrometry for Chemical
NOX isoforms in the development of abdominal aortic aneurysm
Keywords: Abdominal aortic aneurysms (AAA); Angiotensin II (Ang II); Nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase/NOX); NOX1; NOX2; NOX4; p47phox; Endothelial nitric oxide synthase (eNOS) uncoupling; Dihydrofolate reductase (DHFR); Superoxide;
Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction
Keywords: HG; high glucose; GEFs; guanine nucleotide exchange factors; GSIS; glucose-stimulated insulin secretion; NOD mice; nonobese diabetic mice; Nox2; phagocyte-like NADPH oxidase; Rac1; Ras-related C3 botulinum toxin substrate 1; ROS; reactive oxygen species;
NADPH oxidase-derived H2O2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease
Keywords: BDNF; brain derived neurotrophic factor; GDNF; glia derived neurotrophic factor; GFAP; glial fibrillary protein; Iba-1; ionized calcium binding adaptor molecule 1; IL-1β; interleukin-1β; LPS; lipopolysaccharide; LME; l-leucine-methyl esther; MAPK; mitog
Nitroarachidonic acid (NO2AA) inhibits protein disulfide isomerase (PDI) through reversible covalent adduct formation with critical cysteines
Keywords: AA; arachidonic acid; NO2AA; nitroarachidonic acid; NOX2; phagocytic NADPH oxidase; NOS2; inducible nitric oxide synthase; ROS; reactive oxygen species; RNS; reactive nitrogen species; PDI; Protein disulfide isomerase; DTT; dithiothreitol; GFP; green fluo
NADPH oxidase-2 does not contribute to β-cell glucotoxicity in cultured pancreatic islets from C57BL/6J mice
Keywords: NOX2; roGFP sensors; Pancreatic β-cell; Insulin secretion; Apoptosis;
Celastrol attenuates angiotensin II mediated human umbilical vein endothelial cells damage through activation of Nrf2/ERK1/2/Nox2 signal pathway
Keywords: Celastrol; Angiotensin II; Reactive oxygen species; Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase; Nuclear factor erythroid 2-related factor 2; Nox2;
VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release
Keywords: Dendritic cells; VAMP8; NOX2; Cross-presentation; Lipid peroxidation;
Combination treatment with erlotinib and ampelopsin overcomes erlotinib resistance in NSCLC cells via the Nox2-ROS-Bim pathway
Keywords: NSCLC; Non-small cell lung cancer; Nox2; nicotinamide adenine dinucleotide phosphate oxidase 2; ROS; reactive oxygen species; NAC; N-acetyl cysteine; Bim; B-cell lymphoma 2 interacting mediator of cell death; Erlotinib; Ampelopsin; ROS; Nox2; NSCLC;
Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC
Keywords: NOX2; Reactive oxygen species; Adult neurogenesis; in vitro neural differentiation; Neural stem/progenitor cells; Induced pluripotent stem cells (iPSC);
Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium
Keywords: 129; 129S1/SvimJ; B6; C57BL6/J; DKO; double knockout of GPx1 and GPx2 genes; DUOX 2; dual oxidase-2; Duoxa; Duox activator; Duoxa-TKO; triple-knockout mice with disrupted Duoxa, GPx1 and GPx2 genes; DSS; dextran sodium sulfate; DTI; di-2-thienyliodonium;
EBV-encoded EBNA1 regulates cell viability by modulating miR34a-NOX2-ROS signaling in gastric cancer cells
Keywords: EBV; EBNA1; NOX2; ROS; miR34a;
Renal protective effect and action mechanism of Huangkui capsule and its main five flavonoids
Keywords: CRF; Chronic renal failure; ESRD; end-stage renal disease; EMT; Epithelial to mesenchymal transition; HK-2; Human kidney proximal tubule epithelial cell; QT; quercetin; IQT; isoquercitrin; HY; hyperoside; GG; gossypetin-8-O-β-D-glucuronide; QG; quercetin
Regulatory role of NADPH oxidase 2 in the polarization dynamics and neurotoxicity of microglia/macrophages after traumatic brain injury
Keywords: TBI; traumatic brain injury; ROS; reactive oxygen species; NF-κB; Nuclear factor-kappa B; APO; apocynin; VE; vehicle; LPS; lipopolysaccharides; IFN-γ; interferon-γ, IL, interleukin; TNF; tumor necrosis factor; HEt; hydroethidine; ROI; regions of intere
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc
Keywords: DN; diabetic nephropathy; ROS; reactive oxygen species; HG; high-glucose; SIRT1; sirtuin-1; Ac-H3; acetyl-histone H3; STZ; streptozotocin; AMPK; AMP-activated protein kinase; ECM; extracellular matrix; Nox2; NADPH oxidase 2; EMT; tubular epithelial-mesenc
North American ginseng inhibits myocardial NOX2-ERK1/2 signaling and tumor necrosis factor-α expression in endotoxemia
Keywords: North American ginseng; TNF-α; NADPH oxidase; Nox2; Lipopolysaccharide; Sepsis;
Aminoguanidine treatment increased NOX2 response in diabetic rats: Improved phagocytosis and killing of Candida albicans by neutrophils
Keywords: AGEs; Advanced glycation end products; AMG; Aminoguanidine; DM; Diabetes mellitus; HbA1c; glycated hemoglobin; HOCl; hypochlorous acid; NO; Nitric oxide; iNOS; Nitric oxide synthase; NOX2; phagocyte NADPH oxidase system; ROS; Reactive oxygen species; ONOO
Extra virgin olive oil rich in polyphenols modulates VEGF-induced angiogenic responses by preventing NADPH oxidase activity and expression
Keywords: Matrix metalloproteinases; Nox2; Nox4; p47phox; Oxidative stress; Endothelial cells;
The neutral sphingomyelinase-2 is involved in angiogenic signaling triggered by oxidized LDL
Keywords: Cer; ceramide; CAM; chorioallantoic membrane; HMEC-1; Human Microvascular Endothelial Cell-1; LDL; low density lipoproteins; mAb; monoclonal antibodies; nSMase2; neutral sphingomyelinase-2; oxLDL; oxidized LDL; ROS; reactive oxygen species; H2O2; hydrogen
NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury
Keywords: NADPH oxidase; NOX2; Traumatic brain injury; Microglia; Macrophage; Neuroinflammation; M1-/M2-like; Neurodegeneration;