Keywords: عامل تنفسی هسته ای 1; Mitochondrial dysfunction; Testosterone; Mitophagy; Hypogonadism; BNIP3; BCL2/adenovirus E1B 19â¯kDa protein-interacting protein 3; TA; tibialis anterior; ERK 1/2; extracellular signal-regulated kinase 1/2; AMPK; 5â² AMP-activated protein kinase; LC3;
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Keywords: عامل تنفسی هسته ای 1; AA; Antimycin A; ADFI; average daily feed intake; ADG; average daily gain; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; CAT; catalase; CR; caloric restriction; CS; citrate synthase; cyt b; cytochrome b; ESRRA; estrogen-related receptor
Keywords: عامل تنفسی هسته ای 1; Dihydrocapsiate; HFD; Obesity; Glucose intolerance; Hepatic steatosis; ACOX1; Acyl-CoA oxidase 1; ADIPO; adiponectin; AIN; American Institute of Nutrition; ANOVA; 1-way analysis of variance; BAT; brown adipose tissue; BMI; body mass index; C/EBPβ; CCAAT/
Keywords: عامل تنفسی هسته ای 1; AIF; apoptosis-inducing factor; ASL; argininosuccinate lyase; ASS; argininosuccinate synthetase; AST; aspartate aminotransferase; BER; base excision repair; cGC; cyclic guanylyl cyclase; CNS; central nervous system; DRP-1; dynamin-related protein 1; EAE;
Keywords: عامل تنفسی هسته ای 1; IL-6; interleukin-6; ND; normal diet; HFD; high fat diet; FAs; fatty acids; CD36; cluster of differentiation 36; MCP-1; monocyte chemoattractant protein 1; PPARα; peroxisome proliferator-activated receptor α; CPT-1; carnitine palmitoyltransferase 1; End
Keywords: عامل تنفسی هسته ای 1; AP-1; activating protein 1; ATM; ataxia telangiectasia mutated kinase; BFU-E; erythroid burst-forming unit; CKD; chronic kidney disease; COPD; chronic obstructive pulmonary disease; DUOXs; dual oxidases; eGFR; estimated glomerular filtration rate; ESRD; e
Keywords: عامل تنفسی هسته ای 1; AGO; adrenal gland oncocytoma; BHDS; Birt-Hogg-Dubée syndrome; CCRCC; clear cell renal cell carcinoma; CD; mtDNA common deletion; DAP3; death-associated protein 3; DCA; dichloroacetate; ERRα; estrogen-related receptor alpha; ETC; electron transport chai
Keywords: عامل تنفسی هسته ای 1; AIPC; Androgen-independent prostate cancer; AKAP1; cAMP signaling; AML; acute myeloid leukemia; BAK; Bcl-2 homologous antagonist killer; BAX; Bcl-2-associated X protein; BCL-2; B-cell lymphoma 2; BMRP; BCL-2 interacting mitochondrial ribosomal protein; C7
Keywords: عامل تنفسی هسته ای 1; MB; methylene blue; ND; neurodegenerative diseases; CNS; central nervous system; ETC; electron transport chain; ROS; reactive oxygen species; Nrf2/ARE; NF-E2-related factor 2/antioxidant response element; NRF-1; nuclear respiratory factor 1; TFAM; transcr
Keywords: عامل تنفسی هسته ای 1; ABCA1; ATP-binding cassette transporter 1; ABCG1; ATP Binding Cassette G1; AMPK; 5â²AMP-activated protein kinase; AP-1; activator protein 1; apo A-I; apolipoproteins A-I; AT; adipose tissue; CCK-1; cholecystokinin; CD; Crohn's disease; CVD; cardiovascula
Keywords: عامل تنفسی هسته ای 1; AA; antimycin; AICAR; 5-aminoimidazole-4-carboxamide-1-b-d-ribofuranoside; AMPK; 5â² AMP-activated protein kinase; Ap5A; P1,P5-Di(adenosine-5â²) pentaphosphate; ASC; ascorbate; BrdU; bromodeoxyuridine; CC; Compund C; CNâ; Â cyanide; DCF; dichlorofluor
Keywords: عامل تنفسی هسته ای 1; Drp1; Dynamin-related protein1; GSK3β; Glucose synthase kinase 3 beta; CDK5; Cyclin dependent kinase 5; miRNA; micro ribonucleic acid; NMDAR; N-methyl-D-aspartate receptor; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; AD; Alzhei
Keywords: عامل تنفسی هسته ای 1; Blood-brain barrier; Neurovascular unit; Glycolysis; Lactate; Brain development; AGEs; advanced glycation end products; ADP; ribose-adenosine diphosphate ribose; ATP; adenosine triphosphate; BBB; blood-brain barrier; BDNF; brain-derived growth factor; C
Keywords: عامل تنفسی هسته ای 1; GSIS; glucose-stimulated insulin secretion; T; testosterone; DHT; 5α-dihydrotestosterone; AR; androgen receptor; Tfam; mitochondrial transcription factor A; PGC-1α; peroxisome proliferator-activated receptor γ coactivator 1α; NRF1; nuclear respiratory
Keywords: عامل تنفسی هسته ای 1; AICAR; 5â²aminoimidazole-4-carboxyamide-ribonucleoside; AD; Alzheimer's disease; ATF-2; activating transcription factor-2; AMPK; AMP-activated protein kinase; Bnip3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BnipL/Nix; BCL2/adenovirus E1B 19Â
Keywords: عامل تنفسی هسته ای 1; ALAS1; 5-aminolevulinate synthase 1; ANT; anthracycline; BVR A; biliverdin reductase A; COX1, COX4; mitochondrial and nuclear genome-encoded complex IV subunits, respectively; DAU; daunorubicin; DEX; dexrazoxane; FU; post-treatment follow up; GSH; reduced
The multifaceted role of glutathione S-transferases in cancer
Keywords: عامل تنفسی هسته ای 1; Glutathione-S transferase; Carcinogenesis; Biomarkers; Drug resistance; Tumor suppressor; AD; Aricaidine; AP-1; Activator protein 1; ASK1; Apoptosis signal-regulating kinase; CSC; cancer stem cells; EGFR; Epidermal growth factor receptor; GSH; glutathione
Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1α/mitochondrial biosynthesis pathway
Keywords: عامل تنفسی هسته ای 1; ADH; alcohol dehydrogenase; ALD; Alcoholic liver disease; ALDH; aldehyde dehydrogenase; CPT-1α; carnitine palmitoyl transterase-1α; CR; calorie restriction; CS; citrate synthase; CYP2E1; cytochrome P450 2E1; FASN; fatty acid synthase; NAD+; nicotinamide
BDNF mimetic alleviates body weight gain in obese mice by enhancing mitochondrial biogenesis in skeletal muscle
Keywords: عامل تنفسی هسته ای 1; 7,8-DHF; 7,8-Dihydroxyflavone; ACC; accetyl CoA carboxylase; AdipoQ; adiponectin; AMPK; AMP-activated protein kinase; ANGPT-L3; angiopoietin-like 3; BAT; brown adipose tissue; BDNF; brain derived neurotrophic factor; CREB; cAMP responsive element binding
Coordinate regulation by transcription factors and DNA methylation in the core promoter region of SIRT6 in bovine adipocytes
Keywords: عامل تنفسی هسته ای 1; SIRT6; Promoter; Transcriptional regulation; DNA methylation; Bovine; Adipocyte; qPCR; real-time quantitative; CEBPβ; CCAAT enhancer binding protein beta; PAX6; paired box 6; KLF2; Kruppel-like factor 2; CMYB; myb proto-oncogene protein; NRF1; nuclear re
Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control
Keywords: عامل تنفسی هسته ای 1; ALT; Alanine aminotransferase; Drp1; dynamin-related protein 1; EDTA; ethylenediaminetetraacetic acid; GDH; glutamate dehydrogenase; H&E; hematoxylin&eosin; HO-1; heme oxygenase-1; H/R; hypoxia/reoxygenation; IL; interleukin; I/R; ischemia/reperfusion; LP
Mitochondria as pharmacological targets in Down syndrome
Keywords: عامل تنفسی هسته ای 1; AD; Alzheimer's disease; AGO; Argonaute proteins; AMPK; AMP-activated protein kinase; ANTs; adenine nucleotide translocators; AK; adenylate kinase; APP; amyloid-β precursor protein; ASD; autism spectrum disorder; CAT; catalase; CNS; central nervous syste
Molecular drivers of mitochondrial membrane proliferation in response to cold acclimation in threespine stickleback
Keywords: عامل تنفسی هسته ای 1; AGPAT; 1-acylglycerol 3-phosphate acyltransferase; CDP-DAG; cytidine diphosphodiacylglycerol; CDS; cytidine diphosphodiacylglycerol synthase; CL; cardiolipin; DAG; diacylglycerol; EF-1α; elongation factor-1 alpha; G3P; glycerol 3-phosphate; GPAT; glycero
Mild palmitate treatment increases mitochondrial mass but does not affect EA.hy926 endothelial cells viability
Keywords: عامل تنفسی هسته ای 1; Endothelial cells; Inflammatory response; Mitochondrial mass; Palmitate; Reactive oxygen species; BSA; bovine serum albumin; Cu/Zn-SOD (SOD1); copper/zinc superoxide dismutase; eNOS; endothelial nitric oxide synthase; HUVEC; human umbilical vein endotheli
The protective effects of compatibility of Aconiti Lateralis Radix Praeparata and Zingiberis Rhizoma on rats with heart failure by enhancing mitochondrial biogenesis via Sirt1/PGC-1α pathway
Keywords: عامل تنفسی هسته ای 1; Sirt1; Sirtuin 1; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator 1α; NRF1; nuclear respiratory factor 1; NRF2; nuclear respiratory factor 2; CK; creatine kinase; LDH; lactate dehydrogenase; BNP; brain natriuretic peptide; cTnT; car
Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases
Keywords: عامل تنفسی هسته ای 1; ALP; alkaline phosphatase; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; BER; base excision repair; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CHIP; carboxyl terminus of Hsp70-interacting protein; CLL; chronic lympho
The plasticizer BBP selectively inhibits epigenetic regulator sirtuin during differentiation of C3H10T1/2 stem cell line
Keywords: عامل تنفسی هسته ای 1; BBP; Benzyl butyl phthalate; PGC1α; Peroxisome proliferator-activated receptor gamma coactivator 1 alpha; NRF1; Nuclear respiratory factor 1; NRF2; Nuclear respiratory factor 2; Tfam; Mitochondrial transcription factor A; FOXO1; Forkhead box protein O1;
Globular CTRP3 promotes mitochondrial biogenesis in cardiomyocytes through AMPK/PGC-1α pathway
Keywords: عامل تنفسی هسته ای 1; AMPK; AMP-activated protein kinase; AraA; adenine 9-β-d-arabinofuranoside; ATP-5β; ATP synthase 5β; Cyt B; cytochrome B; CTRP3; C1q/tumor necrosis factor-related protein-3; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; H/R; hypoxia-reoxy
Melatonin-mediated upregulation of Sirt3 attenuates sodium fluoride-induced hepatotoxicity by activating the MT1-PI3K/AKT-PGC-1α signaling pathway
Keywords: عامل تنفسی هسته ای 1; NaF; Sodium; ROS; Reactive oxygen species; O2â¢â; superoxide; GSH; Glutathione; MDA; Malondialdehyde; Bax; Bcl2-associated X protein; Bcl-2; B-cell CLL/lymphoma 2; GAPDH; Glyceraldehyde-3-Phosphate Dehydrogenase; COXIV; Cytochrome C Oxidase Subunit IV;
Dietary lipid concentration affects liver mitochondrial DNA copy number, gene expression and DNA methylation in large yellow croaker (Larimichthys crocea)
Keywords: عامل تنفسی هسته ای 1; ATPase 6; ATP synthase 6; COX; Cytochrome c oxidase; CS; Citrate synthase; CYTB; Cytochrome b; D-loop; Displacement loop; HIF1α; Hypoxia-inducible factor 1α; mtDNA; Mitochondrial DNA; MDA; Malondialdehyde; ND6; NADH dehydrogenase subunit 6; ND2; NADH de
Sensing and responding to energetic stress: The role of the AMPK-PGC1α-NRF1 axis in control of mitochondrial biogenesis in fish
Keywords: عامل تنفسی هسته ای 1; Muscle mitochondria; Evolution of energy metabolism; AMP-activated protein kinase; PPAR γ coactivator 1 α; Nuclear respiratory factor 1
Peroxisome proliferator-activated receptor-γ (PPARγ) agonist is neuroprotective and stimulates PGC-1α expression and CREB phosphorylation in human dopaminergic neurons
Keywords: عامل تنفسی هسته ای 1; PPARγ; PGC-1α; SIRT1; CREB; Dopaminergic neurons; Mitochondria; AC6; adenylyl cyclase 6; CRE; cAMP responsive element; CREB; cAMP responsive element-binding protein; FCCP; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; GW1929; N-(2-benzoylphenyl)
Research reportProtective effects of PGC-1α via the mitochondrial pathway in rat brains after intracerebral hemorrhage
Keywords: عامل تنفسی هسته ای 1; ICH; intracerebral hemorrhage; PGC-1α; Peroxisome proliferator activated receptor co-activator-1α; NRF1; Nuclear respiratory factor 1; Tfam; Mitochondrial transcription factor A; mtDNA; Mitochondrial DNA; UCP2; uncoupling protein 2; SOD2; superoxide dis
Epigallocatechin gallate and mitochondria-A story of life and death
Keywords: عامل تنفسی هسته ای 1; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; ALT; alanine aminotransferase; AMP; adenosine monophosphate; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; ATP; adenosine triphosphate; Bax; BCL2-Associated X Protein; Bc
α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects
Keywords: عامل تنفسی هسته ای 1; α-Lip; α-Lipoic acid; LDH; lactate dehydrogenase; mtDNA; mitochondrial DNA; Sirt1; Sirtuin 1; PGC-1α; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; Nrf1; nuclear respiratory factor 1; Tfam; mitochondrial transcription factor; C
BPA-induced DNA hypermethylation of the master mitochondrial gene PGC-1α contributes to cardiomyopathy in male rats
Keywords: عامل تنفسی هسته ای 1; ATP5E; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit; ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; BPA; bisphenol A; CpG; cytosine phosphate guanine; DNMT3A; DNA methyltransferase 3A; DNMT3B; DNA me
The plasticizer BBP selectively inhibits epigenetic regulator sirtuins
Keywords: عامل تنفسی هسته ای 1; BBP; benzyl butyl phthalate; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; NRF-1; nuclear respiratory factor 1; NRF-2; nuclear respiratory factor 2; Sirtuins; Benzyl butyl phthalate (BBP); Metabolic syndrome; Mitochondria;
Recombinant human augmenter of liver regeneration protects hepatocyte mitochondrial DNA in rats with obstructive jaundice
Keywords: عامل تنفسی هسته ای 1; Obstructive jaundice; Augmenter of liver regeneration; Mitochondrial DNA; Mitochondrial transcription factor A; Nuclear respiratory factor 1; Hepatic function
Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells
Keywords: عامل تنفسی هسته ای 1; Sirtuins; Pyrroloquinoline quinone; Metabolic syndrome; Mitochondria; Aging; Mitochondrial biogenesis regulators; CR; caloric restriction; mRNA; messenger RNA; NAMPT; nicotinamide phosphoribosyltransferase; NRF-1; nuclear respiratory factor 1; NRF-2; nucl
Redox modulation of mitochondriogenesis in exercise. Does antioxidant supplementation blunt the benefits of exercise training?
Keywords: عامل تنفسی هسته ای 1; Akt; protein kinase B; AMPK; 5â²-AMP-activated protein kinase; AP-1; activator protein 1; COX IV; cytochrome c oxidase; CuZnSOD; copper/zinc superoxide dismutase; DMSO; dimethyl sulfoxide; eNOS; endothelial nitric oxide synthase; ERK; extracellular signa
Vitamin C and E supplementation prevents some of the cellular adaptations to endurance-training in humans
Keywords: عامل تنفسی هسته ای 1; ROS; reactive oxygen species; COX IV; cytochrome c oxidase subunit 4; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator 1α; CS; citrate synthase; VO2peak; peak oxygen consumption; Wmax; maximal power output; Wfinal; final completed wo
Delphinidin inhibits VEGF induced-mitochondrial biogenesis and Akt activation in endothelial cells
Keywords: عامل تنفسی هسته ای 1; ER; estrogen receptor; ERRα; estrogen-related receptor α; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; Delph; delphinidin; HUVECs; human umbilical vein endothelial cells; mtDNA; mitochondrial DNA; ND5; NADH dehydrogenase subunit 5; NO; n
Inadequate mito-biogenesis in primary dermal fibroblasts from old humans is associated with impairment of PGC1A-independent stimulation
Keywords: عامل تنفسی هسته ای 1; 12S; mitochondrial rRNA; AICAR; aminoimidazole-4-carboxamide riboside, an adenosine analogue stimulating AMPK; AMPK; catalytic α1/2-subunit of AMP dependent protein kinase; pAMPK; AMPK phosphorylated at serine 172 of the α-subunit; AU; arbitrary units;
Regulation of the biogenesis of OXPHOS complexes in cell transition from replicating to quiescent state
Keywords: عامل تنفسی هسته ای 1; AKAP; A-kinase anchor proteins; Akt; protein kinase B; CREB; cAMP response element-binding protein; HT; hydroxytyrosol; NHDF-neo; neonatal normal human dermal fibroblasts; NRF1; nuclear respiratory factor 1; OXPHOS; oxidative phosphorylation system; PGC-1
Glycogen synthase kinase-3 (GSK3) controls deoxyglucose-induced mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells
Keywords: عامل تنفسی هسته ای 1; AMPK; AMP-activated protein kinase; mtCOXII; Mitochondrial cytochrome c oxidase subunit II; mtCOXIII; Mitochondrial cytochrome c oxidase subunit III; mtCYTB; Mitochondrial cytochrome b; 2-DG; 2-Deoxyglucose; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase
Metabolic and transcriptional responses of gilthead sea bream (Sparus aurata L.) to environmental stress: New insights in fish mitochondrial phenotyping
Keywords: عامل تنفسی هسته ای 1; ACAA2; 3-ketoacyl-CoA thiolase, mitochondrial; AIFM1; apoptosis-related protein 1; AIFM3; apoptosis-related protein 3; ANOVA; analysis of variance; BAX; apoptosis regulator BAX; BCL2; apoptosis regulator Bcl-2; BCLX; Bcl-2-like protein 1; CAT; catalase; C
Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: An overview of Down syndrome, autism, Fragile X and Rett syndrome
Keywords: عامل تنفسی هسته ای 1; Intellectual disability; Mitochondria; Mitochondrial dysfunction; Oxidative phosphorylation; Neurogenesis; Neuroplasticity; Down syndrome; Rett syndrome; Autism; Fragile X; Oxidative stress; Drug development; Epigallocatechine-3-gallate; ANT; adenine nucl
ATF3 plays a role in adipocyte hypoxia-mediated mitochondria dysfunction in obesity
Keywords: عامل تنفسی هسته ای 1; ATF3; activating transcription factor 3; COX1; cytochrome C oxidase 1; HIF-1α; hypoxia inducible factor-1; HFD; high fat diet; MTT; 3-(4, 5 dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide; NRF-1; nuclear respiratory factor 1; SOD; superoxide dism
Wild bitter gourd increased metabolic rate and up-regulated genes related to mitochondria biogenesis and UCP-1 in mice
Keywords: عامل تنفسی هسته ای 1; ACADL1; acyl-Coenzyme A dehydrogenase, long-chain; ACSL3; acyl-CoA synthetase long-chain family member 3; AMPK; AMP activated protein kinase; BAT; brown adipose tissue; BG; bitter gourd; BGP; bitter gourd powder; CLN; 9c, 11t, 13t-conjugated linolenic aci
Punctum on two different transcription factors regulated by PGC-1α: Nuclear factor erythroid-derived 2-like 2 and nuclear respiratory factor 2
Keywords: عامل تنفسی هسته ای 1; γGCS; gamma-glutamylcysteine synthetase; ARE; antioxidant responsive element; BAT; brown adipose tissue; CNC; Cap 'n' collar; COX; cytochrome c oxidase; CR; calorie restriction; CREB; cAMP response element-binding protein; ERRs; Estrogen-related rece