COP9 signalosome function in the DDR
Keywords: تعمیر مجدد نوکلئوتیدی; COP9 signalosome; Nedd8; Cullin-RING ubiquitin ligase; Nucleotide excision repair; Checkpoint control;
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A genome-wide shRNA screen for new OxPhos related genes
Keywords: تعمیر مجدد نوکلئوتیدی; ETC; electron transport chain; OxPhos; oxidative phosphorylation; mtDNA; mitochondrial DNA; RNAi; RNA interference; siRNA; silencing RNA; shRNA; short hairpin RNA; UPS; ubiquitin proteasome system; NER; nucleotide excision repair; RRM; RNA recognition mot
Modulation of the processive abasic site lyase activity of a pyrimidine dimer glycosylase
Keywords: تعمیر مجدد نوکلئوتیدی; AP; apurinic/apyrimidinic; BER; base excision repair; CPDs; cyclobutane pyrimidine dimers; NER; nucleotide excision repair; pdg; pyrimidine dimer DNA glycosylase/AP site lyase; UV; ultraviolet; Abasic sites; Base excision repair; Structure-function; Pro
DNA repair and replication influence the number of mutations per adduct of polycyclic aromatic hydrocarbons in mammalian cells
Keywords: تعمیر مجدد نوکلئوتیدی; PAH; polycyclic aromatic hydrocarbons; PAH-DE; polycyclic aromatic hydrocarbon diolepoxide; BPDE; (+)-anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo-[a]pyrene; DBADE; (±)-anti-3,4-dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrodibenz-[a,h]anthracene; DBPD
Role of Interaction of XPF with RPA in Nucleotide Excision Repair
Keywords: تعمیر مجدد نوکلئوتیدی; NER, nucleotide excision repair; dsDNA, double-stranded DNA; NLS, nuclear localization signal; EDTA, ethylenediaminetetraacetic acid; CPV, cell pellet volume; 6-4 PP, 6-4 photoproductXPF–ERCC1; RPA; nucleotide excision repair; subcellular localization; pr
The response of mammalian cells to UV-light reveals Rad54-dependent and independent pathways of homologous recombination
Keywords: تعمیر مجدد نوکلئوتیدی; Homologous recombination; Nucleotide excision repair; Replication fork stalling; Translesion synthesis; UV-light
Clustered DNA lesion repair in eukaryotes: Relevance to mutagenesis and cell survival
Keywords: تعمیر مجدد نوکلئوتیدی; DSB; double strand break; MDS; multiply damaged sites; SSB; single strand break; LET; linear energy transfer; BER; base excision repair; NER; nucleotide excision repair; HR; homologous recombination; NHEJ; non-homologous end-joining; PRR; post-replication
Aging, longevity and health
Keywords: تعمیر مجدد نوکلئوتیدی; AD; Alzheimer's disease; BMI; body mass index; BER; base excision repair; CS; Cockayne syndrome; HD; Huntington's disease; IARU; International Alliance of Research Universities; NER; nucleotide excision repair; NUS; National University of Singapore; PWD;
The role of XPC: Implications in cancer and oxidative DNA damage
Keywords: تعمیر مجدد نوکلئوتیدی; Xpc; Nucleotide excision repair; Mutation; Cancer; Oxidative DNA damage
Dynamics of mammalian NER proteins
Keywords: تعمیر مجدد نوکلئوتیدی; Live cell imaging; Nucleotide excision repair; Photo-bleaching; Spatio-temporal NER; DNA damage response
Role of the insertion domain and the zinc-finger motif of Escherichia coli UvrA in damage recognition and ATP hydrolysis
Keywords: تعمیر مجدد نوکلئوتیدی; UvrABC; Nucleotide excision repair
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase
Keywords: تعمیر مجدد نوکلئوتیدی; Nucleotide excision repair; Helicase; TFIIH assembly; Structure; Human disease
Scanning the DNA for damage by the nucleotide excision repair machinery
Keywords: تعمیر مجدد نوکلئوتیدی; Nucleotide excision repair; XPC; XPB; XPD; UvrA; UvrB; Damage recognition
HMGNs, DNA repair and cancer
Keywords: تعمیر مجدد نوکلئوتیدی; HMGN proteins; Nucleotide excision repair; Transcription coupled repair; Double-strand breaks; DNA damage response; Histone H1
Transcription-coupled nucleotide excision repair of a gene transcribed by bacteriophage T7 RNA polymerase in Escherichia coli
Keywords: تعمیر مجدد نوکلئوتیدی; NER; nucleotide excision repair; TC-NER; transcription-coupled nucleotide excision repair; GG-NER; global genomic nucleotide excision repair; IPTG; isopropyl-β-d-thiogalactopyranoside; ONPG; o-nitrophenyl-β-d-galactopyranoside; Transcription-coupled nuc
Benzene-derived N2-(4-hydroxyphenyl)-deoxyguanosine adduct: UvrABC incision and its conformation in DNA
Keywords: تعمیر مجدد نوکلئوتیدی; HQ; hydroquinone; p-BQ; p-benzoquinone; N2-4-HOPh-dG; N2-(4-hydroxyphenyl)-2'-deoxyguanosine; AP; apurinic/apyrimidinic; UvrABC; E. coli UvrABC complex; NER; nucleotide excision repair; BER; base excision repair; Exo III; exonuclease III; Endo IV; endon
Screening of nitrosative stress resistance genes in Coxiella burnetii: Involvement of nucleotide excision repair
Keywords: تعمیر مجدد نوکلئوتیدی; Nitric oxide; Reactive nitrogen intermediates; Nitrosative stress; uvrB; Nucleotide excision repair; DNA repair
HTLV-1 Tax: Linking transformation, DNA damage and apoptotic T-cell death
Keywords: تعمیر مجدد نوکلئوتیدی; AP-1; activator protein 1; APC; anaphase promoting complex; ATL; adult T-cell leukemia; ATM kinase; ataxia telangiectasia mutated kinase; BES; base excision repair; Chk1; checkpoint kinase 1; Chk2; checkpoint kinase 2; CREB; cyclic AMP response element-bi
Differential survival of Escherichia coli uvrA, uvrB, and uvrC mutants to psoralen plus UV-A (PUVA): Evidence for uncoupled action of nucleotide excision repair to process DNA adducts
Keywords: تعمیر مجدد نوکلئوتیدی; PUVA; Nucleotide excision repair; Escherichia coli; UvrB
Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease
Keywords: تعمیر مجدد نوکلئوتیدی; Colonic obstruction; DNA damage; Enteric nervous system; Melanocytes; Nucleotide excision repair
Interplay of DNA repair, homologous recombination, and DNA polymerases in resistance to the DNA damaging agent 4-nitroquinoline-1-oxide in Escherichia coli
Keywords: تعمیر مجدد نوکلئوتیدی; Recombination; Escherichia coli; DNA repair; DNA damage; Nucleotide excision repair; recG; dinB; ruvABC; Nitroquinoline-oxide;
Effect of the anti-neoplastic drug doxorubicin on XPD-mutated DNA repair-deficient human cells
Keywords: تعمیر مجدد نوکلئوتیدی; Nucleotide excision repair; Doxorubicin; Xeroderma pigmentosum group D; Topoisomerase II; Cancer
XPC Epigenetic Silence Coupled With p53 Alteration Has a Significant Impact on Bladder Cancer Outcome
Keywords: تعمیر مجدد نوکلئوتیدی; urinary bladder; carcinoma; urothelium; XPC protein, human; genes, p53; BSP; PCR based bisulfite genomic sequencing; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MSP; methylation specific PCR; NER; nucleotide excision repair; PCR; polymerase chain rea
Regulation of damage recognition in mammalian global genomic nucleotide excision repair
Keywords: تعمیر مجدد نوکلئوتیدی; Nucleotide excision repair; Xeroderma pigmentosum; XPC; UV-DDB; Ubiquitination
The NER proteins XPC and CSB, but not ERCC1, regulate the sensitivity to the novel DNA binder S23906: Implications for recognition and repair of antitumor alkylators
Keywords: تعمیر مجدد نوکلئوتیدی; Nucleotide excision repair; S23906; Monofunctional alkylators; XPC; ERCC1;
Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure
Keywords: تعمیر مجدد نوکلئوتیدی; eEXT, optical extinction; UVC, ultraviolet C radiation; NER, nucleotide excision repairCaenorhabditis elegans; DNA damage response; Nucleotide excision repair; Global gene expression; Gene–environment interaction
Role of the two ATPase domains of Escherichia coli UvrA in binding non-bulky DNA lesions and interaction with UvrB
Keywords: تعمیر مجدد نوکلئوتیدی; UvrABC; ATPase; Nucleotide excision repair
Wot the ‘L—Does MutL do?
Keywords: تعمیر مجدد نوکلئوتیدی; MutL; MutS; Mismatch repair; Nucleotide excision repair; Base excision repair; Somatic hypermutation; Apoptosis
Roles of Werner syndrome protein in protection of genome integrity
Keywords: تعمیر مجدد نوکلئوتیدی; γ-H2AX; phosphorylated histone H2AX; 4-NQO; 4-nitroquinoline 1-oxide; 5-OHdC; 5-hydroxycytidine; 5-OHU; 5-hydroxyuracil; 8-oxodA; 8-oxoadenine; 8-oxodG; 8-oxoguanine; ALT; alternative lengthening of telomeres; APE1; apurinic/apyrimidinic endonuclease 1;
Assays for chromatin remodeling during nucleotide excision repair in Saccharomyces cerevisiae
Keywords: تعمیر مجدد نوکلئوتیدی; Chromatin; Nucleotide excision repair; Methods; Yeast; SWI/SNF
Accumulation of (5′S)-8,5′-cyclo-2′-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice
Keywords: تعمیر مجدد نوکلئوتیدی; Cockayne syndrome; 8,5′-Cyclopurine-2′-deoxynucleosides; Helix-distorting lesion; Hydroxyl radical; Intramolecular cyclization; Mass spectrometry; Nucleotide excision repair; Oxidatively induced DNA damage
Correlations and co-localizations of Hsp70 with XPA, XPG in human bronchial epithelia cells exposed to benzo[a]pyrene
Keywords: تعمیر مجدد نوکلئوتیدی; Benzo[a]pyrene; Heat shock protein 70; Nucleotide excision repair; Human bronchial epithelia cells;
Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells
Keywords: تعمیر مجدد نوکلئوتیدی; Aryl hydrocarbon receptor; Nucleotide excision repair; Benzo[a]pyrene; 2,3,7,8-Tetrachlorodibenzo-p-dioxin; cis-Platin; p53
17α-Ethinylestradiol hinders nucleotide excision repair in zebrafish liver cells
Keywords: تعمیر مجدد نوکلئوتیدی; Ethinylestradiol; Zebrafish; Nucleotide excision repair; XPA; XPC; ICI 182,780
Interaction between the mismatch repair and nucleotide excision repair pathways in the prevention of 5-azacytidine-induced CG-to-GC mutations in Escherichia coli
Keywords: تعمیر مجدد نوکلئوتیدی; 5-Azacytidine; Mismatch repair; Nucleotide excision repair; Mutagenesis; Bacterial two-hybrid assay
Relationship between methylation status of ERCC1 promoter and radiosensitivity in glioma cell lines
Keywords: تعمیر مجدد نوکلئوتیدی; Glioma; Methylation; Epigenetics; Radiosensitivity; ERCC1; Excision repair cross complementing protein 1; ERCC2; Excision repair cross complementing protein 2; XPF; Xeroderma pigmentosum complementation group F; NER; Nucleotide excision repair; SF2; Survi
Wastewater treatment effluent alters nucleotide excision repair in zebrafish (Danio rerio)
Keywords: تعمیر مجدد نوکلئوتیدی; Wastewater; Zebrafish; Nucleotide excision repair; Vitellogenin; CYP1A1
In vivo treatment with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces organ-specific alterations in in vitro repair of DNA pyridyloxobutylation
Keywords: تعمیر مجدد نوکلئوتیدی; NNK; 4-methylnitrosamino-1-(3-pyridyl)-1-butanone; NNKOAc; 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone; POB; 4-(3-pyridyl)-4-oxobut-1-yl; NER; nucleotide excision repair; GGR; global genome repair; NNK; Pyridyloxobutylation; Nucleotide excision
The alkyltransferase-like ybaZ gene product enhances nucleotide excision repair of O6-alkylguanine adducts in E. coli
Keywords: تعمیر مجدد نوکلئوتیدی; Alkyltransferases; Cross-talk between repair pathways; Nucleotide excision repair; O6-alkylguanine adducts;
Tilting at windmills? The nucleotide excision repair of chromosomal DNA
Keywords: تعمیر مجدد نوکلئوتیدی; DNA damage; Nucleotide excision repair; Chromatin; S. cerevisiae
Human HMGB1 directly facilitates interactions between nucleotide excision repair proteins on triplex-directed psoralen interstrand crosslinks
Keywords: تعمیر مجدد نوکلئوتیدی; HMGB1; Nucleotide excision repair; XPC-RAD23B; RPA; Interstrand crosslink
Topical thymidine dinucleotide application protects against UVB-induced skin cancer in mice with DNA repair gene (Ercc1)-deficient skin
Keywords: تعمیر مجدد نوکلئوتیدی; DNA damage; DNA repair; Nucleotide excision repair; Ultraviolet irradiation
The anti-apoptotic role for p53 following exposure to ultraviolet light does not involve DDB2
Keywords: تعمیر مجدد نوکلئوتیدی; Apoptosis; DDB2; Nucleotide excision repair; p53; Ultraviolet light; Xeroderma pigmentosum group E
Regulation of DNA damage response pathways by the cullin-RING ubiquitin ligases
Keywords: تعمیر مجدد نوکلئوتیدی; Ubiquitin; Cullin-RING ligase; Nucleotide excision repair
Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells
Keywords: تعمیر مجدد نوکلئوتیدی; Mismatch repair; Nucleotide excision repair; Trinucleotide repeat; Transcription; Repeat instability
The RAD9-dependent gene trans-activation is required for excision repair of active genes but not for repair of non-transcribed DNA
Keywords: تعمیر مجدد نوکلئوتیدی; Nucleotide excision repair; RAD9; Global genomic repair; Transcription-coupled repair
UV-DDB-dependent regulation of nucleotide excision repair kinetics in living cells
Keywords: تعمیر مجدد نوکلئوتیدی; Nucleotide excision repair; Dynamics; XPC; UV-DDB;
The unstructured C-terminal extension of UvrD interacts with UvrB, but is dispensable for nucleotide excision repair
Keywords: تعمیر مجدد نوکلئوتیدی; Nucleotide excision repair; Helicase recruitment; Protein-protein interactions;
Yeast Elc1 plays an important role in global genomic repair but not in transcription coupled repair
Keywords: تعمیر مجدد نوکلئوتیدی; NER; nucleotide excision repair; TCR; transcription coupled repair; GGR; global genomic repair; Pol II; RNA polymerase II; Elc1; Nucleotide excision repair; Rad7; Rad16; Rad26; Rpb9; Saccharomyces cerevisiae;
The ubiquitin receptor Rad23: At the crossroads of nucleotide excision repair and proteasomal degradation
Keywords: تعمیر مجدد نوکلئوتیدی; CS; Cockayne syndrome; DUBs; deubiquitylation enzymes; ER; endoplasmic reticulum; ERAD; ER-associated degradation; GGR; global genomic NER; hHR23; human homologue Rad23; mHR23; murine homologue Rad23; NER; nucleotide excision repair; TFIIH; transcription