Keywords: grandpa1; ATP; adenosine triphosphate; BES; biolimus-eluting stents; BMS; bare-metal stent; cGMP; cyclic guanosine monophosphate; DES; drug-eluting stents; DRP 1; dynamin-related protein 1; EES; everolimus eluting stent; eNOS; endothelial NOS; FAD; flavin adenine d
مقالات ISI grandpa1 (ترجمه نشده)
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Keywords: grandpa1; MAP1LC3; microtubule-associated protein 1 light chain 3; LAMP1; lysosomes associated membrane protein 1; ROS; reactive oxygen species; EGCG; epigallocatechin gallate; CCCP; carbonyl cyanide 3-chlorophenylhydrazone; VDAC1; voltage-dependent anion-selective
Keywords: grandpa1; ad-virDRP1K38A; dominant-negative DRP1; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; ATP5; ATP synthase subunit 5; DAG; diacylglycerol; DRP1; dynamin related protein 1; ER; endoplasmic reticulum; FAO; fatty acid beta-oxidation; JC-1; 5,5â²,6,6â
Keywords: grandpa1; APL; allosterically potentiating ligand; AD; Alzheimer's disease; Aβ; amyloid-β; ALS; amyotrophic lateral sclerosis; BCCAs; bilateral common carotid arteries stenosis; CTX; cerebral cortex; DAB; diaminobenzidine; Drp1; dynamin-related protein 1; ECTX;
Keywords: grandpa1; Mitochondria; Cristae ultrastructure; OPA1; MICOS; ATP synthase dimers;
Keywords: grandpa1; 8OH-G; 8-hydroxyguanine; CK; Creatine kinase, 2; CS; citrate synthase; DNMT1-3A-3B; DNA methyltransferase 1, 3A, 3B; DRP1; dynamin-related protein 1; p-DRP1; dynamin-phosphorylated related protein 1; ETC; electron transport chain; HO-1; heme oxygenase;
Keywords: grandpa1; WT; wild-type; KO; knockout; tau-/-; homozygous tau KO; mPTP; Mitochondrial permeability transition pore; AD; Alzheimer's disease; GR; Glucocorticoid Receptor; HO; heme oxygenase; GCS; γ-glutamine cysteine synthase; ROS; reactive oxygen species; Mfn1; Mi
Keywords: grandpa1; PRR; pattern recognition receptor; PAMP; pathogen-associated molecular pattern; DAMP; danger-associated molecular pattern; NLRP3; NOD-, LRR- and pyrin domain-containing 3; TLR; toll-like receptor; CLR; C-type lectin receptor; NLR; NOD-like receptor; RIG-I
Keywords: grandpa1; MIA; mitochondrial intermembrane space import and assembly machinery; MICOS; mitochondrial contact site and cristae organizing system; MicX; Mic protein of X kDa (subunit of MICOS); OPA1; optic atrophy 1; SAM; sorting and assembly machinery; TIM23; preseq
Keywords: grandpa1; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; CHOP; C/EBP homologous protein; DRP1; dynamin-related protein 1; FIS1; fission protein 1; GRP78; 78Â kDa glucose-regulat
Keywords: grandpa1; Mitochondrial encephalopathy; Ndufs4 knockout mice; Rapamycin; Mitochondria; Mitochondrial diseases; ATP5D; ATP synthase H+ transporting mitochondrial F1 complex delta subunit; Cox1; cytochrome c oxidase I; Cox2; cytochrome c oxidase subunit 2; Cox15; Cyt
Keywords: grandpa1; ALCAR; Acetyl-l-carnitine; mtDNA; mitochondrial DNA; nDNA; nuclear DNA; CS; citrate synthase; PGC-1α; peroxisome proliferator-activated receptor γ [PPARγ] coactivator-1α; PGC-1β; peroxisome proliferator-activated receptor γ [PPARγ] coactivator-1 β
Keywords: grandpa1; asthma; COPD; metabolism; oxidative stress; remodeling; ASM; airway smooth muscle; ATP; adenosine triphosphate; CS; cigarette smoke; DAMP; damage-associated molecular pattern; Drp1; dynamin-related protein 1; ER; endoplasmic reticulum; Fis1; fission 1; Mf
Keywords: grandpa1; OM; outer membrane; IM; inner membrane; IBM; inner boundary membrane; EM; electron microscopy; ETC; electron transport chain; MICOS; mitochondrial contact site and cristae organizing system; PE; phosphatidylethanolamine; PS; phosphatidylserine; Opa1; opti
Keywords: grandpa1; Brain ischemia; Reperfusion; Mitochondrial dynamics; Opa1;
Keywords: grandpa1; DA; dopaminergic; MPP+; 1-methyl-4-phenylpyridinium; PD; Parkinson's disease; TH; tyrosine hydroxylase; Drosophila; Mitochondria; drp1; opa1; Parkinson;
Keywords: grandpa1; Auditory nerve disease; Auditory neuropathy; Auditory neuropathy spectrum disorders; DPOAE; ABR; OTOF; OPA1;
Keywords: grandpa1; Mitochondria; Mitochondrial fission; Mitochondrial fusion; DRP1; OPA1; MFN1; MFN2; GDAP1; Neurodegeneration; Charcot-Marie-Tooth disease; Dominant Optic Atrophy; Neuronal maturation; Neuronal plasticity; Synapse; Dendrite; Axon;
Keywords: grandpa1; Ambra1; activating molecule in Beclin1-regulated autophagy 1; Atg; autophagy-related protein; BDNF; brain-derived neurotrophic factor; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; CREB; cAMP response element-binding; DIC; dynein intermediate
Keywords: grandpa1; ANOVA; analysis of variance; BITC; benzyl isothiocyanate; DAPI; 4â²,6-diamidino-2-phenylindole; DKO; mouse embryonic fibroblasts isolated from Bak and Bax double knockout mice; DMSO; dimethyl sulfoxide; Drp1; dynamin related protein 1; Fis1; mitochondria
Keywords: grandpa1; Drp1; Dynamin-related protein1; GSK3β; Glucose synthase kinase 3 beta; CDK5; Cyclin dependent kinase 5; miRNA; micro ribonucleic acid; NMDAR; N-methyl-D-aspartate receptor; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; AD; Alzhei
Keywords: grandpa1; AMPK; AMP-activated protein kinase; BM; bone marrow; CAT; catalase; Complex I; NADH-coenzyme Q oxidoreductase; Complex II; succinate-coenzyme Q oxidoreductase; Complex III; ubiquinol-cytochrome c oxidoreductase; COX; cytochrome c oxidase; Complex V; FoF1A
Keywords: grandpa1; Îp; proton motive force established on inner mitochondrial membrane; ÎÏ; electrical membrane potential established on inner mitochondrial membrane; COX4.1; cytochrome c oxidase subunit 4 isoform 1; ERK; extracellular signal-regulated kinase; FA; fatty
Keywords: grandpa1; Mitochondrial fusion; Mitochondrial fission; MFN1; MFN2; Drp1; OPA1; Chemical compounds studied in this article; mdivi-1 (PubChem CID:3825829); Calcineurin (PubChem CID:16219117); Dynasore (PubChem CID:5717066); Phenylephrine (PubChem CID:6041);
Keywords: grandpa1; AD; Alzheimer's disease; ANOVA; analysis of variance; EDTA; ethylenediaminetetraacetic acid; HD; Huntington's disease; HDAC; histone deacetylase; OPA1; optic atrophy type 1; PD; Parkinson's disease; ROS; reactive oxygen species; sulforaphane; iron;
Keywords: grandpa1; ACLY; ATP citrate lyase; AKT; protein kinase B; ATP; adenosine triphosphate; ANT; adenine nucleotide translocator; AMPK; AMP-activated protein kinase; COX; cytochrome c oxidase; EGFR; epidermal growth factor receptor; ERRα; estrogen-related receptor alph
Keywords: grandpa1; AICAR; 5â²aminoimidazole-4-carboxyamide-ribonucleoside; AD; Alzheimer's disease; ATF-2; activating transcription factor-2; AMPK; AMP-activated protein kinase; Bnip3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BnipL/Nix; BCL2/adenovirus E1B 19Â
Keywords: grandpa1; Mitochondria; Mitochondrial diseases; Neurodegenerative disorders; Pharmacological neuroprotection; Mitochondrie; Maladies mitochondriales; Maladies neurodégénératives; Neuroprotection pharmacologique; AD; Alzheimer's disease; AICAR; 5-aminoimidazole-4
Keywords: grandpa1; CYP11A1; cytochrome P450, family 11, subfamily A, polypeptide 1; PKA; cyclic-AMP-dependent protein kinase; ACTH; adrenocorticotropin hormone; LH; luteinizing hormone; IMM; inner mitochondrial membrane; P5; pregnenolone; ER; the endoplasmic reticulum; OMM;
Keywords: grandpa1; Rhomboid protease; Parl; PINK1; Opa1; Hax1; Mitophagy;
Keywords: grandpa1; AD; Alzheimer's disease; CR; caloric restriction; DRG; dorsal root ganglion; Drp1; dynamin-related protein 1; HAT; histone acetyltransferase; HD; Huntington's disease; HDAC; histone deacetylase; Hsp90; heat shock protein 90; KAT; lysine acetyltransferases
SIRT3-mediated cardiac remodeling/repair following myocardial infarction
Keywords: grandpa1; MI; myocardial infarction; HIF; hypoxia inducible factor-1α; SOD2; superoxide dismutase; FOXO3A; forkhead box O3a; OPA1; optic atrophy 1; MMPs; matrix metalloproteinases; TGF-β; transforming growth factor-β; PARP-1; poly (ADP ribose)- polymerase 1; VEG
Eight human OPA1 isoforms, long and short: What are they for?
Keywords: grandpa1; OPA1; Long and short OPA1 forms; Mitochondrial network dynamics; Cristae; mtDNA; Energetics;
Different mitochondrial fragmentation after irradiation with X-rays and carbon ions in HeLa cells and its influence on cellular apoptosis
Keywords: grandpa1; Mitochondrial dynamics; Different quality radiations; Release of cytochrome c; Apoptosis; Radiosensitivity; LET; linear energy transfer; RBE; relative biological effectiveness; Mfn1; mitofusin1; Mfn2; mitofusin 2; OPA1; optic atrophy 1; Drp1; Dynamin-rela
The expression pattern and potential functions of PHB in the spermiogenesis of Phascolosoma esculenta
Keywords: grandpa1; PHB; prohibitin; Pe-PHB; Phascolosoma esculenta PHB protein; PBS; phosphate buffered saline; qPCR; real-time quantitative PCR; HE; hematoxylin-eosin; FITC; fluorescein isothiocyanate; ORF; open reading frame; FISH; fluorescence in situ hybridization; IF
Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models
Keywords: grandpa1; OPA1 mutations; Dominant Optic Atrophy (DOA); OPA1; Mitochondrial network; mtDNA; Mitochondrial functions;
Protective effect of mitochondrial-targeted antioxidant MitoQ against iron ion 56Fe radiation induced brain injury in mice
Keywords: grandpa1; IR; iron ion 56Fe radiation; ROS; reactive oxygen species; cyto c; cytochrome c; Mfn2; mitofusin2; Drp1; dynamic-like protein; OPA1; andoptic atrophy gene1; ATP; adenosine triphosphate; mtDNA; mitochondrial DNA; nDNA; nuclear DNA; ADP; adenosine 5â²-diph
Relationship between OPA1 and cardiolipin in mitochondrial inner-membrane fusion
Keywords: grandpa1; OPA1; optic atrophy 1; IM; inner membrane; OM; outer membrane; CL; cardiolipin; KO; knockout; Mfns; mitofusins; MEF; mouse embryonic fibroblast; mtDNA; mitochondrial DNA; Drp1; dynamin-related protein 1; Mff; mitochondrial fission factor; MiD49/MIEF2; mit
Mitochondria-associated membranes (MAMs): An emerging platform connecting energy and immune sensing to metabolic flexibility
Keywords: grandpa1; Organelle communication; Mitochondria-associated membranes; Nutrients; Microbiome; Innate immunity; Insulin sensitivity; Metabolic diseases; Ca2+; calcium; CLRs; C-type lectin receptors; CypD; cyclophilin D; DAMPs; Danger-Associated Molecular patterns; ER
Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control
Keywords: grandpa1; ALT; Alanine aminotransferase; Drp1; dynamin-related protein 1; EDTA; ethylenediaminetetraacetic acid; GDH; glutamate dehydrogenase; H&E; hematoxylin&eosin; HO-1; heme oxygenase-1; H/R; hypoxia/reoxygenation; IL; interleukin; I/R; ischemia/reperfusion; LP
Mitochondria as pharmacological targets in Down syndrome
Keywords: grandpa1; AD; Alzheimer's disease; AGO; Argonaute proteins; AMPK; AMP-activated protein kinase; ANTs; adenine nucleotide translocators; AK; adenylate kinase; APP; amyloid-β precursor protein; ASD; autism spectrum disorder; CAT; catalase; CNS; central nervous syste
ALS-associated mutation SOD1G93A leads to abnormal mitochondrial dynamics in osteocytes
Keywords: grandpa1; ALS; Amyotrophic lateral sclerosis; Drp1; dynamin-related protein 1; G93A; an ALS mouse model with overexpression of ALS-associated mutation SOD1G93A; GFP; green fluorescence protein; OPA1; optic atrophy protein 1; SOD1; superoxide dismutase 1; SOD1G93A;
FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission
Keywords: grandpa1; AGEs; advanced glycation end products; Drp1; dynamin-relatedprotein-1; ECs; endothelial cells; FOXO1; forkhead box O1; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HUVECs; human umbilical vein endothelial cells; HG; high glucose concentration; mtROS;
Regulation of mitochondrial dynamics by DISC1, a putative risk factor for major mental illness
Keywords: grandpa1; Mitochondrial dynamics; Mitochondrial trafficking; DISC1; NDE1; TRAK1/2; GSK3β; DISC1; Disrupted in Schizophrenia 1; DISC1FP1; DISRUPTED in Schizophrenia 1 Fusion Partner 1; FEZ1; Fasciculation and Elongation Protein Zeta 1; GABAA; Gamma-Aminobutyric Aci
Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice
Keywords: grandpa1; ALT; Alanine aminotransferase; ActD; Actinomycin D; CYP; Cytochrome P450; CQ; Chloroquine; Drp1; Dynamin-related protein 1; DHPAs; Dehydropyrrolizidine alkaloids; DHR; dehydroretronecine; EM; Electron microscopy; GSH; Glutathione; GAPDH; Glyceradehyde-3-p
Hydrogen sulfide-producing cystathionine γ-lyase is critical in the progression of kidney fibrosis
Keywords: grandpa1; CSE; Cystathionine γ-lyase; H2S; Hydrogen sulfide; GSH; Glutathione; CKD; Chronic kidney disease; UUO; Unilateral ureteral obstruction; P5P; Pyridoxal-5â²-phosphate; CBS; Cystathionine β-synthase; 3-MST; 3-mercaptopyruvate sulfurtransferase; Nrf2; NFâ
Research PaperAge-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression
Keywords: grandpa1; CMT; Charcot-Marie-Tooth; DBA; DBA/2J; DOA; dominant optic atrophy; D2G; DBA/2JGpnmb +;  IOP; intraocular pressure; Mfn1; mitofusin 1; Mfn2; mitofusin 2; NICIF; nanoimmuno capillary isoelectric focusing; NP; NanoPro; ON; optic nerve; Opa1; optic atrophy
CDK5 inhibitors prevent astroglial apoptosis and reactive astrogliosis by regulating PKA and DRP1 phosphorylations in the rat hippocampus
Keywords: grandpa1; SE; status epilepticus; MFN1; mitofusin 1; MFN2; mitofusin 2; OPA1; optic atrophy 1; DRP1; dynamin-related protein 1; Fis-1; fission related protein-1; MFF; mitochondrial fission factor; CDK5; cyclin-dependent kinase 5; PKA; protein kinase A; AIF; apoptot
An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle
Keywords: grandpa1; CAT; catalase; COX; cytochrome c oxidase; DJ7; Parkinson 7; DNM1L; dynamin-1-like protein; FIS1; mitochondrial fission protein 1; MFF; mitochondrial fission factor; MFN1; mitofusin-1; MFN2; mitofusin-2; mtDNA; mitochondrial DNA; mtNOD; C57BL/6NTac-mtNODLt
The roles of subcellularly located EGFR in autophagy
Keywords: grandpa1; AMPK; AMP-activated protein kinase; ATG; autophagy-related; BCL2; B-cell lymphoma 2; BCL2L1; BCL2 like 1; BNIP3; BCL2/Adenovirus E1B-binding protein Nip3; CME; clathrin-mediated endocytosis; cytoSTAT3; cytoplasmic STAT3; Dsbs; double strand breaks; ECD; e