Keywords: احتمال باز بودن; RyR; ryanodine receptor; [Ca2+]i; intracellular Ca2+ concentration; IP3R; inositol trisphosphate receptor; ER; endoplasmic reticulum; TC; terminal cisternae; LSR; longitudinal sarcoplasmic reticulum; CICR; Ca2+ induced Ca2+ release; SERCA; sarco-endoplasm
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Spontaneous activity, singly bound states and the impact of alpha1Phe64 mutation on GABAAR gating in the novel kinetic model based on the single-channel recordings
Keywords: احتمال باز بودن; GABAA receptor; γ-aminobutyric acid; Single-channel recordings; Kinetic model; Intermediate states; Spontaneous activity; AChR(s); acetylcholine receptor(s); ALA; α1F64Aβ2γ2 mutant(s), α1Phe64Alaβ2γ2 mutant(s); cDNA; complementary deoxyribonucleic
The mammalian skeletal muscle DHPR has larger Ca2+ conductance and is phylogenetically ancient to the early ray-finned fish sterlet (Acipenser ruthenus)
Keywords: احتمال باز بودن; EC; excitation-contraction; DHPR; dihydropyridine receptor; RyR1; ryanodine receptor type-1; SR; sarcoplasmic reticulum; CICR; Ca2+-induced Ca2+ release; GLT; immortalized DHPRα1S-null murine myotubes; Po; open probability; Ts3R; teleost-specific 3rd rou
Calcium/calmodulin-dependent serine protein kinase CASK modulates the L-type calcium current
Keywords: احتمال باز بودن; L-Type calcium channel; CASK; Regulation; Open probability;
Modeling the light-induced electric potential difference (ÎΨ), the pH difference (ÎpH) and the proton motive force across the thylakoid membrane in C3 leaves
Keywords: احتمال باز بودن; ATP; adenosine triphosphate; BC; buffer capacity; bH, bL; the high and low potential hemes b of the cytochrome b6f complex; CBC; Calvin-Benson cycle; CD; charge difference; CET; cyclic electron transport; COsp; coefficient which relates ÎΨs to ÎpH; CS;
Distinct mechanisms underlying cholesterol protection against alcohol-induced BK channel inhibition and resulting vasoconstriction
Keywords: احتمال باز بودن; BK; voltage- and calcium-gated potassium channels of large conductance; CLR; cholesterol; CRAC; cholesterol recognition amino acid consensus; ent-cholesterol; enantiomeric cholesterol; I/O; inside-out (membrane patch); KO; knockout; LDL; low-density lipop
Hydrophobic interactions between the S5 segment and the pore helix stabilizes the closed state of Slo2.1 potassium channels
Keywords: احتمال باز بودن; Ic-rel; constitutive Irel; Irel; current normalized to that induced by 6Â mM NFA; ISlo2.1; Slo2.1 current; KNa; Na+-activated K+; Â NFA; niflumic acid; Po; open probability; TEVC; two-electrode voltage clamp; Vt; test voltage; wt; wild-type; Biophysics; P
Mg2+-dependent facilitation and inactivation of L-type Ca2+ channels in guinea pig ventricular myocytes
Keywords: احتمال باز بودن; Mg2+; Ca2+ channels; Open probability; Open time; Inside-out configuration
Microscopic mechanisms for long QT syndrome type 1 revealed by single-channel analysis of IKs with S3 domain mutations in KCNQ1
Keywords: احتمال باز بودن; Cf, Ci, Cs; fast, intermediate, slow closed state; G-V; voltage dependence of opening; IKs; slowly activating delayed rectifier potassium current; LQTS; long QT syndrome; O1, O2; short and longer open states; Po; open probability; S2, S3, S4; second, thir
Aging decreases the contribution of MaxiK channel in regulating vascular tone in mesenteric artery by unparallel downregulation of α- and β1-subunit expression
Keywords: احتمال باز بودن; BP; blood pressure; BW; body weight; CVDs; cardiovascular diseases; [Ca2+]i; intracellular Ca2+ concentration; DBP; diastolic blood pressure; G; conductance; HR; heart rate; HP; holding potential; HW; heart weight; IbTX; iberiotoxin; MaxiK (or BKCa); larg
RyR3 in situ regulation by Ca2+ and quercetin and the RyR3-mediated Ca2+ release flux in intact Jurkat cells
Keywords: احتمال باز بودن; Ryanodine receptor; Open probability; Binding site; Quercetin; Fluorescence; Jurkat cells;
A calcium-permeable non-selective cation channel in the thick ascending limb apical membrane of the mouse kidney
Keywords: احتمال باز بودن; CTAL; cortical thick ascending limb; Er; reversal potential; FA; flufenamic acid; IMCD; inner medullary collecting duct; NSC channel; non-selective cation channel; NSCCa channel; calcium-activated non-selective cation channel; Po; open probability; TRP; t
Ranolazine stabilizes cardiac ryanodine receptors: A novel mechanism for the suppression of early afterdepolarization and torsades de pointes in long QT type 2
Keywords: احتمال باز بودن; Ranolazine; Action potential durations; Cycle length; Early afterdepolarizations; Torsades de pointes; Long QT type 2; Intracellular free calcium; Sarcoplasmic reticulum; Cardiac ryanodine receptor; Open probability; Shannon-Puglisi model; Mahajan UCLA mo
Bi-stability, hysteresis, and memory of voltage-gated lysenin channels
Keywords: احتمال باز بودن; BLM; Bilayer Lipid Membrane; I-V; current-voltage; Popen; open probability; PFP; pore-forming protein; PFT; pore-forming toxin; V1/2; midway voltage of activation; Lysenin; Voltage-gated channels; Hysteresis; Memory; Pore-forming toxins;
Effects of Resibufogenin and Cinobufagin on voltage-gated potassium channels in primary cultures of rat hippocampal neurons
Keywords: احتمال باز بودن; RBG; Resibufogenin; CBG; Cinobufagin; kV channels; voltage-gated potassium channels; IK; outward delayed-rectifier potassium currents; IA; outward transient potassium currents; CNS; central nervous system; RP; resting potential; AP; action potential; DMEM
Cav1.2 calcium channel is glutathionylated during oxidative stress in guinea pig and ischemic human heart
Keywords: احتمال باز بودن; Cav1.2; α1C subunit (Cav1.2) channel protein; CK; creatine kinase; DTNB; dithiobis-nitrobenzoic acid; DTT; dithiothreitol; GSH; glutathione; GSSG; oxidized glutathione; ICa-L; L-type Ca2+ channel current; I/R; ischemia-reperfusion; KHB; Krebs-Hensele
Elementary properties of Kir2.1, a strong inwardly rectifying K+ channel expressed by pigeon vestibular type II hair cells
Keywords: احتمال باز بودن; vestibular; hair cell; Kir; anomalous rectifier; single channel; gating; CHO; Chinese hamster ovary; EK; equilibrium potential for K+; External_std; oxygen-saturated extracellular solution; ICa; calcium current; Ih; mixed Na+/K+ current; IKir; inwardly re
Cellular neuroscienceSubtype-dependence of N-methyl-d-aspartate receptor modulation by pregnenolone sulfate
Keywords: احتمال باز بودن; glutamate receptor; N-methyl-d-aspartate receptor; neurosteroid; allosteric modulation; open probability; IC50; concentration of pregnenolone sulfate that produces 50% inhibition; EC50; concentration of pregnenolone sulfate that produced 50% potentiation;
Empirical considerations regarding the use of ensemble-variance analysis of macroscopic currents
Keywords: احتمال باز بودن; Unitary current properties; Single channel conductance; Open probability; Noise; Fluctuation analysis; Non-stationary noise analysis
Direct binding of estradiol enhances Slack (sequence like a calcium-activated potassium channel) channels' activity
Keywords: احتمال باز بودن; estrogen; ion channel; neuron; electrophysiology; non-genomic; estrogen receptor; BSA; bovine serum albumin; cDNA; complementary deoxyribonucleic acid; CNS; central nervous system; E2; 17β-estradiol; EGTA; ethylene glycol-bis-(b-aminoethyl ether) N,N,Nâ
The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca2Â +-release channel
Keywords: احتمال باز بودن; AC6; Adenylate cyclase type 6; AKT/PKB; Protein kinase B; ANF; Atrial natriuretic factor; Bcl; B-cell lymphoma; BH; Bcl-2 homology domain; CaMKII; Ca2Â +/calmodulin-dependent protein kinase II; DT40 TKO; DT40 triple knockout; EMT; Epithelial-mesenchymal t