Impact of titanium ions on osteoblast-, osteoclast- and gingival epithelial-like cells
Keywords: Dental implant; Titanium ion; RANKL; OPG
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Titanium ion induces necrosis and sensitivity to lipopolysaccharide in gingival epithelial-like cells
Keywords: Ti; titanium; RANKL; receptor activator of NF-κB ligand; OPG; osteoprotegerin; TLR; toll-like receptor; LPS; lipopolysaccharide; LDH; lactate dehydrogenase; RT-PCR; reverse transcription polymerase chain reaction; Pg; Porphyromonas gingivalis; ICP; induc
Tumor-stroma co-evolution in prostate cancer progression and metastasis
Keywords: AR; androgen receptor; ARCaP; androgen refractory prostate cancer; β2M; β2-microglobulin; BDNF; brain derived neurotropic factor; BMP; bone morphogenetic protein; BSP; bone sialoprotein; CAF; cancer-associated fibroblast; CCL5; chemokine (C-C) ligand
CCR2 Deficiency Results in Increased Osteolysis in Experimental Periapical Lesions in Mice
Keywords: Bone resorption; CCR2; chemokine receptors; OPG; periapical lesions; RANKL
Differences in gene expression between the otic capsule and other bones
Keywords: Otic capsule; opg; Bmpr1b; Otosclerosis;
Zoledronic acid induces apoptosis and changes the TRAIL/OPG ratio in breast cancer cells
Keywords: Breast cancer; OPG; TRAIL; Zoledronic acid
Regulation of osteoprotegerin pro- or anti-tumoral activity by bone tumor microenvironment
Keywords: Bone tumor; Bone resorption; OPG; RANKL; TRAIL; Proteoglycan;
Receptors for leptin in the otic labyrinth and the cochlear-vestibular nerve of guinea pig are modified in hormone-induced anorexia
Keywords: ObR; leptin receptor; GFAP; glial fibrillary acid protein; PLP; proteolipid protein; OPG; osteoprotegerin; RANK; receptor activator of NF-kB; RANKL; receptor activator of NF-kB ligand; NF-kB; nuclear factor kappa-B; BDNF; brain-derived neurotrophic factor
The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the “Fountain of Youth” to mediate healthful aging
Keywords: Vitamin D receptor; 1,25-Dihydroxyvitamin D3; Calcium metabolism; Phosphate metabolism; Fibroblast growth factor 23; Klotho; CYP24A1; Osteocalcin (BGP); Osteopontin (SSP1); LRP5; TRPV6; RANKL; OPG; β-Catenin; Hairless; S100A8; SOSTDC1
The relationship between the levels of gonadotropic hormones and OPG, leptin, TGF-β1 and TGF-β2 in Chinese adult women
Keywords: OPG; Osteoprotegerin; TGF-β1; Transforming growth factor-β1; TGF-β2; Transforming growth factor-β2; GnRH; Gonadotropin-releasing hormone; TNF-α; Tumor necrosis factor-α; BMD; Bone mineral density; IL; Interleukin; RANKL; Receptor activator of the nu
Icariin isolated from Epimedium pubescens regulates osteoblasts anabolism through BMP-2, SMAD4, and Cbfa1 expression
Keywords: Icariin; Osteoblast; Gene expression; BMP-2; SMAD4; Cbfa1; OPG; RANKL
Comparison of Tumor and Microenvironment Secretomes in Plasma and in Platelets during Prostate Cancer Growth in a Xenograft Model
Keywords: G-CSF; granulocyte colony-stimulating factor; GM-CSF; granulocyte-macrophage colony-stimulating factor; HGF; hepatocyte growth factor; IL; interleukin; MCP-1; monocyte chemotactic protein 1; MMP; matrix metalloproteinase; OPG; osteoprotegrin; OPN; osteopo
Bone marrow adipocytes support dexamethasone-induced osteoclast differentiation
Keywords: RANKL; OPG; Bone marrow adipocyte; Osteoclastogenesis; Glucocorticoid
RANK Ligand: A Key Role in Cancer-Induced Bone Destruction?
Keywords: Bone; Bone metastases; Cancer; Cancer treatment-induced bone loss; Denosumab; OPG; Osteoprotegerin; RANK; RANK Ligand
Relationship between age-related serum concentrations of TGF-β1 and TGF-β2 and those of osteoprotegerin and leptin in native Chinese women
Keywords: TGF-β1; Transforming growth factor-β 1; TGF-β2; Transforming growth factor-β 2; OPG; Osteoprotegerin; BMD; Bone mineral density; WHO; World Health Organization; BMI; Body mass index; NW; Normal weight; OW; Overweight; OB; Obesity; PRE; Premenopausal;
Effect of oral erythromycin therapy in patients with aseptic loosening of joint prostheses
Keywords: TNF α; tumor necrosis factor alpha; IL-1β; interleukin 1 beta; TRAP; tartrate-resistant acid phosphatase; AL; aseptic loosening; TJR; total joint replacement; EM; erythromycin; RANKL; nuclear factor kappa B ligand; OPG; osteoprotegerin.; Erythromycin; W
Increased RANK ligand in bone marrow of orchiectomized rats and prevention of their bone loss by the RANK ligand inhibitor osteoprotegerin
Keywords: Androgen ablation; Micro-CT; OPG; Orchiectomy; RANKL
Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts
Keywords: Osteoblasts; IL-6; OPG; Mechanical stimuli
IL-4 alters expression patterns of storage components of vascular endothelial cell-specific granules through STAT6- and SOCS-1-dependent mechanisms
Keywords: Ang-2; angiopoietin-2; EC; endothelial cell; LAMP-3; lysosomal-associated membrane protein 3; OPG; osteoprotegerin; qRT-PCR; quantitative real-time reverse transcription-polymerase chain reaction; SOCS; suppressor of cytokine signaling; STAT6; signal tran
Osteoprotegerin/RANK/RANKL axis in cardiac remodeling due to immuno-inflammatory myocardial disease
Keywords: OPG; RANKL; Cardiac remodeling; IL-17; Extracellular matrix
Impact of the microgravity environment in a 3-dimensional clinostat on osteoblast- and osteoclast-like cells
Keywords: Osteoblast cells; Osteoclast cells; 3D clinostat; Microgravity; RANKL; OPG;
Influence of RANKL inhibition on immune system in the treatment of bone diseases
Keywords: RANK; RANKL; OPG; Osteoclast; B cell; T cell; Dendritic cell
Mechanical regulation of osteoclastic genes in human osteoblasts
Keywords: Osteoblast; Osteoclast; Mechanotransduction; RANKL; OPG; OCIL; M-CSF
Cementoblast response to low- and high-intensity ultrasound
Keywords: Ultrasound; Cementoblast; Root resorption; RANKL; OPG
Improvement in Biomarkers of Bone Formation During Infliximab Therapy in Pediatric Crohn's Disease: Results of the REACH Study
Keywords: BMI; body mass index; BSAP; bone specific alkaline phosphatase; CTX-1; C-telopeptide cross-links of type I collagen; DPD; deoxypyridinoline; ELISA; enzyme-linked immunosorbent assay; IL; interleukin; OPG; osteoprotegerin; PCDAI; Pediatric Crohn's Disease
Relationship between age-related reference values of serum osteoprotegerin and leptin in native Chinese women and compared with those in women of other races
Keywords: OPG; Osteoprotegerin; RANKL; Receptor activator of the NF-κB ligand; BMD; Bone mineral density; MS; Menopausal status; AM; Age at menopause; YSM; Years since menopause; NHW; Non-Hispanic white; NHB; Non-Hispanic black; MA; Mexican American.; Aging; Ethni
Differential Patterns of Receptor Activator of Nuclear Factor Kappa B Ligand/Osteoprotegerin Expression in Human Periapical Granulomas: Possible Association with Progressive or Stable Nature of the Lesions
Keywords: Bone resorption; OPG; periapical granulomas; RANKL; real time-PCR
Functions of RANKL/RANK/OPG in bone modeling and remodeling
Keywords: Bone resorption; Osteoclasts; RANKL; RANK; OPG
Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading
Keywords: Osteocyte; Osteoclast; RANKL; OPG; Mechanotransduction
RNA interference of the BMPR-IB gene blocks BMP-2-induced osteogenic gene expression in human bone cells
Keywords: BMP receptor-IB; BMP-2; RNA interference; Bone cells; BMP; bone morphogenetic proteins; BMPR; bone morphogenetic protein receptor; TGF-β; transforming growth factor β; ALP; alkaline phosphatase; Col I; type-I collagen; OP; osteopontin; BSP; bone sialopr
Interpretation of Biomarkers of Bone Metabolism in Children: Impact of Growth Velocity and Body Size in Healthy Children and Chronic Disease
Keywords: BMI; Body mass index; BSAP; Bone-specific alkaline phosphatase; CV; Coefficient of variation; DPD; Urine deoxypyridinoline to creatinine ratio; DXA; Dual energy x-ray absorptiometry; IL-1β; Interleukin-1β; NFκB; Nuclear factor κB; OPG; Osteoprotegerin
Prolactin decreases the expression ratio of receptor activator of nuclear factor κB ligand/osteoprotegerin in human fetal osteoblast cells
Keywords: Alkaline phosphatase; hFOB; OPG; Osteocalcin; PI3K; Prolactin receptor; RANKL;
RANK ligand as a therapeutic target for bone metastases and multiple myeloma
Keywords: RANK; RANKL; OPG; Bone metastasis; Osteoclast; Skeletal complications; Breast cancer; Prostate cancer; Multiple myeloma
Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells
Keywords: Osteoblast; U2OS; Estradiol; Estrogen receptor; OPG; IL-6
The Effect of Estrogen Deficiency on Receptor Activator of Nuclear Factor Kappa B Ligand and Osteoprotegerin Synthesis in Periapical Lesions Induced in Rats
Keywords: Estrogen; OPG; periapical lesion; RANKL
Serum osteoprotegerin levels in patients with acute atherothrombotic stroke and lacunar infarct
Keywords: BMI; body mass index; DBP; diastolic blood pressure; ELISA; enzyme-linked immunosorbent assay; HDL-C; high density lipoprotein-cholesterol; LDL-C; low density lipoprotein-cholesterol; LVD; large-vessel disease; OPG; osteoprotegerin; RANKL; receptor activa
Phosphodiesterase 4 inhibitor regulates the TRANCE/OPG ratio via COX-2 expression in a manner similar to PTH in osteoblasts
Keywords: Phosphodiesterase 4; Parathyroid hormone; COX-2; TRANCE; OPG; Osteoblast; Osteoclast;
Serum OPG and RANKL levels before and after intravenous bisphosphonate treatment in Paget's disease of bone
Keywords: Paget's disease of bone; OPG; RANKL; NF-kB signaling; Pamidronate
Vertebral Fractures and Role of Low Bone Mineral Density in Crohn's Disease
Keywords: BMD; bone mineral density; BMI; body mass index; CD; Crohn's disease; CRP; C-reactive protein; DXA; dual energy x-ray absorptiometry; HR; height reduction; IL; interleukin; OPG; osteoprotegerin; PTH; parathyroid hormone; RANK; receptor activator of nucl
Regulation of RANKL and OPG gene expression in human gingival fibroblasts and periodontal ligament cells by Porphyromonas gingivalis: A putative role of the Arg-gingipains
Keywords: Porphyromonas gingivalis; RANKL; OPG; Periodontal fibroblasts; Bone resorption; Gingipains
Neuropeptides modulate RANKL and OPG expression in human periodontal ligament cells
Keywords: Substance P; CGRP; RANKL; OPG; Periodontal ligament cell
Local delivery of osteoprotegerin inhibits mechanically mediated bone modeling in orthodontic tooth movement
Keywords: RANKL inhibitor; OPG; Osteoclast; Micro-computed tomography; Tooth movement;
Bone loss in children with Crohn disease: Evidence of “osteoimmune” alterations
Keywords: BMD; Bone mineral density; CD; Crohn disease; DXA; Dual-energy x-ray absorptiometry; IFN; Interferon; OPG; Osteoprotegerin; RANKL; Receptor activator of nuclear factor-κB ligand;
Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling
Keywords: Oscillatory fluid flow; Mechanotransduction; RANKL; OPG; Osteoclastogenesis
OPG, RANK-L, bone metabolism, and BMD in patients on peritoneal dialysis and hemodialysis
Keywords: OPG; RANK-L; Bone mineral density; Renal osteodystrophy; End-stage renal failure; Markers of bone turnover
Long wave ultrasound may enhance bone regeneration by altering OPG/RANKL ratio in human osteoblast-like cells
Keywords: Osteoblasts; OPG; RANKL; Long wave ultrasound
Osteoprotegerin (OPG) binds with Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL): Suppression of TRAIL-induced apoptosis in ameloblastomas
Keywords: Ameloblastomas; AM-1; OPG; RANKL; TRAIL; Apoptosis
Transcriptomics and proteomics: Advancing the understanding of genetic basis of fracture healing
Keywords: ALP; alkaline phosphatase; Ang; angiogenin; BMP; bone morphogenetic protein; BMPR; bone morphogenetic protein receptor; BSP; bone sialoproteins; Cbfα1; core binding factor α1; c-fos; cellular osteosarcoma oncogene; c-myc; cellular myelocytomatosis oncog
Soluble glucocorticoid-induced tumor necrosis factor receptor stimulates osteoclastogenesis by down-regulation of osteoprotegerin in bone marrow stromal cells
Keywords: sGITR; GITRL; Osteoclastogenesis; Bone marrow stromal cells; OPG
Regulation of RANKL by biomechanical loading in fibrochondrocytes of meniscus
Keywords: Mechanical strain; Fibrocartilage; RANKL; RANK; OPG