Keywords: حمل کننده آنیون آلی; Organic anion transporter; Drug transport; Regulation; Dexamethasone; Serum and glucocorticoid-inducible kinase;
مقالات ISI حمل کننده آنیون آلی (ترجمه نشده)
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Keywords: حمل کننده آنیون آلی; ABC; ATP-Binding cassette; ARPE-19; human retinal pigment epithelial cells; BBB; blood-brain barrier; BCRP; breast cancer resistant protein; CNS; central nervous system; 3D-QSAR; 3-Dimensional Quantitative Structure Activity; ELC; elacridar; LAT1; l-Type
Keywords: حمل کننده آنیون آلی; ARV; antiretroviral; CHO; Chinese Hamster Ovary; CID; collision-induced dissociation; DMEM/F12; Dulbecco's Modified Eagle's Medium: Ham's F12 Medium; DMF; dimethylformamide; DMSO; dimethylsulfoxide; GGT; γ-glutamyltransferase; HIV; human immunodefi
Keywords: حمل کننده آنیون آلی; Rhein; Rhein acyl glucuronide; Methotrexate; Organic anion transporter; Drug-drug interaction; AUC; area under the plasma time-concentration curve; ES; estrone sulfate; HBSS; Hank's balanced salt solution; HEK293; human embryonic kidney 293; IS; internal
Keywords: حمل کننده آنیون آلی; AA; aristolochic acid; AAI; aristolochic acid I; AAII; aristolochic acid II; AAI+AAII; mixture of aristolochic acid I and II; AAN; aristolochic acid nephropathy; BUN; blood urea nitrogen; GLUT; glucose transporter; OAT; organic anion transporter; OSOM; ou
Keywords: حمل کننده آنیون آلی; cilostazol; hepatic transport; OATP 1B1/1B3; biliary excretion; efflux transporter; AP; apical; BL; basolateral; DMEM; Dulbecco's modified Eagle's medium; EGCG; (-)-epigallocatechin gallate; HEK293 cells; human embryonic kidney cells; MDCKII cells; Madi
Keywords: حمل کننده آنیون آلی; absorption; computational ADME; efflux pumps; in vitro models; organic cation transporters; P-glycoprotein; peptide transporters; pulmonary delivery/absorption; ABC transporters; organic anion-transporting polypeptide transporters; BAL; bronchoalveolar l
Keywords: حمل کننده آنیون آلی; ATP; adenosine triphosphate; BCRP; breast cancer resistance protein; CKD; chronic kidney disease; COL1A1; collagen type 1A1; ECM; extracellular matrix; ESRD; end-stage renal disease; FN1; fibronectin 1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; 7-
Keywords: حمل کننده آنیون آلی; Intracellular drug concentration; Pharmacodynamics; OCT; MATE; PMAT; Drug transporter; ABC; ATP-binding cassette; ACC; acetyl-CoA carboxylase; AMP; adenosine monophosphate; AMPK; AMP-activated protein kinase; AUC; area under the concentration time curve;
Keywords: حمل کننده آنیون آلی; AAV; Adeno-associated virus; ABC; ATP-binding cassette; AD; Alzheimer's disease; BAC; Bacterial artificial chromosome; BBB; Blood-brain barrier; CNS; Central nervous system; EAE; Experimental autoimmune encephalomyelitis; IHC; Immunohistochemistry; MS;
Keywords: حمل کننده آنیون آلی; Statin; Adverse effects; Drug-drug interactions; Pharmacogenetics; ABC; ATP-binding cassette; ASCVD; atherosclerotic cardiovascular disease; CPIC; Clinical Pharmacogenetic Implementation Consortium; CK; creatinine kinase; CV; cardiovascular; CVD; cardio
Keywords: حمل کننده آنیون آلی; 3D; three-dimensional; c log P; the calculated log octanol/water partition coefficient; DNA; deoxyribonucleic acid; ATP; adenosine triphosphate; HPT1; intestinal peptide-associated transporter 1; PEPT1; peptide transporter 1; OCT; organic cation transpo
Keywords: حمل کننده آنیون آلی; Steviol glucuronide; OAT3; Uptake transport; Food-drug interaction; BCRP; breast cancer resistant protein; MATE; multidrug and toxin extrusion protein; MRP; multidrug resistant protein; OAT; organic anion transporter; OATP; organic anion transport protein
Keywords: حمل کننده آنیون آلی; cNMPs; Nucleotidyl cyclases; Phosphodiesterases; Protein kinases; Bacterial toxins; Second messengers; AC; adenylyl cyclase; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CC; cytidylyl cyclase; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cGMP; guanos
Keywords: حمل کننده آنیون آلی; Avedev; average of the absolute deviations of data points from their mean; BBB; blood-brain barrier; LY; Lucifer Yellow; MCT; monocarboxylic acid transport; OAT; organic anion transporter; Blood-brain barrier; Chlorogenic acids; Coffee; Metabolites; P
Keywords: حمل کننده آنیون آلی; Organic anion transporter; Ameloblast; Enamel; Absorption; Lucifer Yellow;
Keywords: حمل کننده آنیون آلی; 7-OHC; 7-hydroxycoumarin; 7-OHCG; 7-hydroxycoumarin glucuronide; AA; antimycin A; ciPTEC; conditionally immortalized human renal proximal tubule epithelial cells; CKD; chronic kidney disease; CMPF; 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid; CRF; c
Organic anion transporter 1 (OAT1/SLC22A6) enhances bioluminescence based on d-luciferin-luciferase reaction in living cells by facilitating the intracellular accumulation of d-luciferin
Keywords: حمل کننده آنیون آلی; Bioluminescence imaging; Luciferase; d-luciferin; Organic anion transporter; OAT1; BL; bioluminescence; 6-CF; 6-carboxyfluorescein; d-luc; d-luciferin; Km; Michaelis constant; OAT; organic anion transporter; eLuc; Pyrearinus termitilluminans luciferase;
AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3
Keywords: حمل کننده آنیون آلی; Organic anion transporter; Drug transport; Regulation; Janus kinase 2 inhibitor; Ubiquitin ligase Nedd4-2;
Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics
Keywords: حمل کننده آنیون آلی; ABC; ATP-binding cassette transporter; ADAR; adenosine deaminase acting on RNA; ADH; alcohol dehydrogenase; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; ALS; amyotrophic lateral sclerosis; AZIN1; antizyme inhibitor 1; AMPA; α-amino-3-hydroxy
PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ
Keywords: حمل کننده آنیون آلی; Thyroid hormones; Scaffold protein; PDZ-domain; Gene regulation; Thyroid hormone receptors; 5-HT2A; Serotonin 2A receptor; ABC; ATP-binding cassette transporter; AhR; Transcription factor aryl hydrocarbon receptor; BCRP; Breast cancer resistance protein;
Organic solute carrier 22 (SLC22) family: Potential for interactions with food, herbal/dietary supplements, endogenous compounds, and drugs
Keywords: حمل کننده آنیون آلی; Hepatic transport; Nephrotoxicity; Organic anion transporter; Organic cation transporter; Renal transport;
Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion
Keywords: حمل کننده آنیون آلی; Biliary excretion; PPARα; Bile acids; Gender difference; 1oBAs; Primary bile acids; 2oBAs; secondary bile acids; 12-OH; 12-hydroxylated bile acid; Asbt; apical sodium-dependent bile acid transporter; BA; bile acid; Baat; bile acid CoA:amino acid N-acyltr
Imaging techniques to study drug transporter function in vivo
Keywords: حمل کننده آنیون آلی; ABC; ATP-binding cassette; AD; Alzheimer's disease; ADME; absorption, distribution, metabolism and elimination; ATP; adenosine triphosphate; AUC; area under the curve; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; BPND; non-displaceabl
Human organic anion transporter 2 is an entecavir, but not tenofovir, transporter
Keywords: حمل کننده آنیون آلی; Entecavir; Tenofovir; Organic anion transporter; Human hepatocytes; Hepatitis B;
Saponins extracted from Dioscorea collettii rhizomes regulate the expression of urate transporters in chronic hyperuricemia rats
Keywords: حمل کننده آنیون آلی; Total saponins of Dioscorea collettii; Dioscoreaceae; Hyperuricemia; Urate transporters; Urate anion transporter 1; Organic anion transporter; Glucose transporter 9;
Zuotai and HgS differ from HgCl2 and methyl mercury in Hg accumulation and toxicity in weanling and aged rats
Keywords: حمل کننده آنیون آلی; Mrp; Multidrug resistance-associated protein; Mdr1b; multidrug resistance gene 1b; OAT; organic anion transporter; OATP; organic anion-transporting polypeptides; OCT; organic cation transporters; Zuotai and HgS; HgCl2 and MeHg; Weanling and aged rats; Hg
Inhibition of organic anion transporter (OAT) activity by cigarette smoke condensate
Keywords: حمل کننده آنیون آلی; Drug transporter; Cigarette smoke; Pharmacokinetics; Organic anion transporter; Heterocyclic amines;
Prediction of renal transporter-mediated drug-drug interactions for a drug which is an OAT substrate and inhibitor using PBPK modelling
Keywords: حمل کننده آنیون آلی; AUC; area under the curve; DDI; drug-drug interaction; fu; fraction unbound; IC50; inhibition constant; IV; intravenous; IVIVE; in vitro/in vivo extrapolation; Ki; inhibition constant; OAT; organic anion transporter; PBPK; physiologically based pharmacoki
Evaluation of Renal Transporter Inhibition Using Creatinine as a Substrate In Vitro to Assess the Clinical Risk of Elevated Serum Creatinine
Keywords: حمل کننده آنیون آلی; renal transporter; drug interactions; in vitro-in vivo correlation; renal clearance; inhibition; AUC; area under the concentration curve; CLcr; creatinine renal clearance; Cmax; maximal total plasma concentration; Cmax,u; maximal unbound plasma concen
Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban
Keywords: حمل کننده آنیون آلی; drug interactions; solute transporters; organic anion transporters (OAT); pharmacokinetics/pharmacodynamics; renal transport; BCRP; breast cancer resistance protein; CCK8; cholecystokinin-8; E217βG; estradiol 17β-D-glucuronide; E-sul; estrone 3-sulfate;
Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE3
Keywords: حمل کننده آنیون آلی; NSAIDs; non-steroidal anti-inflammatory drugs; EPA-E; eicosapentaenoic acid ethyl ester; AA; arachidonic acid; PGE2; prostaglandin E2; PGE3; prostaglandin E3; EP; PGE receptor; OATP; organic anion transporting polypeptide; OAT; organic anion transporter;
Serum- and glucocorticoid-inducible kinase SGK2 regulates human organic anion transporters 4 via ubiquitin ligase Nedd4-2
Keywords: حمل کننده آنیون آلی; Organic anion transporter; Drug transport; Regulation; Serum and glucocorticoid-inducible kinase; Ubiquitin ligase; Ubiquitination
Aristolochic acid I is a substrate of BCRP but not P-glycoprotein or MRP2
Keywords: حمل کننده آنیون آلی; AA; Aristolochic acid; AAI; Aristolochic acid I; AAN; Aristolochic acid nephropathy; BCRP; Breast cancer resistance protein; DMEM; Dulbecco's Modification of Eagle's Medium; FBS; Fetal bovine serum; HBSS; Hank's balanced salt solution; MRP2; Multidr
The involvement of selected membrane transport mechanisms in the cellular uptake of 177Lu-labeled bombesin, somatostatin and gastrin analogues
Keywords: حمل کننده آنیون آلی; Megalin; Nephrotoxicity; Organic anion transporter; Organic cation transporter; Fluid phase endocytosis; Peptides
Na+-dependent and Na+-independent betaine transport across the apical membrane of rat renal epithelium
Keywords: حمل کننده آنیون آلی; BBMV; brush-border membrane vesicles; Kt; apparent affinity constant; Vmax; maximal transport velocity; SIT1; Sodium/Imino-acid Transporter 1; TEA; tetraethylammonium; GABA; gamma-aminobutyric acid; BGT1; betaine/GABA transporter 1; PAT; proton-coupled am
Expression of xenobiotic transporters in the human renal proximal tubule cell line RPTEC/TERT1
Keywords: حمل کننده آنیون آلی; 4-Di-1-ASP; 4-(4-(Dimethylamino)styryl)-N-Methylpyridinium Iodide; CsA; Cyclosporine A; primary hPT; human primary proximal tubule cells; MATE; multidrug and toxin extrusion proteins; OAT; organic anion transporter; OATP; organic anion polypeptide transpo
In vitro interaction of clopidogrel and its hydrolysate with OCT1, OCT2 and OAT1
Keywords: حمل کننده آنیون آلی; Organic cation transporter; Organic anion transporter; Clopidogrel; Clopidogrel carboxylate; Drug-drug interactions; Inhibition;
Transporter-mediated Prostaglandin E2 Elimination across the Rat Blood-brain Barrier and Its Attenuation by the Activation of N-methyl-D-aspartate Receptors
Keywords: حمل کننده آنیون آلی; blood-brain barrier; calcium; L-glutamate; intracellular calcium ion; N-methyl-D-aspartate receptor; organic anion transporter; prostaglandin E2;
Methotrexate-bestatin interaction: Involvement of P-glycoprotein and organic anion transporters in rats
Keywords: حمل کننده آنیون آلی; MTX; methotrexate; DDI; drug-drug interaction; P-gp; P-glycoprotein; OAT; organic anion transporter; MRP; multidrug resistance-associated protein; BCRP; breast cancer resistance protein; OATP; organic anion transporting polypeptide; KRB; Krebs-Ringer
Chlorothiazide is a Substrate for the Human Uptake Transporters OAT1 and OAT3
Keywords: حمل کننده آنیون آلی; drug transport; renal metabolism; organic anion transporter; drug interactions; renal transport; chlorothiazide; probenecid; diclofenac; furosemide;
Reduced Renal Clearance of Cefotaxime in Asians with a Low-Frequency Polymorphism of OAT3 (SLC22A8)
Keywords: حمل کننده آنیون آلی; organic anion transporter; cefotaxime; tubular secretion; OAT3; polymorphisms; pharmacogenomic; pharmacokinetics; renal clearance
Precise comparison of protein localization among OCT, OAT, and MATE in human kidney
Keywords: حمل کننده آنیون آلی; active transport; renal excretion; membrane transporter; drug transport; organic anion transporter; organic cation transporter; elimination; renal clearance; multidrug and toxin extrusion
Drugs interacting with organic anion transporter-1 affect uptake of Tc-99m-mercaptoacetyl-triglycine (MAG3) in the human kidney: Therapeutic drug interaction in Tc-99m-MAG3 diagnosis of renal function and possible application of Tc-99m-MAG3 for drug devel
Keywords: حمل کننده آنیون آلی; MAG3; Organic anion transporter; OAT1; Drug interaction; Kidney
Inhibitory effect of 1α,25-dihydroxyvitamin D3 on excretion of JBP485 via organic anion transporters in rats
Keywords: حمل کننده آنیون آلی; JBP485; 1α,25-Dihydroxyvitamin D3; Organic anion transporter; Pharmacokinetic interaction;
Placental and fetal disposition of mercuric ions in rats exposed to methylmercury: Role of Mrp2
Keywords: حمل کننده آنیون آلی; CH3Hg+; methylmercury; CH3HgCl; methylmercury chloride; CH3[203Hg+]; radioactive methylmercury; Cys; cysteine; Cys-S-CH3Hg; cysteine-thiol-conjugates of methylmercury; Mrp; multidrug resistance-associated transporter; OAT; organic anion transporter; DCM;
Carrier-mediated transport of quercetin conjugates: Involvement of organic anion transporters and organic anion transporting polypeptides
Keywords: حمل کننده آنیون آلی; COX2, cyclooxygenase-2; HBSS, hank's balanced salt solution; OATs, organic anion transporters; OATPs, organic anion transporting polypeptidesQuercetin; HepG2; Carrier-mediated transport; Organic anion transporter; Organic anion transporting polypeptide
Uricosuric and nephroprotective properties of Ramulus Mori ethanol extract in hyperuricemic mice
Keywords: حمل کننده آنیون آلی; BUN; blood urea nitrogen; ERM; ethanol extract of Ramulus Mori; FEUA; fractional excretion of uric acid; GLUT9; glucose transporter 9; HPLC; high-performance liquid chromatography; OAT; organic anion transporter; OCTs; organic cation transporters; OCTNs;
Original Full Length ArticleGender- and dose-related effects of cyclosporin A on hepatic and bone metabolism
Keywords: حمل کننده آنیون آلی; ANOVA; analysis of variance; BMD; bone mineral density; BW; body weight; CsA; cyclosporin A; E2; 17β-estradiol; GX; gonadectomized; HRT; hormone replacement therapy; MCT; medium chain triglycerides; OATP; organic anion transporter; OVX; ovariectomized; O
Transcriptional Regulation of Organic Anion Transporting Polypeptide SLCO4C1 as a New Therapeutic Modality to Prevent Chronic Kidney Disease
Keywords: حمل کننده آنیون آلی; Organic anion-transporting polypeptide transporters; Organic anion transporter; ABC transporters; Membrane transport; Uremic toxin; Statin; Chronic kidney disease; Metabolome analysis; Capillary electrophoresis; Mass spectrometry