The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer
Keywords: CHD4; p21; HDAC1; BRCAness; DNA damage;
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
LncRNA MEG3 has anti-activity effects of cervical cancer
Keywords: lncRNA MEG3; Hela; PI3K; AKT; Bcl-2; Bax; P21; MMP-2; MMP-9;
Pancreatic stellate cells increase pancreatic cancer cells invasion through the hepatocyte growth factor /c-Met/survivin regulated by P53/P21
Keywords: Pancreatic stellate cells; HGF/c-Met; Survivin; P53; P21;
Research articleA naturally occurring mixture of tocotrienols inhibits the growth of human prostate tumor, associated with epigenetic modifications of cyclin-dependent kinase inhibitors p21 and p27
Keywords: T3; tocotrienol; T; tocopherol; HDAC; histone deacetylase; HAT; histone acetyltransferase; CDK; cyclin-dependent kinase; HDAC; Prostate cancer; p21; p27; Tocotrienol; VCaP;
Cell cycle activation in p21 dependent pathway: An alternative mechanism of organophosphate induced dopaminergic neurodegeneration
Keywords: Dichlorvos; Oxidative stress; p21; Cyclin-D1; Neurodegeneration;
1,25-Dihydroxyvitamin D3 suppresses gastric cancer cell growth through VDR- and mutant p53-mediated induction of p21
Keywords: 1,25-Dihydroxyvitamin D3; VDR; Gastric cancer; p21; Mutant p53;
Critical role of p21 on olaquindox-induced mitochondrial apoptosis and S-phase arrest involves activation of PI3K/AKT and inhibition of Nrf2/HO-1pathway
Keywords: Olaquindox; p21; ROS; Mitochondrial apoptosis; S-phase arrest; PI3K/AKT and Nrf2/HO-1 pathway;
Tumoral FOXP3 expression is associated with favorable clinicopathological variables and good prognosis in gastric adenocarcinoma: the tumor suppressor function of tumoral FOXP3 is related with the P21 expression in gastric adenocarcinoma
Keywords: Tumoral FOXP3; P21; Gastric adenocarcinoma; Tumor suppression protein; Treg;
Dicarbonyls induce senescence of human vascular endothelial cells
Keywords: Glyoxal; Methylglyoxal; Dicarbonyl stress; Senescence; Carboxymethyllysine; MG-H1; p21; Glo-I;
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells
Keywords: KSHV; Kaposi's sarcoma-associated herpesvirus; B; butyrate; ERK; Extracellular Signal-regulated Kinase; MAPKs; Mitogen-Activated Protein Kinases; PD98059; ERK inhibitor; PEL; Primary Effusion Lymphoma; PKCs; protein kinases C; Q; quercetin; ROS; reactive
Aqueous areca nut extract induces oxidative stress in human lung epithelial A549 cells: Probable role of p21 in inducing cell death
Keywords: RPMI; Rosewell Park Memorial Institute media; FBS; fetal bovine serum; PBS; phosphate buffered saline; ROS; reactive oxygen species; LPO; lipid peroxidation; LDH; lactate dehydrogenase; GSH-Px; glutathione peroxidase; GST; glutathione S transferase; SOD;
UBE2S associated with OSCC proliferation by promotion of P21 degradation via the ubiquitin-proteasome system
Keywords: APC/C; Cell cycle; G2/M arrest; Oral squamous cell carcinoma; P21; Ubiquitin-proteasome system;
G2/M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph3PAu[SC(OR)Â =Â NPh], RÂ =Â Me, Et, and iPr, during zebrafish development
Keywords: Annexin V-FITC; Recombinant annexin V conjugated to fluorescein isothiocyanate; APAF-1; Apoptotic protease activating factor 1; ATR; Ataxia telangiectasia and Rad3-related; Bax; Apoptosis regulator; Bcl-2; B-cell lymphoma 2; BIRC-5; Baculoviral inhibitor
MDM2 Antagonists Counteract Drug-Induced DNA Damage
Keywords: DNA damage; Replication stress; Mitotic inhibitor; MDM2 antagonist; Melanoma; Polyploidy; p21; p53;
LncRNA LINC00341 mediates PM2.5-induced cell cycle arrest in human bronchial epithelial cells
Keywords: PM2.5; LINC00341; Cell cycle arrest; G2/M phase; p21;
Anti-inflammatory activity of chloroquine and amodiaquine through p21-mediated suppression of T cell proliferation and Th1 cell differentiation
Keywords: Amodiaquine; Chloroquine; p21; Proliferation; IFN-γ;
ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells
Keywords: ID4; AR; ADT; p21; FKBP51; bHLH; Cancer; Apoptosis; Migration;
Activation of Notch1 inhibits medial edge epithelium apoptosis in all-trans retinoic acid-induced cleft palate in mice
Keywords: All-trans retinoic acid; Notch1; P21; Medial edge epithelium; Apoptosis;
The CCR4-NOT deadenylase activity contributes to generation of induced pluripotent stem cells
Keywords: The CCR4-NOT complex; iPSC; p21; Eomes;
Radiosensitizing effect of PSMC5, a 19S proteasome ATPase, in H460 lung cancer cells
Keywords: Akt-Mdm2 pathway; H460 cancer cells; PSMC5; p21; Radiosensitivity biomarker;
Multiple functions of p21 in cell cycle, apoptosis and transcriptional regulation after DNA damage
Keywords: Apoptosis; Cell cycle; DNA damage; p21
Inhibitory effect of Erinacines A on the growth of DLD-1 colorectal cancer cells is induced by generation of reactive oxygen species and activation of p70S6K and p21
Keywords: H. erinaceus; Erinacines A; Colorectal cancer cells; ROS; p70S6K; p21
Long-term HIV-1 infection induces an antiviral state in primary macrophages
Keywords: Cell cycle; Macrophage; Cell death; Interferon; p21; ISG;
p21CIP1/WAF1-dependent inhibition of cardiac hypertrophy in response to Angiotensin II involves Akt/Myc and pRb signaling
Keywords: p21; Cdkn1a; p27; Cdkn1b; Myc; Retinoblastoma; Cyclin D2; Cdk; Cell cycle; Cardiac hypertrophy; Heart failure; Cardiac fibrosis; Angiotensin
P21Waf1/Cip1 plays a critical role in furazolidone-induced apoptosis in HepG2 cells through influencing the caspase-3 activation and ROS generation
Keywords: p21; Furazolidone; Apoptosis; ROS; Caspase activation;
China's interregional capital mobility: A spatial econometric estimation
Keywords: C21; P21; Capital mobility; Spatial autocorrelation model; Spatial weight matrix;
Downregulated long non-coding RNA MEG3 in breast cancer regulates proliferation, migration and invasion by depending on p53's transcriptional activity
Keywords: Long non-coding RNA; MEG3; Breast cancer; p53; p21; Transcriptional activity;
Modulation of DNA damage response and induction of apoptosis mediates synergism between doxorubicin and a new imidazopyridine derivative in breast and lung cancer cells
Keywords: DNA damage response; Drug discovery; Doxorubicin; p21; Cyclin-dependent kinase (CDK); Apoptosis;
Lack of mitochondrial DNA impairs chemical hypoxia-induced autophagy in liver tumor cells through ROS-AMPK-ULK1 signaling dysregulation independently of HIF-1α
Keywords: Akt; protein kinase B; AMPK; AMP-activated protein kinase; AVOs; acidic vesicular organelles; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BNIP3L; BCL2/adenovirus E1B 19Â kDa interacting protein 3-like; CCND1; cyclin D1; CFSE; 5-(6)-carboxyfl
SRJ09, a promising anticancer drug lead: Elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy
Keywords: ACUC; Animal Care and Use Committee; AGP; andrographolide; CDK; cyclin dependent kinase; DMSO; dimethyl sulfoxide; DOX; doxorubicin; ERK1/2; extracellular signal-regulated kinases 1/2; FBS; fetal bovine serum; HPLC; high performance liquid chromatography;
SEMA4B inhibits growth of non-small cell lung cancer in vitro and in vivo
Keywords: SEMA4B; Non-small cell lung cancer (NSCLC); PI3K; FoxO1; P21;
Induction of apoptosis by genipin inhibits cell proliferation in AGS human gastric cancer cells via Egr1/p21 signaling pathway
Keywords: Genipin; Programmed cell death; p21; Egr1; Apoptosis;
Chelation of dietary iron prevents iron accumulation and macrophage infiltration in the type I diabetic kidney
Keywords: Diabetic nephropathy; Iron; P21; Proximal tubular cells; Cellular senescence
AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts
Keywords: 53BP1, p53-binding protein 1; AMPK, adenosine monophosphate-activated protein kinase; DSB, double-strand breaks; MEFs, mouse embryonic fibroblasts; NHEJ, nonhomologous end-joiningAMPKα; p21; 53BP1; DNA damage; Cell proliferation; Apoptosis
Ankaferd Blood Stopper induces apoptosis and regulates PAR1 and EPCR expression in human leukemia cells
Keywords: Ankaferd Blood Stopper (ABS); PAR1; EPCR; p21; Apoptosis; Leukemia
Aging-associated subpopulations of human CD8+ T-lymphocytes identified by their CD28 and CD57 phenotypes
Keywords: Cellular aging; CD28; CD57; CXCR2; p16; p21;
Growth and migration of LNCaP prostate cancer cells are promoted by triclosan and benzophenone-1 via an androgen receptor signaling pathway
Keywords: Triclosan; Benzophenone-1; Prostate cancer; Androgen receptor; Cathepsin D; Cyclin E; p21;
Comparative analysis of p53 and p21 proteins in normal cervix and HPV associated precancerous and cancerous lesions of cervix
Keywords: Cervical cancer; HPV-E6; p53; p21; p-p53-ser46;
Myc and cell cycle control
Keywords: Myc; Cell cycle; Proliferation; Cyclin; Cdk; p21; p27;
Novel aberrant genetic and epigenetic events in Friedreich׳s ataxia
Keywords: FRDA; Friedreich׳s ataxia; FXN; frataxin; ISC; iron-sulphur cluster; hPDL; human periodontal ligament; CASP3; active caspase-3; DNMT; DNA methyltransferase; CpG; cytosine phosphate group guanine; TSS; transcription start site; UP; upstream GAA repetiti
Suppression of centrosome protein TACC3 induces G1 arrest and cell death through activation of p38–p53–p21 stress signaling pathway
Keywords: Centrosome; Cell cycle; TACC3; p53; p38; p21
Distinct roles of transforming growth factor-β signaling and transforming growth factor-β receptor inhibitor SB431542 in the regulation of p21 expression
Keywords: SB431542 (PubChem CID: 4521392); Cycloheximide (PubChem CID: 6197); SP600125 (PubChem CID: 8515); MG132 (PubChem CID: 462382)TGF-β; SB431542; p21; Specificity protein 1 (Sp1)
Dietary compounds galangin and myricetin suppress ovarian cancer cell angiogenesis
Keywords: Galangin; Myricetin; p21; Angiogenesis; Ovarian cancer
The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators
Keywords: Fbxl11; Kdm2a; Histone demethylase; p21; Embryogenesis;
miR-200c-SUMOylated KLF4 feedback loop acts as a switch in transcriptional programs that control VSMC proliferation
Keywords: ATRA; all-trans retinoic acid; cdk2; cyclin-dependent kinase 2; HASMC; human aortic smooth muscle cell; HDAC2; histone deacetylase 2; KLF; Krüppel-like factor; LSD1; lysine-specific demethylase 1; miR; microRNA; NCoR; nuclear receptor corepressor; p21; p
Depletion of poly(A)-specific ribonuclease (PARN) inhibits proliferation of human gastric cancer cells by blocking cell cycle progression
Keywords: BSA; bovine serum albumin; CDK; cyclin-dependent kinase; DDR; DNA damage response; DMEM; Dulbecco's modified Eagle's medium; EEP; endonuclease-exonuclease-phosphatase; HRP; Horseradish peroxidase; HU; hydroxyl urea; M-MLV; Moloney murine leukemia viru
Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation
Keywords: ALCL; anaplastic large cell lymphoma; ALOX; lipoxygenase A; CCID; circular chemorepellent induced defect; CYP; cytochrome P450; DCM; dichloromethane extract; EROD; ethoxyresorufin-O-deethylase; HO/PI; Hoechst 33258/propidium iodide; LEC; lymph endothelial
NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity
Keywords: NDRG2; N-myc downstream-regulated gene 2; MRFs; myogenic regulatory factors; Cdk; cyclin-dependent kinase; Rb; retinoblastoma; Myf5; myogenic factor 5; MyoD; myogenic differentiation; p27; p27 kip1; p21; p21 waf1/cip1; Akt; thymoma viral proto-oncogene; P
5-Lipoxygenase is a direct p53 target gene in humans
Keywords: ALOX5; arachidonate 5-lipoxygenase gene; 5-LO; 5-lipoxygenase; PTMs; posttranslational modifications; AA; arachidonic acid; 5-HETE; 5-hydroxyeicosatetraenoic acid; LT; leukotriene; FLAP; 5-lipoxygenase activating protein; HEPES; 4-(2-hydroxyethyl)-1-piper
Sp1 transcription factor: A long-standing target in cancer chemotherapy
Keywords: Anticancer drugs; Prognosis; Sp1; Sp3; Transcription factors; Targeted therapy; AMPKα; AMP-activated protein kinase alpha catalytic subunit; Bcl-2; B cell/lymphoma 2; Bcl-w; member of the Bcl-2 family; Bid; BH3 interacting domain death agonist; CDK; cycl