Monocytes P2X7 purinergic receptor is modulated by glatiramer acetate in multiple sclerosis
Keywords: گیرنده P2X7; Multiple sclerosis; P2X7 receptor; Monocytes; Glatiramer acetate;
مقالات ISI گیرنده P2X7 (ترجمه نشده)
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Calmidazolium selectively inhibits exocytotic glutamate release evoked by P2X7 receptor activation
Keywords: گیرنده P2X7; A-438079; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)-methyl pyridine; BzATP; 2â²-3â²-O-(benzoylbenzoyl)ATP; [Ca2+]i; intracellular Ca2+ concentration; P2X7R; P2X7 receptor; ROI; region of interest; VOCCs; voltage operated calcium channels; Glutamate re
Involvement of P2X4 receptor in P2X7 receptor-dependent cell death of mouse macrophages
Keywords: گیرنده P2X7; BAPTA-AM; 1,2-bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid acetoxymethyl ester; BzATP; 2â²- & 3â²-O-(4-benzoyl) benzoyl-ATP; [Ca2+]i; cytosolic Ca2+ concentration; EtBr; ethidium bromide; ERK; extracellular signal-regulated kinase; LDH; lactate de
Spinal P2X7 receptor mediates microglia activation-induced neuropathic pain in the sciatic nerve injury rat model
Keywords: گیرنده P2X7; P2X7 receptor; Microglia; Chronic constriction of the sciatic nerve(CCI); Brilliant Blue G(BBG); Neuropathic pain;
A consensus segment in the M2 domain of the hP2X7 receptor shows ion channel activity in planar lipid bilayers and in biological membranes
Keywords: گیرنده P2X7; P2X7 receptor; Ionic channel activity; Peptide single channel activity; Artificial planar lipid bilayer; Patch-clamp
Mechanisms of Mg2+ inhibition of BzATP-dependent Ca2+ responses in THP-1 monocytes
Keywords: گیرنده P2X7; Mg2+; Purinergic signaling; P2X7 receptor; Store-operated Ca2+-channel;
Polymyxin B increases the depletion of T regulatory cell induced by purinergic agonist
Keywords: گیرنده P2X7; PMB; polymyxin B; Treg; regulatory T cells; IL-2; interleukin 2; CD25; interleukin 2 receptor α chain; BBG; brilliant blue G; oATP; oxidized ATP; PPADS; pyridoxal-phosphate-6-azophenyl-2â²,4â²-disulfonate; NAD; nicotinamide adenine dinucleotide; BzATP;
Role of P2X7 Receptor-Mediated IL-18/IL-18R Signaling in Morphine Tolerance: Multiple Glial-Neuronal Dialogues in the Rat Spinal Cord
Keywords: گیرنده P2X7; P2X7 receptor; IL-18; glia-neuronal interaction; morphine tolerance
P2X7 receptor as a double-edged sword: Neurotrophic and neurotoxic effects
Keywords: گیرنده P2X7; ATP; endoplasmic reticulum; excitotoxicity; mitochondria; neuron; P2X7 receptor; proliferation;
Adipocyte P2X7 receptors expression: A role in modulating inflammatory response in subjects with metabolic syndrome?
Keywords: گیرنده P2X7; P2X7 receptor; Adipocyte; Inflammation; Metabolic syndrome; Inflammasome;
Dysregulation of the inflammatory response to the parasite, Toxoplasma gondii, in P2X7 receptor-deficient mice
Keywords: گیرنده P2X7; Toxoplasma gondii; Apicomplexa; P2X7 receptor; Nitric oxide; IL-10; Immunopathology;
Opposite effects of P2X7 and P2Y2 nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells
Keywords: گیرنده P2X7; α-CTF; α-cleaved carboxyterminal fragment of APP (also known as C83); Aβ; amyloid-β peptide; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease; APP; amyloid precursor protein; BACE; β-secretase; BBG; brilliant blue G; BzATP; 2â²(3â
Expression and function of P2X7 receptor and CD39/Entpd1 in patients with type 2 diabetes and their association with biochemical parameters
Keywords: گیرنده P2X7; CD39/Entpd1; P2X7 receptor; Inflammation; CD62L; IL-1β; Immune regulation
The effect of anions on the human P2X7 receptor
Keywords: گیرنده P2X7; ATP4-; free form of ATP, not bound to cations; hP2X7R; human purinergic P2X7 receptor; P2 purinergic receptor; P2X receptor; P2X7 receptor; Patch clamp; Anion; Single channel;
P2X7 receptor-deficient mice are susceptible to bone cancer pain
Keywords: گیرنده P2X7; Bone cancer pain; P2X7 receptor; IL-1β;
ERK1/2 activation is involved in the neuroprotective action of P2Y13 and P2X7 receptors against glutamate excitotoxicity in cerebellar granule neurons
Keywords: گیرنده P2X7; Granule neurons; P2Y13 receptor; P2X7 receptor; ERK; PI3kinase; Neuroprotection; A-438079; 3-(5-(2,3-dicholorophenyl)-1H-tetrazol-1-yl) methyl pyridine; BDNF; brain derived neurotrophic factor; BBG; brilliant blue G; BzATP; 2â²(3â²)-O-(4-benzoylbenzoyl)
Microglia: Proliferation and activation driven by the P2X7 receptor
Keywords: گیرنده P2X7; Microglia; P2X7 receptor; Activation; Proliferation; Neuroinflammation
Peripheral mechanisms underlying the essential role of P2X7 receptors in the development of inflammatory hyperalgesia
Keywords: گیرنده P2X7; Mechanical inflammatory hyperalgesia; P2X7 receptor; ATP; Carrageenan; Cytokine;
Expression and function of the P2X7 purinergic receptor in patients with systemic lupus erythematosus and rheumatoid arthritis
Keywords: گیرنده P2X7; P2X7 receptor; SNPs; Autoimmunity; Apoptosis; CD62L; IL-1β
Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions
Keywords: گیرنده P2X7; Affective mood disorder; P2X7 receptor; Single nucleotide polymorphism; Receptor function; Structural modelling
Effects of protons on macroscopic and single-channel currents mediated by the human P2X7 receptor
Keywords: گیرنده P2X7; ATP4−, free form of ATP, not bound to cations; BzATP, 2′3′-O-(4-benzoyl)-benzoyl-ATP; hP2X7R, human purinergic P2X7 receptor; Vh, holding potentialP2 purinergic receptor; P2X7 receptor; pH dependence; Patch clamp
Synthesis and structure–activity relationships of pyrazolodiazepine derivatives as human P2X7 receptor antagonists
Keywords: گیرنده P2X7; IL-1β; Privileged structure; Pyrazolodiazepine; P2X7 Receptor
Possible involvement of PPARγ in the regulation of basal channel opening of P2X7 receptor in cultured mouse astrocytes
Keywords: گیرنده P2X7; P2X7 receptor; Astrocyte; YO-PRO-1; ATP; PPARγ
[3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors
Keywords: گیرنده P2X7; ATP; P2X7 receptor; IL-1beta; Gila; Radioligand binding; Pain; Inflammation; BzATP; 2â²(3â²)-O-(4-benzoylbenzoyl)adenosine 5â²-triphosphate triethylammonium salt; ATP; adenosine 5â²-triphosphate disodium salt; PPADS; pyridoxal phosphate-6-azophenyl-2â
Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders
Keywords: گیرنده P2X7; P2X7 receptor; P2X7 receptor KO mice; Depression; Anxiety; Pro-inflammatory cytokines
Functional decreases in P2X7 receptors are associated with retinoic acid-induced neuronal differentiation of Neuro-2a neuroblastoma cells
Keywords: گیرنده P2X7; ATP; Basal [Ca2+]i; Neuronal differentiation; Neuroblastoma cells; P2X7 receptor; Retinoic acid
Synthesis and structure–activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor
Keywords: گیرنده P2X7; P2X7 receptor; Tyrosine-based antagonists; Ethidium bromide uptake; IL-1β release
Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist
Keywords: گیرنده P2X7; P2X7 receptor; P2Z receptor; ATP; Protein tyrosine kinase; Lymphocyte; Erythrocyte; Human; Canine
Species and agonist dependent zinc modulation of endogenous and recombinant ATP-gated P2X7 receptors
Keywords: گیرنده P2X7; ATP; P2X7 receptor; Zinc; Copper; Mouse
Expression and function of the P2X7 receptor in rat C6 glioma cells
Keywords: گیرنده P2X7; Rat C6 glioma cells; P2X7 receptor; Calcium imaging; Migration; BzATP; OxATP
P2X7 receptors mediate NADH transport across the plasma membranes of astrocytes
Keywords: گیرنده P2X7; NADH; NAD+; Astrocyte; Transport; P2X7 receptor; Brain
P2X7 receptor mediated phosphorylation of p38MAP kinase in the hippocampus
Keywords: گیرنده P2X7; P2X7 receptor; p38MAP kinase; Western blotting; Glutamate; Release; P2X7R−/−; Knockout; Hippocampus; ATP
P2X7-induced apoptosis decreases by aging in mice myeloblasts
Keywords: گیرنده P2X7; Bone marrow; Myeloblasts; Apoptosis; Aging; P2X7 receptor
Oxygen/glucose deprivation increases the integration of recombinant P2X7 receptors into the plasma membrane of HEK293 cells
Keywords: گیرنده P2X7; Apoptosis; Cationic channel; Ischemia; Pore dilation; P2X7 receptor; Receptor trafficking
Oxidized ATP decreases β-actin expression and intracellular superoxide concentrations in RBA-2 type-2 astrocytes independently of P2X7 receptor
Keywords: گیرنده P2X7; P2X7 receptor; Oxidized ATP; Astrocytes; β-actin; RBA-2 astrocytes
P2X7 receptors exert a permissive role on the activation of release-enhancing presynaptic α7 nicotinic receptors co-existing on rat neocortex glutamatergic terminals
Keywords: گیرنده P2X7; P2X7 receptor; α7 nicotinic receptor; Glutamate release; Nicotine; Superfused synaptosomes; Rat neocortex
P2X7 receptor-mRNA and -protein in the mouse retina; changes during retinal degeneration in BALBCrds mice
Keywords: گیرنده P2X7; Development; Retina; Mouse; P2X7 receptor; Real-time PCR; Immunohistochemistry; Retinitis pigmentosa;
CD39-associated high ATPase activity contribute to the loss of P2X7-mediated calcium response in LCL cells
Keywords: گیرنده P2X7; ALL; acute lymphoblastic leukemia; AML; acute myelogenous leukemia; ATP; adenosine-5â²-triphosphate; BSA; bovine serum albumin; βγMeATP; β,γ-methylene ATP; BzATP; 2â²,3â²-O-(4-benzoylbenzoyl)-ATP; CML; chronic myelogenous leukemia; DEPC; diethylpyr
Inhibitory effects of U73122 and U73343 on Ca2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line
Keywords: گیرنده P2X7; Cytosolic calcium; U73122; U73343; P2X7 receptor; ATP;
Roles of protein kinase C in regulation of P2X7 receptor-mediated calcium signalling of cultured type-2 astrocyte cell line, RBA-2
Keywords: گیرنده P2X7; ATP; Adenosine 5â²-triphosphate; BzATP; 2â²-3â²-O-(4-benzoylbenzoyl)adenosine 5â²-triphosphate; Ca2+; Calcium; [Ca2+]i; Intracellular calcium concentration; PKC; Protein kinase C; PMA; Phorbol 12-myristate 13 acetate; Astrocytes; P2X7 receptor; Calciu