دانلود مقالات ISI درباره بیماری پارکینسون + ترجمه فارسی

PARP-1 involvement in neurodegeneration: A focus on Alzheimer's and Parkinson's diseases

Keywords: بیماری پارکینسون; Alzheimer's disease; Parkinson's disease; Poly(ADP-ribose)polymerase; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice

Keywords: بیماری پارکینسون; ANOVA; analysis of variance; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; IR; immunoreactivity; LPS; lipopolysaccharide; NBM; neurobasal medium; PBS; phosphate-buffered saline; PD; Parkinson's disease; PPAR; peroxisome proliferator-activated recep

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Changes in the expression of neurotransmitter receptors in Parkin and DJ-1 knockout mice - A quantitative multireceptor study

Keywords: بیماری پارکینسون; PD; Parkinson's disease; ROI; regions of interest; Parkinson's disease; neurotransmitter receptor; Parkin; DJ-1; knockout mouse;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Tanshinone IIA protects dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity through miR-153/NF-E2-related factor 2/antioxidant response element signaling pathway

Keywords: بیماری پارکینسون; 6-OHDA; 6-hydroxydopamine; ARE; antioxidant response element; BSA; bovine serum albumin; Cyt C; cytochrome c; DA; dopamine; DAPI; 4′,6-diamidino-2-phenylindole; DCFH-DA; 2′,7′-dichlorodihydrofluorescein diacetate; DMSO; dimethylsulfoxide; DOPAC; dih

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Partial depletion of the proinflammatory monocyte population is neuroprotective in the myenteric plexus but not in the basal ganglia in a MPTP mouse model of Parkinson's disease

Keywords: بیماری پارکینسون; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Enteric nervous system; Central nervous system; Inflammation; Macrophage; Microglia; Tyrosine hydroxylase; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Blockade of metabotropic glutamate receptor 5 protects against DNA damage in a rotenone-induced Parkinson's disease model

Keywords: بیماری پارکینسون; DHPG; (s)-3,5- dihydroxy-phenylglycine; DMSO; dimethylsulfoxide; ERK; extracellular signal-regulated kinase; MAPK; mitogen-activated protein kinase; mGluR5; metabotropic glutamate receptor 5; MPEP; 2-methyl-6-(phenylethynyl)pyridine; PD; Parkinson's dis

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Attenuation of neuromotor deficits by natural antioxidants of Decalepis hamiltonii in transgenic Drosophila model of Parkinson's disease

Keywords: بیماری پارکینسون; CAT; catalase; DCFH-DA; dichloro-dihydrofluorescein diacetate; LPO; lipid peroxidation; PD; Parkinson's disease; PQ; paraquat; ROS; reactive oxygen species; SDS; sodium dodecyl sulphate; SOD; superoxide dismutase; TBA; thiobarbituric acid; Drosophila me

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Striatal tyrosine hydroxylase-positive neurons are associated with l-DOPA-induced dyskinesia in hemiparkinsonian mice

Keywords: بیماری پارکینسون; 6-OHDA; 6-hydroxydopamine; AADC; aromatic acid decarboxylase; AIMs; abnormal involuntary movements; DA; dopamine; L-DOPA; L-3,4-dihydroxyphenylalanine; LID; L-DOPA-induced dyskinesia; MFB; medial forebrain bundle; NHS; normal horse serum; OD; optical dens

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Dopamine midbrain neurons in health and Parkinson's disease: Emerging roles of voltage-gated calcium channels and ATP-sensitive potassium channels

Keywords: بیماری پارکینسون; D2-AR; D2-autoreceptor; DA; dopamine; DBS; deep brain stimulation; DHPs; dihydropyridines; ER; endoplasmic reticulum; ETC; electron transfer chain; K-ATPs; ATP-sensitive potassium channels; LC; locus coeruleus; LTCCs; L-type calcium channels; mNOS; mitoch

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Sirtuin 3 regulates Foxo3a-mediated antioxidant pathway in microglia

Keywords: بیماری پارکینسون; AD; Alzheimer's disease; Cat; catalase; CNS; central nervous system; CC; corpus callosum; Foxo3a; forkhead box O 3a; LPS; lipopolysaccharide; mnSod; manganese superoxide dismutase; PD; Parkinson's disease; ROS; reactive oxygen species; Sirt 3; sirtuin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Diffusion-MRI in neurodegenerative disorders

Keywords: بیماری پارکینسون; Diffusion-MRI; Alzheimer's disease; Parkinson's disease; Amyotrophic lateral sclerosis; Huntington's disease; Degenerative ataxias;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

Combined therapy of Di-Huang-Yi-Zhi with Donepezil in patients with Parkinson's disease dementia

Keywords: بیماری پارکینسون; Di-Huang-Yi-Zhi; Donepezil; Cognitive function; Parkinson's disease; Dementia;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression

Keywords: بیماری پارکینسون; ARE; antioxidant response elements; CNC; Cap 'n' Collar; CBA; coumarin boronic acid; GCLM; glutamate-cysteine ligase modifier subunit; eGFP; enhanced green fluorescent protein; HO-1; heme oxygenase 1; iTRAQ; Isobaric tags for relative and absolute qua

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2015 سفارش ترجمه

The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease

Keywords: بیماری پارکینسون; αSyn; alpha-synuclein; ALP; autophagy/lysosomal degradation pathway; CSF; cerebral spinal fluid; ERK5; extracellular-signal-regulated kinase 5; IL; interleukin; KI; knock-in; KO; knockout; LPS; lipopolysaccharide; LRRK2; leucine rich repeat kinase 2; MHC

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2015 سفارش ترجمه

Banana (Musa spp) from peel to pulp: Ethnopharmacology, source of bioactive compounds and its relevance for human health

Keywords: بیماری پارکینسون; Musa spp; Banana peel; Bioactive compounds; Phytochemistry; Metabolomics; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

The protein l-isoaspartyl (d-aspartyl) methyltransferase protects against dopamine-induced apoptosis in neuroblastoma SH-SY5Y cells

Keywords: بیماری پارکینسون; 6-OHDA; 6-hydroxydopamine; AdoMet; S-adenosyl-l-methionine; CaPIMT1; chick pea PIMT; DA; dopamine; DMSO; dimethyl sulfoxide; gly-LDL; glycated Low-Density Lipoprotein; H2DCFDA; 2′,7′-dichlorodihydrofluorescein diacetate; MAO; monoamine oxidase; MPTP;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: بیماری پارکینسون; AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Nrf2-a therapeutic target for the treatment of neurodegenerative diseases

Keywords: بیماری پارکینسون; Nrf2; Oxidative stress; Alzheimer's disease; Parkinson's disease; Amyotrophic lateral sclerosis; Huntington's disease; Multiple sclerosis;

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Replacement of amide with bioisosteres led to a new series of potent adenosine A2A receptor antagonists

Keywords: بیماری پارکینسون; Bioisostere; Adenosine receptor; Antagonist; GPCR; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Clinical StudyNeuropsychological and psychiatric assessments following bilateral deep brain stimulation of the subthalamic nucleus in Japanese patients with Parkinson's disease

Keywords: بیماری پارکینسون; Anxiety; Cognitive function; Deep brain stimulation; Parkinson's disease; Subthalamic nucleus;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Brain SPECT can differentiate between essential tremor and early-stage tremor-dominant Parkinson's disease

Keywords: بیماری پارکینسون; Essential tremor; Parkinson's disease; Perfusion SPECT;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Maternal exposure to bisphenol A may increase the risks of Parkinson's disease through down-regulation of fetal IGF-1 expression

Keywords: بیماری پارکینسون; AMY; amygdala; AFP; alpha fetoglobulin; AKT; protein kinase B; BPA; bisphenol A; DA; dopamine; 6-OHDA; 6-OH-dopamine; DOPAC; dihydroxyphenylacetic acid; EB; embryoid body; EDC; environmental endocrine disruptors; ESCs; embryonic stem cells; FACS; fluoresc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Clinical REM sleep behavior disorder and motor subtypes in Parkinson's disease: A questionnaire-based study

Keywords: بیماری پارکینسون; Parkinson's disease; Clinical rapid eye movement sleep behavioral disorder; Tremor dominant Parkinson's disease; Non-tremor dominant Parkinson's disease; Subtypes of Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Peripheral expression of MAPK pathways in Alzheimer's and Parkinson's diseases

Keywords: بیماری پارکینسون; Alzheimer's disease; c-Jun N-terminal kinase; Mitogen-activated protein kinase; Parkinson's disease; Peripheral blood lymphocytes;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Novel and functional ABCB1 gene variant in sporadic Parkinson's disease

Keywords: بیماری پارکینسون; ABCB1; ATP-binding cassette sub-family B member 1; ATP13A2; Lysosomal P-type transmembrane cation-transporting ATPase, PARK9; BBB; Blood-brain barrier; DJ-1; PARK7 gene; DSVs; DNA sequence variants; FOXO1; Forkhead box factor O1; FOXO3a; Forkhead box fa

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

SNCA variants rs2736990 and rs356220 as risk factors for Parkinson's disease but not for amyotrophic lateral sclerosis and multiple system atrophy in a Chinese population

Keywords: بیماری پارکینسون; Parkinson's disease; Amyotrophic lateral sclerosis; Multiple system atrophy; SNCA; Polymorphisms; rs2736990; rs356220;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

1,25-Dyhydroxyvitamin D3 attenuates rotenone-induced neurotoxicity in SH-SY5Y cells through induction of autophagy

Keywords: بیماری پارکینسون; Calcitriol; Parkinson's disease; Autophagy; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes

Keywords: بیماری پارکینسون; ANS; 1-anilinonaphthalene-8-sulfonate; A4F; asymmetrical flow field-flow fractionation; αSN; α-synuclein; CD; circular dichroism; DLS; dynamic light scattering; PD; Parkinson's Disease; SDS; sodium dodecyl sulfate; SEC; size exclusion chromatography;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of mitochondrial fission attenuates Aβ-induced microglia apoptosis

Keywords: بیماری پارکینسون; AD; Alzheimer's disease; Aβ; β-amyloid protein; BALB; Bagg albino; CytC; cytochrome c; DMEM; Dulbecco's modified eagle medium; Drp1; dynamin-related protein 1; FBS; fetal bovine serum; GTP; Guanosine triphosphate; HD; Huntington's disease; Mdivi-1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Altered expression of dopamine receptors in cholinergic motoneurons of the hypoglossal nucleus in a 6-OHDA-induced Parkinson's disease rat model

Keywords: بیماری پارکینسون; PD; Parkinson's disease; SN; substantia nigra; D1; dopamine receptor 1; D2; dopamine receptor 2; HN; hypoglossal nucleus; DMV; dorsal motor nucleus of the vagus; SqRT-PCR; semi-quantitative reverse transcription and polymerase chain reaction; 6-OHDA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Impaired motor coordination in Pitx3 overexpression mice

Keywords: بیماری پارکینسون; Parkinson's disease; Pitx3; Midbrain DA neurons;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Visual cues and gait improvement in Parkinson's disease: Which piece of information is really important?

Keywords: بیماری پارکینسون; IRED; infrared light-emitting diode; MMSE; Mini Mental State Examination; PD; Parkinson's disease; UPDRS; Unified Parkinson's Disease Rating Scale; Parkinson's disease; visual cues; gait; gaze;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

ReviewMeta-analysis of the efficacy and safety of long-acting non-ergot dopamine agonists in Parkinson's disease

Keywords: بیماری پارکینسون; Extended-release pramipexole; Meta-analysis; Parkinson's disease; Ropinirole prolonged-release; Rotigotine transdermal patch;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of the root bark of Paeonia suffruticosa on mitochondria-mediated neuroprotection in an MPTP-induced model of Parkinson's disease

Keywords: بیماری پارکینسون; Paeonia suffruticosa; Parkinson's disease; Mitochondria dysfunction; MPTP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

CNB-001, a novel pyrazole derivative mitigates motor impairments associated with neurodegeneration via suppression of neuroinflammatory and apoptotic response in experimental Parkinson's disease mice

Keywords: بیماری پارکینسون; CNB-001; Parkinson's disease; Inflammation; Apoptosis; MPTP;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Research ReportNeurogranin binds α-synuclein in the human superior temporal cortex and interaction is decreased in Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; Dementia with Lewy bodies; Neurogranin; α-Synuclein; Calmodulin; LTP;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Increased striatal adenosine A2A receptor levels is an early event in Parkinson's disease-related pathology and it is potentially regulated by miR-34b

Keywords: بیماری پارکینسون; Adenosine A2A receptor; ADORA2A; miR-34b; Putamen; Parkinson's disease; Post-mortem;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Co-modulation of finely tuned high-gamma band activity across hemispheres in Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; Deep brain stimulation; Gamma frequency band; Co-modulation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold

Keywords: بیماری پارکینسون; AD; Alzheimer's disease; ANK; ankyrin repeat domain; ARM; armadillo repeat domain; AUC; area under the curve; BA; brain availability; BBB; blood brain barrier; BCRP; breast cancer related protein; BI; brain impairment; CSD; Cambridge Structural Database

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Simvastatin reverses the downregulation of M1/4 receptor binding in 6-hydroxydopamine-induced parkinsonian rats: The association with improvements in long-term memory

Keywords: بیماری پارکینسون; ABC; avidin-biotin-peroxidase complex staining system; Acb; accumbens nucleus; AD; Alzheimer's disease; AI; agranular insular cortex; Amy; amygdala; ANOVA; analysis of variance; Arc; arcuate hypothalamic nucleus; Cg; cingulate cortex; CPu; caudate p

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Gene expression regulation of Bcl2, Bax and cytochrome-C by geraniol on chronic MPTP/probenecid induced C57BL/6 mice model of Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; MPTP; Geraniol; Neuroprotective; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Automatic classification and prediction models for early Parkinson's disease diagnosis from SPECT imaging

Keywords: بیماری پارکینسون; PD; Parkinson's disease; PPMI; Parkinson's progression markers initiative; SPECT; single photon emission computed tomography; SVM; support vector machine; SBR; striatal binding ratio; Computer-aided early diagnosis; Parkinson's disease; Risk predict

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Research ReportMinocycline inhibits ICAD degradation and the NF-κB activation induced by 6-OHDA in PC12 cells

Keywords: بیماری پارکینسون; 6-Hydroxydopamine; Minocycline; Nuclear factor-κB; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 α-synuclein phosphorylation in mouse brain

Keywords: بیماری پارکینسون; ANOVA; analysis of variance; Ce; cerebellum; CEB; cell extraction buffer; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; Co; cerebral cortex; CSNK2a2; alpha prime subunit of casein kinase II; EDTA; ethylenediaminetetraacetic acid; EGTA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and SAR study of a novel series of dopamine receptor agonists

Keywords: بیماری پارکینسون; Dopamine receptor agonist; Parkinson's disease; Rotigotine;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Neuromodulation for Movement Disorders

Keywords: بیماری پارکینسون; Neuromodulation; DBS; Stereotactic surgery; Focused ultrasound; Essential tremor; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Beyond the basal ganglia: cFOS expression in the cerebellum in response to acute and chronic dopaminergic alterations

Keywords: بیماری پارکینسون; 6-OHDA; 6-hydroxydopamine; DN; dentate nucleus; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; PN; pontine nuclei; SNc; substantia nigra pars compacta; SNr; SN reticulata; STN; subtalamic nucleus; cerebellum; dopamine; halo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Two-step grafting significantly enhances the survival of foetal dopaminergic transplants and induces graft-derived vascularisation in a 6-OHDA model of Parkinson's disease

Keywords: بیماری پارکینسون; Cell transplantation; Parkinson's disease; Two-step grafting; Cell survival; Graft-derived angiogenesis;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson's disease

Keywords: بیماری پارکینسون; AAV-2; adeno-associated virus; ACSVL; Acyl-coenzyme A synthetase very long; ANOVA; analysis of variance; ALS; amyotrophic lateral sclerosis; BSA; bovine serum albumin; CDNF; cerebral dopamine neurotrophic factor; Chchd3; coiled-coil-helix-coiled-coil-heli

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists

Keywords: بیماری پارکینسون; Adenosine; A2A antagonists; Parkinson's disease; Catalepsy;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه