دانلود مقالات ISI درباره Parp + ترجمه فارسی

PARP inhibition in platinum-based chemotherapy: Chemopotentiation and neuroprotection

Keywords: Platinum chemotherapy; Neuropathy; Neuroprotection; Oxidative stress; Mitochondrial dysfunction; PARP;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

3′-Hydroxy-3,4′-dimethoxyflavone-induced cell death in human leukaemia cells is dependent on caspases and reactive oxygen species and attenuated by the inhibition of JNK/SAPK

Keywords: Apoptosis; Caspases; Cell cycle; Cytotoxicity; Flavonoids; ERKs; extracellular signal-regulated kinases; IC50; 50% inhibition of cell growth; JC-1; 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide; JNK; c-Jun N-terminal

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10

Keywords: ADP-Ribosylation; PARP; ARTD; Inhibitor; Structure-activity relationship;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Poly(ADP-ribose) polymerase-2 is a lipid-modulated modulator of muscular lipid homeostasis

Keywords: Androgen; Cholesterol; PARP; Skeletal muscle; Dihydrotestosterone;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Sec6 enhances cell migration and suppresses apoptosis by elevating the phosphorylation of p38 MAPK, MK2, and HSP27

Keywords: Sec6; p38 MAPK; MK2; HSP27; MAPK; Mitogen-activated protein kinases; MAP3K; MAPK kinase kinase; MAP2K; MAPK kinase; TAK1; TGFβ-activated kinase 1; ASK1; apoptosis signal-regulating kinase 1; MLK; mixed-lineage kinase; CREB; cAMP response element binding

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells

Keywords: Imatinib resistance; Autophagy; miR-199a-5p; miR-199b-5p; WNT2; Chronic myeloid leukemia (CML); 3-MA; 3-methyladenine; AVO; acidic vesicular organelle; CML; chronic myeloid leukemia; CQ; chloroquine; DMSO; dimethyl sulfoxide; HRP; horseradish peroxidase;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Muscle-protective effects of Schisandrae Fructus extracts in old mice after chronic forced exercise

Keywords: ANOVA; analysis of variance; A1R; adenosine A1 receptor; CAT; Catalase; DEXA; dual energy X-ray absorptiometry; DW; distilled water; GSH; Glutathione; HE; haematoxylin and eosin; HNE; hydroxynonenal; iNOS; inducible nitric oxide synthase; LDH; lactate deh

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Hexane fraction of adlay (Coix lachryma-jobi L.) testa ethanolic extract inhibits human uterine sarcoma cancer cells growth and chemosensitizes human uterine sarcoma cells to doxorubicin

Keywords: Adlay testa; Doxorubicin; MES-SA; MES-SA/Dx5; HUtSMCs; Multidrug resistance; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; AHE; the ethanoic extracts of adlay hull; ABE; the ethanoic extracts of adlay bran; ATE; the ethanoic extracts

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Novel oxindole derivatives prevent oxidative stress-induced cell death in mouse hippocampal HT22 cells

Keywords: ER stress; Ferroptosis; Oxidative stress; Oxindole; Oxytosis; Rasagiline; ATF6; activated transcription factor 6; ARE; antioxidant response element; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; Grp78; 78-kDa glucose-regulated prote

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

ROS signalling in the biology of cancer

Keywords: AEJ; alternative end joining; ALL; acute lymphoblastic leukaemia; AML; acute myeloid leukaemia; Apaf-1; apoptotic protein activating factor 1; APL; acute promyelocytic leukaemia; ASK1; apoptosis signal regulating kinase 1; Bcr-Abl; breakpoint cluster-Abel

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential

Keywords: APC/C; anaphase-promoting complex/cyclosome; ASF1; antisilencing function 1; BRAF35; BRCA2-associated factor 35; BRCA2; breast cancer 2 protein; CAF-1; chromatin assembly factor 1; CR; cysteine rich; DCIS; ductal carcinoma in situ; DNMT3B; DNA methyltrans

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats

Keywords: MeCO; methanolic root extract of Colebrookea oppositifolia; I/R; ischemia reperfusion; DPPH; 2, 2-diphenyl-L-picrylhydrazyl; FRAP; ferric reducing antioxidant power; ORAC; oxygen radical absorbance capacity; LPS; lipopolysaccharide; LC-MS/MS; liquid chrom

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Linking the biological underpinnings of depression: Role of mitochondria interactions with melatonin, inflammation, sirtuins, tryptophan catabolites, DNA repair and oxidative and nitrosative stress, with consequences for classification and cognition

Keywords: Major depressive disorder; Oxidative and nitrosative stress; Kynurenine; Aryl hydrocarbon; Immune-inflammation; Mitochondria; Pathophysiology; Melatonin; Treatment; Classification; Cognition; 3-OH-ANA; 3-hydroxyanthranillic acid; 3-OH-Kyn; 3-hydroxykynure

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Protective roles of fenofibrate against cisplatin-induced ototoxicity by the rescue of peroxisomal and mitochondrial dysfunction

Keywords: Cisplatin; Fenofibrate; NADPH Oxidase Isoforms; PPAR-α; Ototoxicity; ABR; auditory brainstem responses; ACOX1; peroxisome acyl-coenzyme A oxidase 1; ARF; acute renal failure; AKI; acute kidney injury; B-FABP; brain-type fatty acid binding protein; COX5A1

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review

Keywords: AM; Atractylodes macrocephala Koidz.; TCM; traditional Chinese medicine; UPLC; ultra-performance liquid chromatography; PDA; photo-diode array; IR; infrared spectroscopy; HS-LP-LPE; headspace liquid phase-liquid-phase extraction; GC-MS; gas chromatography

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

Immuno-modulators enhance antigen-specific immunity and anti-tumor effects of mesothelin-specific chimeric DNA vaccine through promoting DC maturation

Keywords: Mesothelin; Dendritic cell; Anti-tumor effect; Mesothelin-expressing tumor; Immunotherapy; MSLN; mesothelin; CTGF; connective tissue growth factor; TAA; tumor-associated antigen; CSF1R; colony stimulating factor 1 receptor; TME; tumor microenvironment; EG

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2018 سفارش ترجمه

JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice

Keywords: Tumor Microenvironment; Drug Development; Targeted Therapy; Pancreas; AE; anion exchanger; CA; carbonic anhydrase; GPCR; G protein-coupled receptor; GPX; glutathione peroxidase; GSH; glutathione; HCQ; hydroxychloroquine; HMGB1; high mobility group box 1;

دانلود رایگان متن کامل مقاله ISI 72 صفحه سال انتشار : 2018 سفارش ترجمه

Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)

Keywords: NASH; Nrf2; TBE-31; ACACA; acetyl-CoA carboxylase alpha; ACLY; ATP citrate lyase; ACOT7; acetyl-CoA thioesterase 7; ACOX2; acetyl-CoA oxidase 2; ADRP; adipose differentiation-related protein; AP-1; activator protein 1; ApoB; apolipoprotein B; ATF4; activa

دانلود رایگان متن کامل مقاله ISI 79 صفحه سال انتشار : 2018 سفارش ترجمه

Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein

Keywords: Ubiquitin-like domain; Papain-like protease; Macrodomain; Nucleic-acid binding domain; Innate immunity; Structural biology; 3CLpro; 3C-like protease; 3Ecto; Nsp3 ectodomain; ADPr; ADP-ribose; ADRP; ADP-ribose-1″-phosphate phosphatase; ARTD; ADP-ribosylt

دانلود رایگان متن کامل مقاله ISI 87 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension

Keywords: ADRF; adipocyte-derived relaxing factor; AE; anion exchanger; ATP; adenosine triphosphate; BH4; tetrahydrobiopterin; BKCa; big conductance Ca2+-sensitive K+ channel; CaM; calmodulin; cAMP; cyclic adenosine monophosphate; CAT; cysteine aminotransferase; CB

دانلود رایگان متن کامل مقاله ISI 88 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents

Keywords: 1,4-Diaryl-2-azetidinone; Combretastatin A-4; Tubulin polymerization; Antitumor; SAR; structure-activity relationship; DABCO; 1,4-diazabicyclo[2.2.2]octane; TBAF; tetrabutylammonium fluoride; NMO; 4-methylmorpholine N-oxide; TBAB; tetrabutylammonium bromi

دانلود رایگان متن کامل مقاله ISI 91 صفحه سال انتشار : 2018 سفارش ترجمه

Clinical benefits and pharmacology of scutellarin: A comprehensive review

Keywords: Aβ; β-amyloid peptide; ACE; angiotensin-converting enzyme; AD; Alzheimer's disease; ADE; adverse drug effect; ADR; adverse drug reaction; AIF; apoptosis-inducing factor; Akt; protein kinase B or PKB; ALS; amyotrophic lateral sclerosis; AMPK; AMP-activat

دانلود رایگان متن کامل مقاله ISI 116 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of Rad51 sensitizes breast cancer cells with wild-type PTEN to olaparib

Keywords: PTEN; Phosphatase and tensin homologue; PARP; poly(ADP-ribose) polymerase; PI3K; PI3 kinase; RPA1; replication protein A1; DSB; double-strand breaks; HR; homologous recombination; SSB; single strand breaks; γH2AX; Phospho-histone H2AX; PMSF; phenylmethyl

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Design and synthesis of potent inhibitors of the mono(ADP-ribosyl)transferase, PARP14

Keywords: PARP; PARP14; ARTD-8; Mono(ADP-ribosyl) transferase;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Impact of primary platinum-free interval and BRCA1/2 mutation status on treatment and survival in patients with recurrent ovarian cancer

Keywords: BRCA1/2; Ovarian cancer; PARP; Platinum-free interval;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Investigation of XRCC1 Arg399Gln, Arg280His, and Arg194Trp polymorphisms effects on the induction of micronucleus by Aflatoxin B1 in in vitro

Keywords: AFB1; Aflatoxin B1; CBMN; Cytokinesis-blocked micronucleus; PCR-RFLP; Polymerase chain reaction restriction fragment length polymorphism; MN; Micronucleus; SCE; Sister chromatid exchange; CA; Chromosome aberrations; PARP; Poly-ADP-ribose polymerase; SNP;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Redox regulation of proteasome function

Keywords: Abcd1; ATP binding cassette subfamily D member 1; AD; Alzheimer's disease; ALD; adrenoleukodystrophy; ALS; amyotrophic lateral sclerosis; AP-1; activator protein-1; APP; amyloid precursor protein; CNS; central nervous system; DDI; DNA-damage inducible 1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

microRNA-143 acts as a suppressor of hemangioma growth by targeting Bcl-2

Keywords: miR-143; microRNA-143; HemECs; hemangioma-derived endothelial cells; VEGFR1; VEGF receptor-1; UTR; untranslated region; EBM-2; Endothelial Basal Medium-2; FBS; fetal bovine serum; qRT-PCR; Quantitative real-time polymerase chain reaction; MTT; 3-(4,5-dime

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

RNA polymerase II pausing and transcriptional regulation of the HSP70 expression

Keywords: HSP; heat shock protein; HSF1; heat shock factor 1; Pol II; RNA polymerase II; UPR; unfolded protein response; HSE; heat shock element; P-TEFb; positive transcription elongation factor b; PARP; poly(ADP)-ribose polymerase; PAF1; polymerase associated fact

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

AHR toxicity and signaling: Role of TIPARP and ADP-ribosylation

Keywords: Aryl hydrocarbon receptor; 2,3,7,8-Tretrachlorodibenzo-p-dioxin; ADP-ribosylation; TCDD-inducible poly-ADP-ribose polymerase; AHR; aryl hydrocarbon receptor; AHRE; AHR response element; ARH; ADP-ribosyl hydrolases; ARNT; AHR nuclear translocator; ARTD; AD

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

DATS sensitizes glioma cells to TRAIL-mediated apoptosis by up-regulation of death receptor 5 via ROS

Keywords: DATS; TRAIL; Apoptosis; ROS; p53; DR5; DATS; diallyl trisulfide; ROS; reactive oxygen species; NAC; N-acetyl-cysteine; PAGE; polyacrylamide gel electrophoresis; PARP; poly (ADP-ribose) polymerase; PBS; phosphate-buffered saline; SDS; sodium dodecyl sulfat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Cell fate regulation by chromatin ADP-ribosylation

Keywords: ARTD; PARP; Chromatin; Histone; ADP-ribosylation; Differentiation; Pluripotency;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

DNA Repair in Prostate Cancer: Biology and Clinical Implications

Keywords: Prostate cancer; DNA repair; PARP; BRCA; Personalized medicine; DNA damage;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Oldenlandia diffusa suppresses metastatic potential through inhibiting matrix metalloproteinase-9 and intercellular adhesion molecule-1 expression via p38 and ERK1/2 MAPK pathways and induces apoptosis in human breast cancer MCF-7 cells

Keywords: OD; Oldenlandia diffusa; MMP; matrix metalloproteinase; ICAM-1; intercellular adhesion molecule-1; MOD; methanol extracts of OD; BOD; buthanol extracts of OD; PMA; phorbol myristate acetate; ECM; extracellular matrix; PARP; ADP-ribose polymerase; FBS; fat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Polycyclic xanthones via pH-switched biotransformation of α-mangostin catalysed by horseradish peroxidase exhibited cytotoxicity against hepatoblastoma cells in vitro

Keywords: HRP; horseradish peroxidase; MMP; mitochondrial membrane potential; PARP; poly-(ADP-ribose)-polymerase; ROS; reactive oxygen species; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinases; p38; p

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Cold-inducible protein RBM3 protects neuroblastoma cells from retinoic acid-induced apoptosis via AMPK, p38 and JNK signaling

Keywords: AICAR; 5-Aminoimidazole-4-carboxamide ribonucleotide; AMPK; 5′ AMP-activated protein kinase; DMSO; dimethylsulfoxide; MTT; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide; PARP; poly (ADP-ribose) polymerase; RA; retinoic acid; RBM3; RNA-bi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Unveiling the non-repair face of the Base Excision Repair pathway in RNA processing: A missing link between DNA repair and gene expression?

Keywords: AP-site; apurinic/apyrimidinic site; APE1; apurinic/apyrimidinic endonuclease 1; BER; Base Excision Repair; DDR; DNA damage response; miRNA; microRNA; ncRNA; non coding RNA; NIR; Nucleotide Incision Repair; PARP; poly(ADP-ribose) polymerase; RBP; RNA bind

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of Lonicera caerulea berry extract on lipopolysaccharide-induced toxicity in rat liver cells: Antioxidant, anti-inflammatory, and anti-apoptotic activities

Keywords: LPS; lipopolysaccharide; NF-κB; nuclear factor-kappa B; TNF-α; tumour necrosis factor-alpha; IL; interleukin; AST; aspartate aminotransferase; ALT; alanine aminotransferase; AChE; acetylcholine esterase; PARP; poly ADP-ribose polymerase; Bcl-2; B-cell l

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleSilencing of the mRNA-binding protein HuR increases the sensitivity of colorectal cancer cells to ionizing radiation through upregulation of caspase-2

Keywords: Apoptosis; Caspase-2; Colorectal carcinoma cells; HuR; Radiotherapy resistance; CRC; colorectal cancer; DDR; DNA-damage response; HuR; human antigen R; PARP; poly ADP-ribose polymerase; 5′UTR; 5′-untranslated region;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

MC37, a new mono-carbonyl curcumin analog, induces G2/M cell cycle arrest and mitochondria-mediated apoptosis in human colorectal cancer cells

Keywords: NF-κB; nuclear factor kaapa B; CDK1; cyclin-dependent kinase 1; MMP; mitochondrial membrane potential; CRC; colorectal cancer; DMEM; Dulbecco's modified Eagle's medium; PMSF; phenylmethylsulfonylfluoride; S.D.; standard deviation; PARP; poly-ADP Ribose p

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Chlamydia trachomatis Prevents Apoptosis Via Activation of PDPK1-MYC and Enhanced Mitochondrial Binding of Hexokinase II

Keywords: EB; elementary body; RB; reticulate bodies; PI3K; phosphatidylinositol 3-kinase; HKII; hexokinase II; VDAC; voltage-dependent anion channel; CTL2; Chlamydia trachomatis L2; p.i.; post-infection; TNF-α; tumor necrosis factor-α; PARP; poly-(ADP-ribose) po

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Orobol derivatives and extracts from Cudrania tricuspidata fruits protect against 6-hydroxydomamine-induced neuronal cell death by enhancing proteasome activity and the ubiquitin/proteasome-dependent degradation of α-synuclein and synphilin-1

Keywords: 6-OHDA; 6-hydroxydomamine; PD; Parkinson's disease; PARP; poly (ADP-ribose) polymerase; ROS; reactive oxygen species; UPP; ubiquitin-proteasome pathway; UPS; ubiquitin-proteasome system; CTE50; 50% ethanol extract from Cudrania tricuspidata fruits; OB;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Pharbitis Nil (PN) induces apoptosis and autophagy in lung cancer cells and autophagy inhibition enhances PN-induced apoptosis

Keywords: PN; Pharbitis Nil; ERK1/2; Extracellular signal-regulated kinases 1 and 2; STAT3; Signal transducer and activator of transcription 3, RT-PCR, Reverse transcriptase -polymerase chain reaction; siRNA; Small interfering RNA; PARP; poly ADP-ribose polymerase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Rebamipide reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ43-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells

Keywords: Aβ; amyloid-beta; AD; Alzheimer's disease; ADAM; a disintegrin and metalloproteinase; APP; amyloid precursor protein; ASPD; amylospheroids; BCA; bicinchoninic acid; BACE1; β-site APP-cleaving enzyme-1; BDNF; brain-derived neurotrophic factor; BSA; bov

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Calebin A, a novel component of turmeric, suppresses NF-κB regulated cell survival and inflammatory gene products leading to inhibition of cell growth and chemosensitization

Keywords: Cancer; Calebin A; Apoptosis; Inflammation; NF-κB; CSC; Cigarette smoke condensate; NF-κB; Nuclear factor-kappaB; PMA; Phorbol myristate acetate; OA; Okadaic acid; COX-2; cyclooxygenase-2; PARP; Poly (ADP-ribose) polymerase; LPS; Lipopolysaccharide; IAP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Combination strategy of PARP inhibitor with antioxidant prevent bioenergetic deficits and inflammatory changes in CCI-induced neuropathy

Keywords: Chronic constriction injury; Quercetin; 4-ANI; PARP; Oxidative stress; Bioenergetic crisis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation

Keywords: IR; X-ray irradiation; MN; micronuclei; NA; nicotinic acid; PARP; poly(ADP-ribose) polymerase; PAR; poly(ADP-ribose); PBMC; human peripheral blood mononuclear cells; PHA-L; leucoagglutinin; Human peripheral blood mononuclear cells (PBMC); NAD+; DNA repair

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells

Keywords: CDDP; cisplatin; Chk1; checkpoint kinase 1; Chk2; checkpoint kinase 2; γ-H2AX; phosphorylated histone H2AX at Ser 139; LA-12; (OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloroplatinum(IV); PARP; poly (ADP-ribose) polymerase; PBS; phosphate-buffered

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Scandenolone, a natural isoflavone derivative from Cudrania tricuspidata fruit, targets EGFR to induce apoptosis and block autophagy flux in human melanoma cells

Keywords: Baf A1; bafilomycin A1; CQ; chloroquine; 3-MA; 3-methyladenine; DARTS; drug affinity responsive target stability; EGFR; epidermal growth factor receptor; PARP; poly (ADP-ribose) polymerase; PI; propidium iodide; Apoptosis; Autophagy flux; EGFR; Scandenolo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

PARP, transcription and chromatin modeling

Keywords: ABCA1; ATP-binding cassette transporter A1; ADP-ribosylation; adenosine diphosphate ribosylation; ALC1; amplified in-liver-cancer 1; AR; androgen receptor; ARH3; ADP-ribosylhydrolase 3; ART; ADP-ribosyl transferase; ASF/SF2; alternative splicing factor/sp

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه