دانلود مقالات ISI درباره Parp + ترجمه فارسی

Castalagin and vescalagin purified from leaves of Syzygium samarangense (Blume) Merrill & L.M. Perry: Dual inhibitory activity against PARP1 and DNA topoisomerase II

Keywords: PARP1 inhibitor; Castalagin; Vescalagin; Olaparib; Topoisomerase; Syzygium samarangense; PARP; poly(ADP-ribose) polymerase; PAR; poly(ADP-ribose); PARylation; poly(ADP-ribosyl)ation; PARylate; poly(ADP-ribosyl)ate; ADP-ribose; ADPR; nicotinamide; Nam; CAS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Long Noncoding RNA AK123483 is Involved in the Regulation of Myocardial Ischaemia-Reperfusion Injury by Targeting PARP and Caspase-3

Keywords: LncRNA AK123483; Myocardial IRI; A/R; LDH; PARP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Overexpression of COPS3 promotes clear cell renal cell carcinoma progression via regulation of Phospho-AKT(Thr308), Cyclin D1 and Caspase-3

Keywords: COPS3; The third subunit of the COP9 signalosome; ccRCC; clear cell renal cell carcinoma; qRT-PCR; quantitative real-time PCR; CCK-8; Cell Counting Kit-8; CSN; COP9 signalosome; COP; constitutive photomorphogenesis; siRNA; small interfering RNA; FBS; Feta

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

RBM17 controls apoptosis and proliferation to promote Glioma progression

Keywords: Glioma; RBM17; Proliferation; FAS; Apoptosis; SPF45; Splicing Factor 45; RBM17; RNA-binding motif protein 17; FAS; Fas cell surface death receptor; GBM; glioblastoma; PARP; poly ADP-ribose polymerase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Perfluorooctane sulphonate induces oxidative hepatic damage via mitochondria-dependent and NF-κB/TNF-α-mediated pathway

Keywords: PFOS; Oxidative stress; Hepatotoxicity; NF-κB/TNF-α; ALT; alanine aminotransferase; AST; aspartate transaminase; APAP; acetaminophen; BSA; bovine serum albumin; CAT; catalase; Cyt c; cytochrome c; DCFDA; 2,7-dichlorofluorescein diacetate; DMSO; dimethyl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Protective effect of Lespedeza cuneata ethanol extract on Bisphenol A-induced testicular dysfunction in vivo and in vitro

Keywords: LCE; Lespedeza cuneata ethanol extract; BPA; bisphenol A; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; PARP; Poly (ADP-ribose) polymerase; hs-CRP; high-sensitivity C-reactive protein; GOT; glutamic oxaloacetic transaminase; GPT; glutamic pyr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Lithium chloride attenuates mitomycin C induced necrotic cell death in MDA-MB-231 breast cancer cells via HMGB1 and Bax signaling

Keywords: TNBC; triple negative breast cancer; MMC; mitomycin C; HMGB1; high mobility group B1; AO/EtBr; acridine orange/ethidium bromide; HRP-IgG; horseradish peroxidase conjugated imonoglobin G; PAGE; polyacrylamide gel electrophoresis; SDS; sodium dodecyl sulfat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Doxorubicin resistance in breast cancer: A novel role for the human protein AHNAK

Keywords: cCasp7; cleaved caspase 7; cPARP; cleaved PARP; CRU; central repeated unit; DMEM; Dulbecco's Modified Eagle Medium; DXR; doxorubicin; EMT; epithelial-mesenchymal transition; FITC; fluorescein isothiocyanate; HBSS; Hank's Balanced Salt Solution; HD-DXR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Knockdown of NUP160 inhibits cell proliferation, induces apoptosis, autophagy and cell migration, and alters the expression and localization of podocyte associated molecules in mouse podocytes

Keywords: CCK-8; Cell Counting Kit-8; FBS; fetal bovine serum; FSGS; focal segmental glomerulosclerosis; HRP; horseradish peroxidase; IFN-γ; interferon-γ; LSD; least significant difference; Nup160; nucleoporin 160 kDa; OD; optical density; PARP; poly (ADP-ribos

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2

Keywords: PARP; Poly-ADP ribsose; Macrodomain; Inhibitor Design;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Enhanced Repair of UV-Induced DNA Damage by 1,25-Dihydroxyvitamin D3 in Skin Is Linked to Pathways that Control Cellular Energy

Keywords: 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 2-dG; 2-deoxy-d-glucose; 8-oxo-dG; 8-oxo-2′-deoxyguanosine; Akt; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; CPD; cyclobutane pyrimidine dimer; Δψm; mitochondrial membrane potential; ECAR; e

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Bicuculline Reverts the Neuroprotective Effects of Meloxicam in an Oxygen and Glucose Deprivation (OGD) Model of Organotypic Hippocampal Slice Cultures

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATF4; activating transcription factor 4; BIC; OGD 30 min followed by 24 h of normoxic conditions, both of them in the presence of bicuculline; CA1; Cornu ammonis 1; CCD; charge-coupled device;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

The radiotherapy-sensitization effect of cantharidin: Mechanisms involving cell cycle regulation, enhanced DNA damage, and inhibited DNA damage repair

Keywords: Pancreatic cancer; Cantharidin; Cell cycle; DNA damage repair; Radiotherapy; PP2A; protein phosphatase 2A; MTT; methyl thiazolyl tetrazolium; DMSO; dimethyl sulfoxide; NER; nucleotide excision repair; BER; base excision repair; MMR; mismatch repair; DSB;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib

Keywords: PARP; PARG; Tankyrase; Radiosensitization; Homologous recombination; Non-homologous end-joining;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Oxidants produced by methylglyoxal-modified collagen trigger ER stress and apoptosis in skin fibroblasts

Keywords: AGE; Advanced glycation end product; ATF4; Activating transcription factor 4; BID; BH3 interacting-domain death agonist; CHOP; CCAAT-enhancer-binding protein homologous protein; COL1A1; Collagen type I α1-chain; DAPI; 4',6-diamidino-2-phenylindole; ECM;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Polyphenol-rich blue honeysuckle extract alleviates silica particle-induced inflammatory responses and macrophage apoptosis via NRF2/HO-1 and MAPK signaling

Keywords: Blue honeysuckle; Polyphenol; Lung inflammation; Macrophage; Inflammatory cytokine; Antioxidant; BALF; bronchoalveolar lavage fluid; BAX; B-cell lymphoma 2-associated X protein; BH; blue honeysuckle; BHE; blue honeysuckle extract; C3G; cyanidin-3-glucosid

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Cratoxylum formosum ssp. pruniflorum activates the TRAIL death receptor complex and inhibits topoisomerase I

Keywords: Bax; Bcl-2 associated X protein; Bcl-2; B cells lymphoma-2 protein; Bid; Bcl-2 homology interacting domain death against; CFP; Cratoxylum formosum (Jack.) Dyer ssp. pruniflorum (Kurz) Gogel; DISC; Death inducing signaling complex; FADD; Fas associated dea

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Association of CASP3 genetic polymorphisms rs1049216, rs2705897 and rs4647603 with the risk of prostate cancer in Galicia (NW Spain)

Keywords: PCa; prostate cancer; BMI; body mass index; PY; pack-years; OR; odds ratio; CI; confidence interval; SNP; single nucleotide polymorphism; PARP; poly-ADP ribose polymerase; CASPs; caspases; MALDI-TOF; matrix assisted laser desorption/ionization-time of fli

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

STAT3 contributes to lysosomal-mediated cell death in a novel derivative of riccardin D-treated breast cancer cells in association with TFEB

Keywords: STAT3; signal transducers and activators of transcription 3; RD-N; Riccardin D-N; CTSB; cathepsin B; LMP; lysosomal membrane permeabilization; LAMP1; lysosome associated membrane protein 1; LM-PCD; lysosomal-mediated programme of cell death; AO; acridine

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Photoactivated [Mn(CO)3Br(μ-bpcpd)]2 induces apoptosis in cancer cells via intrinsic pathway

Keywords: CORM; Carbon monoxide releasing molecule; CO/aCORM; Photoactivated MnCORM; RPMI; Rosewell Park Memorial Institute; PI; Propidium iodide; DMEM; Dulbecco's Modified Eagle Medium; MTT; (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide); OD; Optic

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Galangin's potential as a functional food ingredient

Keywords: Galangin; Propolis; Alpinia officinarum; Functional food ingredient; Polypharmacology; Flavonoid; AChE; acetylcholinesterase; AD; Alzheimer's disease; ADME; Administration, Distribution, Metabolism and Excretion; AHR; airway hyperresponsive; AhR; aryl h

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and biological evaluation of cyclopeptide GG-8-6 and its analogues as anti-hepatocellular carcinoma agents

Keywords: HCC; hepatocellular carcinoma; MDP; muramyl dipeptide; SAR; structure and activity relationship; SPPS; solid phase peptide synthesis; MeOH; methanol; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; PI; propidium iodide; VP-16; etop

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer

Keywords: Andrographolide; Andrographis paniculata; Diterpene lactone; Anticancer; Chemotherapy; Bioactive lactone; ACS; American Chemical Society; AKT; activated protein kinase; Andro; Andrographolide derivative or conjugate; AP-1; activator protein-1; Cdk; Cyclin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

Focusing on claudin-5: A promising candidate in the regulation of BBB to treat ischemic stroke

Keywords: 5α-DHP; 5α-dihydroprogestrone; ABC; ATP-binding cassette; AF6; ALL-1-fused gene from chromosome 6; ALL; acute lymphoblastic leukemia; AMPAR; amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor; Ang-1; angiopoietin-1; AP-1; activator protein-1; BBB;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

GIT2-A keystone in ageing and age-related disease

Keywords: AD; Alzheimer's disease; ArfGAP; ADP-ribosylation factor GTPase-activating proteins; AT; adipose tissue; ATM; Ataxia Telangiectasia Mutated; ATP; adenosine tri-phosphate; BRCA1; breast cancer type 1 susceptibility protein; CNS; central nervous system; D

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Integrating plant and animal biology for the search of novel DNA damage biomarkers

Keywords: ARP; actin related protein; ASK; Arabidopsis SPK1-like; At; Arabidopsis thaliana; ATAF; arabidopsis transcription activation factor; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR-interacting protein; BARD; BRCA1-associated RING

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia

Keywords: PDGFR kinase; Type II inhibitor; Kinase inhibitor; CEL; PDGFR; platelet-derived growth factor receptor; RTK; Receptor Tyrosine Kinases; ABL kinase; Abelson kinase; KIT kinase; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; RTK; receptor ty

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Ruthenium coordination compounds of biological and biomedical significance. DNA binding agents

Keywords: 2,3-dpp; 2,3-bis(2-pyridyl)pyrazine; 2-appt; 2-amino-4-phenylamino-6-(2-pyridyl)-1,3,5-triazine; apip; 2-(2-aminophenyl)imidazo[4,5-f][1,10]phenanthroline; bnbp; 2,6-bis-(6-nitrobenzimidazol-2-yl)pyridine; bpm; 2,2′-bipyrimidine; bpy; 2,2′-bipyridine;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

A cardiac glycoside HTF-1 isolated from Helleborus thibetanus Franch displays potent in vitro anti-cancer activity via caspase-9, MAPK and PI3K-Akt-mTOR pathways

Keywords: Cardiac glycoside; Anti-Cancer; Helleborus thibetanus Franch.; Apoptosis; ERK and JNK pathways; PI3K-Akt-mTOR pathway; CGs; cardiac glycosides; FEN1; flap endonuclease 1; PARP; (poly (ADP-ribose) polymerase; MAPK; mitogen-activated protein kinase; ERK1/2;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain?

Keywords: Cyclophosphamide (PubChem CID: 2907); DTIC (Dacarbazine) (PubChem CID: 5353562); GPI 15427 (PubChem CID: 11739525); Lomeguatrib (PubChem CID: 3025944); NU 1025 (PubChem CID: 63306); Temozolomide (PubChem CID: 5394); BER; base excision repair; CD2F1; hybri

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

PKM2, a potential target for regulating cancer

Keywords: PK; pyruvate kinase; HCC; hepatocellular carcinoma; FBP; fructose 1,6-bisphosphate; SAICAR; Succinyl-5-aminoimidazole-4-carboxamide-1-ribose-50-phosphate; hnRNPs; heterogeneous nuclear ribonucleoproteins; PTB; polypyrimidine tract-binding protein; NEK2; n

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-tumor effect of AZD8055 against neuroblastoma cells in vitro and in vivo

Keywords: NB; Neuroblastoma; IGF; Insulin and insulin-like growth factors; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; p70S6K; p70 ribosomal protein S6 kinase; 4E-BP1; eukaryotic translat

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Harmines inhibit cancer cell growth through coordinated activation of apoptosis and inhibition of autophagy

Keywords: Harmine; Anticancer effect; DNA damage response; Autophagy; Apoptosis; ATR; ATM and Rad3-related; CPT; camptothecin; cck-8; cell count kit-8; Chk1; checkpoint kinase 1; DOX; doxorubicin; PARP; poly (ADP-ribose) polymerase; PI; propidium iodide; UPLC-Q-TOF

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro

Keywords: Ac-DEVD-AMC; N-acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin; Ac-DEVD-CHO; N-acetyl-Asp-Glu-Val-Asp-al; Ang2; Angiopoietin-2; AR; androgen receptor; BR; brassinosteroid; CHAPS; 3[(3-cholamidopropyl)dimethylammonio]-propanesulphonic acid; DMEM; Dulbeccoâ

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer

Keywords: HAT; histone acetyltransferase; PTM; post translational modification; ROS; reactive oxygen species; PARP; poly ADP-ribose polymerase; Dox; doxycycline; TRRAP; transformation/transcription domain associated protein; p400; E1A binding protein p400; RUVBL1;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

STAT6 is a cargo of exportin 1: Biological relevance in primary mediastinal B-cell lymphoma

Keywords: DAPI; 4′,6-diamidino-2-phenylindole; DMSO; dimethylsulfoxide; FCS; foetal calf serum; HSP; heat shock protein; IB; immunoblotting; IF; immunofluorescence; IL; interleukin; JAK; Janus kinase; NES; nuclear export signal; NLS; nuclear localisation signal;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Bavachalcone from Cullen corylifolium induces apoptosis and autophagy in HepG2 cells

Keywords: C. corylifolium; Bavachalcone; Apoptosis; Cell cycle; Autophagy; CCE; Cullen corylifolium ethanol extract; HCC; hepatocellular carcinoma; NAFLD; Nonalcoholic fatty liver disease; Bax; bcl-2-associated X protein; Bcl-2; b-cell lymphoma 2; Bid; BH3 interact

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

The feedback loop of “EMMPRIN/NF-κB” worsens atherosclerotic plaque via suppressing autophagy in macrophage

Keywords: Atherosclerosis; Extracellular matrix metalloproteinase inducer; Macrophage autophagy; Nuclear factor kappa B; Vulnerable plaque; AMPK; Adenosine Monophosphate Activated Protein Kinase; ApoE −/−;  Apolipoprotein E-deficient; AS; atherosclerosis; CQ;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

DNMT1 mediated promoter methylation of GNAO1 in hepatoma carcinoma cells

Keywords: HCC; hepatic celluler cancer; GNAO1; Guanine nucleotide-binding protein α1; BSP; bisulfite sequence PCR; DAC; 5-Aza-2′-deoxycytidine; TSA; Trichostatin A; DNMT-1; DNA methyltransferase 1; TGF-β; transforming growth factor β; Src; steroid receptor cof

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer

Keywords: 7-AAD; 7-amino-actinomycin D; ABC; ATP-binding cassette; AEC; 3-amino-9-ethyl carbazole; ATD; acute toxicity determination; Atg5; autophagy protein 5; ATP; adenosine-5′-triphosphate; BCL-2; B-cell lymphoma 2; Bip/GRP78; binding immunoglobulin protein/78

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Can crosstalk between DOR and PARP reduce oxidative stress mediated neurodegeneration?

Keywords: Oxidative stress (OS); Delta opioid receptor (DOR); Poly (ADP-ribose)-polymerase1 (PARP1); Neuroprotection; Attenuation; OS; Oxidative stress; DOR; Delta opioid receptor; PARP; Poly (ADP-ribose)-polymerase; AD; Alzheimer's disease; PD; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity

Keywords: Cancer cells; PPARγ agonist; PPARγ antagonist; Therapeutic agents; Tumorigenicity; ACC; Acetyl-CoA carboxylase; AKR1B10; Alde-keto reductase 1B10; Alpha-ESA; Alpha-eleostreac acid; ACLY; ATP citrate lyase; BADGE; Bisphenol-A-diglycidyl-etter; CSCs; Canc

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Elevated phospholipase D activity in androgen-insensitive prostate cancer cells promotes both survival and metastatic phenotypes

Keywords: Prostate cancer; Prostate cancer phospholipase D; Survival; Apoptosis; Metastasis; FBS; fetal bovine serum; HA; hemagglutinin; mTOR; mammalian target of rapamycin; PA; phosphatidic acid; PARP; poly-ADP-ribose polymerase; PLD; phospholipase D;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

The chlorinated lipidome originating from myeloperoxidase-derived HOCl targeting plasmalogens: Metabolism, clearance, and biological properties

Keywords: Chlorinated lipidome; Neutrophil activation; Plasmalogens; Inflammation; ARDS; acute respiratory distress syndrome; CHOP; C/EBP homologous protein; 2-ClDCA; 2-chlorodicarboxylic acid; 2-ClFA; 2-chlorofatty acid; 2-ClFALD; 2-chlorofatty aldehyde; 2-ClFOH;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness

Keywords: Lung cancer; 20 (R)-Ginsenoside; Hypoxia; Epithelial-mesenchymal transition; Stemness; Rg3; 20 (R)-Ginsenoside Rg3; EMT; epithelial-mesenchymal transition; NSCLC; non-small cell lung cancer; HIF-1α; hypoxia induced factor-1α; EMSA; electrophoretic m

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

An in vitro analysis of the rat C6 glioma cells to elucidate the linear alkylbenzene sulfonate induced oxidative stress and consequent G2/M phase cell cycle arrest and cellular apoptosis

Keywords: C6 glioma cells; LAS; ROS; Apoptosis; Cell cycle arrest; PARP;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses

Keywords: 4-HT; 4-hydroxytamoxifen; CD; common docking; ERK; extracellular signal-regulated kinase; FRS; F-site recruitment site; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; MEK; mitogen-activated protein kinase kinase; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-di

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Impaired PARP activity in response to the β-adrenergic receptor agonist isoproterenol

Keywords: Isoproterenol; Chronic stress; PARP; DNA strand breaks; DNA repair;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

ZH-1 enhances the anticancer activity of gemcitabine via deoxyribonucleotide synthesis and apoptotic pathway against A549 cells

Keywords: Gemcitabine; ZH-1; Apoptosis; Deoxyribonucleotides; Intrinsic apoptotic pathway; ATCC; American Type Culture Collection; ATP; adenosine-triphosphate; ATP13C15N; trioctylamine, 1,1,2-trichlorotrifluoroethane, stable isotope labeled adenosine-13C1015N5-trip

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10

Keywords: ADP-Ribosylation; PARP; ARTD; Inhibitor; Structure-activity relationship;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه