دانلود مقالات ISI درباره Parp + ترجمه فارسی

Lipoic acid prevents acrylamide-induced neurotoxicity in CD-1 mice and BV2 microglial cells via maintaining redox homeostasis

Keywords: ACR; acrylamide; LA; lipoic acid; CNS; central nervous system; GSH; glutathione; MPO; myeloperoxidase; BDNF; brain derived neurotrophic factor; NGF; nerve growth factor; NT-3; neurotrophin-3; GFAP; glial fibrillary acidic protein; NSF; N-ethylmaleimide se

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

NAD and the aging process: Role in life, death and everything in between

Keywords: CD38; PARP; SIRTUINS; NAD+; Mitochondrial function; Aging;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells-Implications for age-related macular degeneration (AMD)

Keywords: 9-1-1 complex; complex of Rad9 Rad1 and Hus1 proteins; A2E; N-retinylidene-N-retinylethanol-amine; AtRal; all-trans retinal; AMD; age-related macular degeneration; AMPK; AMP-activated protein kinase; Atg; autophagy-related gene; ATM; ataxia-telangiectasia

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma

Keywords: OS; osteosarcoma; ROS; reactive oxygen species; 3-MA; 3-methyladenine; RA; rapamycin; NAC; NAcetyl-L-cysteine; CCK8; Cell Counting Kit-8; PARP; poly (ADPribose) polymerase; MMP; mitochondrial membrane potential; MAPK; mitogen-activated protein kinase; ERK

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors

Keywords: Tankyrase inhibitors; PARP family; Wnt/β-catenin signaling pathway; Wnt pathway disruption; Wnt-driven cancers; APC; adenomatous polyposis coli gene product; ARTD; ADP-ribosyltransferases; CK1; casein kinase 1; DMPK; drug metabolism and pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

4-Hydroxynonenal (HNE) modified proteins in metabolic diseases

Keywords: AcLDL; Acetylated low density lipoprotein; AD; Alzheimer's disease; ADH; Alcohol dehydrogenase; ADP; Adenine dinucleotide; ADPRT; ADP ribosyl-transferase; ALDH; Aldehyde dehydrogenase; Arg; Arginine; ATPase; ATP synthase; CYP2E1; P450 cytochrome 2E1; Cys;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Cyperus amuricus induces G1 arrest and apoptosis through endoplasmic reticulum stress and mitochondrial signaling in human hepatocellular carcinoma Hep3B cells

Keywords: ATF6; activating transcription factor 6; C. amuricus:; Cyperus amuricus; CDKIs; cyclin-dependent kinases inhibitors; CDKs; cyclin-dependent kinases; CHOP; C/EBP-homologous protein; DAPI; 4′,6-diamidino-2-phenylindole; eIF2α; eukaryotic initiation facto

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

CRISPR knock out CTLA-4 enhances the anti-tumor activity of cytotoxic T lymphocytes

Keywords: CRISPR-Cas9; Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9; CTLA-4; cytotoxic T-lymphocyte-associated protein 4; KO; knock out; CTL; cytotoxic T lymphocytes; TNF-α; Tumor necrosis factor-α; IFN-γ; interferon

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Cognitive deficits induced by combined exposure of stress and alcohol mediated through oxidative stress-PARP pathway in the hippocampus

Keywords: Alcohol; Memory; PARP; Restraint stress; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

MiR-126 reverses drug resistance to TRAIL through inhibiting the expression of c-FLIP in cervical cancer

Keywords: TRAIL; TNF-related apoptosis-inducing ligand; Hela-TR; TRAIL-resistant Hela; SiHa-TR; TRAIL-resistant SiHa; C-FLIP; CASP8 and FADD like apoptosis regulator; TNF-α; tumor necrosis factor-α; FasL; Fas ligand; MiR-126; microRNA-126; 3′ UTR; 3′-untransl

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Genetic variants of the DNA repair genes from Exome Aggregation Consortium (EXAC) database: significance in cancer

Keywords: AP; Apurinic/Apyrimidinic; BER; Base excision repair; dbSNP; Single Nucleotide Polymorphism database; DNA; Deoxyribonucleic acid; DSB; Double-strand break; ExAC; Exome Aggregation Consortium; FA; ;Fanconi Anemia; GGR; Global Genomic Repair; GWAS; Genome W

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolic roles of poly(ADP-ribose) polymerases

Keywords: ABCA1; ATP-binding cassette sub-family A member 1; ACACA; acetyl-CoA carboxylase alpha; ACBD3; acyl-CoA binding domain containing 3; ACLY; ATP citrate lyase; ADP; adenosine diphosphate; ADPR; ADP-ribose; AFLD; alcoholic fatty liver disease; AIF; apoptosis

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Dihydromyricetin induces mitochondria-mediated apoptosis in HepG2 cells through down-regulation of the Akt/Bad pathway

Keywords: Dihydromyricetin; HepG2 cells; Hepatocellular carcinoma; Apoptosis; Akt/Bad signaling pathway; Mitochondrial apoptotic pathway; Annexin V-FITC; Annexin V-fluorescein isothiocyanate; DHM; dihydromyricetin; DMSO; dimethyl sulfoxide; GAPDH; glyceraldehyd

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Tyroservatide-TPGS-paclitaxel liposomes: Tyroservatide as a targeting ligand for improving breast cancer treatment

Keywords: YSV; Tyroservatide; TPGS; D-alpha-tocopheryl polyethylene glycol 1000 succinate monoester; T-Lip; TPGS modified liposomes; PTX; paclitaxel; TP-Lip; TPGS modified PTX liposomes; TYP-Lip; YSV-conjugated TP-Lip; TYP-Lip (2% YSV); 2%YSV-conjugated TP-Lip; YSV

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Polysaccharides of Dendrobium officinale Kimura & Migo protect gastric mucosal cell against oxidative damage-induced apoptosis in vitro and in vivo

Keywords: DO; Dendrobium officinale Kimura & Migo; DOP; Dendrobium officinale Kimura & Migo polysaccharides; H2O2; Hydrogen peroxide; NSAIDs; Non-steroidal anti-inflammatory drugs; GSH; Glutathione; COX2; Cyclooxygenase-2; ROS; Reactive oxygen species; iNOS; Induci

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells

Keywords: Polyalthia longifolia; 16-Hydroxycleroda-3,13-dien-15,16-olide; Renal cell carcinoma; Apoptosis; AO/EB; acridine orange and ethidium bromide; Bcl-2; B cell lymphoma 2; ccRCC; clear cell renal cell carcinoma; CD; 16-hydroxycleroda-3,13-dien-15,16-olide; ER

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Activating transcription factor 6-dependent sestrin 2 induction ameliorates ER stress-mediated liver injury

Keywords: Ad; adenovirus; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATF6; activating transcription factor 6; ChIP; chromatin immunoprecipitation; CHOP; C/EBP homologous protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxid

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy

Keywords: WEEPGMLPFALURN-LCFDUXPPSA-N; PARP; HDAC; Multitarget; Drug design; Antitumor;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Poly(ADP-ribose) polymerase activity and inhibition in cancer

Keywords: Poly(ADP-ribose) polymerase; Synthetic lethality; PARP; DNA repair; PARP inhibitors;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells

Keywords: BCA; bicinchoninic acid; Cyt c; cytochrome c; DAPI; 4′,6-diamidino-2-phenylindole; DCFH/DA; 2′,7′-dichlorodihydrofluorescein diacetate; DMSO; dimethylsulfoxide; FBS; Fetal bovine serum; HKII; hexokinase II; LDHA; lactate dehydrogenase; MMP; mitochon

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Liqustri lucidi Fructus inhibits hepatic injury and functions as an antioxidant by activation of AMP-activated protein kinase in vivo and in vitro

Keywords: AMPK; LKB1; Ligustri lucidi Fructus; Liver injury; CCl4; ACC; acetyl-CoA carboxylase; AICAR; aminoimidazole-carboxamide-β-d-ribofuranoside; AMPK; AMP-activated protein kinase; FACS; fluorescence-activated cell sorter; GSH; glutathione; H&E; hematoxylin a

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

NAP1L1 regulates NF-κB signaling pathway acting on anti-apoptotic Mcl-1 gene expression

Keywords: NF-κB; nuclear factor-κB; Bcl-2; B cell lymphoma protein 2; Bcl-xl; Bcl-2-related protein long form of Bcl-x; Mcl-1; myeloid cell leukemia 1; Bax; bcl-2-associated X protein; NAPs; nucleosome assembly proteins; NAP1L; NAP1 like protein; ΔΓΚζ; diacyl

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells

Keywords: 3-MA; 3-methyladenine; ADCX; 25-O-acetyl-7,8-didehydrocimigenol 3-O-beta-D-xylopyranoside; TCM; traditional Chinese medicine; HCC; hepatocellular carcinoma; ABC; ATP-binding cassette; ULK1; unc-51-like kinase 1; HCQ; hydroxychloroquine; CTSB; cathepsin B;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and biological evaluation of 4-amidobenzimidazole acridine derivatives as dual PARP and Topo inhibitors for cancer therapy

Keywords: Topo; PARP; Multitarget; Acridines; Antitumor bioactivity; KFMIMINWOVOFAL-UHFFFAOYSA-N;

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-proliferative effects of copper(II) complexes with hydroxyquinoline-thiosemicarbazone ligands

Keywords: Thiosemicarbazone; Copper(II) complex; 8-Hydroxyquinoline; Proliferation; ROS; Anticancer; ATCUN; amino-terminal copper and nickel binding; CD; circular dichroism; DMF; dimethylformamide; DMSO; dimethyl sulfoxide; Dien; diethylenetriamine; EDTA; ethylened

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2017 سفارش ترجمه

Ethanol-induced damage to the developing spinal cord: The involvement of CCR2 signaling

Keywords: ATF6; Activating transcription factor 6; CCR2; Chemokine (C-C motif) receptor 2; CHOP; C/EBP Homologous Protein; CNS; Central nervous system; DNP; Dinitrophenol; eIF2α; Eukaryotic Initiation Factor 2α; ER; Endoplasmic reticulum; FASDs; Fetal alcohol s

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2017 سفارش ترجمه

Induction of apoptosis and differentiation by atractylenolide-1 isolated from Atractylodes macrocephala in human leukemia cells

Keywords: AML; acute myeloblastic leukemia; A. macrocephula; Atractylodes macrocephula; ATL-I; atractylenolide I; CML; chronic myeloblastic leukemia; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ELISA; enzyme-linked immunosorbent assay; H

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice

Keywords: Azithromycin; drug repurposing; ischemic stroke; neuroprotection; PARP;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

The relationship between obstructive sleep apnea and intra-epidermal nerve fiber density, PARP activation and foot ulceration in patients with type 2 diabetes

Keywords: Foot ulceration; Neuropathy; Sleep apnea; Type 2 diabetes; Intra-epidermal nerve fiber density; PARP;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

A new risk locus in the ZEB2 gene for schizophrenia in the Han Chinese population

Keywords: SCZ; schizophrenia; BPD; bipolar disorder; MDD; major depressive disorder; GWAS; genome wide association study; LD; linkage disequilibrium; SCID-1; Structured Clinical Interview for DSM-IV Axis 1 Disorders; PARP; Poly ADP ribose polymerase; DSM-IV; Diagno

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Research ReportPARP inhibition attenuates early brain injury through NF-κB/MMP-9 pathway in a rat model of subarachnoid hemorrhage

Keywords: SAH; subarachnoid hemorrhage; EBI; early brain injury; ICP; intracranial pressure; CBF; cerebral blood flow; BBB; blood brain barrier; PARP; poly (ADP-ribose) polymerases; NAD; nicotinamide adenine dinucleotide; AIF; apoptosis-inducing factor; MMP-9; matr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Radiosensitization by PARP inhibition to proton beam irradiation in cancer cells

Keywords: PARP; Radiosensitizer; Proton beam; Proton therapy; Particle radiation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Deep hypothermia-enhanced autophagy protects PC12 cells against oxygen glucose deprivation via a mitochondrial pathway

Keywords: DHCA; deep hypothermic circulatory arrest; DH; deep hypothermia; OGD; oxygen glucose deprivation; I/R; ischemia/reperfusion; CytC; cytochrome c; PARP; poly-ADP-ribose polymerase; PC12; a cell line derived from a pheochromocytoma of the rat adrenal medulla

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma

Keywords: Q; quercetin; BL; Burkitt's lymphoma; BCR; B cell receptor; GC; Germinal Center; EBV; Epstein-Barr virus; PI3K; phosphatidylinositol-3-kinase; AKT; AKT or protein kinase B; mTOR; mammalian target of rapamycin; BEZ235; NVP-BEZ235; I-c-Myc; c-Myc inhibi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The plant-derived triterpenoid tingenin B is a potent anticancer agent due to its cytotoxic activity on cancer stem cells of breast cancer in vitro

Keywords: Tingenone; Breast; ER stress; Chemotherapy; Malignancy; Mammosphere; Bcl2; B-cell lymphoma 2; CSC; Cancer stem cell; ccK18, M30; Caspase cleaved keratin 18; K18; Keratin 18; ATP; Adenosine-5'-triphosphate; ER; endoplasmic reticulum; PARP; Poly (ADP-ribose

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing

Keywords: Rottlerin; AMPK; mTOR; 4EBP-1; Autophagy; Protein synthesis; RPMI; Roswell Park Memorial Institute (RPMI); Becl-1; beclin-1; AMPK; AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; mTOR; mammalian target of rapamycin; raptor; regulatory-associate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

DNA maintenance following bleomycin-induced strand breaks does not require poly(ADP-ribosyl)ation activation in Drosophila S2 cells

Keywords: PARP; poly(ADP-ribose)polymerase; PARG; poly(ADP-ribose)glycohydrolase; PAR; poly(ADP-ribosyl)ation; SSB; single-strand break; DSB; double-strands break; DNA repair; DNA breaks; PARP; Poly(ADP-ribosyl)ation; PARG;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Nicotinamide adenine dinucleotide homeostasis and signalling in heart disease: Pathophysiological implications and therapeutic potential

Keywords: Heart failure; Energy metabolism; Nicotinamide adenine dinucleotide; Sirtuin; PARP; CD38Insuffisance cardiaque; Métabolisme énergétique; Nicotinamide adénine dinucléotide; Sirtuine; PARP; CD38ADP, adenosine diphosphate; ADPR, ADP-ribose; ART, ADP-ribosyl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Desmethylanhydroicaritin isolated from Sophora flavescens, shows antitumor activities in U87MG cells via inhibiting the proliferation, migration and invasion

Keywords: MAPK; mitogen activated protein kinase; PI3K; phosphoinositide 3-kinase; MMP; matrix metalloproteinase; WST-1; 2-(4-iodophenyl)-3(40nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium; DAPI; 4,6-diamidino2-phenylindole dihydrochloride hydrate; PBS; phosphat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Interferon β improves the efficacy of low dose cisplatin by inhibiting NF-κB/p-Akt signaling on HeLa cells

Keywords: Cisplatin; Interferon β; Chemosensitivity; NF-κB; Akt; PARP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

APR-246 (PRIMA-1MET) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines

Keywords: APR-246; Olaparib; p53; PARP; ROS;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer

Keywords: HNC; head and neck cancer; DCA; dichloroacetate; CDDP; cisplatin; OXPHOS; oxidative phosphorylation; PDK2; pyruvate dehydrogenase kinase 2; PDHE1α; pyruvate dehydrogenase isoform E1α; ROS; reactive oxygen species; ΔΨm; mitochondrial membrane potential

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Riccardin D-N induces lysosomal membrane permeabilization by inhibiting acid sphingomyelinase and interfering with sphingomyelin metabolism in vivo

Keywords: RD-N; Riccardin D-N; LMP; lysosomal membrane permeabilization; ASM; acid sphingomyelinase; SM; sphingomyelin; CADs; cationic amphiphilic drugs; LAMP1; lysosome associated membrane protein 1; PARP; poly (ADP-ribose) polymerase; LDH; lactate dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma

Keywords: BRCA1/2; BRCA1 or BRCA2; CDK; cyclin-dependent kinase; FBS; heat-inactivated fetal bovine serum; HGSOC; high-grade serous ovarian carcinoma; HR; homologous recombination; IP; intraperitoneal; pADPr; poly(ADP-ribose) polymer; PARP; poly(ADP-ribose) polymer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Theanine from tea and its semi-synthetic derivative TBrC suppress human cervical cancer growth and migration by inhibiting EGFR/Met-Akt/NF-κB signaling

Keywords: TBrC; ethyl 6-bromocoumarin-3-carboxylyl l-theanine; BrC; ethyl 6-bromocoumarin-3-carboxylic acid; NF-κB; nuclear factor κB; HGF; hepatocyte growth factor; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EZH2; enhancer of zeste hom

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibitory effects of Phyllanthus emblica L. on hepatic steatosis and liver fibrosis in vitro

Keywords: α-SMA; alpha-smooth muscle actin; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; CPT-1; carnitine palmitoyl transferase-1; EA; ellagic acid; FAS; fatty acid synthase; FFA; free fatty acid; HSCs; hepatic stellate cells; NAFLD; nonalcohol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Expression level of P2X7 receptor is a determinant of ATP-induced death of mouse cultured neurons

Keywords: DIV; days in vitro; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; MAP2; microtubule-associated protein 2; mPTP; mitochondrial permeability transition pore; PARP; poly(ADP-ribose)polymerase; ATP; P2X7 receptor; neu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics

Keywords: 53BP1; tumor suppressor p53 binding protein 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; Chk; checkpoint kinase; DSB; DNA double-strand break; DDR; DNA damage response; DNA-PKcs; DNA-dependent protein kinase, catalyt

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Increased matriptase zymogen activation by UV irradiation protects keratinocyte from cell death

Keywords: DTT; DL-Dithiothreitol; HAI-1; hepatocyte growth factor activator inhibitor-1; H&E; hematoxylin and eosin; mAb; monoclonal antibody; MTP KD; matriptase knockdown; NT; non-target; PARP; poly ADP ribose polymerase; PBN; N-tert-Butyl-α-phenylnitrone; ROS; r

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

TCH1036, a indeno[1,2-c]quinoline derivative, potentially inhibited the growth of human brain malignant glioma (GBM) 8401 cells via suppression of the expression of Suv39h1 and PARP

Keywords: HKMTs, Histone lysine methyltransferases; Suv39h1, Suppressor of variegation 3-9 homolog 1; PARP, Poly (ADP-ribose) polymeraseTCH1036; GBM; HKMTs; Suv39h1; PARP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه