دانلود مقالات ISI درباره Parp + ترجمه فارسی

Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics

Keywords: 53BP1; tumor suppressor p53 binding protein 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; Chk; checkpoint kinase; DSB; DNA double-strand break; DDR; DNA damage response; DNA-PKcs; DNA-dependent protein kinase, catalyt

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Indian gooseberry (Emblica officinalis Gaertn.) suppresses cell proliferation and induces apoptosis in human colon cancer stem cells independent of p53 status via suppression of c-Myc and cyclin D1

Keywords: Colon cancer; Cancer stem cells; Amla (Emblica officinalis Gaertn.) seed and pulp; Proliferation; Apoptosis; Wnt/β-catenin signalling; Trigonelline (PubChem CID: 5570); Naringin (PubChem CID: 442428); Kaempferol (PubChem CID: 5280863); Catechin (PubChem

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of high voltage nanosecond electric pulses on eukaryotic cells (in vitro): A systematic review

Keywords: nsEP; nanosecond electric pulses; FWHM; full width at half maximum; PI; propidium iodide; TB; trypan blue; EtH; ethidium homodimer; YOPRO; YO-PRO®-1 iodide; FITC; fluorescein isothiocyanate; GFP; green fluorescent protein; PEG; polyethylene glycol; PM; p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases

Keywords: Tankyrase; PARP; 2-Arylquinazolin-4-one; Wnt; Hydrophobic cavity; ADP; adenosine diphosphate; Bn; benzyl; Cbz; benzyloxycarbonyl; DMAP; 4-dimethylaminopyridine; EDC; N′-ethyl-N-3-(dimethylaminopropyl)carbodiimide; ES; electrospray; HMBC; heteronuclear m

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer

Keywords: 4E-BP-1; eukaryotic initiation factor 4E binding protein-1; ATF4; activating transcription factor 4; Bcl2; B-cell lymphoma 2; C/EBP; CAAT/enhancer binding protein; cdc-2; cyclin-dependent kinase 1 (cell division cycle protein 2); CHOP; CAAT/enhancer bindi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Resveratrol ameliorates benzo(a)pyrene-induced testicular dysfunction and apoptosis: involvement of p38 MAPK/ATF2/iNOS signaling

Keywords: AhR; aryl hydrocarbon receptor; ATF2; activating transcription factor 2; BPDE; benzo(a)pyrene-7,8-diol-9,10-epoxide; CYP11A1; cytochrome P450 11A1; CYP1A1; cytochrome P450 1A1; iNOS; inducible nitric oxide synthase; MDA; malondialdehyde; PARP; poly-ADP ri

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways

Keywords: HepG2; human hepatoblastoma; ROS; reactive oxygen species; 3-MA; 3-methyladenine; RAP; rapamycin; NAC; NAcetyl-l-cysteine; PARP; poly (ADP-ribose) polymerase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; MDC; Monodansylcadaverine; MM

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Prunus mume Sieb. et Zucc. fruit ameliorates alcoholic liver injury in mice by inhibiting apoptosis and inflammation through oxidative stress

Keywords: Prunus mume Sieb. et Zucc; Alcoholic liver injury; Hepatic apoptosis; Lipogenesis; Natural antioxidant; 4-HNE; 4-hydroxynonenal; ACC1; acetyl coenzyme A carboxylase 1; CGA; chlorogenic acid; CMFDA; 5-chloromethylfluorescein diacetate; DAPI; 4',6-diamidino

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Paeonia japonica root extract protects hepatocytes against oxidative stress through inhibition of AMPK-mediated GSK3β

Keywords: AA; arachidonic acid; ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; 4EBP-1; eIF-4E binding protein 1; FACS; fluorescence-a

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Epigallocatechin gallate and mitochondria-A story of life and death

Keywords: ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; ALT; alanine aminotransferase; AMP; adenosine monophosphate; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; ATP; adenosine triphosphate; Bax; BCL2-Associated X Protein; Bc

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells

Keywords: 3-MA; 3-Methyl adenine; AL; autolysosome; AP; autophagosome; ATG; autophagy related; Au; auranofin; Baf A1; bafilomycin A1; CCK-8; cell counting kit-8; CQ; chloroquine; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulfoxide; DTNB; 5,5'-Dithi

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Long non-coding RNA: A newly deciphered “code” in prostate cancer

Keywords: Androgen receptor; LNCaP; Biomarker; PCa; prostate cancer; ncRNA; non-coding RNAs; lncRNA; long ncRNA; miRNA; microRNA; snRNA; small nuclear RNA; siRNA; small interfering RNA; tRNA; transfer RNA; rRNA; ribosomal RNA; PCA3; PCa antigen 3; PIN; prostatic in

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Targeting succinate:ubiquinone reductase potentiates the efficacy of anticancer therapy

Keywords: TTFA; thenoyltrifluoroacetone; ROS; reactive oxygen species; PARP; poly (ADP-ribose) polymerase; OMM; outer mitochondrial membrane; NAC; N-acetylcysteine; SQR; succinate:ubiquinone oxidoreductase; SDH; succinate dehydrogenase; α-TOS; alpha-tocopheryl-suc

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Mechanism of apoptosis induction in human breast cancer MCF-7 cell by Ruviprase, a small peptide from Daboia russelii russelii venom

Keywords: Anticancer peptide; Apoptosis; Caspase-7; Mitochondrial pathway; p53; Pro-apoptotic protein; BSA; bovine serum albumin; DIC; differential interference contrast; EMEM; Eagle's minimal essential medium; GSH; cellular glutathione; HPBL; human peripheral bloo

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Stabilization of C-RAF:KSR1 complex by DiRas3 reduces availability of C-RAF for dimerization with B-RAF

Keywords: KSR; kinase suppressor of Ras; RBD; Ras binding domain; M2PK; pyruvate kinase type M2; PARP; poly(ADP-ribose) polymerase; AMPK; AMP-activated protein kinase; RAF dimerization; KSR1; Tumour suppressor DiRas3; Ras-induced transformation;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

ON 01910.Na inhibits growth of diffuse large B-cell lymphoma by cytoplasmic sequestration of sumoylated C-MYB/TRAF6 complex

Keywords: B-LCL; B-lymphoblastoid cell line; CTRL; control; C-Myb; cellular counterpart of avian myeloblastosis viral oncogene; DAPI; 4′-6-diamidino-2-phenylindole; DLBCL; diffuse large B-cell lymphoma; hnRNP; heterogeneous nuclear ribonucleoprotein; IP; immunopr

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway

Keywords: CuE; Cucurbitacin E; ECM; extracellular matrix; HSCs; Hepatic stellate cells; TNF-α; tumor necrosis factor-α; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PARP; poly ADP-ribose polymerase; MAPK; mitogen activated protein kinase; ER

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Spiro-oxindole derivative 5-chloro-4′,5′-diphenyl-3′-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro[indoline-3,2′-pyrrolidin]-2-one triggers apoptosis in breast cancer cells via restoration of p53 function

Keywords: Breast cancer; p53; Mdm2; Spiro-oxindole; Apoptosis; Caspase-9; PARP;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition on the growth of human MDA-MB-231 breast cancer cells in vitro and tumor growth in a mouse xenograft model by Se-containing polysaccharides from Pyracantha fortuneana

Keywords: Pyracantha fortuneana; Selenium-enriched polysaccharides; Breast cancer; Apoptosis; Nude mice; Se-PFPs; selenium-enriched pyracantha fortuneana (Maxim.) Li polysaccharides; HPLC; high performance liquid chromatography; LDH; lactate dehydrogenase; MTT; 3-(

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions

Keywords: H. pylori; Helicobacter pylori; CagA; cytotoxin associated antigen A; DAPI; 4-6-diamidino-2-phenylindole; ELISA; enzyme-linked immunosorbent assay; FACS; fluorescence activated cell sorting; FUTs; fucosyltransferases; FUT4; fucosyltransferase IV; HSF1; he

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Oxidative stress plays major role in mediating apoptosis in filarial nematode Setaria cervi in the presence of trans-stilbene derivatives

Keywords: Apaf; apoptotic protease activating factor; BCl-2; B-cell lymphoma 2; CED; cell-death abnormal; CM; culture media; DEC; diethyl-carbamazine citrate; DMSO; dimethyl sulfoxide; EGL; egg laying defective; EtBr; ethidium bromide; FBS; fetal bovine serum; GAPD

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2016 سفارش ترجمه

Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1)

Keywords: AMH; anti-Müllerian hormone; COX-2; cyclooxygenase-2; IL; interleukin; iNOS; inducible nitric oxide synthase; NF-κB; nuclear factor kappa-B; PARP; poly(ADP-ribose) polymerase; POF; premature ovarian failure; PPARs; peroxisome proliferator-activated rece

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2016 سفارش ترجمه

Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs

Keywords: Indirubin; Meisoindigo; Pancreatic cancer stem cell; CSC drug; LKB1 inactivation; AMPK activation; PDAC; CD133; 2-DG; 2-deoxyglucose; ACC; acetyl-CoA carboxylase; AMPK; 5′ AMP-activated protein kinase; CHK2; check point kinase 2; DM; Dorsomorphin; ESA;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis

Keywords: NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH associated protein 1; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling; MTT; 3-(4,5-di

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage

Keywords: APP; β-amyloid precursor protein; bioFET; biologically coupled field effect transistor; CASP; caspase; CCD; charge-coupled device; CHX; cycloheximide; DMEM; Dulbecco's Modified Eagle's Medium; EEA1; early endosome antigen 1; EGFP; enhanced green fluoresc

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2016 سفارش ترجمه

TDP-43/FUS in motor neuron disease: Complexity and challenges

Keywords: AD; Alzheimer's disease; Ago2; Argonaute 2; ALS; Amyotrophic lateral sclerosis; ALS/PD; amyotrophic lateral sclerosis and Parkinsonism-dementia complex; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATF3; activating transcription factor 3

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2016 سفارش ترجمه

DNA repair targeted therapy: The past or future of cancer treatment?

Keywords: DNA damage; DNA repair; Cancer; Radiation; Replication protein A; NER; nucleotide excision repair; MMR; DNA mismatch repair; BER; base excision repair; HDR; homology directed repair; FA; Fanconi anemia; HR; homologous recombination; DDR; DNA damage respon

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2016 سفارش ترجمه

A phase 1 safety study of veliparib combined with cisplatin and etoposide in extensive stage small cell lung cancer: A trial of the ECOG-ACRIN Cancer Research Group (E2511)

Keywords: Small cell; Veliparib; PARP; Phase I;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting the Fas/FasL system in Rheumatoid Arthritis therapy: Promising or risky?

Keywords: AP; activator protein; APAF; apoptosis protease activating factor; CAD; caspase-activated DNase; CHO; Chinese hamster ovary; CIA; collagen-induced arthritis; DD; death domain; DED; death effector domain; DISC; death-inducing signaling complex; DR; death r

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Coronin 1A depletion protects endothelial cells from TNFα-induced apoptosis by modulating p38β expression and activation

Keywords: TNFα; tumor necrosis factor α; HUVEC; human umbilical vein endothelial cell; HBMVEC; human brain microvascular endothelial cell; CHX; cyclohexamide; PARP; poly(ADP-ribose) polymerase; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Differential apoptotic effect and metabolism of N-acetylsphingosine and N-hexanoylsphingosine in CHP-100 human neurotumor cells

Keywords: N-acetylsphingosine; N-hexanoylsphingosine; Long-chain ceramide; Sphingosine salvage pathway; Apoptosis; C2-Cer; N-acetylsphingosine; C6-Cer; N-hexanoylsphingosine; LC-Cer; long-chain ceramide; GSLs; glycosphingolipids; GlcCer; glucosylceramide; HPTLC; hi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

The glucosylceramide synthase inhibitor PDMP sensitizes pancreatic cancer cells to MEK/ERK inhibitor AZD-6244

Keywords: MTT; 3-[4,5-dimethylthylthiazol-2-yl]-2,5 diphenyltetrazolium bromide; PDMP; d,l-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol; DMSO; dimethyl sulfoxide; FITC; fluorescein isothiocyanate; mTOR; mammalian target of rapamycin; MAPK; mitogen activat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

The rise and fall of poly(ADP-ribose): An enzymatic perspective

Keywords: PAR, poly(ADP-ribose); PARP, PAR polymerase; PARG, PAR glycohydrolase; MARG, mono-(ADP-ribose) glycohydrolase; PARylation, poly(ADP-ribosylation)Poly(ADP-ribose); PARP; PARG; MARG; ADP-ribose; DNA damage response

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

BRCA1: Beyond double-strand break repair

Keywords: BRCA1; Base-excision repair; 8oxoG; 8-oxo-guanine; 8oxodG; 8-hydroxy-2′-deoxyguanosine; AP; apurinic/apyrimidinic; APE1 (or APE1/REF1); AP-endonuclease (redox effector factor-1); ATR; ataxia telangiectasia and Rad3 related; ATM; ataxia telangiectasia mu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

DNA mismatch repair enzymes: Genetic defects and autoimmunity

Keywords: AA; aplastic anemia; ARS; aminoacyl tRNA synthetase; CMMR-D; constitutional mismatch repair-deficiency syndrome; DM; dermatomyositis; DM1; myotonic dystrophy type I; DNA-PKcs; DNA-dependent protein kinase; ELISA; enzyme-linked immunosorbent assay; HD; Hun

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells

Keywords: PD; Platycodin D; CQ; chloroquine; DMSO; dimethylsulfoxide; MTT; 3-[4,5-Dimethyl-2-thiazolyl]-2,5-diphenyltetrazolium bromide; MDC; monodansylcadaverin; ERK; extracellular signal-regulated kinase; BAF; bafilomycin A1; LC3; microtubule-associated protein 1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

GGPPS deficiency aggravates CCl4-induced liver injury by inducing hepatocyte apoptosis

Keywords: GGPPS; geranylgeranyl diphosphate synthase; GGPP; geranylgeranyl pyrophosphate; HMG-CoA; 3-hydroxy-3-methylglutarylcoenzyme A; CCl4; carbon tetrachloride; ECM; extracellular matrix; COL1A1; type I collagen; HCV; hepatitis C virus; NASH; non-alcoholic stea

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

TNF Apoptosis Protection Fraction (TAPF) prevents apoptosis induced by TNF, but not by Fas or TRAIL, via NF-κB-induced increase in cFLIP

Keywords: cFLIP; cellular FLICE-inhibitory protein; CHX; cycloheximide; DOX; doxorubicin; IAP; inhibitor of apoptosis protein; NF-κB; nuclear factor-κB; NHDF; human dermal fibroblasts; PARP; poly-ADP ribose polymerase; pI; isoelectric point; shRNA; short hairpin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Interplay between histone acetylation/deacetylation and poly(ADP-ribosyl)ation in the development of ischemic tolerance in vitro

Keywords: Ischemia tolerance; Preconditioning; NMDA; Histone acetylation/deacetylation; Poly(ADPribosyl)ation; HDAC inhibitors; HAT; histone acetyl transferase; HDAC; histone deacetylase; OGD; oxygen-glucose deprivation; SAHA; suberoylanilide hydroxamic acid; PARP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Radiosensitizing potential of Plumbagin in B16F1 melanoma tumor cells through mitochondrial mediated programmed cell death

Keywords: DCFH-DA; 2′,7′-dicholorofluorescein diacetate; Ψm; mitochondrial membrane potential; PARP; poly (ADP-ribose) polymerase; PI; propidium iodide; PLB; Plumbagin; RIPA; radioimmunoprecipitation assay; ROS; reactive oxygen species; RT; radiation; SER; sen

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Curcumin promotes apoptosis by activating the p53-miR-192-5p/215-XIAP pathway in non-small cell lung cancer

Keywords: NSCLC; non-small cell lung cancer; miR; microRNA; DMSO; dimethyl sulfoxide; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; PARP; poly ADP-ribose polymerase; TUNEL; terminal deoxynucleotidyl transferase-mediated dUTP nick end label

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells

Keywords: BSA; bovine serum albumin; Enpp3; ectonucleotide pyrophosphatase/phosphodiesterase 3; ESRD; end stage renal disease; FFA; free fatty acid; 4-HNE; 4-hydroxy-2-nonenal; HO-1; heme oxigenase-1; MCP-1; monocyte chemoattractant protein-1; 1-MNA; 1-methylnicoti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Adrenomedullin attenuates interleukin-1β-induced inflammation and apoptosis in rat Leydig cells via inhibition of NF-κB signaling pathway

Keywords: IL-1β; Interleukin-1β; NF-κB; Nuclear factor-kappa B; ADM; Adrenomedullin; DMEM; Dulbecco's modified Eagle's medium; FBS; Fetal bovine serum; DAPI; 6-Dianidino-2-phenylindole dihydrochlor; PARP; Poly adenosine diphosphate-ribose polymerase; PBS; phosph

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Erdosteine protects HEI-OC1 auditory cells from cisplatin toxicity through suppression of inflammatory cytokines and induction of Nrf2 target proteins

Keywords: AIF; apoptosis-inducing factor; Cisplatin; cis-diammine-dichloroplatinum II; Nrf2; NF-E2-related factor 2; OC; organ of Corti; PARP; poly ADP ribose polymerase; PUMA; p53-upregulated modulator of apoptosis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Silencing Daxx increases the anti-tumor activity of a TRAIL/shRNA Bcl-xL-expressing oncolytic adenovirus through enhanced viral replication and cellular arrest

Keywords: TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; Daxx; death domain-associated protein; STAT; signal transducer and activator of transcription; PI; propidium iodide; FACS; fluorescence-activated cell sorter; MTS; 3-(4,5-dimethylthiazol-2-yl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage

Keywords: CL-PAI-1; cleaved PAI-1; FL-PAI-1; full-length PAI-1; HNE; human neutrophil elastase; HuCASMCs; human carotid artery smooth muscle cells; LRP1; low density lipoprotein receptor-related protein 1; pAkt; phospho-Akt; PAI-1; plasminogen activator inhibitor-1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Ratio of phosphorylated HSP27 to nonphosphorylated HSP27 biphasically acts as a determinant of cellular fate in gemcitabine-resistant pancreatic cancer cells

Keywords: Phosphorylated HSP27; Nonphosphorylated HSP27; Gemcitabine; Pancreatic cancer; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; DR5; death receptor 5; EGFP; enhanced green fluorescence protein; XIAP; X-linked inhibitor of apoptosis; MAPK; m

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

PARP-1 inhibitor sensitizes arsenic trioxide in hepatocellular carcinoma cells via abrogation of G2/M checkpoint and suppression of DNA damage repair

Keywords: ATO; arsenic trioxide; PARP; Poly (ADP ribose) polymerase; 4AN; 4-amino-1,8-naphythalimide; HCC; hepatocellular carcinoma; ROS; reactive oxygen species; Comet assay; single cell gel electrophoresis; OTM; Olive tail moment; CCK-8; cell counting kit-8; CI;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Antiproliferative activity of the isoindigo 5′-Br in HL-60 cells is mediated by apoptosis, dysregulation of mitochondrial functions and arresting cell cycle at G0/G1 phase

Keywords: Isoindigo; Anticancer; Apoptosis; Mitochondria dysfunction; Cell cycle; CDK; 5′-Br; [(E)-1-(5′-bromo-2′-oxoindolin-3′-ylidene)-6-ethyl-2,3,6,9-tetrahydro-2,9-dioxo-1H-pyrrolo[3,2-f]quinoline-8-carboxylic acid]; ΔΨm; difference in mitochondrial t

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Protective actions of PJ34, a poly(ADP-ribose)polymerase inhibitor, on the blood-brain barrier after traumatic brain injury in mice

Keywords: BBB; blood-brain barrier; CCI; controlled cortical impact; EBD; Evans Blue dye; ECM; extracellular matrix; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; H&E; hem

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه