دانلود مقالات ISI درباره Parp + ترجمه فارسی

The palladacycle, AJ-5, exhibits anti-tumour and anti-cancer stem cell activity in breast cancer cells

Keywords: BCS; breast cancer cell; ER; oestrogen receptor; CSC; cancer stem cell; FACS; fluorescence activated cell sorting; γH2AX; gamma-histone 2AX; mTOR; mammalian/mechanistic target of rapamycin; PARP; poly(ADP-ribose) polymerase; BCL-2; B-cell lymphoma-2; Bax

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation

Keywords: ALCL; anaplastic large cell lymphoma; ALOX; lipoxygenase A; CCID; circular chemorepellent induced defect; CYP; cytochrome P450; DCM; dichloromethane extract; EROD; ethoxyresorufin-O-deethylase; HO/PI; Hoechst 33258/propidium iodide; LEC; lymph endothelial

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

ROS-dependent activation of autophagy is a critical mechanism for the induction of anti-glioma effect of sanguinarine

Keywords: AO; acridine orange; AVOs; acidic vesicular organelles; Baf A1; bafilomycin A1; Cat; Catalase; DCFH-DA; 2', 7'-dichlorodihydrofluorescin diacetate; DMEM; Dulbecco's modified essential medium; DMSO; dimethyl sulfoxide; ERK1/2; extracellular regulated

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Depletion of poly(A)-specific ribonuclease (PARN) inhibits proliferation of human gastric cancer cells by blocking cell cycle progression

Keywords: BSA; bovine serum albumin; CDK; cyclin-dependent kinase; DDR; DNA damage response; DMEM; Dulbecco's modified Eagle's medium; EEP; endonuclease-exonuclease-phosphatase; HRP; Horseradish peroxidase; HU; hydroxyl urea; M-MLV; Moloney murine leukemia viru

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Epothilone B induces human ovarian cancer OV-90 cell apoptosis via external pathway

Keywords: EpoB; Epothilone B; PTX; paclitaxel; PARP; poly(ADP-ribose) polymerase; P-gp; glycoprotein P; TRAIL; TNF-related apoptosis-inducing ligand; TUNEL; TdT-mediated dUTP Nick-End Labeling assay; Apoptosis; Epothilone B; Paclitaxel; PARP; TUNEL; TRAIL;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

CB1 cannabinoid receptor antagonist attenuates left ventricular hypertrophy and Akt-mediated cardiac fibrosis in experimental uremia

Keywords: α-SMA; α-smooth muscle actin; ANP; atrial natriuretic peptide; β-MHC; myosin heavy chain beta; BNP; brain natriuretic peptide; BW; body weight; CB1R; cannabinoid receptor type 1; CKD; chronic kidney disease; CMR; cardiac magnetic resonance; CVD; cardio

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Tranilast: A review of its therapeutic applications

Keywords: ARH; aryl hydrocarbon receptor; bFGF; basic fibroblast growth factor; cAMP; cyclic AMP; CDK; cyclin-dependent kinase; COX-2; cyclooxsygenase-2; CTGF; connective tissue growth factor; CXCL; CX chemokine ligand; CXCR; CX chemokine receptor; EMT; epithelial-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells

Keywords: AML; acute myeloid leukemia; BSA; bovine serum albumin; DCFH-DA; 2′,7′-dichlorofluorescensin diacetate; DCM; dilated cardiomyopathy; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; FZD; furazolidone; HepG2; hepatoblastoma cell line; IGF-1; insulin-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity

Keywords: NDRG2; N-myc downstream-regulated gene 2; MRFs; myogenic regulatory factors; Cdk; cyclin-dependent kinase; Rb; retinoblastoma; Myf5; myogenic factor 5; MyoD; myogenic differentiation; p27; p27 kip1; p21; p21 waf1/cip1; Akt; thymoma viral proto-oncogene; P

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting Nrf2 in healthy and malignant ovarian epithelial cells: Protection versus promotion

Keywords: Ovarian carcinogenesis; Oxidative stress; Nrf2 (NFE2L2); BRCA1; PARP inhibitor; ARE; antioxidant response element; ATF; artificial transcription factor; BER; base excision repair; CRISPR/Cas9; clustered regularly interspaced short palindromic repeats asso

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Differential contribution of key metabolic substrates and cellular oxygen in HIF signalling

Keywords: ACC; acetyl-CoA carboxylase; Akt; protein kinase B (PKB); α-KG; α-ketoglutarate; AMPK; AMP-activated protein kinase; BPTES; (bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide; DIC; differential interference contrast; DMEM; Dulbecco׳s Modifie

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition

Keywords: Methylseleninic acid (PubChem CID: 161597); Sodium selenite (PubChem CID: 24934); Cisplatin (PubChem CID: 441203); LY294002 (PubChem CID: 3973); MSA; methylseleninic acid; Se; selenium; PPP; pentose phosphate pathway; TCA; tricarboxylic acid; ROS; reactiv

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

RecQ helicases and PARP1 team up in maintaining genome integrity

Keywords: ARTD; ADP-ribosyltransferase diphtheria toxin-like; BER; base excision repair; BG; Baller-Gerold syndrome; BLM; Bloom syndrome protein; BRCT; BRCA1 C-terminus domain; BS; Bloom syndrome; CPT; camptothecin; dHJ; double Holliday junction; DSB; DNA double-st

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

The histone chaperone HJURP is a new independent prognostic marker for luminal A breast carcinoma

Keywords: Chromatin; Epigenetics; Biomarkers; Prognosis; MKI67; CENP-A; AFA; Adaptive Focused Acoustics; ASF1; anti-silencing function 1; BCSS; breast cancer specific survival; BLC; basal-like cancer; CAF-1; chromatin assembly factor 1; CENP-A; centromere protein A

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

Benzimidazole derivatives as potential dual inhibitors for PARP-1 and DHODH

Keywords: Poly (ADP-ribose) polymerase; PARP; PARP-1; Dihydroorotate dehydrogenase; DHODH; Benzimidazole;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic

Keywords: αMyHC; alpha-myosin heavy chain; LoxP; locus of crossover P1; LADMA; Levenshtein Automata based Degenerate Motif Annotator; NFA; non-deterministic finite state automata; PBS; phosphate buffered saline; %EF; percent ejection fraction; HR; heart rate; Anp;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

The abietane diterpenoid parvifloron D from Plectranthus ecklonii is a potent apoptotic inducer in human leukemia cells

Keywords: Plectranthus ecklonii; Abietane diterpenes; Parvifloron D; Cytotoxicity; Apoptosis; ERKs; extracellular signal-regulated kinases; H2-DCF-DA; 2′,7′-dichlorodihydrofluorescein diacetate; IC50; 50% inhibition of cell growth; JC-1; 5,5′,6,6′-tetrachlo

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2015 سفارش ترجمه

Acrylamide induces mitochondrial dysfunction and apoptosis in BV-2 microglial cells

Keywords: ACR; acrylamide; DAPI; 4′,6-diamidino-2-phenylindole; AO/EB; acridine orange/ethidium bromide; NAC; N-acetyl-L-cysteine; OCR; oxygen consumption rate; ECAR; extracellular acidification rate; PDH; pyruvate dehydrogenase; JNK; c-Jun N-terminal kinases; PA

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

Epstein-Barr virus Latent Membrane Protein 2A (LMP2A)-mediated changes in Fas expression and Fas-dependent apoptosis: Role of Lyn/Syk activation

Keywords: B cells; Epstein-Barr virus; Latency Membrane Protein 2A (LMP2A); B cell receptor (BCR); Lyn; Syk; Fas (CD95); Apoptosis; PARP;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular mechanisms of rosmarinic acid from Salvia miltiorrhiza in acute lymphoblastic leukemia cells

Keywords: (ALL); acute lymphoblastic leukemia; MDR; multidrug resistance; ABC; ATP binding cassette; P-gp; P-glycoprotein; ROS; reactive oxygen species; H2DCF-DA; 2′,7′-dichlorofluorescin diacetate; DCF; 2′,7′-dichlorofluorescein; PARP; poly (ADP-ribose) po

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

Histone acetyltransferase p300 is induced by p38MAPK after photodynamic therapy: the therapeutic response is increased by the p300HAT inhibitor anacardic acid

Keywords: AA; Anacardic acid; Acetyl-H3; Histone H3 acetylation; ALA; 5-Aminolevulinic acid; Ce6; Chlorin e6; ChIP; Chromatin immunoprecipitation; COX-2; Cyclooxygenase-2; DMEM; Dulbecco's modified Eagle's medium; ERK; Extracellular-signal-regulated kinase; FBS; Fe

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer

Keywords: Tumor metabolism; NAD; NAMPT; NAPRT1; Targeted agents; ATP; adenosine triphosphate; NA; nicotinic acid; NAD; nicotinamide adenine dinucleotide; (NAM); nicotinamide; NAMN; nicotinic acid mononucleotide; NAMPT; nicotinamide phosphoribosyltransferase; NAPRT1

دانلود رایگان متن کامل مقاله ISI 88 صفحه سال انتشار : 2015 سفارش ترجمه

Liquid chromatography-tandem mass spectrometric assay for the PARP inhibitor rucaparib in plasma

Keywords: AUC; area under the plasma concentration-time curve; LLOQ; lower limit of quantification; PARP; poly(ADP-ribose) polymerase; SRM; selected reaction monitoring; T1/2; elimination half-life; QC; quality control; Rucaparib; PARP inhibitor; LC-MS/MS; Plasma

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Design and synthesis of phenolic hydrazide hydrazones as potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors

Keywords: KGRAYEYPXMVIHX-IYJUZEOBSA-N; INELDYKATADCIV-ASIDMNOUSA-N; UUMIGFXUEUOTIM-ASIDMNOUSA-N; NSEIFMWJCNHVDL-ASIDMNOUSA-N; BKXBQQKGSRLELP-WDBPGAOMSA-N; CWCLCCRCYLTNRL-WDBPGAOMSA-N; XTNKJEKGCUMJAK-WDBPGAOMSA-N; NWLISMDKSKTFSU-ASIDMNOUSA-N; IPLAOLSAINWMRJ-ASIDMNOU

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Hypoxia and hypoxia mimetic cooperate to counteract tumor cell resistance to glucose starvation preferentially in tumor cells with mutant p53

Keywords: mutant p53 R175H; mutant p53 Arg 175His; wt; wild type; PARP; poly(ADP-ribose) polymerase; ROS; reactive oxygen species; Superoxide dismutase; LDHA; p53 Mutation; p53 siRNA; Hypoxia; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

IGF1R tyrosine kinase inhibitor enhances the cytotoxic effect of methyl jasmonate in endometrial cancer

Keywords: IGF1; insulin-like growth factor-1; IGF1R; IGF1 receptor; MJ; methyl jasmonate; USC; uterine serous carcinoma; MAPK; mitogen-activated protein kinase; PCNA; proliferating cell nuclear antigen; ROS; reactive oxygen species; XTT; 2,3-bis(2-methoxy-4-nitro-5

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform

Keywords: TDP1; PARP; Topoisomerases; Drug discovery; Combination therapy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Depletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatases

Keywords: PARP; poly ADP ribose polymerase; PLK1; polo-like kinase 1; PP1; protein phosphatase 1; PP2A; protein phosphatase 2A; PP6; protein phosphatase 6; Aurora A; CDK1; IK; Mitotic arrest; Protein phosphatase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Lysine methyltransferase Smyd2 suppresses p53-dependent cardiomyocyte apoptosis

Keywords: CoCl2; cobalt chloride; MI; myocardial infarction; PARP; poly ADP ribose polymerase; TUNEL; terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labeling; RB; retinoblastoma tumor suppressor; Hsp90; heat shock protein 90; pNA; chromophore p-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Structure and function of the ARH family of ADP-ribosyl-acceptor hydrolases

Keywords: MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Gαs; α-subunit of the stimulatory guanine nucleotide-binding protein; ARH; ADP-ribosyl-acceptor hydrolase; AIF; apoptosis-inducing factor; mito-PARP1cd; catalytic domain of PARP1 with a mitochondrial t

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Function of transcription factors at DNA lesions in DNA repair

Keywords: DNA repair; DSB repair; NER; Transcription factors; NR4A; PARP;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation

Keywords: GA; gambogic acid; Ver; verapamil; Ab; antibody; ER; endoplasmic reticulum; ROS; reactive oxygen species; z-VAD-FMK; carbobenzoxy-valyl-alanyl-aspartyl-(O-methyl)-fluoromethylketone; CT-like; chymotrypsin-like; DCFH-DA; 2′,7′-dichlorfluorescein-diacet

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Expression of antiviral cytokines in Crandell-Reese feline kidney cells pretreated with Korean red ginseng extract or ginsenosides

Keywords: KRG; Korean red ginseng; HuNoV; human norovirus; FCV; feline calicivirus; MNV; murine norovirus; ZAPS; zinc finger antiviral protein shorter isoform; PARP; poly (ADP-ribose) polymerase; Korean red ginseng; Ginsenoside; Antiviral; Norovirus; Mx;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The inhibition of PARP but not EGFR results in the radiosensitization of HPV/p16-positive HNSCC cell lines

Keywords: HPV; HNSCC; EGFR; PARP; Chk1; Radiosensitivity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular mechanisms of fatty acid synthase (FASN)-mediated resistance to anti-cancer treatments

Keywords: FASN; fatty acid synthase; TNF; tumor necrosis factor; PARP; Poly (ADP-ribose) polymerase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy

Keywords: PARP; Polypharmacology; Molecular dynamics; Fluorescence anisotropy; Cancer; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

B cell CLL/lymphoma 6 member B inhibits hepatocellular carcinoma metastases in vitro and in mice

Keywords: 5-Aza; 5-aza-2′-deoxycytidine; 7-AAD; 7-aminoactinomycin D; BCL6B; B cell CLL/lymphoma 6 member B; cDNA; complementary DNA; FACS; fluorescence-activated cell sorting; DMEM; Dulbecco's modified Eagle medium; HCC; hepatocellular carcinoma; HTATIP2; HIV-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Acrolein activates cell survival and apoptotic death responses involving the endoplasmic reticulum in A549 lung cells

Keywords: AFC; amino trifluorocoumarin; AKT; protein kinase B; AMC; amino methylcoumarin; ARE; antioxidant response element; ATF6; activating transcription factor-6; BAPTA-AM; 1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid tetrakis (acetoxymethyl ester); Ba

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Interaction of Leukocyte Elastase Inhibitor/L-DNase II with BCL-2 and BAX

Keywords: AIF; Apoptosis Inducing Factor; BAK; BCL-2 antagonist/killer-1; BAX; BCL-2 associated X protein; BCL-2; B cell lymphoma 2; BHK; Baby hamster kidney cells; DAPI; 4,6 di-aminidino-2-henyl indoledichloride; DMEM; Dulbecco's Modified Eagle Medium; HeLa; Henri

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Deletion of PARP-2 induces hepatic cholesterol accumulation and decrease in HDL levels

Keywords: ABCA1; adenosine triphosphate-binding cassette transporter A1; ACACA; cetyl-CoA carboxylase alpha; ACLY; ATP citrate lyase; ACOX2; acyl-CoA oxidase 2; ARTD2; ADP-ribosyl transferase diphtheria toxin-like 2; cyp51A1; cytochrome P450, family 51 subfamily A,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Armillaria mellea component armillarikin induces apoptosis in human leukemia cells

Keywords: A. mellea; Armillaria mellea; AML; acute myeloid leukemia; G. elata; Gastrodia elata; MFI; mean fluorescence intensity; MnTBAP; Mn(III)tetrakis (4-benzoic acid) porphyrin chloride; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophe

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways

Keywords: CHOP; CCAAT/enhancer-binding protein homologous protein; DR4, -5; death receptor 4, -5; ERK; extracellular signal-regulated kinase; p38 MAPK; p38 mitogen-activated protein kinase; JNK; c-Jun N-terminal kinase; PARP; poly-ADPribose polymerase; ROS; reactiv

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Advances in patient-derived tumor xenografts: From target identification to predicting clinical response rates in oncology

Keywords: PDX; patient derived xenograft; CDX; cell line derived xenograft; CRD; clinically relevant dose; TIC; tumor initiating cell; NSG; NOD scid gamma; NSCLC; non-small cell lung cancer; CSC; cancer stem cell; SOC; standard of care; MTD; maximum tolerated dose;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease

Keywords: 4E-BP1; eukaryotic initiation factor 4E binding protein 1; 6-OHDA; 6-hydroxydopamine; ACC; acetyl-CoA carboxylase; AD; Alzheimer's disease; AMPK; AMP-dependent/activated protein kinase; DAB; 3,3′-diaminobenzidine tetrachloride; DAPI; 4′,6-diamidino-2-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Opportunities for translation: Targeting DNA repair pathways in pancreatic cancer

Keywords: ATR; ATM-Rad3-related; BER; base excision repair; Chk1; checkpoint kinase 1; DDR; DNA damage response and repair; DNA-PKcs; DNA-PK catalytic subunit; DOT1L; DOT1-like; DSB; double strand break; FOLFIRINOX; folinic acid, 5-FU, irinotecan, oxaliplatin; 5-FU

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Reduced cellular Ca2+ availability enhances TDP-43 cleavage by apoptotic caspases

Keywords: ALS; amyotrophic lateral sclerosis; BAPTA-AM; 1,2-bis (o-aminophenoxy) ethane-N,N,N′,N′-tetraacetic acid acetoxymethyl ester; BSA; bovine serum albumin; CHAPS; 3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate; CoCl2; cobalt chloride; DMEM; D

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Poly (ADP-ribose) polymerase inhibition enhances trastuzumab antitumour activity in HER2 overexpressing breast cancer

Keywords: PARP; Olaparib; Rucaparib; HER2; Trastuzumab; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Sequence divergence and diversity suggests ongoing functional diversification of vertebrate NAD metabolism

Keywords: NAD metabolism; PARP; Positive selection; Pathway evolution;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts

Keywords: AIF; apoptosis-inducing factor; ΔΨ; mitochondrial transmembrane electric potential; DOX; doxorubicin; LDH; lactate dehydrogenase; OT4; On TargetPlus scrambled negative control; PARP; Poly ADP ribose polymerase; PFGE; Pulse-field Gel Electrophoresis; siR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca2 +-permeable AMPA receptors

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AP5; 2-amino-5-phosphonopentanoate; AMPK; 5′ AMP-activated protein kinase; AIF; apoptosis-inducing factor; Cyt-C; cytochrome-C; JNK; Jun N-terminal kinase; GluA1; glutamate AMPA receptor subun

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه