Keywords: Ghrelin; Growth hormone secretagogue receptor; Paclitaxel; Chemotherapy-induced peripheral neuropathy; Peripheral neuropathic pain; PC12;
مقالات ISI (ترجمه نشده)
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Keywords: BBB; blood-brain barrier; ICP-OES; inductively coupled plasma optical emission spectrometry; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PC12; pheochromocytoma cells; Dh; hydrodynamic diameter; Bipolar disorder; Chitosan nanoparticl
Keywords: Polyaniline; Biomaterials; Electrical conductivity; Biocompatibility; Electrical stimulation; aECM; artificial extracellular matrix; AFM; atomic force microscopy; ALP; alkaline phosphatase; APS; ammonium persulfate; [BMIM][BF4]; 1-butyl-3-methylimidazoliu
Keywords: Nerve growth factor; Porous silicon; PC12; Dorsal root ganglia; Controlled release; Differentiation;
Keywords: Phytoestrogens; SERM; Breast cancer cell lines; PC12; Proliferation; Differentiation;
Keywords: ActRI; activin type-I receptor; ActRII; activin type-II recepto; ALK; activin receptor-like kinase; AR; androgen receptor; BMP; bone morphogenetic protein; BMPRI; BMP type-I receptor; BMPRII; BMP type-II receptor; DBH; dopamine-β-hydroxylase; DDC; 3,4-di
Keywords: 2,4-D; dichlorophenoxyacetic acid; [35S]TBPS; [35S]tertiary-butylbicyclophosphorothionate; 3-NP; 3-nitropropionic acid; 4CL; 4-coumarate: CoA ligase; 4-O-MH; 4-O-methylhonokiol; 6-OHDA; 6-hydroxydopamine; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; AChE; acetylc
Keywords: GT; gintonin; LPA receptor; lysophosphatidic acid receptor; GPCR; G protein-coupled receptor; PC12; pheochromocytoma cell 12; [Ca2+]i; intracellular calcium concentration; Ginseng; Gintonin; LPA receptor; [Ca2+]i transient; Dopamine; Neurotransmitter rele
Keywords: Dendritic spine; Synaptic plasticity; Neurodegenerative diseases; Psychiatric disorders; Glutamate receptor; Calcium signaling; ADHD; attention deficit hypersensitive disorders; FXS; Fragile X-syndrome; CNS; central nervous system; GABA; gamma amino butyr
Keywords: ADHD; attention-deficit/hyperactivity disorder; ANOVA; analysis of variance; BSA; bovine serum albumin; CI; cell index; DHA; docosahexaenoic acid; DMEM; Dulbecco's modified Eagle medium; EPA; eicosapentaenoic acid; FBS; fetal bovine serum; Fe; iron; GLA;
Keywords: Aβ; amyloid-beta peptide; AD; Alzheimer's disease; DTT; 1,4-dithiothreitol; EGCG; epigallocatechin-3-gallate; GA; gallic acid; GSE; grape seed extract; HD; Huntington's disease; RCM-κ-CN; reduced and carboxymethylated kappa-casein; MTT; 3-[4,5-dimet
Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer
Keywords: Andrographolide; Andrographis paniculata; Diterpene lactone; Anticancer; Chemotherapy; Bioactive lactone; ACS; American Chemical Society; AKT; activated protein kinase; Andro; Andrographolide derivative or conjugate; AP-1; activator protein-1; Cdk; Cyclin
MiR-181b regulates autophagy in a model of Parkinson's disease by targeting the PTEN/Akt/mTOR signaling pathway
Keywords: Parkinson's disease; microRNA; miR-181b; PC12; PTEN/AKT/mTOR; Autophagy;
The pro-apoptotic protein Bmf co-operates with Bim and Puma in neuron death induced by β-amyloid or NGF deprivation
Keywords: Bmf; Bcl2 Modifying Factor; PUMA; p53 upregulated modulator of apoptosis; PC12; Pheochromocytoma cells; Bcl-2; B-cell lymphoma 2; BH3; Bcl-2 homology domain 3; Bim; Bcl-2 interacting mediator of cell death; Mcl-1; Myeloid cell leukemia 1; Bak; Bcl-2 antag
PCB95 and PCB153 change dopamine levels and turn-over in PC12 cells
Keywords: PCB; polychlorinated biphenyl; PCB153; 2,2â²,4,4â²,5,5â²-Hexachlorobiphenyl; PCB95; 2,2â²,3,5â²,6-pentachlorobiphenyl; PC12; rat pheochromocytoma cell line; DOPAL; 3,4-Dihydroxyphenylacetaldehyde; DOPAC; 3,4-Dihydroxyphenylacetic acid; L-DOPA; L-3,4-
A constitutively-active IKK-complex at the axon initial segment
Keywords: Axon initial segment; NF-κB; IKK 2 Kinase; Ankyrin-G; Proximity ligation assay; Axon; AIS; axon initial segment; ASA; acetyl-salicylic acid; DMEM; Dulbecco's modified Eagle media; eGFP; enhanced green-fluorescent protein; FADD; Fas-associated death dom
Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage
Keywords: ADC; apparent diffusion coefficient; ATf; apotransferrin; B-27; a medium supplement to grow neurons; BBB; blood-brain barrier; CM; conditioned medium; CM-H2DCFDA; 5-chloromethyl-2,7-dichlorodihydrofluorescein diacetate; DAPK-1; anti-death-associated prote
The genus Polygonatum: A review of ethnopharmacology, phytochemistry and pharmacology
Keywords: Aβ; Amyloid β-peptide; Ac; acetyl; AD; Alzheimer's disease; APP; Amyloid precursor protein; RAW264.7; Murine macrophage cells; Bel-7402; Human Hepatocellular Carcinoma cell line; BMSCs; Bone marrow stromal cells; ChAT; Choline acetyltransferase; DPPH;
Protection of PC12Â cells from cocaine-induced cell death by inhibiting mitochondrial permeability transition
Keywords: Cocaine; Permeability transition pore; PC12; Mitochondria; Cyclosporin A; Metformin; CRC; Ca2+ retention capacity; CsA; cyclosporin A; CypD; cyclophilin D; Pi; inorganic phosphate; PT; permeability transition; PTP; permeability transition pore; TMRM; Tetr
Permethrin pesticide induces NURR1 up-regulation in dopaminergic cell line: Is the pro-oxidant effect involved in toxicant-neuronal damage?
Keywords: PC12; Permethrin; Nurr1; Antioxidants; Redox state;
Hypoxia pretreatment and EPO-modification enhance the protective effects of MSC on neuron-like PC12Â cells in a similar way
Keywords: Mesenchymal stem cells (MSC); PC12; Erythropoietin (EPO); Hypoxia injuries;
Novel antioxidants' synthesis and their anti-oxidative activity through activating Nrf2 signaling pathway
Keywords: Antioxidant; Nrf2; GCLC; PC12;
Garcinia xanthochymus extract protects PC12 cells from H2O2-induced apoptosis through modulation of PI3K/AKT and NRF2/HO-1 pathways
Keywords: Garcinia xanthochymus; Oxidative stress; PC12; PI3K/Akt pathway; Nrf2/HO-1 signaling pathways;
Role of histone acetylation in activation of nuclear factor erythroid 2-related factor 2/heme oxygenase 1 pathway by manganese chloride
Keywords: Manganese chloride; Neurotoxicity; NF-E2-related factor 2 (Nrf2); Heme oxygenase-1(HO-1); Histone acetylation; PD; Parkinson's disease; Nrf2; erythroid 2-related factor 2; HO-1; heme oxygenase 1; ROS; reactive oxygen species; GSH; reduced glutathione; PC1
Downregulations of TRPM8 expression and membrane trafficking in dorsal root ganglion mediate the attenuation of cold hyperalgesia in CCI rats induced by GFRα3 knockdown
Keywords: TRPM8; transient receptor potential melastatin 8; CCI; chronic constriction injury; DRG; dorsal root ganglion; GFRα3; glial cell line-derived neurotrophic factor family receptor alpha3; siRNA; small interfering RNA; TRP; transient receptor potential; dsR
2,3,7,8-Tetrachlorodibenzo-p-dioxin suppress AChE activity in NGF treated PC12 cells
Keywords: AChE; Acetylcholinesterase; Dioxin; 2,3,7,8-TCDD; PC12; Neuronal differentiation; NGF; Nerve growth factor;
Protective effects of cycloartane triterpenoides from Passiflora edulis Sims against glutamate-induced neurotoxicity in PC12 cell
Keywords: Passiflora edulis Sims; Cycloartane triterpenoid; PC12; Glutamate-induced neurotoxicity;
Deep hypothermia-enhanced autophagy protects PC12 cells against oxygen glucose deprivation via a mitochondrial pathway
Keywords: DHCA; deep hypothermic circulatory arrest; DH; deep hypothermia; OGD; oxygen glucose deprivation; I/R; ischemia/reperfusion; CytC; cytochrome c; PARP; poly-ADP-ribose polymerase; PC12; a cell line derived from a pheochromocytoma of the rat adrenal medulla
Astroglioma conditioned medium increases synaptic elimination and correlates with major histocompatibility complex of class I (MHC I) upregulation in PC12Cells
Keywords: Glioma; Astrocyte; MHC I; PC12; Synapse; Plasticity;
The potential neurotoxicity of emerging tetrabromobisphenol A derivatives based on rat pheochromocytoma cells
Keywords: TBBPA derivatives; PC12; Neurotoxicity; AChE; acetylcholinesterase; Am; amiodarone; BFRs; brominated frame retardants; DA; dopamine; DMSO; dimethyl sulfoxide; DTNB; 5,5â²-dithiobis(2-nitrobenzenoic acid); ERK; extracellular signal regulated protein kinas
Ganglioside GQ1b induces dopamine release through the activation of Pyk2
Keywords: Pyk2; GQ1b; Dopamine; PC12; MAPK/ERK; Synapsin I; F-actin;
ERK5 induces ankrd1 for catecholamine biosynthesis and homeostasis in adrenal medullary cells
Keywords: ERK; extracellular signal-regulated kinase; PC12; pheochromocytoma cells; TH; tyrosine hydroxylase; ankrd1; ankyrin repeat domain 1; NGF; nerve growth factor; EGF; epidermal growth factor; bFGF; fibroblast growth factor; GAPDH; glyceraldehyde-3-phosphate
Identification of flavonoids from Flammulina velutipes and its neuroprotective effect on pheochromocytoma-12 cells
Keywords: Flammulina velutipes; Flavonoids; Characterization; Antioxidant activity; PC12; Neuroprotective effect;
Selective and differential interactions of BNN27, a novel C17-spiroepoxy steroid derivative, with TrkA receptors, regulating neuronal survival and differentiation
Keywords: Neurotrophins; Nerve growth factor (NGF); TrkA; Neurodegeneration; Neurotrophin receptors signaling; Neuronal apoptosis; Steroid; STD NMR; Molecular modeling; NGF; nerve growth factor; BDNF; brain-derived neurotrophic factor; NT-3; neurotrophin-3; CYP17;
Cytotoxicity evaluation of extracts and fractions of five marine sponges from the Persian Gulf and HPLC fingerprint analysis of cytotoxic extracts
Keywords: Marine sponges; Cytotoxicity; HeLa; PC12; MTT test
Human PLacental eXpanded (PLX) mesenchymal-like adherent stromal cells confer neuroprotection to nerve growth factor (NGF)-differentiated PC12 cells exposed to ischemia by secretion of IL-6 and VEGF
Keywords: 2D; two dimensional; 3D; three dimensional; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; FU; fluorescence unit; H2O2; hydrogen peroxide; HS; horse serum; IL-6; interleukin 6; LDH; lactate dehydrogenase
Neuroprotective effect of modified Chungsimyeolda-tang, a traditional Korean herbal formula, via autophagy induction in models of Parkinson׳s disease
Keywords: DG; modified Chungsimyeolda-tang; MYH; modified Youldahanso-tang; SCM; Sasang Constitutional Medicine; PD; Parkinson׳s disease; UPS; ubiquitin-proteasome system; ALP; autophagy-lysosomal pathway; MPP+; 1-methyl-4-phenylpyridinium; NGF; nerve growth facto
On the role of 4-hydroxynonenal in health and disease
Keywords: AD; Alzheimer's disease; ALDH; aldehyde dehydrogenase; AMI; acute myocardial infarction; ARE; antioxidant response element; CDK; cyclin-dependent kinase; CHF; chronic heart failure; DHLA; dihydrolipoic acid; ER; endoplasmic reticulum; GSH; glutathione; HL
Edaravone protected PC12 cells against MPP(+)-cytoxicity via inhibiting oxidative stress and up-regulating heme oxygenase-1 expression
Keywords: Parkinson's disease; Edaravone; PC12; 1-Methyl-4-phenylpyridinium; Oxidative stress; Heme oxygenase-1
Characterization of the human oncogene SCL/TAL1 interrupting locus (Stil) mediated Sonic hedgehog (Shh) signaling transduction in proliferating mammalian dopaminergic neurons
Keywords: Dopaminergic neurons; PC12; Cell proliferation; Stil gene expression;
Toxicity of TDCPP and TCEP on PC12 cell: Changes in CAMKII, GAP43, tubulin and NF-H gene and protein levels
Keywords: TDCPP/TCEP; PC12; Cytotoxicity; Neurotoxicity; Gene; Protein;
Aspartame-induced apoptosis in PC12 cells
Keywords: Aspartame; Apoptosis; Caspases; AIF; PC12; Cytochrome c
Trk receptors need neutral sphingomyelinase activity to promote cell viability
Keywords: BDNF; Brain-Derived Neurotrophic Factor; Cer; ceramide; CGN; cultured granule neurons; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NGF; Nerve Growth Factor; nSMase; neutral sphingomyelinase; NT; neurotrophins; SM; sphingomyelin; Sph
Molecular mechanism of 2-APB-induced Ca2+ influx in external acidification in PC12
Keywords: 2-APB; 2-aminoethoxydiphenyl borate; BTP2; N-{4-[3, 5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}-4-methyl-1, 2, 3-thiadiazole-5-carboxamide; DA; dopamine; [Ca2+]i; intracellular calcium concentration; DMSO; dimethyl sulfoxide; ECD; electrochemical detec
Screening and identification of neuroprotective compounds relevant to Alzheimer׳s disease from medicinal plants of S. Tomé e PrÃncipe
Keywords: Aβ; amyloid beta peptide; AD; Alzheimer׳s disease; APP; amyloid precursor protein; ATP; adenosine triphosphate; BBB; blood-brain barrier; CLogP; lipophilicity; CNS; Central nervous system; DMEM; Dulbecco׳s modified Eagle׳s medium; ESI; Electrospray
Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain
Keywords: BafA1; bafilomycin A1; BoNT/X; botulinum neurotoxin/serotype X; CGNs; cerebellar granule neurons; FBS; foetal bovine serum; HC; heavy chain; HC; C-terminal half of HC; HCC; C-terminal domain of the HC-fragment; HCN; N-terminal domain of the HC-fragment; H
d-β-Hydroxybutyrate inhibited the apoptosis of PC12 cells induced by H2O2 via inhibiting oxidative stress
Keywords: d-β-Hydroxybutyrate; Apoptosis; PC12; H2O2; Oxidative stress;
MAGI-1 acts as a scaffolding molecule for NGF receptor-mediated signaling pathway
Keywords: NGF; nerve growth factor; MAGI-1; membrane-associated guanylate kinase with inverted organization-1; MAGUK; membrane-associated guanylate kinase; PDZ; PSD-95/Discs Large/Zona Occludens; Trk; tropomyosin-related kinase; DMEM; Dulbecco's modified Eagle's me
The role of Src protein in the process formation of PC12 cells induced by the proteasome inhibitor MG-132
Keywords: Cy3; Â a fluorophor cyanin dye; DMEM; Â Dulbecco's Modified Eagle's Medium; DMSO; Â dimethyl-sulfoxyde; EDTA; Â ethylenediaminetetraacetic acid; EGTA; Â ethylene glycol tetraacetic acid; ERK1/2; Â extracellular signal-regulated kinase 1 and 2; H-Ras;
Regulation of α3-containing GABAA receptors in guinea-pig adrenal medullary cells by adrenal steroids
Keywords: Ab; antibody; AM; adrenal medullary; DHEAS; dehydroepiandrostedione sulfate; DMSO; dimethyl sulfoxide; GABAAR; GABAA receptor; Hepes; hydroxyethyl piperazineethanesulfonic acid; IRs; immunoreactivities; PAGE; polyacrylamide gel electrophoresis; PBS-T; pho