دانلود مقالات ISI درباره Pcaf + ترجمه فارسی

ابزارهای اپیزیونیک (نویسندگان، خوانندگان و پاک کننده ها) و پیامدهای آنها در درمان سرطان

Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy

Keywords: ADA2; Adenosine deaminase 2; ASH1L; Absent, Small, or Homeotic 1-like; BAF; BRG1 associated factor; BAH; Bromoadjacent homology; BAZ2A; Bromodomain adjacent to zinc finger domain protein 2A; BET; Bromodomain and Extra-Terminal domain; BRPF1; Bromodomain a

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2018 سفارش ترجمه

نیکوتین آمید آدنین دینوکلئوتید: یک عامل ضروری برای حفظ شنوایی در اتوکساسیون ناشی از سیس پلاتین

Nicotinamide adenine dinucleotide: An essential factor in preserving hearing in cisplatin-induced ototoxicity

Keywords: NAD+; nicotinamide adenine dinucleotide; SIRT; sirtuin; PARP; poly(ADP-ribose) polymerase; OHCs; outer hair cells; ROS; reactive oxygen species; NOX; NAD(P)H oxidases; TNF; tumor necrosis factor; RANTES; regulated on activation normal T-cell expressed and

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

تغییرات اپیگنتیک توسط فیتوشیمیایی جیره: پیامدهای تغذیه فردی

Epigenetic modifications by dietary phytochemicals: Implications for personalized nutrition

Keywords: Epigenetics; Phytochemicals; DNA-methylation; Histone-modification; miRNA; Carcinogenesis; Akt; v-akt murine thymoma viral oncogene homolog 1; AP-1; Activator Protein-1; Bax; BCL2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; Bcl-xL; B-cell lymphoma-

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2013 سفارش ترجمه

Structure based identification and biological evaluation of novel and potent inhibitors of PCAF catalytic domain

Keywords: HAT; PCAF; Structure based virtual screening; Molecular dynamics simulation; Cytotoxicity assay; Western blot;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices

Keywords: MG149; 6-Alkylsalicylate; Acetylation; Acetyltransferase inhibitor; Lung; Inflammation; HAT; histone acetyltransferase; HATi; HAT inhibitor; HDAC; histone deacetylase; PCAF; P300/CBP-associated factor; MOZ; monocytic leukemic zinc finger; COPD; chronic ob

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The expression of progesterone receptor coregulators mRNA and protein in corpus luteum and endometrium of cows during the estrous cycle

Keywords: Nuclear receptors; Progesterone receptor coregulators; PCAF; NCOR1; Endometrium; Corpus luteum;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification

Keywords: RA; rheumatoid arthritis; TNF-α; tumor necrosis factor-alpha; MCP-1; chemoattractant protein-1, also called CCL2; HAT; histone acetyltransferase; HDAC; histone deacetylase; IL; interleukin; LPS; lipopolysaccharide; ELISA; Enzyme-linked immunosorbent assa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation

Keywords: Acetylation; GCN5; Mitochondria; SIRT1; Deacetylase; PGC-1α; AMP; adenosine monophosphate; Ca2+; calcium; CBP; CREB-binding protein; Cre-MCK; creatine kinase promoter; CHO; carbohydrate; DAC; deacetylase; ETC; electron transport chain; ExT; endurance exe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewΒeta-catenin N-terminal domain: An enigmatic region prone to cancer causing mutations

Keywords: LRP; low density lipoprotein receptor related protein; ICAT; inhibitor of β-catenin and TCF; TCF; T-Cell factor; WT; wild-type; TM; truncation mutant; PCAF; p300/CBP-associated factor; PTK6; protein-tyrosine kinase 6; BCL9; B cell lymphoma 9; APC; adenom

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Acetylation of MKL1 by PCAF regulates pro-inflammatory transcription

Keywords: Transcriptional regulation; MKL1; PCAF; Acetylation;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Expression of p300 and p300/CBP associated factor (PCAF) in actinic keratosis and squamous cell carcinoma of the skin

Keywords: p300; PCAF; Skin cancer; Epithelial-mesenchymal transition; Tissue microarray

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment

Keywords: HCC; hepatocellular carcinoma; IL-6; interleukin-6; STAT3; Signal transducer and activator of transcription 3; PCAF; P300/CBP-associated factor; HATs; histone acetyltransferases; ELISA; enzyme-linked immunosorbent assay; Co-IP; co-immunoprecipitation; ChI

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells

Keywords: B cell development; DT40; Epigenetics; Gene targeting; Histone acetyltransferase; Bach2; BTB and CNC homology 2; Bcl-6; B cell lymphoma-6; Blimp-1; B lymphocyte-induced maturation protein-1; ChIP; chromatin immunoprecipitation; EBF1; early B cell factor 1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleHBx relieves chromatin-mediated transcriptional repression of hepatitis B viral cccDNA involving SETDB1 histone methyltransferase

Keywords: HBV; Hepatitis B Virus; pgRNA; pre-genomic RNA; RC-DNA; relaxed-circular HBV DNA; cccDNA; covalently closed circular HBV DNA; CBP; CREB-binding protein; PCAF; p300/CREB-binding Protein-associated Factor; H3, H4; histone 3, histone 4; HDAC1; histone deacet

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A2b adenosine signaling represses CIITA transcription via an epigenetic mechanism in vascular smooth muscle cells

Keywords: CIITA; class II transactivator; GCN5; general control of amino acid synthesis protein 5; PCAF; p300-and-CBP-associated factor; STAT1; signal transducer and activator of transcription 1; VSMC; vascular smooth muscle cell; WDR5; WD repeat-containing protein

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Reversible acetylation of Lin28 mediated by PCAF and SIRT1

Keywords: Lin28; PCAF; SIRT1; Acetylation; Protein stability;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Cutl1: A potential target for cancer therapy

Keywords: CDP; CCAAT displacement protein; HCC; human hepatocellular carcinoma; LETFs; liver-enriched transcription factors; HNF; hepatocyte nuclear factor; Shh; Sonic hedgehog; C/EBPα; CCAAT/enhancer-binding protein; MMTV; mouse mammary tumor virus; PCAF; p300/CR

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Associations of genetic variants in the transcriptional coactivators EP300 and PCAF with hepatocellular carcinoma

Keywords: EP300; PCAF; Liver cancer; Genetic susceptibility; Histone acetyltransferases

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Acetylation of sphingosine kinase 1 regulates cell growth and cell-cycle progression

Keywords: Acetylation; Cell growth; Cell-cycle progression; Sphingosine kinase 1; acetyl-CoA; acetyl coenzyme A; Ad; adenovirus; CBP; CREB-binding protein; CREB; cAMP-response element-binding protein; EGFP; enhanced green fluorescent protein; FBS; fetal bovine seru

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Histone modifications as a pathogenic mechanism of colorectal tumorigenesis

Keywords: AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Toward understanding Machado-Joseph disease

Keywords: ATXN3; ataxin-3; bZIP; basic leucine zipper motif; CBPC; REB binding protein; cDNA; complementary DNA; CHIP; C-terminus of Hsc70 interacting protein; CK2; casein kinase 2; CMV; cytomegalovirus; CNS; central nervous system; CREB; cAMP-response element bind

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

EVI1 up-regulates the stress responsive gene SIRT1 which triggers deacetylation and degradation of EVI1

Keywords: EVI1; SIRT1; PCAF; Deacetylation; CML

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors

Keywords: Histone acetyltransferase; PCAF; Database screening; Epigenetics; Pyridoisothiazolones

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase is regulated by acetylation

Keywords: GAPDH; PCAF; Acetylation; Nuclear translocation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

15-Deoxy-Δ12,14-prostaglandin J2 impairs the functions of histone acetyltransferases through their insolubilization in cells

Keywords: 15-Deoxy-Δ12,14-prostaglandin J2; 15d-PGJ2; PCAF; p300; CBP; PPARγALLM, N-acetyl-Leu-Leu-methioninal; BADGE, bisphenol A diglycidil ether; CBP, CREB (cAMP response element-binding protein) binding protein; 15d-PGJ2, 15-deoxy-Δ12,14-prostaglandin J2; GAPDH

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Multiple lysine methylation of PCAF by Set9 methyltransferase

Keywords: PCAF; Set9; Methyltransferase; Lysine methylation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones

Keywords: PCAF; Histone acetyl transferase; Acetylation; Isothiazolones

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Reactivity of isothiazolones and isothiazolone-1-oxides in the inhibition of the PCAF histone acetyltransferase

Keywords: Histone acetyltransferase; PCAF; Isothiazolone; Isothiazolone-1-oxide; Epigenetics; Antitumour

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of a second independent binding site for the pCAF acetyltransferase in adenovirus E1A

Keywords: E1A; Conserved region 3; pCAF; Transcription; CR3

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Regenerative pharmacology in the treatment of genetic diseases: The paradigm of muscular dystrophy

Keywords: MD; muscular dystrophies; DMD; duchenne muscular dystrophy; DAPC; dystrophin-associated protein complex; DGC; dystrophin-glycoprotein complex; DG; dystroglycans; SCG; sarcoglycans; nNOS; neuronal nitric oxide synthase; NO; nitric oxide; HDAC; histone deac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation

Keywords: NAD; Poly-ADP-ribosylation; Acetylation; PCAF; GCN5L; Lysine residues

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Transcriptional and subcellular regulation of the TRIP-Br family

Keywords: TRIP-Br, transcriptional regulator interacting with the PHD-bromodomain; PBS, phosphate-buffered saline; SDS-PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis; GST, glutathione S-transferase; GFP, green fluorescent protein.Bromodomain; PCAF;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

A non-isotopic in vitro assay for histone acetylation

Keywords: Non-isotopic; Acetyl-transferase assay; p300; PCAF; Histone H3; Histone H4

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Signaling mechanisms in progesterone-neurotransmitter interactions

Keywords: progesterone receptors; ligand-independent activation; signaling; reproductive behavior; protein kinases; dopamine; AF; transcription activation function; CBP; CREB-binding protein; CREB; cyclic AMP responsive element binding protein; DA; dopamine; DARPP-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Decoding Tat: the biology of HIV Tat posttranslational modifications

Keywords: HIV; Tat; Posttranslational modification; CDK9; cyclin-dependent kinase 9; GCN5; general control of amino acid synthesis 5; NAD+; nicotinamide adenine dinucleotide; nuc-1; nucleosome 1 located immediately downstream of the start of transcription at the HI

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes

Keywords: CARM1; coactivator-associated arginine methyltransferase 1; CBP; CREB binding protein; CDK; cyclin-dependent kinase; CIITA; class II transactivator; CREB; cAMP response element binding protein; HAT; histone acetyltransferase; HDAC; histone deacetylase; HM

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Sirtuins (histone deacetylases III) in the cellular response to DNA damage-Facts and hypotheses

Keywords: CBP; CREB-binding protein; DNA-PK; DNA-dependent protein kinase; DSB; DNA double strand break; FOXO; forkhead box class O; Gadd45; growth arrest and DNA damage response gene; HAT; histone acetyltransferase; HDAC; histone deacetylase; Mn-SOD; manganese sup

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Smads and chromatin modulation

Keywords: AER; apical ectodermal ridge; ACF; ATP-utilizing chromatin assembly and remodeling factor; AML; acute myeloid leukaemia; AMT; arginine methyl transferase; ARC; activator-recruited cofactor; BAF; BRG1/hBRM-associated factors; BMP; bone morphogenic protein;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2005 سفارش ترجمه