دانلود مقالات ISI درباره Pd-1 + ترجمه فارسی

Understanding the structural and energetic basis of PD-1 and monoclonal antibodies bound to PD-L1: A molecular modeling perspective

Keywords: PD-L1; PD-1; Monoclonal antibody; Molecular dynamics simulation; Virtual alanine scanning mutagenesis;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Bacterially activated B-cells drive T cell differentiation towards Tr1 through PD-1/PD-L1 expression

Keywords: Hfstim; Helicobacter felis -stimulated; Hfstim- IL-10+ B; Helicobacter felis-stimulated IL-10- producing B cells; Hfstim- IL-10-B; Helicobacter felis-stimulated IL-10- nonproducing B cells; Breg; regulatory B cells; PD-1; programmed death 1; PD-L1; pr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

CCRK is a novel signalling hub exploitable in cancer immunotherapy

Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular adjuvants that modulate regulatory T cell function in vaccination: A critical appraisal

Keywords: ADCC; antibody dependent cell cytotoxicity; CD; cluster of differentiation; mAb; monoclonal antibody; CsA; cyclosporine; CTLA-4; T-lymphocyte antigen 4; GITR; glucocorticoid-induced tumor necrosis factor receptor (TNFR) family related gene; CCR4; C-C chem

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of Patients

Keywords: miR-125; miR-148; Antitumor Immune Response; Immune Checkpoints; CTL; cytotoxic T lymphocytes; CTLA-4; cytotoxic T lymphocyte associated protein 4; EAC; esophageal adenocarcinoma; gMFI; geometric mean fluorescence intensity; HLA-A/B/C; human leukocyte ant

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Safety and Efficacy of PD-1 Inhibitors Among HIV-Positive Patients With Non-Small Cell Lung Cancer

Keywords: Lung cancer; HIV; Pembrolizumab; Nivolumab; PD-1; PD-L1; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Case-control study of PD-1, PD-L1 and B7-H3 expression in lung cancer patients with and without human immunodeficiency virus (HIV) infection

Keywords: Human immunodeficiency virus; Lung cancer; PD-1; PD-L1; B7-H3;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Epigenetic mechanisms regulating T-cell responses

Keywords: Epigenetics; gene regulation; enhancer; promoter; chromatin accessibility; histone modifications; DNA methylation; transcription factor binding; T-cell development; T-cell function; T-cell exhaustion; regulatory T cells; tissue specificity; ATAC; Assay fo

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

PD-1/PD-L1 inhibitor screening of caffeoylquinic acid compounds using surface plasmon resonance spectroscopy

Keywords: PD-1; PD-L1; Surface plasmon resonance; Caffeoylquinic acid compounds; Small-molecule inhibitors;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Novel minor HLA DR associated antigens in type 1 diabetes

Keywords: IM; Inflammatory myositis; MLH1; MutL homolog; MTIF3; Mitochondrial translational initiation factor 3; NAPPA Array; Nucleic acid programmable protein arrays; NUP50; Nucleoporin 50; PD-1; Programmed cell death protein 1; PDL1; Programmed cell death 1 ligan

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

The exhausted CD4+CXCR5+ T cells involve the pathogenesis of human tuberculosis disease

Keywords: CD4+CXCR5+ T cells; TB disease; Inhibitory receptors; Tim-3; PD-1;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

CTLA-4, PD-1 and TIM-3 expression predominantly downregulated in MS patients

Keywords: CTLA-4; PD-1; TIM-3; Multiple sclerosis;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins

Keywords: Immune checkpoint proteins (ICPs); miRNAs; Cancer immune escape; Antigen-MHC; antigen-major histocompatibility complex; ICPs; immune checkpoint proteins; 3′UTR; 3′ untransltated region; PD-1; programmed cell death protein; Tregs; regulatory T cells; H

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

PD-L1 expression in tumor cells and the immunologic milieu of bladder carcinomas: a pathologic review of 165 cases

Keywords: Bladder cancer; Urothelial carcinoma; Transitional cell carcinoma; PD-L1; PD-1; Immune checkpoint inhibitors; Immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors

Keywords: Immune Regulation; Tumor Immunosuppression; microRNA15A/16-1; Colon Cancer Model; AD; azoxymethane with dextran sodium sulfate; CAC; colitis-associated colorectal cancer; CRC; colorectal cancer; CXCL; chemokine (C-X-C motif) ligand; DSS; dextran sodium

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Prognostic Value of PD-L1 mRNA Sequencing Expression Profile in Non-Small Cell Lung Cancer

Keywords: CCLE; Cancer Cell Line Encyclopedia; GTEx; Genotype-Tissue Expression; HR; hazard ratio; IHC; immunohistochemical; NSCLC; non-small cell lung cancer; PD-1; programmed cell death protein one; PD-L1; programmed cell death protein ligand 1; OS; overall survi

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Airway exposure initiates peanut allergy by involving the IL-1 pathway and T follicular helper cells in mice

Keywords: Follicular T cells; IL-4; IgE; allergy; peanut; IL-1; IL-33; BAL; Bronchoalveolar lavage; CTX; Cholera toxin; eGFP; Enhanced green fluorescent protein; FACS; Fluorescence-activated cell sorting; GC; Germinal center; IL-1RAcP; IL-1R-associated protein; IN;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Immunomodulatory effects of BRAF and MEK inhibitors: Implications for Melanoma therapy

Keywords: Binimetinib (PubChem CID: 10288191); Cobimetinib (PubChem CID: 16222096); Dabrafenib (PubChem CID: 44462760); Encorafenib (PubChem CID: 50922675); Trametinib (PubChem CID: 11707110); Vemurafenib (PubChem CID: 42611257); ATC; adoptively transferred T cells

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain?

Keywords: Cyclophosphamide (PubChem CID: 2907); DTIC (Dacarbazine) (PubChem CID: 5353562); GPI 15427 (PubChem CID: 11739525); Lomeguatrib (PubChem CID: 3025944); NU 1025 (PubChem CID: 63306); Temozolomide (PubChem CID: 5394); BER; base excision repair; CD2F1; hybri

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

BRAF Mutant Lung Cancer: Programmed Death Ligand 1 Expression, Tumor Mutational Burden, Microsatellite Instability Status, and Response to Immune Check-Point Inhibitors

Keywords: BRAF; lung cancer; PD-1; PD-L1; immune check-point inhibitors;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of IL-10-secreting CD8+CD28−PD-1+ regulatory T cells associated with chronic hepatitis C virus infection

Keywords: CD8+CD28− regulatory T cells; HCV; PD-1; IL-10;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Correlations of PD-L1 gene polymorphisms with susceptibility and prognosis in hepatocellular carcinoma in a Chinese Han population

Keywords: HCC; Hepatocellular carcinoma; TACE; Transcatheter arterial chemoembolisation; FDA; Food and Drug Administration; OS; Overall survival; PD-1; Programmed dealth-1; PD-L1; Programmed dealth-1 ligand-1; NSCLC; Non-small cell lung cancer; SNPs; Single nucleot

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

CD8+ T cells expressing both PD-1 and TIGIT but not CD226 are dysfunctional in acute myeloid leukemia (AML) patients

Keywords: Acute myeloid leukemia; CD8+ T cells; CD226; TIGIT; PD-1; T cell dysfunction;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Dynamic changes in the immunological characteristics of T lymphocytes in surviving patients with severe fever with thrombocytopenia syndrome (SFTS)

Keywords: Severe fever with thrombocytopenia syndrome; T lymphocytes; Apoptosis; T cell proliferation; T cell activation; PD-1; T cell functionality;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Rational design and development of a peptide inhibitor for the PD-1/PD-L1 interaction

Keywords: PD-1; Peptide therapy; Immune checkpoints; CD8 T-cells;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Clinical Features and Management of Acquired Resistance to PD-1 Axis Inhibitors in 26 Patients With Advanced Non-Small Cell Lung Cancer

Keywords: PD-1; PD-L1; acquired resistance; non-small cell lung cancer; immunotherapy;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

TIGIT-Fc alleviates acute graft-versus-host disease by suppressing CTL activation via promoting the generation of immunoregulatory dendritic cells

Keywords: APC; antigen-presenting cell; BMDCs; bone marrow-derived dendritic cells; CFSE; carboxyfluorescein succinimidyl ester; CTL; cytotoxic T lymphocyte; CTLA-4; cytotoxic T lymphocyte-associated antigen-4; DCs; dendritic cells; ERK; extracellular-signal-regula

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

PD-1 Modulates Radiation-Induced Cardiac Toxicity through Cytotoxic T Lymphocytes

Keywords: PD-1; Radiation-induced cardiac toxicity; Radiotherapy; CD8; Immunotherapy; Toxicity;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

FOXOs in cancer immunity: Knowns and unknowns

Keywords: 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Analysis of spontaneous resolution of cytomegalovirus replication after transplantation in CMV-seropositive patients with pretransplant CD8+IFNG+ response

Keywords: Solid organ transplantation; Cytomegalovirus infection; T-cell response; QuantiFERON-CMV assay; Interferon-gamma; D+/D-; CMV-seropositive/CMV-seronegative donor; IFNG; interferon-gamma; mTOR; mammalian target of rapamycin; PD-1; programmed death 1; QF; Qu

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation

Keywords: Stevens-Johnson; Toxic epidermal necrolysis; HLA; Networks; Pharmacogenomics; Pharmacovigilance; Electronic health record; T cells; Granulysin; ADR; Adverse drug reaction; AMT; Amniotic membrane transplantation; BSA; Body surface area; CPNDS; Canadian Pha

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

CD103+CD8+ T lymphocytes in non-small cell lung cancer are phenotypically and functionally primed to respond to PD-1 blockade

Keywords: CD103; Non-small cell lung cancer; PD-1; IFN-γ; T-box transcription factors;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Rationale for combination of therapeutic antibodies targeting tumor cells and immune checkpoint receptors: Harnessing innate and adaptive immunity through IgG1 isotype immune effector stimulation

Keywords: ADCC; Cetuximab; CTLA-4; PD-L1; PD-1; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Increased Coexpression of PD-1, TIGIT, and KLRG-1 on Tumor-Reactive CD8+ T Cells During Relapse after Allogeneic Stem Cell Transplantation

Keywords: MiHA; Allo-SCT; PD-1; TIGIT and T cells;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Development and characterization of monoclonal antibodies against canine PD-1 and PD-L1

Keywords: Dog; Monoclonal antibody; PD-1; PD-L1;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Transfer of gene-corrected T cells corrects humoral and cytotoxic defects in patients with X-linked lymphoproliferative disease

Keywords: X-linked lymphoproliferative disease; T-cell gene therapy; follicular helper T cells; T-cell cytotoxicity; BV; Brilliant Violet; CTL; Cytotoxic T lymphocyte; HLH; Hemophagocytic lymphohistiocytosis; HSCT; Hematopoietic stem cell transplantation; HVS; Herp

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

The unique biology and treatment of primary mediastinal B-cell lymphoma

Keywords: Anti-PD-1; CD30; Brentuximab vedotin; CHOP; DA-EPOCH; MACOP-B; PD-1; JAK/STAT; Primary mediastinal large B-Cell lymphoma; Pembrolizumab; Radiotherapy; Rituximab; Ruxolitinib; VACOP-B;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Dendritic cells conditioned by activin A-induced regulatory T cells exhibit enhanced tolerogenic properties and protect against experimental asthma

Keywords: Activin-A; allergic asthma; regulatory T cells; tolerogenic dendritic cells; immune regulation; Act-A-Treg; Activin-A-induced regulatory T; alum; Aluminum hydroxide; BAL; Bronchoalveolar lavage; BM-DCs; Bone marrow-derived dendritic cell; cDC; Convent

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

PD-1 /PD-L1 checkpoint in hematological malignancies

Keywords: PD-1; PD-L1; PD-1/PD-L1 checkpoint; Lymphoproliferative disorders; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Cooperativity of HOXA5 and STAT3 Is Critical for HDAC8 Inhibition-Mediated Transcriptional Activation of PD-L1 in Human Melanoma Cells

Keywords: HDAC; histone deacetylase; HOXA5; homeobox A5; PD-1; programmed death 1; PD-L1; programmed death-ligand 1; shRNA; short hairpin RNA; STAT3; signal transducer and activator of transcription 3;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Checkpoint inhibitors as treatment for malignant gliomas: “A long way to the top”

Keywords: Checkpoint inhibitors; Immunotherapy; Malignant gliomas; Glioblastoma; PD-1; PD-L1;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation

Keywords: BLI; bioluminescence imaging; BSA; bovine serum albumin; CTL; cytotoxic T lymphocytes; CRISPR/Cas; Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated nucleases; DEGs; differently expressed genes; DMEM; Dulbecco's modified Eagle's

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

DNA mismatch repair in cancer

Keywords: 5-FU; 5-fluorouracil; bMMRD; Biallelic mismatch repair deficiency; CD28; cluster of differentiation 28; CIN; Chromosomal instable; CR; complete response; CRC; colorectal cancer; CTL; cytotoxic T-lymphocytes; CTLA-4; cytotoxic T lymphocyte antigen-4; DFS;

دانلود رایگان متن کامل مقاله ISI 77 صفحه سال انتشار : 2018 سفارش ترجمه

TGFβ pathway inhibition in the treatment of non-small cell lung cancer

Keywords: ALK; Anaplastic leukemia kinase; CAF; Cancer-associated fibroblast; EGFR; Epidermal growth factor receptor; EMT; Epithelial-to-mesenchymal transition; MSC; Mesenchymal stem cell; NK Cell; Natural killer cell; NSCLC; Non-small cell lung cancer; OS; Overall

دانلود رایگان متن کامل مقاله ISI 82 صفحه سال انتشار : 2018 سفارش ترجمه

ORIGINAL ARTICLEFunction of PD-L1 in antitumor immunity of glioma cells

Keywords: Glioblastoma; PD-1; Pathogenesis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

A molecular and preclinical comparison of the PD-1-targeted T-cell checkpoint inhibitors nivolumab and pembrolizumab

Keywords: Nivolumab; Pembrolizumab; PD-1; T-cell checkpoint;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Enhanced expression of Programmed cell death 1 (PD-1) protein in benign vascular anomalies

Keywords: PD-1; PD-L1; haemangioma;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Hypoxia and HIF pathway in cancer and the placenta

Keywords: Oxygen; Hypoxia-inducible factor; Placenta; Trophoblast; Cancer; CCRCC; clear cell renal cell carcinoma; FasL; Fas ligand; FIH; factor inhibiting HIF; FLT1; fms-related tyrosine kinase 1; HIF; hypoxia-inducible factor; HLA; human leukocyte antigen; MHC; m

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Frequencies of PD-1- positive T CD3+CD4+, T CD3+CD8+ and B CD19+ lymphocytes in female patients with Graves' disease and healthy controls- preliminary study

Keywords: Graves' disease; PD-1; CD279; Hyperthyroidism; Lymphocytes;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

CD40 agonist converting CTL exhaustion via the activation of the mTORC1 pathway enhances PD-1 antagonist action in rescuing exhausted CTLs in chronic infection

Keywords: CD40 agonist; PD-1 antagonist; Chronic infection; CTL exhaustion; mTORC1 pathway; CTL; cytotoxic T lymphocytes; DT; diphtheria toxin; DC; dendritic cell; LCMV; lymphocytic choriomeningitis virus; OVA; ovalbumin; PD-1; programmed cell death protein 1; PD-L

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه