دانلود مقالات ISI درباره Pd-1 + ترجمه فارسی

Correlation between Classic Driver Oncogene Mutations in EGFR, ALK, or ROS1 and 22C3-PD-L1 ≥50% Expression in Lung Adenocarcinoma

Keywords: Lung cancer; PD-L1; PD-1; Pembrolizumab; EGFR; ALK;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Analysis of non-small cell lung cancer microenvironment indicates preponderance of T cell exhaustion marker expression

Keywords: CTLA4; cytotoxic T-lymphocyte-associated protein 4; LAG3; lymphocyte activated gene 3; PD-1; programmed cell death protein 1; CFSE; carboxyfluorescein succinimidyl ester; CD25 neg; CD25Dep cells; Lung cancer; Microenvironment; T cell; Exhaustion marker;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Management of Muscle-Invasive Urothelial Cancer and the Emerging Role of Immunotherapy in Advanced Urothelial Cancer

Keywords: AKT; AKT serine/threonine kinase 1; BCG; bacillus Calmette-Guérin; CTLA4; cytotoxic T-lymphocyte-associated protein 4; EGFR; epidermal growth factor receptor; FDA; Food and Drug Administration; FGFR; fibroblast growth factor receptor; GC; gemcitabine p

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome induced by nivolumab

Keywords: CT; computer tomography; PET; positron emission tomography; RS3PE; remitting seronegative symetrical synovitis with pitting edema; PD-1; programmed cell-death-1; PDL-1; programmed cell-death ligand-1; CRP; C-reactive protein; CCP; cyclic citrullinated pep

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Multicenter Comparison of 22C3 PharmDx (Agilent) and SP263 (Ventana) Assays to Test PD-L1 Expression for NSCLC Patients to Be Treated with Immune Checkpoint Inhibitors

Keywords: Non-small cell lung cancer; PD-1; PD-L1; Immunohistochemistry; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Progress in pathologyPD-L1 and immune escape: insights from melanoma and other lineage-unrelated malignancies

Keywords: PD-1; Programmed death receptor 1; PD-L1; Programmed death ligand 1; TIL; tumor-invading lymphocyte; TME; tumoral microenvironment; IFN; interferon; qRT-PCR; quantitative reverse-transcription polymerase chain reaction; NSCLC; non-small cell lung carcin

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Interleukin 10 enhanced CD8+ T cell activity and reduced CD8+ T cell apoptosis in patients with diffuse large B cell lymphoma

Keywords: Bcl-2; DLBCL; Interleukin 10; PD-1;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Chimeric antigen receptor T-cells for B-cell malignancies

Keywords: ALL; acute lymphoblastic leukemia; B-ALL; B-cell acute lymphoblastic leukemia; CAR-T; chimeric antigen receptor T-cell; CAR; chimeric antigen receptor; CD; cluster of differentiation; CHOP; Children's Hospital of Philadelphia; CLL; chronic lymphocytic leu

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Antibodies targeting BTLA or TIM-3 enhance HIV-1 specific T cell responses in combination with PD-1 blockade

Keywords: PD-1; BTLA; TIM-3; CD160; LAG-3; CTLA-4; Immune checkpoints; Coinhibitory receptors; T cell exhaustion; HIV-1; ADCC; antibody dependent cellular cytotoxicity; (c)ART; (combined) antiretroviral therapy; CDC; complement dependent cytotoxicity; CFSE; Carboxy

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

LAG-3 Protein Expression in Non-Small Cell Lung Cancer and Its Relationship with PD-1/PD-L1 and Tumor-Infiltrating Lymphocytes

Keywords: NSCLC; LAG-3; PD-1; PD-L1; Tumor-infiltrating lymphocytes;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade

Keywords: Cytokines; IL-17; Neutrophils; MDSC; PD-1; Resistance;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Atypical responses in patients with advanced melanoma, lung cancer, renal-cell carcinoma and other solid tumors treated with anti-PD-1 drugs: A systematic review

Keywords: Nivolumab; Pembrolizumab; PD-1; Anti-PD-1; Melanoma; Lung cancer;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Development of a robust reporter gene assay to measure the bioactivity of anti-PD-1/anti-PD-L1 therapeutic antibodies

Keywords: PD-1; PD-L1; Reporter gene assay; Monoclonal antibody; Bioactivity; Validation;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Development of novel avenues to overcome challenges facing CAR T cells

Keywords: AICD; activation-induced cell death; AMP; adenosine monophosphate; APC; antigen-presenting cells; ATP; adenosine triphosphate; CAFs; cancer-associated fibroblasts; CAR; chimeric antigen receptor; CEA; carcinoembryonic antigen; CTLA4; cytotoxic T-lymphocyt

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Prognostic Value of PD-1 and PD-L1 Expression in Patients with High Grade Upper Tract Urothelial Carcinoma

Keywords: urinary tract; carcinoma; biomarkers; lymphocytes; tumor-infiltrating; programmed cell death 1 receptor; CIS; carcinoma in situ; CSS; cancer specific survival; LVI; lymphovascular invasion; NRI; net reclassification improvement; OCD; organ confined diseas

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnancy favors the expansion of circulating functional follicular helper T Cells

Keywords: Bcl-6; transcription factor B cell lymphoma-6; CMV; cytomegalovirus; E2-17β; estradiol; ELISA; Enzyme-linked immunosorbent assay; GC; germinal center; HbsAg; hepatitis B superficial antigen; HBV; hepatitis B virus; HIV; Human immunodeficiency virus; IC

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Human regulatory B cells control the TFH cell response

Keywords: Regulatory B cells; follicular T helper cells; IL-12; IL-21; antibody production; humoral immune response; Bcl-6; B-cell lymphoma 6; Breg; Regulatory B; DC; Dendritic cell; Foxp3; Forkhead box P3; GC; Germinal center; ICAM; Intercellular adhesion molecule

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas

Keywords: Immunotherapy; GPC3; MAGEC2; Galectin 9; APC; antigen-presenting cells; BTLA; B and T lymphocyte attenuator; CFSE; carboxyfluorescein diacetate succinimidyl ester; CTL; cytotoxic T cells; CTLA4; cytotoxic T-lymphocyte associated protein 4; GAL-9; galecti

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Development of CAR T cells designed to improve antitumor efficacy and safety

Keywords: 28z; CD28 + CD3ζ; 4-1BBL; 4-1BB ligand; B-ALL; B cell acute lymphatic leukemia; BBz; 4-1BB + CD3ζ; CAR; chimeric antigen receptor; CD40L; CD40 ligand; CRS; cytokine release syndrome; CTLA-4; cytotoxic T-lymphocyte associated protein 4; DCs; dendriti

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver

Keywords: NK Cell; CXCL10; Mouse Model; IL10; HBe; cccDNA; covalently closed circular DNA; CHB; chronically HBV infected; ELISA; enzyme-Linked Immunosorbent Assay; ETV; entecavir; hAlb; human Albumin; HBcAg; hepatitis B core antigen; HBe; hepatitis B envelope; HBs;

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

Follicular helper T cells mediate IgE antibody response to airborne allergens

Keywords: Follicular T cells; IL-4; IgE; allergy; allergens; TH2 cells; APC; Antigen-presenting cell; BAL; Bronchoalveolar lavage; eGFP; Enhanced green fluorescent protein; FACS; Fluorescence-activated cell sorting; GC; Germinal center; HDM; House dust mite; ICOS;

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2017 سفارش ترجمه

Abscopal effect in a Hodgkin lymphoma patient treated by an anti-programmed death 1 antibody

Keywords: Abscopal effect; Irradiation; Out-of-field; Pembrolizumab; Hodgkin disease; PD-1;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Intracranial response to nivolumab in NSCLC patients with untreated or progressing CNS metastases

Keywords: CNS; central nervous system; K-RAS; Kirsten rat sarcoma; mRECIST; modified Response Evaluation Criteria in Solid Tumors; MRI; magnetic resonance imaging; NSCLC; non-small cell lung cancer; pts; patients; PET-CT; positron emission tomography-computer tomog

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

PD-1/PD-L1 expression in extra-medullary lesions of multiple myeloma

Keywords: Extramedullary myeloma; PD-L1; PD-1; Immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

The characteristic profiles of PD-1 and PD-L1 expressions and dynamic changes during treatment in active tuberculosis

Keywords: Tuberculosis; PD-1; PD-L1; T cell subsets;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

CD163+ M2-type tumor-associated macrophage support the suppression of tumor-infiltrating T cells in osteosarcoma

Keywords: Macrophage; TIM-3; PD-1; Osteosarcoma

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Short communicationHedgehog signaling regulates PDL-1 expression in cancer cells to induce anti-tumor activity by activated lymphocytes

Keywords: Hh; Hedgehog; MAML3; mastermind-like3; RBPJ; recombination signal binding protein for immunoglobulin-kappa-J region; PD-1; programmed death-1; PDL-1; programmed death ligand-1; Smo; Smoothened; PSK; protein-bound polysaccharide; NKG2D; natural-killer grou

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment

Keywords: PD-1; PD-L1; PD-L2; B7-H1; Immune checkpoint; Squamous cell carcinoma; Head and neck cancer; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Differential contribution of three immune checkpoint (VISTA, CTLA-4, PD-1) pathways to antitumor responses against squamous cell carcinoma

Keywords: CTLA-4; Head and neck squamous cell carcinoma; Immune checkpoint inhibitor; Immunotherapy; PD-1; Tumor microenvironment; VISTA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Treatment of murine lupus with PD-LIg

Keywords: PD-1; PD-L; Targeted therapy; Murine lupus;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Differential effects of inhibitors of the PI3K/mTOR pathway on the expansion and functionality of regulatory T cells

Keywords: iTregs; in vitro-induced Tregs; LAP; Latency Associated Peptide; PD-1; programmed death-1; pNET; pancreatic neuroendocrine tumor; PTEN; phosphatase and tensin homolog deleted on chromosome 10; pTregs; peripherally derived Tregs; Tconv; conventional T cell

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Programmed death (PD)-1 attenuates macrophage activation and brain inflammation via regulation of fibrinogen-like protein 2 (Fgl-2) after intracerebral hemorrhage in mice

Keywords: PD-1; Macrophage; Inflammation; Fgl-2; ICH;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

CD4+ and CD8+ T Cell Activation in Children with Hepatitis C

Keywords: BD; Becton, Dickinson and Company; EOMES; Eomesodermin; HCV; Hepatitis C virus; IFN; Interferon; IL; Interleukin; PBMC; Peripheral blood mononuclear cell; PD-1; Programmed cell death-1; SEB; Staphylococcal enterotoxin B; T-bet; T-box transcription factor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Predictive biomarkers of response to PD-1/PD-L1 immune checkpoint inhibitors in non-small cell lung cancer

Keywords: Immune checkpoint inhibition; PD-1; PD-L1; Biomarker; NSCLC;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Circulating T follicular helper cells are associated with rapid virological response in chronic hepatitis C patients undergoing peginterferon therapy

Keywords: T follicular helper cells; B cells; Cytokines; Hepatitis C virus; Interferon; PD-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

PD-L1 is upregulated by radiochemotherapy in rectal adenocarcinoma patients and associated with a favourable prognosis

Keywords: PD-L1; PD-1; Nivolumab; Pembrolizumab; Rectal; Cancer; Adenocarcinoma; Radiation; Radiochemotherapy; Radiotherapy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleCounter-regulation of rejection activity against human liver grafts by donor PD-L1 and recipient PD-1 interaction

Keywords: CFSE; carboxyfluorescein succinimidyl ester; CNI; calcineurin inhibitor; CTLA-4; cytotoxic T lymphocyte antigen 4; DC; dendritic cell; HWE; Hardy Weinberg Equilibrium; LT; liver transplantation; PBMC; peripheral blood mononuclear cells; PD-1; programmed d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

HESI/FDA workshop on immunomodulators and cancer risk assessment: Building blocks for a weight-of-evidence approach

Keywords: Immunotoxicology; Immunotoxicity; Immunomodulation; Immunosuppression; Carcinogenicity; Cancer; Risk assessment; CTL; cytotoxic T-lymphocytes; EBV; Epstein-Barr virus; FDA; Food and Drug Administration; HESI; Health and Environmental Sciences Institute;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewThe role of CTLA-4 and PD-1 in anti-tumor immune response and their potential efficacy against osteosarcoma

Keywords: CTLA-4; PD-1; Osteosarcoma; Checkpoint inhibitor; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibitory receptor expression on memory CD8 T cells following Ad vector immunization

Keywords: Adenovirus; Vector; PD-1; HIV-1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Rapid and objective CT scan prognostic scoring identifies metastatic patients with long-term clinical benefit on anti-PD-1/-L1 therapy

Keywords: CT scan; Prognostic score; Immunotherapy; PD-1; PD-L1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Immune biomarkers PD-1/PD-L1 and TLR3 in malignant pleural mesotheliomas

Keywords: Pleura; Mesothelioma; Immunohistochemistry; PD-L1; PD-1; TLR3; TILs;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

OX40 signaling in head and neck squamous cell carcinoma: Overcoming immunosuppression in the tumor microenvironment

Keywords: OX40; Oral cancer; Head and neck cancer; Immunotherapy; PD-1; CTLA-4

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Prevailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer

Keywords: Pancreatic cancer; T cells; Exhaustion; Immunotherapy; ACT; adoptive cell transfer; AP-1; activator protein-1; APC; antigen-presenting cells; CAR; chimeric antigen receptor; CTL; cytotoxic T cells; CTLA-4; cytotoxic T lymphocyte antigen 4; FDA; US Food an

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Correlation between PD-L1 expression and outcome of NSCLC patients treated with anti-PD-1/PD-L1 agents: A meta-analysis

Keywords: NSCLC; PD-1; PD-L1; Nivolumab; Pembrolizumab;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Insights into the development and regulation of T follicular helper cells

Keywords: Th; T helper; Tfh; T follicular helper; IL; interleukin; Ig; Immunoglobulin; STAT; signal transduction and activator of transcription; ICOS; inducible co-stimulator; SLAM; signaling lymphocytic activation molecule; SAP; slam associated protein; GC; germin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission

Keywords: hepatitis B virus; HBV e antigen; Kupffer cells; PD-1; PD-L1; HBV vertical transmission

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleEffector T cell function rather than survival determines extent and duration of hepatitis in mice

Keywords: Alb; albumin; B6; C57BL/6; CFSE; carboxyfluorescein succinimidyl ester; CTL; cytotoxic T lymphocyte; LN; lymph node(s); Met; metallothionein; PD-1; programmed cell death 1; PD-L1; programmed cell death-ligand 1; RAG; recombination-activating genes; SOCS-1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Successful Immunotherapy against a Transplantable Mouse Squamous Lung Carcinoma with Anti-PD-1 and Anti-CD137 Monoclonal Antibodies

Keywords: Immunotherapy; Lung cancer; Squamous; CD-137; PD-1; PD-L1;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Predictive Markers for the Efficacy of Anti-PD-1/PD-L1 Antibodies in Lung Cancer

Keywords: Lung cancer; Immunotherapy; PD-1; PD-L1; Biomarker;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه