Signaling pathway and dysregulation of PD1 and its ligands in lymphoid malignancies
Keywords: PD-1; PD-L1; PD-L2; Lymphoid malignancies; Pidilizumab; Nivolumab; Pembrolizumab
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Characterisation and management of dermatologic adverse events to agents targeting the PD-1 receptor
Keywords: Adverse events; Immune-checkpoint; Immunotherapy; Nivolumab; PD-1; Pembrolizumab; Programmed death-1; Pruritus; Rash; Vitiligo;
Review articlePD-1/PD-L and autoimmunity: A growing relationship
Keywords: PD-1; PD-L1; PD-L2; Autoimmunity;
Antitumor dendritic cell-based vaccines: lessons from 20Â years of clinical trials and future perspectives
Keywords: APCs; antigen-presenting cells; cDCs; classical DCs; CTLs; cytotoxic T cells; CTLA-4; cytotoxic T-lymphocyte-associated antigen 4; DC; dendritic cell; Dex; dendritic cell-derived exosomes; EMA; European Medicines Agency; FDA; Food and Drug Administratio
Diagnosis, monitoring and management of immune-related adverse drug reactions of anti-PD-1 antibody therapy
Keywords: Immunotherapy; PD-1; Nivolumab; Pembrolizumab; Adverse drug reaction; Immune-related adverse events;
Increased, but Functionally Impaired, CD14+ HLA-DR-/low Myeloid-Derived Suppressor Cells in Psoriasis: A Mechanism of Dysregulated T Cells
Keywords: iTreg; induced regulatory T cell; MDSC; myeloid-derived suppressor cell; Mo-MDSC; monocytic myeloid-derived suppressor cell; PBMC; peripheral blood mononuclear cell; PD-1; programmed cell death protein 1; PD-L1; programmed death-ligand 1; ROS; reactive ox
Myeloid-derived suppressor cells expressing a self-antigen ameliorate experimental autoimmune encephalomyelitis
Keywords: 7-AAD; 7-aminoactinomycin D; DMEM; Dulbecco's modified Eagle's medium; EGFP; enhanced green fluorescent protein; EAE; experimental autoimmune encephalomyelitis; EU; European Union; FBS; fetal bovine serum; GEE; generalized estimating equation; GFAP; glial
Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment
Keywords: APRIL; a proliferation-inducing ligand; ATM; ataxia telangiectasia mutated; BAFF; B-cell activating factor; BAFFR; BAFF receptor; BAG6; BCL2-associated athanogene 6; BCMA; B-cell maturation antigen; BCL2; B-cell lymphoma 2; BCR; B cell receptor; bFGF; bas
Rationale for combined blockade of PD-1 and CTLA-4 in advanced head and neck squamous cell cancer - Review of current data
Keywords: Nivolumab; Ipilimumab; Head and neck cancer; PD-1; CTLA-4; Immunotherapy;
Prognostic value of PD-1 and TIM-3 on CD3+ T cells from diffuse large B-cell lymphoma
Keywords: PD-1; TIM-3; Chemotherapy efficiency; Prognosis; Diffuse large B-cell lymphoma
Construction, expression, purification, and characterization of a dual-targeting PD-1/VEGF-A fusion protein (P-V)
Keywords: Anti-tumor; PD-1; VEGF-A; Dual targeting; Fusion protein; 293E cells;
Immunohistochemical status of PD-L1 in thymoma and thymic carcinoma
Keywords: Thymoma; Thymic carcinoma; PD-1; PD-L1; Immunohistochemistry; Clone E1L3N;
Efficacy of targeted therapies after PD-1/PD-L1 blockade in metastatic renal cell carcinoma
Keywords: Renal cell carcinoma; Targeted therapy; PD-1; PD-L1; VEGFR; mTOR
T cell metabolic fitness in antitumor immunity
Keywords: T cell metabolism; glycolysis; IDO; PD-1; CTLA4; tumor microenvironment; antitumor immunity; checkpoint blockade
PD-1 blockade therapy in renal cell carcinoma: Current studies and future promises
Keywords: PD-1; PDL-1; Renal cell carcinoma; Immunotherapy;
Feto-maternal immune regulation by TIM-3/galectin-9 pathway and PD-1 molecule in mice at day 14.5 of pregnancy
Keywords: TIM-3; Gal-9; PD-1; Pregnancy; Feto-maternal interface; ImmunityDC, dendritic cell; Gal-9, galectin-9; Gd, gestation day; PD-1, programmed cell death-1; RPMI 1640, Roswell Park Memorial Institute formulation 1640; QRT-PCR, quantitative real-time PCR; TIM-
Mechanisms of allergy and clinical immunologyHuman B cells promote T-cell plasticity to optimize antibody response by inducing coexpression of TH1/TFH signatures
Keywords: B cell; T-cell plasticity; IL-21; IFN-γ; coexpression; T-bet; Bcl-6; antibody response; crosstalk; Bcl-6; B cell lymphoma 6; DC; Dendritic cell; DP; Double positive; ICOS; Inducible costimulator; LN; Lymph node; PD-1; Programmed cell death 1; PE; Phycoer
Genetic variations of IL-28B and PD-1 are in association with the susceptibility and outcomes of HCV infection in Southeast China
Keywords: Chronic HCV infection; Spontaneous clearance; Polymorphism; IL-28B; PD-1;
Predictive biomarkers in PD-1/PD-L1 checkpoint blockade immunotherapy
Keywords: PD-L1; PD-1; Biomarkers; Immunotherapy; Response;
Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment
Keywords: Sarcoma; Immunotherapy; PD-1; PD-L1; Tumor infiltrating lymphocyte CD3+, CD4+, CD8+, FOXP3+
Polyclonal, newly derived T cells with low expression of inhibitory molecule PD-1 in tonsils define the phenotype of lymphocytes in children with Periodic Fever, Aphtous Stomatitis, Pharyngitis and Adenitis (PFAPA) syndrome
Keywords: PFAPA; Autoinflammatory disease; Flow cytometry; T lymphocyte; PD-1; TREC; KREC; T-cell receptor gene rearrangement; Tonsillectomy; Chemokine
Regulatory function of CD4+CD25++ T cells in patients with myasthenia gravis is associated with phenotypic changes and STAT5 signaling: 1,25-Dihydroxyvitamin D3 modulates the suppressor activity
Keywords: Treg; GITR; PD-1; STAT-5; Vitamin D; LOMG;
Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway
Keywords: PD-1; PD-L1; PD-L2; monoclonal antibody; human cancer; immunotherapy
Research ArticleA heterogeneous hierarchy of co-regulatory receptors regulates exhaustion of HCV-specific CD8 T cells in patients with chronic hepatitis C
Keywords: HCV; hepatitis C virus; PD-1; programmed death protein 1; CTLA-4; cytotoxic T lymphocyte-associated antigen 4; TIM-3; T cell immunoglobulin and mucin domain-containing protein 3; CMV; cytomegalovirus; EBV; Epstein-Barr virus; PBMC; peripheral blood mono
Expression of PD-1 and Its Ligands, PD-L1 and PD-L2, in Smokers and Never Smokers with KRAS-Mutant Lung Cancer
Keywords: PD-1; PD-L1; PD-L2; KRAS mutation; Lung cancer; Cancer immunotherapy
Upregulation of PD-1 on CD4+CD25+T cells is associated with immunosuppression in liver of mice infected with Echinococcus multilocularis
Keywords: PD-1; PD-L1; Tregs; Echinococcus multilocularis; Infection
PD-1 and PD-L1 blockade in gastrointestinal malignancies
Keywords: Programmed death; PD-1; PD-L1; Gastrointestinal cancer; Immunotherapy; Immune checkpoint blockade;
Overcoming T cell exhaustion in infection and cancer
Keywords: PD-1; PD-L1; T cell exhaustion; immunotherapy; cancer; chronic infection
A Systematic Review of Immunotherapy in Urologic Cancer: Evolving Roles for Targeting of CTLA-4, PD-1/PD-L1, and HLA-G
Keywords: Cancer immunotherapy; Monoclonal antibodies; Checkpoint; CTLA-4; PD-1; HLA-G;
Tumor-infiltrating lymphocytes, forkhead box P3, programmed death ligand-1, and cytotoxic T lymphocyte-associated antigen-4 expressions before and after neoadjuvant chemoradiation in rectal cancer
Keywords: CD8; cluster of differentiation 8; NK; natural killer cell; MDSCs; myeloid-derived suppressor cells; TILs; tumor-infiltrating lymphocytes; FOXP3; transcription factor forkhead box P3; PD-L1; programmed death ligand-1; CTLA-4; cytotoxic T lymphocyte-associ
Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation
Keywords: PD-L1; PD-1; EGFR; Tyrosine kinase inhibitors; NSCLC;
Current state of anti-PD-L1 and anti-PD-1 agents in cancer therapy
Keywords: PD-L1; PD-1; Immunotherapy; Immune evasion; Cancer;
Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies
Keywords: Follicular helper T cells; humoral immunity; primary immunodeficiencies; cytokine signaling; Bcl-6; B-cell lymphoma 6; cTFH; Circulating follicular helper T; DN; Double-negative; DP; Double-positive; GC; Germinal center; GOF; Gain of function; IL-10R; IL-
Skin dendritic cells induce follicular helper T cells and protective humoral immune responses
Keywords: Steady-state conditions; skin dendritic cells; T follicular helper cells; protective humoral immune responses; CFA; Complete Freund adjuvant; CFSE; Carboxyfluorescein succinimidyl ester; DC; Dendritic cell; EAE; Experimental autoimmune encephalomyelitis;
Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells
Keywords: Chronic Infection; Hepatitis; Tolerance; ALT; alanine aminotransferase; APC; allophycocyanin; Arm; Armstrong strain; BTLA; B and T lymphocyte attenuator; CFSE; carboxyfluorescein diacetate succinimidyl ester; CTL; cytotoxic T lymphocyte; ELISA; enzyme-lin
The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma
Keywords: melanoma; MPDL3280A; nivolumab; PD-1; PD-L1; pembrolizumab; pidilizumab; programmed cell death 1;
The role of the PD-L1:PD-1 pathway in squamous cell carcinoma of the head and neck
Keywords: PD-L1; B7-H1; PD-1; Squamous; Head and neck; Immunotherapy;
Soluble production of a biologically active single-chain antibody against murine PD-L1 in Escherichia coli
Keywords: PD-L1; PD-1; Antibody; Avian library; Phage display; scFv; Affinity;
Research ArticleRestoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation
Keywords: HBV; hepatitis B virus; HBeAg; hepatitis B e antigen; HIV; human immunodeficiency virus; PD-1; programmed cell death protein 1; CTLA-4; cytotoxic T-lymphocyte protein 4; 2B4; natural killer cell receptor 2B4; BTLA; B and T lymphocyte attenuator; Tim-3; T
Changes in immune cell populations in the periphery and liver of GBV-B-infected and convalescent tamarins (Saguinus labiatus)
Keywords: HCV; hepatitis C virus; GBV-B; GB virus B; PD-1; programmed death receptor-1; PD1-L1; programmed death receptor-1 ligand; CTLA4; cytotoxic T lymphocyte antigen-4; NS; non-structural; vRNA; viral ribonucleic acid; qRT-PCR; quantitative reverse transcriptas
Viral infections in asthma and COPD
Keywords: RSV; respiratory syncytial virus; HRV; human rhinovirus; LAI; lower airway infection; AHR; airway hyperresponsiveness; TLR3; Toll-like receptor 3; RIG-I; retinoic acid-inducible gene I; MDA5; melanoma differentiation-associated gene 5; TRIF; Toll/IL-1R do
Programmed death-1 receptor suppresses γ-IFN producing NKT cells in human tuberculosis
Keywords: Programmed death-1; Natural killer T cell; T helper-1; Effector T cells; Inteferon-gamma; APCs; antigen presenting cells; ATD; anti-tubercular drugs; Ag; antigen; Cat-I; category-I; Cat-II; category-II; HCs; healthy controls; IFN-γ; interferon gamma; IL-
Xenogeneic therapeutic cancer vaccines as breakers of immune tolerance for clinical application: To use or not to use?
Keywords: BCG; Bacillus Calmette-Guérin; BMDC; bone marrow-derived dendritic cell; CTA; cancer/testis antigen; CTL; cytotoxic T lymphocyte; CTLA-4; cytotoxic T lymphocyte antigen-4; DC; dendritic cell; DNA; deoxyribonucleic acid; DTH; delayed-type hypersensitivity
Immunological in vivo effects of B7-H1 deficiency
Keywords: Immunomodulation; Immunosuppressive molecules; B7-H1; B7-H1 deficiency; B7-H1 knockout mice; B7-H1; B7-homolog 1, CD274; DC; dendritic cell; KO; knockout; PD-1; programmed cell death protein 1, CD279; Tcm; T central memory; Tcon; T conventional cell; Tem;
Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome)
Keywords: biologic and molecular markers; clinical and diagnostic challenges; cutaneous T-cell lymphoma; genetic aberrations; histopathology; mycosis fungoides; mycosis fungoides subtypes; pathogenesis; prognostic value; Sézary syndrome; skin homing features; tran
Tolerogenic signaling by pulmonary CD1c+ dendritic cells induces regulatory T cells in patients with chronic obstructive pulmonary disease by IL-27/IL-10/inducible costimulator ligand
Keywords: Chronic obstructive pulmonary disease; dendritic cells; regulatory T cells; IL-27; IL-10; inducible costimulator ligand; AHR; Aryl hydrocarbon receptor; APC; Antigen-presenting cell; BAL; Bronchoalveolar lavage; CD1c+DCCOPD; CD1c+ DCs from lung samples ob
Targeting the PD1/PD-L1 axis in melanoma: Biological rationale, clinical challenges and opportunities
Keywords: PD-1; PD-L1; Melanoma;
Research ArticleInhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells
Keywords: DC; dendritic cell; LSEC; liver sinusoidal endothelial cell; MFI; mean fluorescence intensity; MHC; major histocompatibility complex; Th cell; T helper cell; IL; interleukin; PD-1; programmed death-1; IFN-γ; interferon-γ; CD4 T cells; Inflammation; Immu
Changes in the balance between Treg and Th17 cells in patients with chronic hepatitis B
Keywords: CHB; Chronic hepatitis B; HBV; Hepatitis B virus; PD-1; Procedural death factor-1; Treg; T; Th17; T helper 17; NK; Natural killer; DC; Dendritic cells; IL-17; Interleukin-17; TGF-β1; Transforming growth factor-β1; CHB-LM; Low to moderate chronic hepatit
Tim-3 alters the balance of IL-12/IL-23 and drives TH17 cells: Role in hepatitis B vaccine failure during hepatitis C infection
Keywords: ALT; alanine transaminase; AST; aspartate transaminase; HBV; hepatitis B virus; HBV-NR; hepatitis B vaccine non-responder; HBV-R; hepatitis B vaccine responder; HCV; hepatitis C virus; HIV; human immunodeficiency virus; HS; healthy subject; IL-12; interle