Keywords: Bladder; Cancer; PDK4; Metabolism; Glycolysis; Mitochondria;
مقالات ISI (ترجمه نشده)
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Keywords: PDK4; NASH; Hepatic steatosis;
Keywords: ROS; reactive oxygen species; Prx; peroxiredoxin; PTP1B; protein tyrosine phosphatase 1B; PTEN; phosphatase and tensin homologue; MEFs; mouse embryonic fibroblasts; Nac; N-acetyl cysteine; GTT; glucose tolerance test; GLUT4; glucose transporter type 4; PT
Keywords: Circadian clock; Human; Serum metabolome; Skeletal muscle metabolome; High fat diet; High carbohydrate diet; 18S rRNA; 18S ribosomal RNA; ANOVA; analysis of variance; BHBA; β-hydroxybutyric acid; BMI; body mass index; Bmal1; brain and muscle ARNT-Like 1;
Keywords: 18S; 18S ribosomal RNA; 36B4; acidic ribosomal protein 36B4; Acc1; acetyl-CoA carboxylase α; Acox1; acyl-CoA oxidase 1; Apob; apolipoprotein B; ARE; antioxidant response element; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ATF4; activ
Keywords: AF-1; activation function-1; AF-2; activation function-2; AP-1; activator protein 1; dppp; 1,3-bis(diphenylphosphino)propane; DEX; dexamethasone; DIEA; N,N-diisopropylethylamine; FKBP5; FK506-binding protein 5; GR; glucocorticoid receptor; GRE; glucocorti
Keywords: B2M; beta-2-microglobulin; BMI; body mass index; CCL; chemokine (C-C motif) ligand; cDNA; complimentary deoxyribonucleic acid; CXCL16; chemokine (C-X-C motif) ligand 16; DPP4; dipeptidyl-peptidase 4; DXA; dual energy X-ray absorptiometry; g; gravity; Gadd
Keywords: High-risk Western-type diet; Intestinal cancer; Energy metabolism; Loss of heterozygosity; PDK4; ERK; ApcMin/+ mice;
Keywords: Ad; adenovirus; ADP; adenosine diphosphate; ATP; adenosine triphosphate; ATP-5β; ATP synthase 5β; BNP; brain natriuretic peptide; β-MHC; β-myosin heavy chain; CPT; carnitine palmitoyltransferase; Cyt b; cytochrome b; ERR; estrogen-related receptor; FA
Keywords: ACADM; medium chain acyl-CoA dehydrogenase; ACADVL; very long chain acyl-CoA dehydrogenase; ACC; acetyl-coenzyme A carboxylase alpha; ACSL1; acyl-CoA synthetase long-chain family member 1; ADIPOR2; adiponectin receptor 2; Akt; protein kinase B; AK2; Adeny
Keywords: ACADl; acyl-CoA dehydrogenase, long chain; ACADm; acyl-CoA dehydrogenase, medium chain; ACADvl; acyl-CoA dehydrogenase, very long chain; AMPK; 5â² AMP-activated protein kinase; CD36; cluster of differentiation 36; CPT2; carnitine palmitoyltransferase II;
Keywords: AICAR; 5â²aminoimidazole-4-carboxyamide-ribonucleoside; AD; Alzheimer's disease; ATF-2; activating transcription factor-2; AMPK; AMP-activated protein kinase; Bnip3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BnipL/Nix; BCL2/adenovirus E1B 19Â
Keywords: FOXO; forkhead box O; GC; glucocorticoids; MuRF-1; muscle RING-finger protein-1; mTOR; mammalian target of rapamycin; IGF-I; Insulin-like Growth Factor-I; eIF4E; eukaryotic translation initiation factor 4E; S6K1; ribosomal protein kinase 1; 4E-BP1; eukary
Adropin regulates pyruvate dehydrogenase in cardiac cells via a novel GPCR-MAPK-PDK4 signaling pathway
Keywords: Adropin; Mitochondria; PDK4; GRP19; GPCR; Pyruvate dehydrogenase; Metabolism;
The miR-15b-5p/PDK4 axis regulates osteosarcoma proliferation through modulation of the Warburg effect
Keywords: miR-15b-5p; Osteosarcoma; PDK4; Proliferation; Warburg effect;
Metabolic reprogramming in colon cancer reversed by DHTS through regulating PTEN/AKT/HIF1α mediated signal pathway
Keywords: DHTS; dihydrotanshinone I; LCFAs; long-chain fatty acids; PTEN; phosphatase and tensin homolog gene; HIF1α; hypoxia inducible factor 1 alpha; HKII; hexokinase II; p-AKT; phosphorylated protein kinase B; RHEB; Ras homolog enriched in brain; SIRT3; Silent
Adipocytes spectrum - From homeostasia to obesity and its associated pathology
Keywords: Acrp30 (AdipoQ); adiponectin gene; AdipoR; adiponectin receptor; AGE; angiotensinogen; ALP; alkaline phosphatase; Ang II; angiotensin II; Angptl2; angiopoietin-like protein-2; Aqp7; aquaporin-7; aP2; adipocyte-specific fatty acid binding protein 2 gene; A
Peroxisome Proliferator Activated Receptor Beta (PPARβ) activity increases the immune response and shortens the early phases of skeletal muscle regeneration
Keywords: Inflammation; Muscle injury; Macrophage; Reparation; Peroxisome proliferator activated receptor; Pax; paired-box; Myf; myogenic factor; MyoD; myogenic differentiation; MRF; myogenic regulatory factor; PPAR; peroxisome proliferator activated receptor; Treg
CK2 inhibition induced PDK4-AMPK axis regulates metabolic adaptation and survival responses in glioma
Keywords: CK2; PDK4; AMPK; CREB; Glioblastoma
Pyruvate stimulates mitophagy via PINK1 stabilization
Keywords: PDK4; Pyruvate; Mitophagy; PARK2; PINK1; LC3;
Myocardial energy provision is preserved by increased utilization of glucose and ketone bodies in CD36 knockout mice
Keywords: LCFA; long-chain fatty acid; BMIPP; 15-(p-iodophenyl)-(R, S)-methyl pentadecanoic acid; FDG; fluorodeoxy-glucose; PET; positron emission tomography; GLUT; glucose transporter; FOV; field-of-view; SUV; standardized uptake value; 3D-ROI; three-dimensional r
Comparative transcriptomic analysis by RNA-seq to discern differential expression of genes in liver and muscle tissues of adult Berkshire and Jeju Native Pig
Keywords: DEGs; differentially expressed genes; JNP; Jeju Native Pig; GO; gene ontology; NGS; next generation sequencing; PE; paired-ends; CASAVA-v1.7; Consensus Assessment of Sequence and Variation v 1.7; UCSC; University of California Santa Cruz; EASE; Expression
Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity
Keywords: α-SA; alpha skeletal actin; Atg3; autophagocytosis associated protein 3; β-MHC; beta myosin heavy chain; CPT-1; carnitine palmitoyl transferase 1; FAO; fatty acid oxidation; GLUT1; glucose transporter 1; GLUT4; glucose transporter 4; HDL; high density l
MDG-1, a polysaccharide from Ophiopogon japonicus, prevents high fat diet-induced obesity and increases energy expenditure in mice
Keywords: Ophiopogon japonicus; Polysaccharide; Anti-obesity; Energy expenditure; Diet induced obesity; Mitochondrial function; T2DM; type 2 diabetes mellitus; HFD; high fat diet; qPCR; quantitative real-time polymerase chain reaction; RER; respiratory exchange rat
Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders
Keywords: AGRP; agouti-related protein; AMPK; AMP-activated protein kinase; AP-1; activator protein-1; BCL10; B-cell lymphoma/leukemia-10; CIITA; class II, major histocompatibility complex, transactivator; DHA; docosahexaenoic acid; E2F1; transcription factor E2F1;
Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: A key to lean phenotype
Keywords: ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; aP2-Ucp1 mice; transgenic mice expressing UCP1 gene from the aP2 gene promoter; AA; arachidonic acid; ATM; adipose tissue macrophages; BAT; brown adipose tissue; BCAA; branched-chain amino a
Early induction of a brown-like phenotype by rosiglitazone in the epicardial adipose tissue of fatty Zucker rats
Keywords: Rosiglitazone; Epicardial adipose tissue; Fatty rat; TZD; thiazolidinedione; RSG; rosiglitazone; TG; triglycerides; PPARγ; peroxisome proliferator-activated receptor gamma; RXR; retinoid X receptor; CEBP; CCAAT enhancer binding protein; RAT; retroperiton
TNF-α inhibits PPARβ/δ activity and SIRT1 expression through NF-κB in human adipocytes
Keywords: CPT-1b; carnitine palmitoyl transferase 1; HDL; high-density lipoprotein; IL-6; interleukin-6; MCP-1; monocyte chemoattractant protein-1; NF-κB; nuclear factor-κB; PDK4; pyruvate dehydrogenase kinase 4; PGC-1α; PPARγ co-activator 1α; PPAR; peroxisome
The regulation of cancer cell death and metabolism by extracellular matrix attachment
Keywords: ECM; extra cellular matrix; ROS; reactive oxygen species; PPP; pentose phosphate pathway; TCA; tricarboxylic acid; PDH; pyruvate dehydrogenase; PDK4; pyruvate dehydrogenase kinase 4; ANGPTL4; angiopoietin-like 4; PK; pyruvate kinase; TIGAR; TP53-induced g
Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase
Keywords: ASMs; acid soluble metabolites; ACSL; long-chain fatty acyl-CoA synthetase; ATGL; adipose triglyceride lipase; BSA; bovine serum albumin; CA; cell-associated; CD36/FAT; fatty acid translocase; FDR; false discovery rate; CE; cholesteryl ester; CRAT; carnit
Activation of peroxisome proliferator-activated receptor-β/-δ (PPARβ/δ) prevents endothelial dysfunction in type 1 diabetic rats
Keywords: ACh; acetylcholine; CPT-1; carnitine palmitoyltransferase 1; DAPI; 4,6-diamidino-2-phenylindole dichlorohydrate; DHE; dihydroethidium; eNOS; endothelial NO synthase; EDHF; endothelium-derived hyperpolarizing factor; HR; heart rate; MCP-1; monocyte chemoat
Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis
Keywords: FXR; farnesoid X receptor; SHP; small heterodimer partner; BSEP; bile salt export pump; MCD; methionine- and choline-deficient; NASH; nonalcholic steatohepatitis; NAFLD; non-alcoholic fatty liver disease; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; stero
Circadian expression of FGF21 is induced by PPARα activation in the mouse liver
Keywords: Circadian rhythm; FGF21; Fibrate; PDK4; Fasting; PPARα
Discovery of a novel class of PPARδ partial agonists
Keywords: PPARd; Partial agonist; CPT1a; PDK4
Cloning and expression of PDK4, FOXO1A and DYRK1A from the hibernating greater horseshoe bat (Rhinolophus ferrumequinum)
Keywords: PDK4; FOXO1A; DYRK1A; Northern blot; Hibernate; Rhinolophus ferrumequinum
Leptin stimulation of COXIV is impaired in obese skeletal muscle myotubes
Keywords: mRNA; Fat metabolism; Obesity; COXIV; PDK4
Regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor
Keywords: PDK4; Glucocorticoids; PPAR; TRB-3; FOXO; Bile acids; Diabetes; Lipid; Glucose;