Keywords: انسداد شریان مغزی میانی دائمی; AChA; anterior choroidal artery; AChAO; anterior choroidal artery occlusion; ET-1; endothelin-1; MCA; middle cerebral artery; MCAO; middle cerebral artery occlusion; pMCAO; permanent middle cerebral artery occlusion; tMCAO; transient middle cerebral arter
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Keywords: انسداد شریان مغزی میانی دائمی; Apoptosis; Gliosis; Hypothermia; Partial reperfusion injury; Permanent middle cerebral artery occlusion; Transarterial regional hypothermia;
Keywords: انسداد شریان مغزی میانی دائمی; AD; Alzheimer's disease; Aβ; amyloid-β; BBB; blood-brain barrier; BCAO; bilateral carotid artery occlusion; Cbx; carbenoxolone; CM; conditioned media; Cx43; connexin43; Cxs; connexins; ECM; extracellular matrix; FGF1; fibroblast growth factor; GFAP;
Keywords: انسداد شریان مغزی میانی دائمی; CNS; central nervous system; MRI; magnetic resonance imaging; PET; positron emission tomography; pMCAO; permanent middle cerebral artery occlusion; USPIO; ultra small supraparamagnetic iron oxide particles; VOI; volumes of interest; chronic post-stroke ph
Keywords: انسداد شریان مغزی میانی دائمی; ACA; anterior cerebral artery; ADR; alpha-to-delta ratio; AP; anterior-posterior; AVA; Agri-Food and Veterinary Authority of Singapore; BBB; blood-brain barrier; CBF; cerebral blood flow; CBV; cerebral blood volume; cM1; contralateral motor cortical r
Keywords: انسداد شریان مغزی میانی دائمی; I/R; ischemia/reperfusion; p-MCAO; permanent middle cerebral artery occlusion; t-MCAO; transient middle cerebral artery occlusion; Ischemic stroke; Liposome; Ischemic penumbra; Middle cerebral artery occlusion; Laser Doppler perfusion imaging;
Keywords: انسداد شریان مغزی میانی دائمی; 7-AAD; 7-aminoactinomycin D; BSA; bovine serum albumin; COMP; cartilage oligomeric matrix protein; CFSE; carboxyfluorescein succinimidyl ester; DAPI; 4â²6-diamidino-2-phenylindole; DCX; doublecortin; DTOPV; diphenylamino-s-triazine-bridged p-phenylene vi
Keywords: انسداد شریان مغزی میانی دائمی; Ischemic stroke; Gait analysis; Permanent middle cerebral artery occlusion; Rat;
RIP1K Contributes to Neuronal and Astrocytic Cell Death in Ischemic Stroke via Activating Autophagic-lysosomal Pathway
Keywords: انسداد شریان مغزی میانی دائمی; 3-MA; 3-methyladenine; AO; Acridine Orange; DMEM; Dulbecco's Modified Eagle's Medium; GFAP; glial fibrillary acidic protein; HRP; horseradish peroxidase; LC3 II; light chain 3 II; LDH; lactate dehydrogenase; LMP; lysosomal membrane permeability; MAP2; mic
Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage
Keywords: انسداد شریان مغزی میانی دائمی; ADC; apparent diffusion coefficient; ATf; apotransferrin; B-27; a medium supplement to grow neurons; BBB; blood-brain barrier; CM; conditioned medium; CM-H2DCFDA; 5-chloromethyl-2,7-dichlorodihydrofluorescein diacetate; DAPK-1; anti-death-associated prote
Anti-inflammatory activity and chemical composition of dichloromethane extract from Piper nigrum and P. longum on permanent focal cerebral ischemia injury in rats
Keywords: انسداد شریان مغزی میانی دائمی; Anti-inflammatory; HPLC; Permanent middle cerebral artery occlusion; Piperine;
Post-stroke treatment with 17β-estradiol exerts neuroprotective effects in both normotensive and hypertensive rats
Keywords: انسداد شریان مغزی میانی دائمی; E2; 17β-estradiol; Et-1; endothelin-1; GFAP; glial fibrillary acidic protein; MAP; mean arterial blood pressure; NDS; neurological deficit score; pMCAO; permanent middle cerebral artery occlusion; SHR; spontaneously hypertensive rats; tMCAO; transient mi
Beneficial potential of intravenously administered IL-6 in improving outcome after murine experimental stroke
Keywords: انسداد شریان مغزی میانی دائمی; Inflammation; Cytokines; Chemokines; Interleukin-6 receptor; gp130; IL-10; CXCL1; Neutrophils; Focal cerebral ischemia; Permanent middle cerebral artery occlusion;
Infiltration of invariant natural killer T cells occur and accelerate brain infarction in permanent ischemic stroke in mice
Keywords: انسداد شریان مغزی میانی دائمی; iNKT cells; Inflammatory cytokines; Permanent middle cerebral artery occlusion; Ischemic stroke;
Induced cortical neurogenesis after focal cerebral ischemia - Three active components from Huang-Lian-Jie-Du Decoction
Keywords: انسداد شریان مغزی میانی دائمی; HLJDD; Huang-Lian-Jie-Du-Decoction; BrdU; 5-bromodeoxyuridine; TCM; Traditional Chinese Medicine; pMACO; permanent middle cerebral artery occlusion; CNS; Central Nervous System; VEGF; Vascular Endothelial Growth Factor; Ang; Angiopoietin; qRT-PCR; quantit
β-Dystroglycan cleavage by matrix metalloproteinase-2/-9 disturbs aquaporin-4 polarization and influences brain edema in acute cerebral ischemia
Keywords: انسداد شریان مغزی میانی دائمی; Ang II; Angiotensin II; ANOVA; analysis of variance; AQP4; aquaporin-4; BBB; blood-brain barrier; BM; basement membrane; BP; blood pressure; DG; dystroglycan; DGC; dystrophin glycoprotein complex; HE; hematoxylin-eosin; ICA; internal carotid artery; M
Two-color Dye-swap DNA Microarray approach toward confident gene expression profiling in PMCAO mouse model for ischemia-related and PACAP38-influenced genes
Keywords: انسداد شریان مغزی میانی دائمی; Permanent middle cerebral artery occlusion; Brain ischemia; Infract core; Penumbra; Neuropeptide
The high-mobility group I-Y transcription factor is involved in cerebral ischemia and modulates the expression of angiogenic proteins
Keywords: انسداد شریان مغزی میانی دائمی; ANGPT-1; angiopoietin 1; CCA; common carotid arteries; ChIP; chromatin immunoprecipitation; DAPI; 4â²,6-diamidino-2-phenylindole; GFAP; glial fibrillary acidic protein; HMGIY/HMGA1; high-mobility group I-Y protein; MTT; 3-(4,5-dimethylthiazol)-2,5-diphen
The immunomodulatory effect of bone marrow stromal cells (BMSCs) on interleukin (IL)-23/IL-17-mediated ischemic stroke in mice
Keywords: انسداد شریان مغزی میانی دائمی; BMSC; Bone marrow stromal cell; IL; Interleukin; pMCAO; Permanent middle cerebral artery occlusion; PBS; Phosphate-buffered saline; RT-PCR; Reverse transcriptase-polymerase chain reaction; ELISA; Enzyme-linked immunosorbent assay; t-PA; Tissue-plasminogen
Iron overload, measured as serum ferritin, increases brain damage induced by focal ischemia and early reperfusion
Keywords: انسداد شریان مغزی میانی دائمی; IST; in situ thromboembolic model; mNSS; modified neurologic score severity; pMCAO; permanent middle cerebral artery occlusion; ROS; reactive oxygen species; Blood-brain barrier; Edema; Haemorrhagic transformation; Mice; Thrombin;
Prostaglandin FP receptor inhibitor reduces ischemic brain damage and neurotoxicity
Keywords: انسداد شریان مغزی میانی دائمی; Ca2+; calcium; COX; cyclooxygenase; FP receptor; PGF2α receptor; FPâ/â; FP receptor knockout; pMCAO; permanent middle cerebral artery occlusion; OGD; oxygen-glucose deprivation; WT; wildtype; HBSS; Hanks' buffered saline solution; LDH; lactate dehydr
Research reportPolydatin modulates inflammation by decreasing NF-κB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood-brain barrier permeability for its neuroprotective effect in pMCAO rat brain
Keywords: انسداد شریان مغزی میانی دائمی; Permanent middle cerebral artery occlusion; Neuroprotection; Polydatin; Glioma-associated oncogene homolog1; Superoxide dismutase 1; Nuclear factor-kappa B;
Neuroprotective effect of cyanidin-3-O-glucoside anthocyanin in mice with focal cerebral ischemia
Keywords: انسداد شریان مغزی میانی دائمی; Permanent middle cerebral artery occlusion; Cyanidin-3-O-glucoside; Neuroprotective; Cytochrome c; Apoptosis-inducing factor
Research ReportErythropoietin prevents nitric oxide and cathepsin-mediated neuronal death in focal brain ischemia
Keywords: انسداد شریان مغزی میانی دائمی; Apoptosis; Brain; Cathepsin; Erythropoietin; Nitric oxide; Permanent middle cerebral artery occlusion; TUNEL staining;
Progesterone and allopregnanolone attenuate blood–brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases
Keywords: انسداد شریان مغزی میانی دائمی; Permanent middle cerebral artery occlusion; Progesterone; Allopregnanolone; Blood–brain barrier; Cytokines; Inflammatory response; Ischemia; Metalloproteinases; Tight junction proteins; Tumor necrosis factor-alpha
Heme oxygenase 1 is associated with ischemic preconditioning-induced protection against brain ischemia
Keywords: انسداد شریان مغزی میانی دائمی; IPC; ischemic preconditioning; MCA; middle cerebral artery; tMCAO; transient middle cerebral artery occlusion; pMCAO; permanent distal middle cerebral artery occlusion; HO1; heme oxygenase 1; TIA; transient ischemic attack; WT; wildtype; HO1â/â mice;
Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia
Keywords: انسداد شریان مغزی میانی دائمی; cerebral ischemia; middle cerebral artery occlusion; mouse; prostaglandins; PGD2; CBF; cerebral blood flow; COX; cyclooxygenase; H-PGDS; hematopoietic prostaglandin D synthase; L-PGDS; lipocalin-type prostaglandin D synthases; MABP; mean arterial blood pr
Protective effect of Ginkgolids (A + B) is associated with inhibition of NIK/IKK/IκB/NF-κB signaling pathway in a rat model of permanent focal cerebral ischemia
Keywords: انسداد شریان مغزی میانی دائمی; GKAB; Ginkgolid A and B, Ginkgolids (A + B); IKK; IκBα kinase; NIK; NF-κB-inducing kinase; NF-κB; nuclear factor kappaB; LPS; lipopolysaccharide; pMCAO; permanent middle cerebral artery occlusion; p-NIK,; phosphorylated NIK; p-IKKα,; phosphorylated
Cellular neuroscienceInvolvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice
Keywords: انسداد شریان مغزی میانی دائمی; ER-stress; mouse; permanent middle cerebral artery occlusion; stroke; ATF-4; activating transcription factor-4; BiP; immunoglobulin binding protein; CHOP; C/EBP-homologous protein; DAB; diamino benzidine; eIF2α; eukaryotic initiation factor 2α; ER; endo
Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice
Keywords: انسداد شریان مغزی میانی دائمی; focal cerebral ischemia; cytokines; receptors; signaling; microglia-macrophages; AP; alkaline phosphatase; BM; bone marrow; DAB; diaminobenzidine; FCS; fetal calf serum; GFP; green fluorescent protein; HPRT1; hypoxanthine phosphoribosyltransferase 1; HRP;
Activation of NF-kB and ERK1/2 after permanent focal ischemia is abolished by simvastatin treatment
Keywords: انسداد شریان مغزی میانی دائمی; Statin; Inflammation; Cerebral ischemia; Permanent middle cerebral artery occlusion; Transcription factor; MAP kinase; Rat
Enhancement of neuroprotection and heat shock protein induction by combined prostaglandin A1 and lithium in rodent models of focal ischemia
Keywords: انسداد شریان مغزی میانی دائمی; PGA1; prostaglandin A1; pMCAO; permanent middle cerebral artery occlusion; HSP; heat shock protein; GRP; glucose-regulated protein; CHOP; C/EBP homologous protein; GADD; growth arrest and DNA damage-inducible gene; CCA; common carotid artery; ECA; externa
Validation of two reference genes for mRNA level studies of murine disease models in neurobiology
Keywords: انسداد شریان مغزی میانی دائمی; Reference gene; Gene expression; Real-time PCR; PCR efficiency; Permanent middle cerebral artery occlusion; Perforant path lesion
Nitrone derivatives of trolox as neuroprotective agents
Keywords: انسداد شریان مغزی میانی دائمی; Neuroprotection; Free radical scavenging; Lipid peroxidation; Permanent middle cerebral artery occlusion; Nitrone; Trolox