Keywords: NIC; nicotine; JAK2; janus tyrosine kinase; STAT3; signal transducer and activator of transcription 3; SOCS3; suppressor of cytokine signaling 3; OB-R; leptin receptors; GD; gestational day; isSWAT; interscapular subcutaneous white adipose tissue; igSWAT;
مقالات ISI (ترجمه نشده)
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Keywords: NAFLD; non-alcoholic fatty liver disease; NAFL; non-alcoholic fatty liver; NASH; non-alcoholic steatohepatitis; mtDNA; mitochondrial DNA; FFAs; free fatty acids; TNF; tumor necrosis factor; CTRL; control; HF; high-fat; HF+HCh; high-fat+high-cholesterol; 7
Keywords: GDM; gestational diabetes mellitus; T2D; type 2 diabetes; CVD; cardiovascular disease; DOHaD; developmental origins of health and disease; CDA; Canadian diabetes association; HOMA-IR; homeostatic model assessment for insulin resistance; DINT; dietary inte
Keywords: ACS; Acyl-CoA synthetase; ARE/EpRE; Antioxidant/electrophile response element; Bcl-2; B-cell lymphoma 2; BMI; Body mass index; BSP; Broccoli sprout powder; CAT; Catalase; C/EBP; CCAAT/enhancer-binding protein; CD36; CD36 molecule/thrombospondin receptor;
Keywords: Doxorubicin-induced cardiomyopathy; Stem-cell transplantation; Resveratrol; Mitochondrial delivery; MITO-porter; MITO cell; OXPHOS; oxidative phosphorylation; CPC; Cardiac progenitor cell; NAD+; Â nicotinamide adenine dinucleotide; Sirt1; sirtuine1; PGC1Î
Keywords: As(III); arsenite; As(V); arsenate; MMA; monomethylarsonic acid; Nox 2; NADPH oxidase; NOS; nitric oxide synthases; ETC; electron transport chain; WAT; white adipose tissue; BAT; brown adipose Tissue; UCP; uncoupling protein; α-KDGH; α-ketoglutarate deh
Keywords: COX2; Cytochrome c oxidase subunit II; GAP 43; growth-associated protein 43; GFAP; glial fibrillary acidic protein; GLUT; glucose transporter; Iba 1; Ionized calcium binding adaptor molecule 1; KHK; ketohexokinase; MBP; Myelin Protein Basic; MetS; metabol
Keywords: Strawberry; LPS; Human Dermal Fibroblast; Inflammation; Oxidative stress; Antioxidant response; Prevention; 2-DG; 2-deoxyglucose; 2,4 DNP; 2,4-Dinitrophenol; ABB; annexin binding buffer; ABTS; 2,20-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) diammo
Keywords: Flavonoids; Quercetin; Plant-derived polyphenol; Cardiovascular action; Bioassay; CVD; Cardiovascular disease; eNOS; endothelial nitric oxide synthase; BcL2; B-cell lymphoma 2; MDA; malonaldehyde; TNFα; tumor necrosis factor α; IL-6; Interleukin 6; PPAR
Keywords: Dihydrocapsiate; HFD; Obesity; Glucose intolerance; Hepatic steatosis; ACOX1; Acyl-CoA oxidase 1; ADIPO; adiponectin; AIN; American Institute of Nutrition; ANOVA; 1-way analysis of variance; BAT; brown adipose tissue; BMI; body mass index; C/EBPβ; CCAAT/
Keywords: ABAD; Aβ binding alcohol dehydrogenase; AD; Alzheimer's disease; ADAM; A Disintegrin and metalloproteinase; AICD; APP intracellular domain; APH1; anterior pharynx-defective 1; APP; amyloid precursor protein; ATP; adenosine triphosphate; Aβ; amyloid be
Keywords: Metabolic surgery; Skeletal muscle; Glycogen synthesis; Insulin signaling; PGC1α;
Keywords: ATP; Adenosine triphosphate; OXPHOS; Oxidative phosphorylation; ROS; Reactive oxygen species; RNS; Reactive nitrogen species; TCA; Tricarboxylic acid; IR; Insulin resistance; MetS; Metabolic syndrome; ETC; Electron transport chain; SOD; Superoxide dismuta
Dietary tea polyphenols ameliorate metabolic syndrome and memory impairment via circadian clock related mechanisms
Keywords: TP; tea polyphenols; DD; constant darkness; SCN; suprachiasmatic nucleus; LD; light-dark; CLOCK; circadian locomotor output cycles kaput; BMAL1; brain and muscle arnt-like protein-1; CRY; cryptochromes; REV-ERB; -; RORs; RAR-related orphan receptors; PE
Keywords: AMPK; AMP-activated protein kinase; ATG; autophagy-related; CL; cardiolipin; EM; electron microscopy; EMC; ER membrane protein complex; ER; endoplasmic reticulum; ERMES; ER-mitochondria encounter structure; FFAT; two phenylalanines in an acid tract; HOPS;
Keywords: Bmp4; bone morphogenetic protein 4; EGCG; (-)-epigallocatechin-3-gallate; Ex; voluntary exercise; GTE; decaffeinated green tea extract; HF; high fat diet; Lipe; hormone sensitive lipase; LF; low fat; mt-Co3; cytochrome C oxidase subunit III; mt-Cytb; cyto
Keywords: FATP1; Fatty acid transport protein 1; FA; Fatty acids; MHD; Metabolic heart disease; ROS; Reactive oxygen species; PPARα; Peroxisome proliferator-activated receptor α; PGC1α; PPARγ coactivator-1 α; DG; Diacylglycerol; CREB; Cyclic AMP responsive ele
Keywords: 24OHC; 24S-Hydroxycholesterol; 27OHC; 27-Hydroxycholesterol; ABC; ATP-binding cassette transporter; ACAT; Acyl-Coa:cholesterol acyltransferase; AD; Alzheimer disease; ApoE; Apolipoprotein E; BACHD; Bacterial artificial chromosome HD; BDNF; Brain-derived n
Keywords: ACLY; ATP citrate lyase; AKT; protein kinase B; ATP; adenosine triphosphate; ANT; adenine nucleotide translocator; AMPK; AMP-activated protein kinase; COX; cytochrome c oxidase; EGFR; epidermal growth factor receptor; ERRα; estrogen-related receptor alph
Keywords: adipose-derived stem cells; ASCs; atomic force microscopy; AFM; basic fibroblast growth factors; bFGFs; body mass index; BMI; bone morphogenetic protein; BMP; brown adipose tissue; BAT; CCAAT/enhancer-binding protein; C/EBP; cyclic adenosine monophosphate
Keywords: CRBN; cereblon; I-R; ischemia-reperfusion; WT; wild-type; KO; knockout; AMPK; AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; PARP1; poly (ADP-ribose) polymerase 1; AICAR; 5-aminoimidazole-4-carboxamide 1-β-d-ribofuranoside; A-769662; a no
Keywords: AceCS2; acetyl-CoA synthetase 2; ADP; adenosine diphosphate; CPS1; carbamoyl phosphate synthetase 1; CPT1; carnitine palmitoyltransferase I; CR; calorie restriction; FOXO3a; forkhead box 03a; GDH; glutamate dehydrogenase; HeLa; human cervical carcinoma ce
Keywords: ACADl; acyl-CoA dehydrogenase, long chain; ACADm; acyl-CoA dehydrogenase, medium chain; ACADvl; acyl-CoA dehydrogenase, very long chain; AMPK; 5â² AMP-activated protein kinase; CD36; cluster of differentiation 36; CPT2; carnitine palmitoyltransferase II;
Keywords: ACTB; actin, beta; ACOX1; acyl-CoA oxidase 1; ADCYAP1R1; adenylate cyclase activating polypeptide 1 receptor 1; ADIPOQ; adiponectin C1Q and collagen domain containing; ADIPOR1; adiponectin receptor 1; ADIPOR2; adiponectin receptor 2; ADRA2B; adrenergic re
PGC1α is required for the induction of contact inhibition by suppressing ROS
Keywords: PGC1α; Cell density; Contact inhibition; ROS; SIRT3;
Melanoma metabolism contributes to the cellular responses to MAPK/ERK pathway inhibitors
Keywords: MAPK; mitogen-activated protein kinase; BRAF; v-raf murine sarcoma viral oncogene homolog B1; MEK; mitogen-activated protein/extracellular signal- regulated kinase kinase; ERK; extracellular signal-regulated kinase; HIF-1α; hypoxia inducible factor 1 alp
The CAR agonist TCPOBOP inhibits lipogenesis and promotes fibrosis in the mammary gland of adolescent female mice
Keywords: ACC; acetyl-CoA carboxylase; α-SMA; alpha-smooth muscle actin; CAR; constitutive androstane receptor; FAS; fatty acid synthase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; G6pase; glucose-6-phosphatase; Gon-WAT; gonadal white adipose tissue; H&E; he
Potential role of the mitochondria as a target for the hepatotoxic effects of (-)-epigallocatechin-3-gallate in mice
Keywords: Green tea; (-)-Epigallocatechin-3-gallate; Hepatotoxicity; Oxidative stress; Mitochondria; ALT; alanine aminotransferase; AST; aspartate aminotransferase; MT-Co2; cytochrome oxidase subunit II; EGCG; (-)epigallocatechin-3-gallate; FOXO3a; forkhead box O3a
Protection by different classes of dietary polyphenols against palmitic acid-induced steatosis, nitro-oxidative stress and endoplasmic reticulum stress in HepG2 hepatocytes
Keywords: Non-alcoholic fatty liver disease; Functional food polyphenols; Endoplasmic reticulum stress; Oxidative stress; Mitochondrial dysfunction; AMPK; AMP-activated protein kinase; ATP5G1; ATP synthase, mitochondrial Fo complex, subunit C1 (subunit 9); CCCP; ca
MITF acts as an anti-oxidant transcription factor to regulate mitochondrial biogenesis and redox signaling in retinal pigment epithelial cells
Keywords: RPE; ARPE-19; Oxidative stress; PGC1α; Retinal degeneration;
Chitosan oligosaccharides improve the disturbance in glucose metabolism and reverse the dysbiosis of gut microbiota in diabetic mice
Keywords: ACC-1; acetyl-CoA carboxylase 1; AMPK; 5Ⲡadenosine monophosphate-activated protein kinase; CD11c; integrin subunit alpha X; COS; chitosan oligosaccharides; C/EBPα; CCAAT-enhancer-binding protein alpha; GLP-1; glucagon-like peptide-1; H&E; hematoxylin
Mechanisms controlling the anti-neoplastic functions of FoxO proteins
Keywords: ATM; ataxia telangiectasia mutated; cHL; classical hodgkin lymphoma; CML; chronic myelogenous leukemia; CSC; cancer stem cell; ERK; the extracellular signal-regulated kinase; ERα; the nuclear receptor estrogen receptor α; FoxO; forkhead box O; G6PC; glu
Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury
Keywords: diabetic kidney disease; PGC1α; podocytes; SIRT1;
Impairment of energy sensors, SIRT1 and AMPK, in lipid induced inflamed adipocyte is regulated by Fetuin A
Keywords: Fetuin A; SIRT1; AMPK; PGC1α; Adipocyte; Energy homeostasis;
TRPM8 activation improves energy expenditure in skeletal muscle and exercise endurance in mice
Keywords: TRPM8; Transient receptor potential melastatin 8; UCP1; uncoupling protein 1; PGC1α; peroxisome proliferator-activated receptor-γ coactivator 1α; AMTB; N-(3-Aminopropyl)-2-[(3-methylphenyl) methoxy]-N- (2-thienylmethyl) benzamide hydrochloride salt; DM
Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice
Keywords: Fatty Liver; Gene Regulation; Hepatic Protection; Mouse Model; Ad; adenovirus; AH; alcoholic hepatitis; ALD; alcoholic liver disease; ALT; alanine aminotransferase; ATP6V0E1; ATPase H+ transporting V0 subunit E1; ATP6V1D; ATPase H+ transporting V1 subunit
High-fat diet alters PAS kinase regulation by fasting and feeding in liver
Keywords: ACC; acetyl CoA carboxylase; Akt/PKB; protein kinase B; CHREBP; carbohydrate-responsive element-binding protein; CPT1-A; carnitine palmitoyltransferase 1A; DAPI; 4,6-diamidino-2-phenylindole; FAS; fatty acid synthase; FOXO1; forkhead box protein O1; GCK;
FOXO1 cysteine-612 mediates stimulatory effects of the coregulators CBP and PGC1α on FOXO1 basal transcriptional activity
Keywords: Forkhead box transcription factors; CBP/p300; PGC1α; Glucose 6-phosphatase; Selenoprotein P; HNF4α;
YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α
Keywords: Angiogenesis; Mitochondrial biogenesis; YAP1; TEAD1; PGC1α;
A novel brown adipocyte-enriched long non-coding RNA that is required for brown adipocyte differentiation and sufficient to drive thermogenic gene program in white adipocytes
Keywords: BAT; brown adipose tissue; WAT; white adipose tissue; ETC; electron transport chain; Ucp1; uncoupling protein 1; Cebpα/β/δ; CCAAT/enhancer-binding proteins α/β/δ; Pparγ; peroxisome proliferator-activated receptor gamma; Pgc1α; Pparγ coactivator 1
Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control
Keywords: ALT; Alanine aminotransferase; Drp1; dynamin-related protein 1; EDTA; ethylenediaminetetraacetic acid; GDH; glutamate dehydrogenase; H&E; hematoxylin&eosin; HO-1; heme oxygenase-1; H/R; hypoxia/reoxygenation; IL; interleukin; I/R; ischemia/reperfusion; LP
FLCN: The causative gene for Birt-Hogg-Dubé syndrome
Keywords: AEC; alveolar epithelial type II cell; AKT; protein kinase B; AMPK/Ampk; 5â²-AMP activated protein kinase; AMPKα (also AAK-2); AMPKα subunit; ATP; adenosine triphosphate; Bcl-2; B-cell lymphoma 2; BHD; Birt-Hogg-Dubé; BAT; brown adipose tissue; C. ele
AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis
Keywords: Melatonin; Doxorubicin; Mitochondria; Apoptosis; Cardiotoxicity; AMPK; PGC1α;
Heme oxygenase-1 induction by rosiglitazone via PKCα/AMPKα/p38 MAPKα/SIRT1/PPARγ pathway suppresses lipopolysaccharide-mediated pulmonary inflammation
Keywords: Rosiglitazone (PubChem CID: 77999); Lipopolysaccharide (PubChem CID: 11970143); H7 (PubChem: 11957580); Gö6976 (PubChem: 3501); Compound C (PubChem: 11524144); p38VIII (PubChem: 9801969); Sirtinol (PubChem: 5717148); T0070907 (PubChem: 2777391); AMPKα;
The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review
Keywords: AM; Atractylodes macrocephala Koidz.; TCM; traditional Chinese medicine; UPLC; ultra-performance liquid chromatography; PDA; photo-diode array; IR; infrared spectroscopy; HS-LP-LPE; headspace liquid phase-liquid-phase extraction; GC-MS; gas chromatography
Adipocytes spectrum - From homeostasia to obesity and its associated pathology
Keywords: Acrp30 (AdipoQ); adiponectin gene; AdipoR; adiponectin receptor; AGE; angiotensinogen; ALP; alkaline phosphatase; Ang II; angiotensin II; Angptl2; angiopoietin-like protein-2; Aqp7; aquaporin-7; aP2; adipocyte-specific fatty acid binding protein 2 gene; A
AHR toxicity and signaling: Role of TIPARP and ADP-ribosylation
Keywords: Aryl hydrocarbon receptor; 2,3,7,8-Tretrachlorodibenzo-p-dioxin; ADP-ribosylation; TCDD-inducible poly-ADP-ribose polymerase; AHR; aryl hydrocarbon receptor; AHRE; AHR response element; ARH; ADP-ribosyl hydrolases; ARNT; AHR nuclear translocator; ARTD; AD
Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma
Keywords: AMPK; AMP-activated kinase; BRAFi; BRAF inhibitor; ERK; extracellular signal-regulated kinase; ERKi; ERK inhibitor; PGC1α; peroxisome proliferator-activated receptor gamma, coactivator 1-α; MEK; MAPK/ERK kinase; MEKi; MEK inhibitor; mTOR; mechanistic ta
Genipin protects the liver from ischemia/reperfusion injury by modulating mitochondrial quality control
Keywords: IR; Ischemia and reperfusion; QC; quality control; ROS; reactive oxygen species; ALT; alanine aminotransferase; H&E; hematoxylin and eosin; GDH; glutamate dehydrogenase; ELISA; enzyme-linked immunosorbent assay; PGC1α; proliferator-activated receptor-gam
EGCG ameliorates diet-induced metabolic syndrome associating with the circadian clock
Keywords: EGCG; Epigallocatechin gallate; CLOCK; Circadian locomotor output cycles kaput; BMAL1; Brain and muscle arnt-like protein-1; CRY; Cryptochromes; PER; Period; SIRT1; Sirtuin 1; PGC1α; Peroxisome proliferator-activated receptor coactivator 1-α; IR; Insuli