Keywords: فسفوگلسرات ماتاز 1; 2-DE; two-dimensional gel electrophoresis; CNS; central nervous system; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; GS; glutamine synthetase; HIF-1; hypoxia-inducible factor 1; HSP71; heat-shock protein 71Â kDa;