دانلود مقالات ISI درباره Plcβ + ترجمه فارسی

یک مرور کلی بر عملکرد بیولوژیکی و نقش های درمانی آپلین در دیابت

An overview on biological functions and emerging therapeutic roles of apelin in diabetes mellitus

Keywords: T2DM; Type 2 diabetes mellitus; WAT; White adipose tissue; APJ; angiotensin II protein J receptor; GPCRs; G-protein couple receptors; DN; diabetic nephropathy; WHO; World Health Organization; T2DM; type 2 diabetes mellitus; CVD; cardiovascular disease; BM

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

هدفون سلول های مشت: کشف نقش درمان دارویی در بیماری های بی شماری

Targeting mast cells: Uncovering prolific therapeutic role in myriad diseases

Keywords: AP1; Activator protein 1; cAMP; Cyclic adenosine monophoshate; CXCR; Cytokine receptors; CRTH2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; DAMPs; Damage-associated molecular pattern; EtBr; Ethidium Bromide; IgE; Immunoglobulin E;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Selective inhibition of histamine-evoked Ca2+ signals by compartmentalized cAMP in human bronchial airway smooth muscle cells

Keywords: AC; adenylyl cyclase; 2-APB; 2-aminoethoxyphenylborane; ASM; airway smooth muscle; cAMP; 3',5'-cyclic AMP; COPD; chronic obstructive pulmonary disease; [Ca2+]i; intracellular free Ca2+ concentration; DMSO; dimethyl sulfoxide; EC50 (IC50); half-maximally e

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Differential roles of PKC isoforms (PKCs) in GnRH stimulation of MAPK phosphorylation in gonadotrope derived cells

Keywords: GnRH; PKCα; PKCβII; PKCδ; PKCε; MAPK; ERK; JNK; p38; Gonadotropes; LβT2 cells; αT3-1 cells; anti-DP antibodies; anti-diphospho-antibodies; DAG; diacylglycerol; DN; dominant negative; ERK; extracellular signal-regulated kinase; FSH; follicle stimula

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension

Keywords: ADRF; adipocyte-derived relaxing factor; AE; anion exchanger; ATP; adenosine triphosphate; BH4; tetrahydrobiopterin; BKCa; big conductance Ca2+-sensitive K+ channel; CaM; calmodulin; cAMP; cyclic adenosine monophosphate; CAT; cysteine aminotransferase; CB

دانلود رایگان متن کامل مقاله ISI 88 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of transient receptor potential canonical 1 (TRPC1) on the mechanical stretch-induced expression of airway remodeling-associated factors in human bronchial epithelioid cells

Keywords: IL-13; interleukin-13; MMP-9; matrix metalloprotein-9; HBE; human bronchial epithelioid; TRPC1; transient receptor potential canonical 1; COPD; chronic obstructive pulmonary disease; PIP2; phosphatidylinositol-4, 5-bisphosphate; PKC; protein kinase C; ATC

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases

Keywords: ADP; adenosine 5′-diphosphate; AgRP; agouti-related peptide; AMPK; 5′-AMP-activated protein kinase; ApnA; diadenosine polyphosphate; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATP; adenosine 5′-triphosphate; BN-PAGE; blue native-p

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Mechanisms that underlie the internalization and extracellular signal regulated kinase 1/2 activation by PKR2 receptor

Keywords: AT1AR; angiotensin type 1A receptor; ConA; Concanavalin A; DN-GRK; dominant-negative G-protein-coupled receptor kinase 2; EGFP; enhanced green fluorescent protein; ERK; extracellular signal regulated kinase; GPCR; G-protein-coupled receptors; GRK; GPCR ki

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Ginsenoside Rg1 inhibits platelet activation and arterial thrombosis

Keywords: COX; cyclooxygenase; CDDPs; Compound Danshen Dripping Pills; SAA; salvianolic acid A; PNS; panax notoginsenosides; Rg1; ginsenoside Rg1; PARs; proteinase-activated receptors; PLCβ; phospholipase C β; PKC; protein kinase C; MAPKs; mitogen-activated prote

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Crystal structure of phospholipase PA2-Vb, a protease-activated receptor agonist from the Trimeresurus stejnegeri snake venom

Keywords: PLA2; phospholipases A2; PAR-1; protease-activated receptor 1; IP3R; inositol 1,4,5-trisphosphate receptor; svPLA2; snake venom PLA2; VSMCs; vascular smooth muscle cells; SR; sarcoplasmic reticulum; RyR; ryanodine receptor; GPCRs; G-protein coupled recept

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Loss of regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation

Keywords: Asthma; airway hyperresponsiveness; G proteins; regulator of G protein signaling proteins; Aspergillus fumigatus; AHR; Airway hyperresponsiveness; ASM; Airway smooth muscle; BALF; Bronchoalveolar lavage fluid; DAPI; 4′-6-Diamidino-2-phenylindole dihydro

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Differential regulation of chemotaxis: Role of Gβγ in chemokine receptor-induced cell migration

Keywords: CHO; Chinese hamster ovary; CCL3; Chemokine ligand 3; CCR5; Chemokine receptor 5; DMEM; Dulbecco's modified Eagle's medium; EDTA; Ethylenediaminetetraacetic acid; ERK; Extracellular signal-regulated kinases; FCS; Foetal calf serum; GPCR; G protein coupled

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq

Keywords: PLCβ; Gαq; FRET; Chemical dimerizers;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Activation of Gαq subunits up-regulates the expression of the tumor suppressor Fhit

Keywords: GRPR; gastrin-releasing peptide receptor; BK2R; bradykinin type 2 receptor; β2AR; β2 adrenergic receptor; MT1R; melatonin type 1 receptor; CHX; cycloheximide; eIF; eukaryotic initiation factor; 4EBP1; eIF4E binding protein 1; RGS; regulator of G protein

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2013 سفارش ترجمه

Scaffold protein Homer 1: Implications for neurological diseases

Keywords: EVH1; Enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) homology 1; IEG; immediate-early gene; P motif; proline-containing motif; mGluR; metabotropic glutamate receptor; IP3R; inositol 1,4,5-trisphosphate receptor; TRPC; transient receptor potentia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Cellular and Molecular NeuroscienceResearch PaperMembrane depolarization combined with Gq-activated G-protein-coupled receptors induce transient receptor potential channel 1 (TRPC1)- dependent potentiation of catecholamine release

Keywords: Ca2+ channel; TRPC channel; Gq/11 GPCR; PLCβ; depolarization-evoked secretion; LTP; BK; bradykinin; CA; catecholamine; GPCRs; G-protein-coupled receptors; Hist; histamine; IP3; inositol trisphosphate; K60; 60 mM KCl; LTP; long-term potentiation; PI; phos

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Negative regulation of Ca2+ influx during P2Y2 purinergic receptor activation is mediated by Gβγ-subunits

Keywords: GPCR; heptahelical G protein-coupled receptor; βARK; β-adrenergic receptor kinase; Gα; α-subunit of G protein; Gβγ; βγ-subunits of the G protein; Ad-MX17; adenovirus that contains only virus backbone; Ad-EF1-wtGαq; adenovirus expressing α-subuni

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Gα16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS)

Keywords: ERK; extracellular signal-regulated kinase; GPCRs; G protein-coupled receptors; HEK 293; human embryonic kidney 293; IKK; IκB kinase; NFκB; nuclear factor κB; PLCβ; phospholipase Cβ; STAT3; signal transducer and activator of transcription 3; TPR1; te

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Pain signalling pathways: From cytokines to ion channels

Keywords: NGF; nerve growth factor; TNFα; tumor necrosis factor α; IL-Iβ; interleukin 1β; PLCβ; phospholipase Cβ; PLA2; phospholipase A2; PKC; protein kinase C; TTX-R; tetrodotoxin-resistant; AA; arachidonic acid; PGE2; prostaglandin E2; COX; cyclooxygenase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Human adenosine A3 receptor leads to intracellular Ca2+ mobilization but is insufficient to activate the signaling pathway via phosphoinositide 3-kinase γ in mice

Keywords: A3AR; adenosine A3 receptor; A3ARh/h mice; A3AR-humanized mice; BMMCs; bone marrow-derived mast cells; [Ca2+]i; intracellular Ca2+ concentration; Cl-IB-MECA; 2-chloro-N6-(3-iodobenzyl)adenosine-5′-N-methyluronamide; DT-A; diphtheria toxin A fragment; EP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular responses to acidosis of central chemosensitive neurons in brain

Keywords: ASIC; acid-sensing ionic channel; AP-1; activator protein 1; ATF-2; activating transcription factor-2; bZIP; basic leucine zipper; Ca2+/CaM; Ca2+/calmodulin; CRE; cyclic AMP response element; ERK; extracellular signal-regulated kinase; GLUT; glucose trans

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه