دانلود مقالات ISI درباره پلی (ADP-ribose) پلیمراز + ترجمه فارسی

فعال کننده پلاسمینوژن بافت بازمتنژن، آزادسازی میکرواستراتژی از سلولهای اندوتلیال مغز موش از طریق پلاسمین را افزایش می دهد

Recombinant tissue plasminogen activator enhances microparticle release from mouse brain-derived endothelial cells through plasmin

Keywords: پلی (ADP-ribose) پلیمراز; APC; allophycocyanin; BBB; blood brain barrier; DAPI; 4′,6-diamidino-2-phenylindole; EMPs; endothelial microparticles; FITC; fluorescein isothiocyanate; ICAM-1; intercellular cell adhesion molecule; LDH; lactate dehydrogenase; LRP; lipoprotein receptor-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

STAT3 contributes to lysosomal-mediated cell death in a novel derivative of riccardin D-treated breast cancer cells in association with TFEB

Keywords: پلی (ADP-ribose) پلیمراز; STAT3; signal transducers and activators of transcription 3; RD-N; Riccardin D-N; CTSB; cathepsin B; LMP; lysosomal membrane permeabilization; LAMP1; lysosome associated membrane protein 1; LM-PCD; lysosomal-mediated programme of cell death; AO; acridine

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Focusing on claudin-5: A promising candidate in the regulation of BBB to treat ischemic stroke

Keywords: پلی (ADP-ribose) پلیمراز; 5α-DHP; 5α-dihydroprogestrone; ABC; ATP-binding cassette; AF6; ALL-1-fused gene from chromosome 6; ALL; acute lymphoblastic leukemia; AMPAR; amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor; Ang-1; angiopoietin-1; AP-1; activator protein-1; BBB;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Integrating plant and animal biology for the search of novel DNA damage biomarkers

Keywords: پلی (ADP-ribose) پلیمراز; ARP; actin related protein; ASK; Arabidopsis SPK1-like; At; Arabidopsis thaliana; ATAF; arabidopsis transcription activation factor; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR-interacting protein; BARD; BRCA1-associated RING

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors

Keywords: پلی (ADP-ribose) پلیمراز; Tankyrase inhibitors; PARP family; Wnt/β-catenin signaling pathway; Wnt pathway disruption; Wnt-driven cancers; APC; adenomatous polyposis coli gene product; ARTD; ADP-ribosyltransferases; CK1; casein kinase 1; DMPK; drug metabolism and pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

DNA maintenance following bleomycin-induced strand breaks does not require poly(ADP-ribosyl)ation activation in Drosophila S2 cells

Keywords: پلی (ADP-ribose) پلیمراز; PARP; poly(ADP-ribose)polymerase; PARG; poly(ADP-ribose)glycohydrolase; PAR; poly(ADP-ribosyl)ation; SSB; single-strand break; DSB; double-strands break; DNA repair; DNA breaks; PARP; Poly(ADP-ribosyl)ation; PARG;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Expression level of P2X7 receptor is a determinant of ATP-induced death of mouse cultured neurons

Keywords: پلی (ADP-ribose) پلیمراز; DIV; days in vitro; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; MAP2; microtubule-associated protein 2; mPTP; mitochondrial permeability transition pore; PARP; poly(ADP-ribose)polymerase; ATP; P2X7 receptor; neu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases

Keywords: پلی (ADP-ribose) پلیمراز; Tankyrase; PARP; 2-Arylquinazolin-4-one; Wnt; Hydrophobic cavity; ADP; adenosine diphosphate; Bn; benzyl; Cbz; benzyloxycarbonyl; DMAP; 4-dimethylaminopyridine; EDC; N′-ethyl-N-3-(dimethylaminopropyl)carbodiimide; ES; electrospray; HMBC; heteronuclear m

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Paeonia japonica root extract protects hepatocytes against oxidative stress through inhibition of AMPK-mediated GSK3β

Keywords: پلی (ADP-ribose) پلیمراز; AA; arachidonic acid; ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; 4EBP-1; eIF-4E binding protein 1; FACS; fluorescence-a

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

PARP-1 involvement in neurodegeneration: A focus on Alzheimer's and Parkinson's diseases

Keywords: پلی (ADP-ribose) پلیمراز; Alzheimer's disease; Parkinson's disease; Poly(ADP-ribose)polymerase; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors

Keywords: پلی (ADP-ribose) پلیمراز; Enzyme; Activity assay; Inhibitor; High-throughput screening; Poly(ADP-ribose)polymerase; ADP-ribosyltransferase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Expression and activity of PARP family members in the hippocampus during systemic inflammation: Their role in the regulation of prooxidative genes

Keywords: پلی (ADP-ribose) پلیمراز; Systemic inflammation; Inflammatory reaction; Neuroinflammation; Oxidative stress; Poly(ADP-ribose)polymerase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Prevention of rt-PA induced blood-brain barrier component degradation by the poly(ADP-ribose)polymerase inhibitor PJ34 after ischemic stroke in mice

Keywords: پلی (ADP-ribose) پلیمراز; PARP; Poly(ADP-ribose)polymerase; PJ34; N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride; rt-PA; recombinant tissue plasminogen activator; Hemorrhagic transformation; Blood-brain barrier; Recombinant tissue plasminogen

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Synthetic menthyl α/β-(1→6)-diglucopyranosides-induced cell death in human leukemia cells is dependent on caspases

Keywords: پلی (ADP-ribose) پلیمراز; Apoptosis; Carbohydrates; Caspases; Poly(ADP-ribose)polymerase; Reactive oxygen species

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus leaves

Keywords: پلی (ADP-ribose) پلیمراز; AIF; apoptosis inducing factor; CDK; cyclin-dependent kinase; EGFR; epidermal growth factor receptor; HUVEC; human umbilical vein endothelial cells; PARP; poly(ADP-ribose)polymerase; PDGFR; platelet derived growth factor receptor; pH3Ser10; phosphorylated

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The BRCA1 alternative splicing variant Δ14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells

Keywords: پلی (ADP-ribose) پلیمراز; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; AURKA; Aurora kinase A; BC; breast cancer; BRCA1/2; breast cancer-associated gene 1/2; BRCT; BRCA1 C-terminal domain; B2M; beta-2-microglobulin; Cdk2; cyclin-dependent kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The role of mitochondria-mediated intrinsic death pathway in gingerdione derivative I6-induced neuronal apoptosis

Keywords: پلی (ADP-ribose) پلیمراز; I6; 1-(3,4-dimethoxyphenyl)-3,5-dodecenedione; Vit E; vitamin E; NAC; N-acetylcysteine; ROS; reactive oxygen species; PARP; poly(ADP-ribose)polymerase; H2DCFDA; 2′,7′-dichlorodihydrofluorescein diacetate; FCCP; carbonyl cyanide p-(trifluoromethoxy)phe

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization and role of poly(ADP-ribosyl)ation in the Mediterranean species Cistus incanus L. under different temperature conditions

Keywords: پلی (ADP-ribose) پلیمراز; Cistus incanus L.; Poly(ADP-ribose)polymerase; Poly(ADP-ribose)glycohydrolase; Photochemical efficiency; Photosystem II; Low temperature; ADPR; adenosine diphosphate ribose; Fm; maximal fluorescence level in the dark-adapted state; Fm′; maximal fluoresc

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)

Keywords: پلی (ADP-ribose) پلیمراز; PARP-1; Poly(ADP-ribose)polymerase; Quinoxalinone; Nuclear enzyme; DNA repair; Programmed cell death; Nicotinamide;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Cell death in the injured brain: Roles of metallothioneins

Keywords: پلی (ADP-ribose) پلیمراز; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolyl-propionic acid; Apaf-1; apoptotic protease-activating factor 1; Atg; autophagy gene; Bak; Bcl-2-homologous antagonist/killer; Bax; Bcl-2-associated

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2009 سفارش ترجمه

Upregulation of PEDF expression by PARP inhibition contributes to the decrease in hyperglycemia-induced apoptosis in HUVECs

Keywords: پلی (ADP-ribose) پلیمراز; Poly(ADP-ribose)polymerase; Angiogenesis; Vascular endothelium growth factor; Pigment epithelium-derived factor; p38 MAP kinase; Apoptosis; Antisense oligonucleotide

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Keywords: پلی (ADP-ribose) پلیمراز; Poly(ADP-ribose)polymerase; PARP inhibitor; A-620223; Benzimidazole carboxamide

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis and structure–activity relationships of novel pyrrolocarbazole lactam analogs as potent and cell-permeable inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)

Keywords: پلی (ADP-ribose) پلیمراز; Poly(ADP-ribose)polymerase; Pyrrolocarbazole; Lactam; DNA repair; Cancer

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

IGF-I-induced VEGF expression in HUVEC involves phosphorylation and inhibition of poly(ADP-ribose)polymerase

Keywords: پلی (ADP-ribose) پلیمراز; Insulin-like growth factor-I; Vascular endothelial growth factor; Poly(ADP-ribose)polymerase; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

The polymorphisms of GSTM1, GSTT1, HYL1*2, and XRCC1, and aflatoxin B1-related hepatocellular carcinoma in Guangxi population, China

Keywords: پلی (ADP-ribose) پلیمراز; AFB1; aflatoxin B1; BER; base excision repair; GST; glutathione S-transferase; HCC; hepatocellular carcinoma; HYL1; microsomal epoxide hydrolase; HYL1*2-YY; the wild homozygote of HYL1*2; HYL1*2-YG/HH; HYL1*2 genotypes with 113 His allele; PARP; poly(ADP-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Targeted Disruption of FANCC and FANCG in Human Cancer Provides a Preclinical Model for Specific Therapeutic Options

Keywords: پلی (ADP-ribose) پلیمراز; DEB; diepoxybutane; FA; Fanconi anemia; ICL; DNA interstrand-crosslink; IR; ionizing radiation; KO; knockout; MMC; mitomycin C; PCR; polymerase chain reaction; IC50; the concentration of a drug producing 50% inhibition of growth in vitro; PARP; poly(ADP-r

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae

Keywords: پلی (ADP-ribose) پلیمراز; GNS; gluconasturtiin; GRA; glucoraphanin; IC50; half-maximal inhibitory concentration; Myr; myrosinase; PARP; poly(ADP-ribose)polymerase; PEITC; β-phenethyl isothiocyanate; Isothiocyanates; Indoles; Apoptosis; Caspases; Colon cancer; Bcl-2 family protein

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Enhanced anticancer efficacy of α-tocopheryl succinate by conjugation with polyethylene glycol

Keywords: پلی (ADP-ribose) پلیمراز; TOS; α-tocopheryl succinate; PEG; polyethylene glycol; TPGS; alpha-tocopheryl polyethylene glycol succinate; PARP; poly(ADP-ribose)polymerase; DCFH; 2′,7′-dichloro-dihydrofluorescein; ROS; reactive oxygen species; α-tocopheryl succinate; Polyethylen

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

High effectiveness of platinum(IV) complex with adamantylamine in overcoming resistance to cisplatin and suppressing proliferation of ovarian cancer cells in vitro

Keywords: پلی (ADP-ribose) پلیمراز; cis-DDP; cis-diamminedichloroplatinum(II); LA-12; (OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloroplatinum(IV); JM216; (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum(IV); cisplatin (50 or 90); LA-12 (50 or 90), IC50 or IC90 drug conce

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Vitamin D sensitizes breast cancer cells to the action of H2O2: Mitochondria as a convergence point in the death pathway

Keywords: پلی (ADP-ribose) پلیمراز; 3-ABA; 3-aminobenzamide; Ac-DEVD-AMC; Ac-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin; CCCP; carbonyl cyanide m-chlorophenylhydrazone; CV; crystal violet; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethyl sulfoxide; DNP; 2,4-dinitrophenol; GAPDH; glycera

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

PKC 412 sensitizes U1810 non-small cell lung cancer cells to DNA damage

Keywords: پلی (ADP-ribose) پلیمراز; AIF; apoptosis-inducing factor; AMC; 7-amino-4-methylcoumarin; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; DEVD; Asp-Glu-Val-Asp; DTT; dithiothreitol; ERK1/2; extracellular signal-regulated kinase 1/2; FIGE; field inversion gel elect

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Synergistic activation of JNK/SAPK induced by TNF-α and IFN-γ: Apoptosis of pancreatic β-cells via the p53 and ROS pathway

Keywords: پلی (ADP-ribose) پلیمراز; JNK/SAPK; c-jun NH2-terminal kinase/stress-activated protein kinase; ROS; reactive oxygen species; ΔΨm; mitochondrial transmembrane potential; NAC; N-acetyl-l-cysteine; MTT; 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide; DCFH-DA; dichlor

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2005 سفارش ترجمه