Keywords: گروه پلی کامب; BCL-2; B-cell lymphoma 2; CA-125; cancer antigen-125; CAFs; cancer-associated fibroblasts; CCL17; chemokine (C-C motif) ligand 17; CCL2; chemokine (C-C motif) ligand 2; CXCL12; chemokine (C-X-C motif) ligand 12; DFS; disease-free survival; DNMT; DNA methy
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Keywords: گروه پلی کامب; LPS; lipopolysaccharide; PcG; polycomb group; PRC; polycomb repressive complex; TLR; toll-like receptor; TrxG; trithorax group; Ischemia; Seizure; Neuroprotection; Epigenetic regulation; PcG proteins; DNA methylation;
Keywords: گروه پلی کامب; GnRH neurons; Kisspeptin neurons; Female puberty; Chromatin modifications; DNA methylation; Transcriptional repression; Transcriptional activation; Epigenetic regulators; microRNAs; Long noncoding RNAs; 5hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosin
Keywords: گروه پلی کامب; Epigenetic modifiers; Chromatin; Therapy; Cancer; Histone profiles; ac; acetyl; ATRA; all-trans retinoic acid; BrD; bromodomain; FL; follicular lymphoma; H; histone; HAT; histone acetyltransferase; HDAC; histone deacetylase; HMT; histone methyltransferase
Keywords: گروه پلی کامب; 4-HPR; N-(4-hydroxyphenyl)retinamide; 5â²-UTR; 5â²-untranslated region; 9-cis-RA; 9-cis retinoic acid; 9cUAB30; (2E,4E,6Z,8E)-8-(3â²,4â²-dihydro-1â²(2'H)-naphthalen-1â²-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid; Acitretin; (2E,4E,6E,8E)-9-(4-met
Keywords: گروه پلی کامب; ARF; alternative reading frame; αSMA; alpha smooth muscle actin; CDK; cyclin-dependent kinase; DDR; DNA damage response; ECM; extracellular matrix; EMT; epithelial mesenchymal transition; FGF; fibroblast growth factor; HDAC; histone deacetylase; HIC1; hy
Keywords: گروه پلی کامب; 3C; chromosome conformation capture; Abd-B; Abdominal-B; AGO2; Argonaute 2; ANT-C; Antennapedia complex; BEAF-32; boundary element-associated factor of 32Â kDa; BTB; broad-complex, tramtrack, bric-a-brac; BX-C; bithorax complex; ChIP; chromatin immunoprec
Effects of microRNAs on skeletal muscle development
Keywords: گروه پلی کامب; HDAC4; histone deacetylase 4; SRF; serum response factor; Pax3; paired box protein pax-3; Pax7; paired box protein pax-7; 3â²UTR; 3â² untranslated region; MEF2A; myocyte-specific enhancer factor 2A; Mef2d; myocyte-specific enhancer factor 2D; Myf5; myog
Double sword role of EZH2 in leukemia
Keywords: گروه پلی کامب; EZH1,2; enhancer of Zeste 1 and 2; SUZ12; suppressor of zeste 12 homolog; EED; embryonic ectoderm development; AEBP2; adipocyte enhancer-binding protein 2; RBAP46/48; retinoblastoma binding proteins 46 and 48; PRC; polycomb-repressive complex; PcG; Polyco
Epigenetic and non-epigenetic functions of the RYBP protein in development and disease
Keywords: گروه پلی کامب; RYBP; ring1 and ying yang 1 binding protein; dRYBP; drosophila ring1 and ying yang 1 binding protein; PcG; polycomb group; trxG; trithorax group; PRC1/2; polycomb repressive complex 1/2; PHO/YY1; polyhomeotic/ying yang 1; PRE; polycomb response element; T
BMI1 and PTEN are key determinants of breast cancer therapy: A plausible therapeutic target in breast cancer
Keywords: گروه پلی کامب; HDAC i; histone deacetylase inhibitors; PcG; polycomb group; PRC1; polycomb repressive complex 1; PRC2; polycomb repressive complex 2; Bmi1; B lymphoma Mo-MLV insertion region homolog; EMT; epithelial to mesenchymal transition; PTEN; phosphatase and tensi
Introduction of novel splice variants for CASC18 gene and its relation to the neural differentiation
Keywords: گروه پلی کامب; EST; primary expressed sequence tag; lncRNAs; long non-coding RNAs; FBS; fetal bovine serum; RA; retinoic acid; PcG; Polycomb group; CASC18 gene; Long non-coding RNA; NT2 differentiation, Oct4-A gene;
Insights into the Establishment of Chromatin States in Pluripotent Cells from Studies of X Inactivation
Keywords: گروه پلی کامب; TE; trophectoderm lineage; ICM; inner cell mass; ES; embryonic stem; PcG; Polycomb group; XCI; X chromosome inactivation; Xi; inactive X chromosome; Xist; X-inactive specific transcript; E; embryonic day; animal development; pluripotent stem cell; chromat
CommunicationPolycomb Group Gene E(z) Is Required for Spermatogonial Dedifferentiation in Drosophila Adult Testis
Keywords: گروه پلی کامب; GSC; germline stem cell; GB; gonialblast; CySC; cyst stem cell; PcG; Polycomb group; PRC; Polycomb repressive complex; E(z); Enhancer of Zeste; H3K27me3; Histone H3 lysine 27 trimethylation; WT; wild-type; ACI; after clonal induction; Bam; Bag-of-marbles;
BMI1 and MEL18 Promote Colitis-Associated Cancer in Mice via REG3B and STAT3
Keywords: گروه پلی کامب; PcG; Colon Cancer; Ulcerative Colitis; PAP; AOM; azoxymethane; BMI1; BMI1 proto-oncogene, polycomb ring finger; BrdU; 5-bromo-2-deoxyuridine; CAC; colitis-associated cancer; ChIP; chromatin immunoprecipitation; Co-IP; co-immunoprecipitation; DSS; dextran
The Epigenetic Paradox of Pluripotent ES Cells
Keywords: گروه پلی کامب; TF; transcription factor; ES; embryonic stem; PcG; Polycomb Group; PRC; polycomb repressive complex; ERV; endogenous retrovirus; LTR; long terminal repeat; LINE; long interspersed elements; Brg1; Brahma-related gene 1; MLL; mixed lineage leukaemia; Ash2;
Compositional and functional diversity of canonical PRC1 complexes in mammals
Keywords: گروه پلی کامب; bps; base pairs; PcG; Polycomb Group; PRC1; Polycomb Repressive Complex 1; PRC2; Polycomb Repressive Complex 2; Pc; Polycomb; Ph; Polyhomeotic; Psc; Posterior sex combs; Sce; Sex combs extra; H3K27me3; histone H3 lysine 27 trimethylation; SAM; sterile alp
Gene-regulatory networks controlling inflorescence and flower development in Arabidopsis thaliana
Keywords: گروه پلی کامب; TF; transcription factor; MADS; MCM1, AGAMOUS, DEFICIENS, SRF; SEP; SEPALLATA; ChIP-seq; chromatin immunoprecipitation followed by deep sequencing; PcG; Polycomb group; H3K27me3; histone 3 lysine 27 tri-methylation; PRC; polycomb repressive complex; trxG;
OsSET7, a homologue of ARABIDOPSIS TRITHORAX-RELATED protein that plays a role in grain elongation regulation in rice
Keywords: گروه پلی کامب; ATXR; ARABIDOPSIS TRITHORAX-RELATED; BiFC; Bimolecular Fluorescence Complementation; CDS; coding sequence; HKMT; Histone Lysine Methyltransferase; SET; Suppressor of variegation, Enhancer of zeste and Trithorax; PcG; Polycomb Group; PCNA; Proliferating Ce
AUTS2 in the nucleus accumbens is essential for heroin-induced behavioral sensitization
Keywords: گروه پلی کامب; AUTS2; autism susceptibility candidate 2; CPu; caudate-putamen; NAc; nucleus accumbens; PcG; polycomb group; PRC; polycomb repressive complex; autism susceptibility candidate 2; nucleus accumbens; behavioral sensitization;
Aberrant differential expression of EZH1 and EZH2 in Polycomb repressive complex 2 among B- and T/NK-cell neoplasms
Keywords: گروه پلی کامب; EZH2; EZH1; EED; SUZ12; Polycomb group
Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells
Keywords: گروه پلی کامب; Small Intestine; Development; ISC; PRC1; βNF; β-naphthoflavone; CBC; crypt base columnar; ChIP; chromatin immunoprecipitation; CGI; CpG island; CM; conditioned medium; Eed; embryonic ectoderm development; Ezh1/2; enhancer of zeste homolog 1/2; FC; fold
The Bmi-1 helix-turn and ring finger domains are required for Bmi-1 antagonism of (â) epigallocatechin-3-gallate suppression of skin cancer cell survival
Keywords: گروه پلی کامب; Bmi-1; B-cell-specific Moloney murine leukemia virus integration site 1; HT; helix-turn; RF; ring finger; Ezh2; enhancer of zeste homolog 2; PcG; polycomb group; H2AK119ub; histone H2A ubiquitinated on lysine 119; H3K27me3; histone H3 trimethylation on
Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus
Keywords: گروه پلی کامب; PcG; polycomb group; EZH2; enhancer of zeste homolog 2; shRNA; short hairpin RNA; Rb; retinoblastoma; MDM2; murine double minute 2; CDKIs; cyclin-dependent kinase inhibitors; PRC1; polycomb repressive complex 1; PRC2; polycomb repressive complex 2; H3K27m
ReviewSchizophrenia: Evidence implicating hippocampal GluN2B protein and REST epigenetics in psychosis pathophysiology
Keywords: گروه پلی کامب; BDP; psychotic bipolar disorder; CK1; casein kinase 1; DG; dentate gyrus; HC; healthy controls; HDACs; histone deacetylases; MeCP2; methyl CpG binding protein 2; MR; magnetic resonance; NMDA; N-methyl-d-aspartate; NMDAR; NMDA receptor; PcG; polycomb group
Redox-regulated fate of neural stem progenitor cells
Keywords: گروه پلی کامب; ARE; antioxidant response element; bHLH; basic helix-loop-helix; BMI1; B lymphoma Mo-MLV insertion region 1 homolog; CtBPs; C-terminal binding proteins; DLL4; delta-like protein 4; DVL; disheveled; DOUX; dual oxidases; ES; embryonic stem cells; EGFR; epid
Research ArticleThe functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma
Keywords: گروه پلی کامب; HCC; hepatocellular carcinoma; PcG; polycomb group; H3K27me3; histone 3 lysine 27 trimethylation; EZH2; enhancer of zeste homolog 2; SUZ12; suppressor of zeste 12; TrxG; trithorax group; MLL; mixed-lineage leukemia proteins; MEN1; multiple endocrine neopl
CBX8, a component of the Polycomb PRC1 complex, modulates DOT1L-mediated gene expression through AF9/MLLT3
Keywords: گروه پلی کامب; CTD; carboxy-terminal domain; ChIP; chromatin immunoprecipitation; H3K79; histone 3 lysine 79; PcG; polycomb group; PRC1; PcG repressive complex 1; qRT-PCR; quantitative reverse transcriptase polymerase chain reaction; shRNA; short-hairpin RNA; Polycomb-g
Imprinting in Plants and Its Underlying Mechanisms
Keywords: گروه پلی کامب; DNA methylation; Imprinting; Polycomb group; Endosperm; Small RNA
RING1B ubiquitination and stability are regulated by ARF
Keywords: گروه پلی کامب; ARF; alternate reading frame; CDKN2A; cyclin-dependent kinase inhibitor 2A; CHX; cycloheximide; COMMD1; copper metabolism gene MURR1 domain 1; E6-AP; E6-associated protein; MDM2; mouse double minute 2; NIAM; nuclear interactor of ARF and MDM2; PcG; polyco
The PWAPA cassette: Intimate association of a PHD-like finger and a winged-helix domain in proteins included in histone-modifying complexes
Keywords: گروه پلی کامب; Sequence analysis; Protein domain; Histone post-translational modifications; PcG; TrxG; ATAC; ASH2; Absent, small or homeotic discs-like 2; ATAC2; ADA2-containing complex; DSB; double strand break; EH; Extended Homology; HAT; histone acetyltransferase; HC
Epigenetic reprogramming during tissue regeneration
Keywords: گروه پلی کامب; Epigenetic gene control; Polycomb group; Bivalent chromatin; Imaginal disc; Limb regeneration
Genetic Polymorphisms in the Polycomb Group Gene EZH2 and the Risk of Lung Cancer
Keywords: گروه پلی کامب; EZH2; Single nucleotide polymorphism; Lung cancer; Polycomb group
Cell cycle defects in polyhomeotic mutants are caused by abrogation of the DNA damage checkpoint
Keywords: گروه پلی کامب; Syncytial embryo; DNA damage response; S phase; Polycomb group;
Research ArticleThe polycomb group gene product Ezh2 regulates proliferation and differentiation of murine hepatic stem/progenitor cells
Keywords: گروه پلی کامب; PcG; polycomb group; PRC; polycomb repressive complex; H3K27; histone H3 at lysine 27; HCC; hepatocellular carcinoma; ED; embryonic day; EHS; Engelbreth-Holm-Swarm; OSM; oncostatin M; TNF; tumour necrosis factor; shRNA; short-hairpin RNA; ERP; enhance
Bmi1 deficient neural stem cells have increased Integrin dependent adhesion to self-secreted matrix
Keywords: گروه پلی کامب; Polycomb group; Bmi1; Neural stem cells; Integrins; Adhesion; Brain cancer
Transcriptional activation by GAGA factor is through its direct interaction with dmTAF3
Keywords: گروه پلی کامب; GAGA factor; GAF; Trithorax like; trithorax group; Polycomb group; BIP2; BTB/POZ domain; dTAFII155; dmTAF3;
DNMT1 interacts with the developmental transcriptional repressor HESX1
Keywords: گروه پلی کامب; aa; amino acid; DNMT1; DNA methyltransferase 1; SAFB1; scaffold attachment factor beta 1; RNF2; ring finger protein 2; Lonp2; lon peptidase 2, peroxisomal; ZFP592; zinc finger protein 592; BTBD2; BTB (POZ) domain containing 2; SRFBP1; serum response facto
ESC, ESCL and their roles in Polycomb Group mechanisms
Keywords: گروه پلی کامب; esc; escl; Polycomb Group; Hox genes; Histone H3; Lysine 27; Histone methyltransferase; Drosophila;
Epigenetic regulation of genes during development: A conserved theme from flies to mammals
Keywords: گروه پلی کامب; epigenetic; Hox cluster; chromatin; boundary; Polycomb group; tirthorax group; cellular memory
Genomic imprinting in plants: the epigenetic version of an Oedipus complex
Keywords: گروه پلی کامب; DAP; days after pollination; ddm1; decrease in dna methylation 1; DME; DEMETER; FIE; FERTLIZATION-INDEPENDENT ENDOSPERM; fis; fertilization-independent seed; mea; medea; met1; methyltransferase 1; PcG; Polycomb group; PHE1; PHERES 1; RT-PCR; reverse-trans
NSPc1, a mainly nuclear localized protein of novel PcG family members, has a transcription repression activity related to its PKC phosphorylation site at S183
Keywords: گروه پلی کامب; NSPc1; nervous system polycomb 1; PcG; polycomb group; COS-7; African green monkey cell line producing T antigen of SV40; HeLa; human cervical carcinoma cell line; SH-SY5Y; human neuroblastoma cell line; PCR; polymerase chain reaction; PKC; protein kinase
The PcG protein HPC2 inhibits RBP-J-mediated transcription by interacting with LIM protein KyoT2
Keywords: گروه پلی کامب; RBP-J; recombination signal-binding protein-Jk; NIC; intracellular domain of Notch; EBNA2; Epstein-Barr virus nuclear antigen 2; PcG; polycomb group; HDAC; histone deacetylase; cDNA; complementary DNA; RT-PCR; reverse transcription polymerase chain reac
The ESC-E(Z) complex participates in the hedgehog signaling pathway
Keywords: گروه پلی کامب; Cellular memory; Epigenetics; Polycomb group; Enhancer of zeste; Extra sex combs; Knock-down; Cyclopia; hedgehog signaling; Histone methylation; Medaka;
Tissue specificity of hedgehog repression by the Polycomb group during Drosophila melanogaster development
Keywords: گروه پلی کامب; Drosophila; hedgehog; engrailed; Polycomb group; antero-posterior identities;