Pharmacokinetics of single-dose oral pregabalin administration in normal dogs
Keywords: پرگابالین; analgesia; anticonvulsant; dog; oral; pharmacokinetics; pregabalin;
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The effects of pregabalin on sleep disturbance symptoms among individuals with fibromyalgia syndrome
Keywords: پرگابالین; Fibromyalgia syndrome; Pregabalin; Pain; Sleep disturbance; Insomnia; MOS Sleep Scale; Clinically important difference; Mediation analysis
Liquid chromatography atmospheric pressure chemical ionization tandem mass spectrometry method for the quantification of pregabalin in human plasma
Keywords: پرگابالین; Pregabalin; Liquid chromatography–tandem mass spectrometry; Atmospheric pressure chemical ionization; Human plasma; Pharmacokinetic study
Selective inhibitory effects of pregabalin on peripheral C but not A-delta fibers mediated nociception in intact and spinalized rats
Keywords: پرگابالین; pregabalin; spinal nociceptive-specific neurons; nociception; pre-emptive analgesia; bee venom; ANOVA; analysis of variance; BV; bee venom; cRF; cutaneous receptive field; DH; dorsal horn; NS; nociceptive-specific; PGB; pregabalin; WDR; wide-dynamic range
Add-on treatment with pregabalin for partial seizures with or without generalisation: Pooled data analysis of four randomised placebo-controlled trials
Keywords: پرگابالین; Pregabalin; Antiepileptic drugs; Partial seizures; Add-on treatment; Pooled data analysis
The anti-epileptic drug lacosamide (Vimpat®) has anxiolytic property in rodents
Keywords: پرگابالین; Lacosamide; Pregabalin; Sodium valproate; Conditioned fear; Anxiety; Diazepam; Hypothermia; (Rat); (Mouse)
Strategies for Managing Fibromyalgia
Keywords: پرگابالین; Dopamine D3 receptor agonists; Fibromyalgia; Nonpharmacologic interventions; Opiates; Pregabalin; Serotonin 5-HT3 receptor antagonists
Treatment of fibromyalgia syndrome with gabapentin and pregabalin - A meta-analysis of randomized controlled trials
Keywords: پرگابالین; Fibromyalgia syndrome; Systematic review; Meta-analysis; Randomized controlled trial; Gabapentin; Pregabalin;
Chronic neuropathic pain management in spinal cord injury patients. What is the efficacy of pharmacological treatments with a general mode of administration? (oral, transdermal, intravenous)
Keywords: پرگابالین; Spinal cord injury pain; Neuropathic pain; Pregabalin; Gabapentin; Tricyclic antidepressants; Strong opioidsBlessé médullaire; Douleur neuropathique; Prégabaline; Gabapentine; Tricyclique; Opioïdes forts
Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions
Keywords: پرگابالین; antiepileptic drugs; brivaracetam; carabersat; carisbamate; DP-valproic acid; drug interactions; eslicarbazepine; fluorofelbamate; fosphenytoin; ganaxolone; lacosamide; losigamone; pharmacokinetics; pregabalin; remacemide; retigabine; rufinamide; safinami
La gabapentine et la prégabaline en anesthésie
Keywords: پرگابالین; Gabapentine; Prégabaline; Analgésie postopératoire; Gabapentin; Pregabalin; Postoperative analgesia;
Comparative antiallodynic activity of morphine, pregabalin and lidocaine in a rat model of neuropathic pain produced by one oxaliplatin injection
Keywords: پرگابالین; Rat; Antinociceptive; Lidocaine; Morphine; Pregabalin
Efficacy and tolerability of pregabalin in patients with difficult-to-treat epilepsy and intellectual disability
Keywords: پرگابالین; Epilepsy; Intellectual disability; Therapy; Pregabalin; Antiepileptic drug
Development and validation of a direct enantiomeric separation of pregabalin to support isolated perfused rat kidney studies
Keywords: پرگابالین; Pregabalin; HPLC/MS/MS; Chiral separation; Validation
Bodyweight gain under pregabalin therapy in epilepsy: Mitigation by counseling patients?
Keywords: پرگابالین; Pregabalin; Bodyweight gain; Patient counseling; Adverse effects; Epilepsy
Pregabalin as a Treatment for Painful Diabetic Peripheral Neuropathy: A Meta-Analysis
Keywords: پرگابالین; Pregabalin; Diabetes; Pain; Neuropathy; Meta-analysis; Analgesia;
Reduction of secondarily generalized tonic–clonic (SGTC) seizures with pregabalin
Keywords: پرگابالین; Pregabalin; Secondarily generalized tonic–clonic; Seizure reduction; Placebo-controlled study; Refractory partial epilepsy
Pregabalin in patients with central neuropathic pain: A randomized, double-blind, placebo-controlled trial of a flexible-dose regimen
Keywords: پرگابالین; Pregabalin; Central neuropathic pain; Quality of life;
Efficacy of pregabalin in depressive symptoms associated with generalized anxiety disorder: A pooled analysis of 6 studies
Keywords: پرگابالین; Pregabalin; Generalized anxiety disorder; GAD; Comorbid depressive symptoms; Efficacy
Efficacy and safety of pregabalin in patients with diabetic peripheral neuropathy or postherpetic neuralgia: Open-label, non-comparative, flexible-dose study
Keywords: پرگابالین; Patient global impression of change; Clinical global impression of change neuropathic pain; Diabetic peripheral neuropathy; Postherpetic neuralgia; Pregabalin;
Pregabalin for relief of neuropathic pain associated with diabetic neuropathy: A randomized, double-blind study
Keywords: پرگابالین; Diabetes; Neuropathic pain; Pregabalin; Quality of life; Sleep;
Pregabalin for Postherpetic Neuralgia: Placebo-Controlled Trial of Fixed and Flexible Dosing Regimens on Allodynia and Time to Onset of Pain Relief
Keywords: پرگابالین; Postherpetic neuralgia; PHN; pregabalin; allodynia; pain; time to onset
Fibromyalgia relapse evaluation and efficacy for durability of meaningful relief (FREEDOM): A 6-month, double-blind, placebo-controlled trial with pregabalin
Keywords: پرگابالین; Fibromyalgia; Pregabalin; Treatment
Brief post-stressor treatment with pregabalin in an animal model for PTSD: Short-term anxiolytic effects without long-term anxiogenic effect
Keywords: پرگابالین; Post-traumatic Stress Disorder; Animal model; Pregabalin; Extreme behavioral response; Minimal behavioral response; Early drug intervention; Secondary prevention
A 14-week, Randomized, Double-Blinded, Placebo-Controlled Monotherapy Trial of Pregabalin in Patients With Fibromyalgia
Keywords: پرگابالین; Pregabalin; fibromyalgia; randomized; controlled trial
Descending facilitation from the brainstem determines behavioural and neuronal hypersensitivity following nerve injury and efficacy of pregabalin
Keywords: پرگابالین; RVM; 5HT; Neuropathy; Pain; Pregabalin; Spinal cord;
Pregabalin as add-on therapy for refractory partial seizures in every day clinical practice
Keywords: پرگابالین; Refractory; Epilepsy; Pregabalin; Treatment; Antiepileptic drugs; Efficacy; Adverse effects
Alpha-2-Delta Ligands for Singultus (Hiccup) Treatment: Three Case Reports
Keywords: پرگابالین; Singultus; hiccup treatment; alpha-2-delta; gabapentin; pregabalin
Pregabalin Reduces Muscle and Cutaneous Hyperalgesia in Two Models of Chronic Muscle Pain in Rats
Keywords: پرگابالین; Pregabalin; hyperalgesia; pain; carrageenan; acid
Utilidad de la pregabalina en el tratamiento de la neuropatÃa diabética dolorosa
Keywords: پرگابالین; Pregabalina; NeuropatÃa diabética; Dolor neuropático; Pregabalin; Diabetic neuropathy; Neuropathic pain;
Postoperative pain—clinical implications of basic research
Keywords: پرگابالین; central sensitization; gabapentin; hyperalgesia; peripheral sensitization; pregabalin; pre-emptive analgesia
Pregabalin, S-(+)-3-isobutylgaba, activates the descending noradrenergic system to alleviate neuropathic pain in the mouse partial sciatic nerve ligation model
Keywords: پرگابالین; Pregabalin; Neuropathic pain; Descending noradrenergic pain inhibitory system; NA turnover; α2-adrenergic receptors
Pharmacology and mechanism of action of pregabalin: The calcium channel α2–δ (alpha2–delta) subunit as a target for antiepileptic drug discovery
Keywords: پرگابالین; Anticonvulsant; Alpha2–delta; Calcium channel; Glutamate; Pregabalin; Gabapentin
Novel anticonvulsant drugs
Keywords: پرگابالین; AED; antiepileptic drug; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; CBZ; carbamazepine; DMCM; methyl-6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate; fPHT; free PHT (not bound to protein); GABA; γ-aminobutyric acid; GBP; gabapentin; G
Erectile dysfunction associated with pregabalin add-on treatment in patients with partial seizures: Five case reports
Keywords: پرگابالین; Pregabalin; Epilepsy; Erectile dysfunction; Side effect
Carboxylate bioisosteres of pregabalin
Keywords: پرگابالین; Gabapentin; Pregabalin; α2–δ Subunit; Tetrazole
α2δ and the mechanism of action of gabapentin in the treatment of pain
Keywords: پرگابالین; α2δ, calcium channel subunit; GABA, γ-aminobutyric acid gamma; GAT1, GABA transporter; DRG, dorsal root gangliaReview; Gabapentin; Pregabalin; Neurontin; Lyrica; Voltage gated calcium channel; Review; Pain
Pregabalin: A new antiepileptic drug for refractory epilepsy
Keywords: پرگابالین; Pregabalin; Anti epileptic drugs; Epilepsy
Pregabalin: From molecule to medicine
Keywords: پرگابالین; Generalized anxiety disorder; Pregabalin; Treatment; Mechanism of action; Alpha-2-delta; Clinical trials
Further potential of the GABA receptor in the treatment of insomnia
Keywords: پرگابالین; GABA; Hypnotic; THIP; Tiagabine; Pregabalin
(l)-Phenylglycine, but not necessarily other α2δ subunit voltage-gated calcium channel ligands, attenuates neuropathic pain in rats
Keywords: پرگابالین; Gabapentin; Pregabalin; Phenylglycine; Allodynia; Analgesia; Brain; Spinal nerve ligation
Neuropsychological and psychiatric impact of add-on titration of pregabalin versus levetiracetam: A comparative short-term study
Keywords: پرگابالین; Pregabalin; Levetiracteam; Add-on; Titration; Tolerability
Activity profile of pregabalin in rodent models of epilepsy and ataxia
Keywords: پرگابالین; Epilepsy; Antiepileptic drugs; Animal models; Pregabalin; Lyrica; (S)-(aminomethyl)-5-methylhexanoic acid
Relief of painful diabetic peripheral neuropathy with pregabalin: A randomized, placebo-controlled trial
Keywords: پرگابالین; Pregabalin; neuropathic pain; diabetic neuropathy;
Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomised, double-blind, multicentre, placebo-controlled trial of flexible- and fixed-dose regimens
Keywords: پرگابالین; Diabetic neuropathy; Dosing; Neuropathic pain; Postherpetic neuralgia; Pregabalin; Sleep;
Pregabalin in neuropathic pain: A more “pharmaceutically elegant” gabapentin?
Keywords: پرگابالین; pregabalin; gabapentin; neuropathic pain; postherpetic neuralgia; diabetic neuropathy;