Keywords: لوسمی Promyelocytic; AMPK; AMP-activated protein kinase; ARF6; ADP-ribosylation factor 6; AKT; protein kinase B; BBB; blood brain barrier; bFGF; b-fibroblast growth factors; b-FGFR; b-fibroblast growth factors receptor; ccRCC; clear cell renal cell carcinoma; ECs; endothelial
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Target ROS to induce apoptosis and cell cycle arrest by 5,7-dimethoxy-1,4-naphthoquinone derivative
Keywords: لوسمی Promyelocytic; 1,4-Naphthoquinone; Anticancer agent; Promyelocytic leukemia; Apoptosis;
Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity
Keywords: لوسمی Promyelocytic; ALT; Alternative lengthening of telomeres; APBs; ALT-associated PML bodies; BIR; Break-induced replication; CO-FISH; Chromosome orientation fluorescence in situ hybridization; DDR; DNA damage response; DOX; Doxycycline; DSBs; Double-strand breaks; HR; Hom
YAP promotes breast cancer metastasis by repressing growth differentiation factor-15
Keywords: لوسمی Promyelocytic; ALPP; alkaline phosphatase; AREG; amphiregulin; α-SMA; alpha smooth muscle actin; BIRC5; baculoviral inhibitor of apoptosis repeat-containing 5; ChIP; chromatin immunoprecipitation; CTGF; connective tissue growth factor; DDIT4; DNA-damage inducible trans
The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells
Keywords: لوسمی Promyelocytic; ALT; alternative lengthening of telomeres; CST; the CTC1/STN1/TEN1 trimeric complex; APBs; ALT-associated promyelocytic leukemia bodies; PML; promyelocytic leukemia; ECTR; extrachromosomal circular telomere repeats; TC; t-circle; CC; C-circle; HDR; homolo
ReviewThe Histone Variant H3.3 in Transcriptional Regulation and Human Disease
Keywords: لوسمی Promyelocytic; PTM; post-translational modification; DAXX; death domain-associated protein; UBN1; ubinuclein-1; HIRA; histone cell cycle regulation defective homolog A; ESC; embryonic stem cell; PML; promyelocytic leukemia; CHD1; chromodomain helicase DNA-binding domain
HDAC9 regulates the alternative lengthening of telomere (ALT) pathway via the formation of ALT-associated PML bodies
Keywords: لوسمی Promyelocytic; Cancer biology; Histone deacetylase (HDAC); Telomere; Alternative lengthening of telomere (ALT); Histone deacetylase 9 (HDAC9); Promyelocytic leukemia (PML); ALT; alternative lengthening of telomere; APB; ALT-associated promyelocytic leukemia nuclear body
Intracellular Ca2+ signaling and Ca2+ microdomains in the control of cell survival, apoptosis and autophagy
Keywords: لوسمی Promyelocytic; Apoptosis; Autophagy; Endoplasmic reticulum; IP3 receptor; Lysosomes; Mitochondria; AMBRA1; autophagy/Beclin 1 regulator 1; AMPK; AMP-activated kinase; ATF4; activating transcription factor-4; Atg; autophagy-related; BIRD-2; Bcl-2/IP3R disruptor-2; CREB;
Estrogen receptor alpha transcriptionally activates casein kinase 2 alpha: A pivotal regulator of promyelocytic leukaemia protein (PML) and AKT in oncogenesis
Keywords: لوسمی Promyelocytic; CK2; Casein Kinase 2; PML; Promyelocytic Leukemia; TBCA; (E)-3-(2,3,4,5-Tetrabromophenyl) acrylic acid; qRT-PCR; quantitative real time polymerase chain reaction; WCL; Whole cell lysate; SDS-PAGE; Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis
An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy
Keywords: لوسمی Promyelocytic; AA; Ascorbic acid; AEM1; ARE expression modulator 1; AEG1; Astrocyte elevated gene-1; Akt; Protein kinase B; AMPK; AMP-activated protein kinase; APL; Acute promyelocytic leukemia; ARE; Antioxidant response element; ATO; Arsenic trioxide; Bach; BTB and CNC
Downregulation of PEA-15 reverses G1 arrest, and nuclear and chromatin changes of senescence phenotype via pErk1/2 translocation to nuclei
Keywords: لوسمی Promyelocytic; HDF; human diploid fibroblasts; TPA; 12-O-tetradecanoylphorbol-13-acetate; SA-pErk1/2; senescence associated phospho-extracellular signal-regulated protein kinase 1/2; BrdU; 5-bromo-2â²-deoxyuridine; PML; promyelocytic leukemia; 53BP1; p53-binding protei
Silencing Daxx increases the anti-tumor activity of a TRAIL/shRNA Bcl-xL-expressing oncolytic adenovirus through enhanced viral replication and cellular arrest
Keywords: لوسمی Promyelocytic; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; Daxx; death domain-associated protein; STAT; signal transducer and activator of transcription; PI; propidium iodide; FACS; fluorescence-activated cell sorter; MTS; 3-(4,5-dimethylthiazol-2-yl
Study of PTEN subcellular localization
Keywords: لوسمی Promyelocytic; AKAP; A kinase anchoring protein; ArA; arachidonic acid; Ca2+; calcium; CLS; cytoplasmic localization signal; Co-IP; co-immunoprecipitation; COX; cytochrome c oxidase; ER; endoplasmic reticulum; ER-RFP; endoplasmic reticulum-targeted red fluorescent prote
Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing
Keywords: لوسمی Promyelocytic; AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-
The conserved sumoylation consensus site in TRIM5α modulates its immune activation functions
Keywords: لوسمی Promyelocytic; CA; capsid; HEK; human embryonic kidney; HTLV; human T-cell leukemia virus; IF; immunofluorescence; IP; immunoprecipitation; LMB; leptomycin B; MOI; multiplicity of infection; NB; nuclear body; PBS; phosphate buffer saline; PML; promyelocytic leukemia; SU
Dequalinium induces cytotoxicity in human leukemia NB4 cells by downregulation of Raf/MEK/ERK and PI3K/Akt signaling pathways and potentiation of specific inhibitors of these pathways
Keywords: لوسمی Promyelocytic; APL; acute promyelocytic leukemia; ATO; arsenic trioxide; ATRA; all-trans retinoic acid; DQA; dequalinium; GSH; glutathione; NB4; human acute promyelocytic leukemia derived cell line; PML; promyelocytic leukemia; ROS; reactive oxygen species; Dequalinium;
PML tumour suppression and beyond: Therapeutic implications
Keywords: لوسمی Promyelocytic; Promyelocytic leukemia; Promyelocytic leukemia protein; PML nuclear bodies; Isoform; Tumour suppression;
Regular ArticleThrombomodulin alfa treatment in patients with acute promyelocytic leukemia and disseminated intravascular coagulation: A retrospective analysis of an open-label, multicenter, post-marketing surveillance study cohort
Keywords: لوسمی Promyelocytic; APL; acute promyelocytic leukemia; AML; acute myelogenous leukemia; PML; promyelocytic leukemia; RARα; retinoic acid receptor-α; DIC; disseminated intravascular coagulation; ATRA; all-trans retinoic acid; ED; early death; TM; thrombomodulin; JALSG; Japa
Loss of DAXX and ATRX Are Associated With Chromosome Instability and Reduced Survival of Patients With Pancreatic Neuroendocrine Tumors
Keywords: لوسمی Promyelocytic; Pancreas; Neoplasm ALT; Prognosis; Human; ALT; alternative lengthening telomeres; ATRX; ATR-X gene; CGH; comparative genomic hybridization; CI; confidence interval; CIN; chromosomal instability; DAXX; death domain-associated protein gene; Exp(B); odds r
NFAT as cancer target: Mission possible?
Keywords: لوسمی Promyelocytic; ADP; adenosine di-phosphate; AICD; activation-induced cell death; AKAP79; A-kinase anchor protein 79; Ang-2; angiopoietin-2; AP1; activator protein 1; ARRE-2; antigen receptor response element-2; BMP4; bone morphogenetic protein 4; CABIN1; calcineurin-bin
PDT-induced epigenetic changes in the mouse cerebral cortex: A protein microarray study
Keywords: لوسمی Promyelocytic; ALA; aminolevulinic acid; AP-1/c-Jun; activation protein transcription factor 1; BACH1; breast cancer type1 protein; CENP-E; centromere protein E; hBrm/hsnf2a; chromatin remodeling factor; E2F4; E2F transcription factor 4; FOXC2; forkhead box C2; G9a; his
Histone deacetylase inhibitor (HDACI) mechanisms of action: Emerging insights
Keywords: لوسمی Promyelocytic; HDAC inhibitor; DNA damage response; DNA repair; Cell cycle checkpoints; Apoptosis; Rational combinations; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; APAF-1; apoptotic protease activating factor 1; ASK1; apoptosis signal-regulating ki
Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate
Keywords: لوسمی Promyelocytic; AML; acute myeloid leukemia; RTP; ribavirin triphosphate; mTOR; mammalian target of rapamycin; CD; circular dichroism; m7G; 7-methyl-guanosine; m7GTP; 7-methyl-guanosine-5â²-triphosphate; HSQC; heteronuclear single quantum coherence; RING; really interes
Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence
Keywords: لوسمی Promyelocytic; OIS; oncogene-induced senescence; MEF; mouse embryonic fibroblast; ERK; extracellular signal-regulated kinase; MEK; mitogen-activated protein kinase kinase; PI3K; phosphatidylinositol 3-kinase; pRb; retinoblastoma tumor suppressor protein; SA-β-Gal; sene
Effects of arsenic on modification of promyelocytic leukemia (PML): PML responds to low levels of arsenite
Keywords: لوسمی Promyelocytic; Arsenic; Promyelocytic leukemia; SUMO; Western blot; Oxidative stress; ICP-MS;
Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress
Keywords: لوسمی Promyelocytic; a.a.; amino acid; ATF; activating transcription factor; Bcl-2; B-cell lymphoma 2; Bcl-Xl; B-cell lymphoma-extra large; BH3; Bcl-2 homology 3; BI-1; Bax inhibitor-1; BiP; immunoglobulin heavy chain-binding protein; CHOP; C/EBP-homologous protein; CSQ; cals
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death
Keywords: لوسمی Promyelocytic; PD; Parkinson disease; DAergic; dopaminergic; DA; dopamine; 6-OHDA; 6-hydroxydopamine; ROS; reactive oxygen species; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â²,7â²-dichlorodihydrofluorescein diacetate acetyl ester; PML; promyelocytic leukemia; NAC; N-acetyl
Nuclear body formation and PML body remodeling by the human cytomegalovirus protein UL35
Keywords: لوسمی Promyelocytic; CMV; Cytomegalovirus; PML; Promyelocytic leukemia; pp71; UL35; UL35a; Nuclear bodies;
KN-62 analogues as potent differentiating agents of HL-60 cells
Keywords: لوسمی Promyelocytic; Promyelocytic leukemia; Calmodulin-dependent protein kinases; KN-62; HL-60 cells; Differentiating agents
αII-Spectrin interacts with five groups of functionally important proteins in the nucleus
Keywords: لوسمی Promyelocytic; Nonerythroid α-spectrin; Structural proteins; Fanconi anemia proteins; DNA repair proteins; Chromatin remodeling proteins; Transcription and RNA processing proteins; αSpIIΣâ; nonerythroid α-spectrin; PML; promyelocytic leukemia; FA; Fanconi anemia;
Isoforms of the promyelocytic leukemia protein differ in their effects on ND10 organization
Keywords: لوسمی Promyelocytic; PML; Promyelocytic leukemia; ND10; Nuclear organization;
Gene-inducing program of human dendritic cells in response to BCG cell-wall skeleton (CWS), which reflects adjuvancy required for tumor immunotherapy
Keywords: لوسمی Promyelocytic; ADA; adenosine deaminase; ANOVA; analysis of variance; AP-1; activating protein-1; BCG-CWS; bacillus Calmette-Guérin cell-wall skeleton; BIGM103; BCG-induced gene in monocyte, clone 103; CCL; chemokine (C-C motif) ligand; CD; cluster of differentiation;
Chromosome instability in neoplasia: chaotic roots to continuous growth
Keywords: لوسمی Promyelocytic; ALT; alternative telomere maintenance pathways; APC; anaphase-promoting complex; ATM; ataxia telangiectasia mutated; BFB; breakage-fusion-bridge (cycles); CIN; chromosomal instability in neoplasia; CGH; comparative genomic hybridization; FISH; fluores