دانلود مقالات ISI درباره پروتئین بانک اطلاعاتی + ترجمه فارسی

Piceatannol, a natural trans-stilbene compound, inhibits human glyoxalase I

Keywords: پروتئین بانک اطلاعاتی; Glyoxalase I; Inhibitor; Stilbenes; Piceatannol; Anticancer; GLO I; Glyoxalase I; BBGC; S-p-bromobenzylglutathione cyclopentyl diester; GSH; glutathione; HIPC-GSH; S-(N-hydroxy-N-indophenylcarbamoyl) glutathione; NSCLC; Non-small cell lung cancer; PDB; Pr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Microfluidic-based G-quadruplex ligand displacement assay for alkaloid anticancer drug screening

Keywords: پروتئین بانک اطلاعاتی; G4; G-quadruplex; CD; circular dichroism; CL; chemiluminescence; MD; molecular dynamics; SAU; sanguinarine; BER; berberine; CHE; chelerythrine; MAT; matrine; LIG; ligustrazine; PMT; photomultiplier tube; PME; Particle mesh Ewald method; GAFF; general AMBE

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Structural and biochemical characterization of FabK from Thermotoga maritima

Keywords: پروتئین بانک اطلاعاتی; FabK; Enoyl-acyl carrier protein (ACP) reductase; Crystal structure; Biochemical characterization; FabK; Enoyl-ACP reductase II; ENR; Enoyl-ACP reductase; FMN; Flavin mononucleotide; NADP; Nicotinamide adenine dinucleotide phosphate; PDB; Protein Data Ban

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Crystal structure of LysK, an enzyme catalyzing the last step of lysine biosynthesis in Thermus thermophilus, in complex with lysine: Insight into the mechanism for recognition of the amino-group carrier protein, LysW

Keywords: پروتئین بانک اطلاعاتی; M20 metallopeptidase; LysK; Amino-group carrier protein; Crystal structure; Thermus thermophilus; AAA; α-aminoadipate; PDB; Protein Data Bank; r.m.s.d.; root mean square deviation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Regression model for predicting pathogenic properties of SOD1 mutants based on the analysis of conformational stability and conservation of hydrogen bonds

Keywords: پروتئین بانک اطلاعاتی; ALS; amyotrophic lateral sclerosis; EN; elastic-network models; MD; molecular-dynamics simulations; PDB; protein data bank; WT; wild-type; ALS; SOD1; Elastic network models; Hydrogen bonds; Protein stability; Regression model; Patient survival time;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complex

Keywords: پروتئین بانک اطلاعاتی; HIF2α; hypoxia-inducible factor 2α; VHL; Von Hippel-Lindau; pVHL; von Hippel Lindau tumor suppressor protein; CODD; C-terminal oxygen-dependent degradation domain; 3D; three-dimensional; ARNT; aryl hydrocarbon receptor nuclear translocator; HRE; hypox

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of amino acids in antigen-binding site of class II HLA proteins independently associated with hepatitis B vaccine response

Keywords: پروتئین بانک اطلاعاتی; HBV; hepatitis B virus; anti-HBs; antibody to hepatitis B surface antigen; HBsAg; hepatitis B surface antigen; LD; linkage disequilibrium; PDB; Protein Data Bank; Leu26; leucine at position 26; GGPM; glycine-glycine-proline-methionine; DEAV; aspartic acid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis, and structure-activity relationships of pyrimido[4,5-b]indole-4-amines as microtubule depolymerizing agents that are effective against multidrug resistant cells

Keywords: پروتئین بانک اطلاعاتی; NCI; National Cancer Institute; MTAs; microtubule targeting agents; CA-4; combretastatin A-4; DMSO; dimethyl sulfoxide; PDB; Protein Data Bank; Pgp; P-glycoprotein; Rr; relative resistance; NMR; nuclear magnetic resonance; Microtubules; Pyrimido[4,5-b]ind

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

SCOPe: Manual Curation and Artifact Removal in the Structural Classification of Proteins - extended Database

Keywords: پروتئین بانک اطلاعاتی; SCOPe; Structural Classification of Proteins-extended; SCOP; Structural Classification of Proteins; PDB; Protein Data Bank; CPE; Clostridium perfringens enterotoxin; APA; Anthrax Protective Antigen; structure classification; protein evolution; database;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Compound heterozygous KCNQ1 mutations (A300T/P535T) in a child with sudden unexplained death: Insights into possible molecular mechanisms based on protein modeling

Keywords: پروتئین بانک اطلاعاتی; aa; amino acid; BWA; Burrows-Wheeler aligner; CaM; calmodulin; CPR; cardiopulmonary resuscitation; DNA; deoxyribonucleic acid; ECG; electrocardiogram; GOF; gain of function; KCNE1; potassium voltage-gated channel subfamily E member 1; Kv7.1; voltage-gated

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Genome-wide identification, cloning and characterization of SNARE genes in bread wheat (Triticum aestivum L.) and their response to leaf rust

Keywords: پروتئین بانک اطلاعاتی; SNARE; soluble N-ethylmaleimide sensitive factor adaptor protein; Receptors TMD; Trans-membrane domain; PR; Pathogenesis-related; qRT-PCR; quantitative Real Time PCR; CDD; Conserved Domain Database; HMM; Hidden Markov Model; MSA; Multiple sequence alignme

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Databases/Web ServersabYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction

Keywords: پروتئین بانک اطلاعاتی; CDR; complementarity-determining region; PDB; Protein Data Bank; IMGT; Immunogenetics Database; EMBL-ENA; European Molecular Biology Laboratory European Nucleotide Archive; antibodies; bioinformatics and computational biology; databases; sequence analysis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in the human Quinone Oxidoreductase 1 (NQO1)

Keywords: پروتئین بانک اطلاعاتی; SNP; Single nucleotide polymorphisms; nsSNPs; Non-synonymous SNPs; NQO1; NAD(P)H Quinone Oxidoreductase 1; SIFT; Sorting Intolerant from Tolerant; PolyPhen; phenotype polymorphism; ROVEAN; Protein Variation Effect Analyzer; PDB; Protein Data Bank; GDT; gl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Structural insight into mode of binding of Meropenem to CTX-M-15 type β-lactamase

Keywords: پروتئین بانک اطلاعاتی; PBPs; penicillin binding proteins; IPTG; isopropyl-β-d-1-thiogalactopyranoside; PDB; protein data bank; RFI; relative fluorescence intensity; CD; circular dichroism; Antibiotic resistance; Beta-lactamase; Meropenem; Fluorescence quenching; Molecular dock

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research ArticlePharmacophore based 3D-QSAR modeling, virtual screening and docking for identification of potential inhibitors of β-secretase

Keywords: پروتئین بانک اطلاعاتی; BACE1; β-secretase; AD; Alzheimer's disease; Aβ; amyloid-β; BBB; blood brain barrier; PDB; protein data bank; rmsd; root mean square deviation; IC50; inhibitory concentration; β-secretase; Alzheimer's disease; Pharmacophore; Virtual screening; Doc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors

Keywords: پروتئین بانک اطلاعاتی; Acetylcholinesterase inhibitor; Alzheimer's disease; Antarctic sponges; Discorhabdins; Molecular docking; Sponge metabolites; AChE; acetylcholinesterase; BChE; butyrylcholinesterase; eeAChE; electric eel acetylcholinesterase; ESI-MS; electrospray ionisati

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Databases/Web Servers3D-NuS: A Web Server for Automated Modeling and Visualization of Non-Canonical 3-Dimensional Nucleic Acid Structures

Keywords: پروتئین بانک اطلاعاتی; 3D; three-dimensional; PDB; Protein Data Bank; SD; Standard deviation; nucleic acids duplex; triplex; quadruplex; chimera; hairpin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Structural Insights into BAF47 and BAF155 Complex Formation

Keywords: پروتئین بانک اطلاعاتی; ESC; embryonic stem cell; RPT1; Repeat 1; ITC; isothermal titration calorimetry; GST; glutathione S-transferase; PDB; Protein Data Bank; NMR; nuclear magnetic resonance; HSQC; heteronuclear single quantum coherence; dsDNA; double-stranded DNA; BAF47; BAF1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2

Keywords: پروتئین بانک اطلاعاتی; IL; interleukin; Th2; T helper type 2; PDB; Protein Data Bank; VH; variable heavy; VL; variable light region; CDR; complementary-determining region; FW; framework; PBS; phosphate-buffered saline; HPLC-SEC; high-performance liquid chromatography-size-exc

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Importance of 5/6-aryl substitution on the pharmacological profile of 4ʹ-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1ʹ-biphenyl]-2-carboxylic acid derived PPARγ agonists

Keywords: پروتئین بانک اطلاعاتی; Peroxisome proliferator-activated receptor γ; Pharmacological profile; Coactivator recruitment; Transactivation assay; Molecular modeling; H; helix; LBD; ligand binding domain; PDB; Protein Data Bank; PPAR; peroxisome proliferator-activated receptor; PPR

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Mycobacterium tuberculosis chorismate mutase: A potential target for TB

Keywords: پروتئین بانک اطلاعاتی; Tuberculosis; Mycobacterium tuberculosis; Chorismate mutase; Inhibitors; BsCM; Bacillus subtilis chorismate mutase; CM; chorismate mutase; DAHP; 3-deoxy-d-arabinoheptulosonate 7-phosphate; EcCM; Escherichia coli chorismate mutase; HIV/AIDS; human Immunode

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Pyrrolizines: Design, synthesis, anticancer evaluation and investigation of the potential mechanism of action

Keywords: پروتئین بانک اطلاعاتی; ALK1; activin receptor-like kinase; CDCl3; deuterated chloroform; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; DSV; discovery studio visualizer; DYRK3; dual specificity tyrosine phosphorylation-regulated kinase; CDK2; cyclin-depende

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Keywords: پروتئین بانک اطلاعاتی; ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

MODCSA-CA: A multi objective diversity controlled self adaptive cuckoo algorithm for protein structure prediction

Keywords: پروتئین بانک اطلاعاتی; MODCSA; multi objective diversity controlled self adaptive; CA; cuckoo algorithm; CS; cuckoo search; PDB; Protein Data Bank; IMMALG; Immune Algorithm; I-PAES; inspired Pareto archived evolutionary strategy; HGA; Hybrid Genetic Algorithm; MODE-P; multi-obj

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters

Keywords: پروتئین بانک اطلاعاتی; membrane transport; major facilitator superfamily; alternating access; GLUT1; SLC2A; MP; membrane protein; PDB; Protein Data Bank; cryo-EM; electron cryomicroscopy; MFS; major facilitator superfamily; SLC; solute carrier; TM; transmembrane; SP; sugar port

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors

Keywords: پروتئین بانک اطلاعاتی; Tankyrase inhibitors; PARP family; Wnt/β-catenin signaling pathway; Wnt pathway disruption; Wnt-driven cancers; APC; adenomatous polyposis coli gene product; ARTD; ADP-ribosyltransferases; CK1; casein kinase 1; DMPK; drug metabolism and pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Rubredoxins derivatives: Simple sulphur-rich coordination metal sites and its relevance for biology and chemistry

Keywords: پروتئین بانک اطلاعاتی; Rd; rubredoxin; Dx; Desulforedoxin; Cp.; Clostridium pasturium; Dg.; Desulfovibrio gigas; Dd.; Desulfovibrio desulfuricans; Dv.; Desulfovibrio vulgaris; Pf.; Pyrococcus furiosus; X; amino acid residue; WT; wild type; ZFs; Zinc fingers; MT; metallothionein

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Unique binding mode of Evogliptin with human dipeptidyl peptidase IV

Keywords: پروتئین بانک اطلاعاتی; Dipeptidyl peptidase IV; DPP4; Evogliptin; Diabetes; Inhibitor; Complex structure; DPP4; dipeptidyl peptidase-IV; GLP-1; glucagon-like peptide-1; PDB; protein data bank; RMSD; root-mean-square deviation;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity

Keywords: پروتئین بانک اطلاعاتی; TTK; threonine tyrosine kinase; SAC; spindle assembly checkpoint; TNBC; triple-negative breast cancer; SPR; surface plasmon resonance; PDB; Protein Data Bank; PEG; polyethylene glycol; DMSO; dimethylsulfoxide; ATCC; American Type Culture Collection; targe

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular dynamics simulations of Zika virus NS3 helicase: Insights into RNA binding site activity

Keywords: پروتئین بانک اطلاعاتی; Zika virus; Flavivirus; NS3 helicase; Molecular dynamics; FTMap; Drug discovery; ZIKV; Zika virus; NS; non-structural; NS3h; NS3 helicase; PrM; membrane precursor; MD; molecular dynamics; RMSF; root mean square fluctuation; PDB; protein data bank; VMD; Vi

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Na+/K+-ATPase interaction with methylglyoxal as reactive metabolic side product

Keywords: پروتئین بانک اطلاعاتی; aa residue; amino acid residue; AMG; aminoguanidine, also pimagedine; Arg (R); arginine; ATP; adenosine triphosphate; BSA; bovine serum albumin; CHER; catalytic hydrogen evolution reaction; CML; Nε-(carboxymethyl)lysine; CPS; constant-current chronopoten

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

In silico identification of novel antagonists and binding insights by structural and functional analyses of guanylate kinase of Leishmania donovani and interaction with inhibitors

Keywords: پروتئین بانک اطلاعاتی; GK; guanylate kinase; VL; visceral leishmaniasis; GMPK; guanosine monophosphate kinase; 5GP; 5′-guanylic acid; GOLD; genetic optimization for ligand docking; CHARMM; chemistry of HARvard molecular mechanics; BLAST; basic local alignment search tool; PDB

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Exploring putative inhibitors of Death Associated Protein Kinase 1 (DAPK1) via targeting Gly-Glu-Leu (GEL) and Pro-Glu-Asn (PEN) substrate recognition motifs

Keywords: پروتئین بانک اطلاعاتی; DAPK1; Death Associated Protein Kinase 1; NMDARs; N-methyl-D-aspartate receptors; NMDAR2A or NR2A; N-methyl-D-aspartate receptor subtype 2A; NMDAR2B or NR2B; N-methyl-D-aspartate receptor subtype 2B; NSC; neuronal survival-signaling complex; NDC; neuronal

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Structure-function studies of BPP-BrachyNH2 and synthetic analogues thereof with Angiotensin I-Converting Enzyme

Keywords: پروتئین بانک اطلاعاتی; Docking; Molecular dynamics simulations; Molecular mechanics Poisson-Boltzmann surface area; g_mmpbsa; proline-Rich oligopeptide; Toxicological prediction; ACE; Angiotensin-I converting enzyme; ADT; AutoDock Tools; CC50; Mean cytotoxic concentration; IC50

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Iminoenamine based novel androgen receptor antagonist exhibited anti-prostate cancer activity in androgen independent prostate cancer cells through inhibition of AKT pathway

Keywords: پروتئین بانک اطلاعاتی; Prostate cancer; T877A; Androgen receptor antagonist; Bicalutamide; LNCaP; Apoptosis; AR; Androgen receptor; DHT; Dihydrotestosterone; AIPC; Androgen Independent Prostate Cancer; LBD; Ligand Binding Domain; R-BIC; R-Bicalutamide; ETS; Erythroblast Transfo

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-angiogenic potential of trypsin inhibitor purified from Cucumis melo seeds: Homology modeling and molecular docking perspective

Keywords: پروتئین بانک اطلاعاتی; BSA; bovine serum albumin; DMEM; Dulbecco's modified eagle's medium; BBI; Bowman-Birk inhibitor; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; HUVEC; human umbilical vein endothelial cells; LDH; lactate dehydrogenase; MTT; 3-(4,5-

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily

Keywords: پروتئین بانک اطلاعاتی; Tautomerase superfamily; 4-Oxalocrotonate tauomerase; cis-3-Chloroacrylic acid dehalogenase; 2-Oxo-3-pentynoate; Evolution; cis-CaaD; cis-3-chloroacrylic acid dehalogenase; CHES; N-Cyclohexyl-2-aminoethanesulfonic acid; DEAE; diethyl-aminoethyl; LB; Luria

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Structural analysis and insight into Zika virus NS5 mediated interferon inhibition

Keywords: پروتئین بانک اطلاعاتی; ZIKV; Zika virus; NS5; non-structural protein 5; SIAH2; seven in absentia homolog 2; STAT2; Signal Transducer and Activator of Transcription 2; MTase; methyltransferase; IFN; interferon; IRF9; Interferon Regulatory Factor 9; ISGF3; Interferon-Stimulated G

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular cloning of ESR2 and gene expression analysis of ESR1 and ESR2 in the pituitary gland of the Chinese alligator (Alligator sinensis) during female reproductive cycle

Keywords: پروتئین بانک اطلاعاتی; ESRs; estrogen receptors; ERα/ESR1; estrogen receptor alpha; ERβ/ ESR2; ESTROGEN receptor beta; cDNA; DNA complementary to RNA; mRNA; Messenger RNA; PCR; polymerase chain reaction; RT; reverse transcription; qPCR; quantitative real-time PCR; 3D; three d

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

The key residue within the second extracellular loop of human EP3 involved in selectively turning down PGE2- and retaining PGE1-mediated signaling in live cells

Keywords: پروتئین بانک اطلاعاتی; EP selectivity; G protein-coupled receptor (GPCR); Prostaglandin; Prostaglandin E1; Prostaglandin E2; Receptor regulation; AA; arachidonic acid; COX-1 and -2; cyclooxygenase-1 and -2, respectively; cPGES; cytosolic PGES; DGLA; dihomo-γ-linolenic acid; EP

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

In vivo effects of metal ions on conformation and mechanical performance of silkworm silks

Keywords: پروتئین بانک اطلاعاتی; ASG; anterior silk gland; CD; circular dichroism; CDS; coding sequence; EST; expressed sequence tag; FTIR; Fourier-transform infrared spectroscopy; ICP-AAS; inductively coupled plasma atomic absorption spectroscopy; MSG; middle silk gland; NCBI; National

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and evaluation of scutellarein-O-acetamidoalkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease

Keywords: پروتئین بانک اطلاعاتی; Alzheimer's disease; Scutellarein-O-acetamidoalkylbenzylamines; Multifunctional agents; Acetylcholinesterase inhibitors; Aβ aggregation inhibitors; Antioxidant agents; AD; Alzheimer's disease; AChE; acetylcholinesterase; ACh; acetylcholine; Aβ; β-amylo

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2017 سفارش ترجمه

Mechanisms of protection against irreversible oxidation of the catalytic cysteine of ALDH enzymes: Possible role of vicinal cysteines

Keywords: پروتئین بانک اطلاعاتی; Cysteine conformers; ALDHs catalytic loop; Catalytic Cys pKa; Sulfenic acid; Disulfide bond; Residue conservation; ALDH; aldehyde dehydrogenase; BME; 2-mercaptoethanol; DTT; 1,4-dithiothreitol; GSH; reduced glutathione; HsALDH2; mature human ALDH2; PDB; P

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Structure, function, and mechanism of proline utilization A (PutA)

Keywords: پروتئین بانک اطلاعاتی; Flavoprotein; Flavin-dependent reaction; Protein structure; proline catabolism; Multifunctional enzymes; Substrate channeling; Aldehyde dehydrogenase; Enzyme hysteresis; ALDH; aldehyde dehydrogenase; ALDHSF; aldehyde dehydrogenase superfamily; BbPutA; Bde

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

Keywords: پروتئین بانک اطلاعاتی; Phenyl [(phenylcarbamoyl)amino]benzene-1-sulfonate derivatives; N-Phenyl-[(phenylcarbamoyl)amino]benzene-1-sulfonamide derivatives; Fragment-linking strategy; Dengue virus; NS5 methyltransferase inhibitors; Antiviral activity; DENV; dengue virus; NS; non-

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

Production of a soluble single-chain variable fragment antibody against okadaic acid and exploration of its specific binding

Keywords: پروتئین بانک اطلاعاتی; Okadaic acid; CLEIA; Single-chain variable fragment; Binding complex; OA; okadaic acid; DSP; diarrhetic shellfish poisoning; ELISA; enzyme-linked immunosorbent assay; scFv; single-chain variable fragment; CDR; complementarity-determining region; PDB; Prot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Web-based volume slicer for 3D electron-microscopy data from EMDB

Keywords: پروتئین بانک اطلاعاتی; CSS; Cascading Style Sheets; DOM; Document Object Model; EMDB; Electron Microscopy Data Bank; EBI; European Bioinformatics Institute; NMR; Nuclear Magnetic Resonance; OME; Open Microscopy Environment; OMERO; OME Remote Objects; PDB; Protein Data Bank; PDB

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

The MPN domain of Caenorhabditis elegans UfSP modulates both substrate recognition and deufmylation activity

Keywords: پروتئین بانک اطلاعاتی; UfSP; Ufm1; MPN domain; Deufmylation; Crystal structure; Ufm1; Ubiquitin-fold modifier 1; UfSP; Ufm1 specific protease; cUfSP; UfSP from C. elegans; UBL; ubiquitin-like protein; ER; endoplasmic reticulum; MPN; Mpr1p and PAD1p N-terminal; UfBP1; Ufm1 bindi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Crystal structure of the enzyme-product complex reveals sugar ring distortion during catalysis by family 63 inverting α-glycosidase

Keywords: پروتئین بانک اطلاعاتی; EcYgjK; Escherichia coli YgjK; GH63; glycoside hydrolase family 63; Glc1,2Gal; 2-O-α-d-glucopyranosyl-d-galactose; β-GlcF; β-glucopyranosyl fluoride; PDB; Protein Data Bank; RMSD; root mean squared deviation; Glycoside hydrolase family 63; Inverting me

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The unusual substrate specificity of a virulence associated serine hydrolase from the highly toxic bacterium, Francisella tularensis

Keywords: پروتئین بانک اطلاعاتی; DSF; differential scanning fluorimetry; FTT0941c; virulence associated serine hydrolase from Francisella tularensis; HSL; hormone sensitive lipase; KEGG; Kyoto Encyclopedia of Genes and Genomes; LB; Luria-Bertani broth; MWCO; molecular weight cut-off; Ni-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه