دانلود مقالات ISI درباره پروتئین بانک اطلاعاتی + ترجمه فارسی

Establishment of a human indoleamine 2, 3-dioxygenase 2 (hIDO2) bioassay system and discovery of tryptanthrin derivatives as potent hIDO2 inhibitors

Keywords: پروتئین بانک اطلاعاتی; Indoleamine 2; 3-dioxygenase 2; IDO2 bioassay system; IDO2 inhibitor; Tryptanthrin derivatives; hIDO2; human indoleamine 2, 3-dioxygenase 2; IDO1; indoleamine 2, 3-dioxygenase 1; L-1-MT; L-1-methyl-tryptophan; TDO; tryptophan 2, 3-dioxygenase; LLC; Lewis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1

Keywords: پروتئین بانک اطلاعاتی; Arachidonic acid; Cyclooxygenase-2; Microsomal prostaglandin E2 synthase; Polyunsaturated fatty acid; Prostaglandin E2; 10aa; 10 amino acid residues; AA; arachidonic acid; CHD; coronary heart disease; COX-1 and -2, respectively; cyclooxygenase-1 and -2; c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Evaluation of in vitro and in vivo anti-inflammatory effects of (−)-pseudosemiglabrin, a major phytoconstituent isolated from Tephrosia apollinea (Delile) DC

Keywords: پروتئین بانک اطلاعاتی; ANOVA; Analysis Of Variance; COX; Cyclooxygenase; DMSO; Dimethyl Sulfoxide; ELISA; Enzyme-Linked Immunosorbent Assay; IgG; Immunoglobulin G; IFN-α, -γ; Interferon-alpha, gamma; IL-1; Interlukin-1; LPS; lipopolysaccharide; NO; nitric oxide; µ-OR; opioid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza

Keywords: پروتئین بانک اطلاعاتی; Influenza neuraminidase; Oseltamivir; Tamiphosphor; Isothermal titration calorimetry; Crystal structure; Lattice-translocation defect; 4-MUNANA; 2′-(4-methylumbelliferyl)-α-d-N-acetylneuraminic acid; NA; neuraminidase; PDB; protein data bank; ITC; isot

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Gypsy moth pheromone-binding protein-ligand interactions: pH profiles and simulations as tools for detecting polar interactions

Keywords: پروتئین بانک اطلاعاتی; Gypsy moth; Olfaction; Ligand interactions; Pheromone-binding protein; Homology modeling; pH profile of ligand binding; (−)-Dis; (−)-disparlure = (7S, 8R)-epoxy-2-methyloctadecane; (+)-Dis; (+)-disparlure = (7R, 8S)-epoxy-2-methyloctadecane; ANOVA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Lipases from the genus Rhizopus: Characteristics, expression, protein engineering and application

Keywords: پروتئین بانک اطلاعاتی; ROL; R. oryzae lipase; RCL; R. chinensis lipase; RSL; R. stolonifer lipase; RML; Rhizomucor miehei lipase; mROL; the mature R. oryzae lipase; ProROL; the R. oryzae prolipase; r28ROL; the mature R. oryzae lipase containing 28 amino acids of the prosequence

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Development and Characterization of FLT3-Specific Curcumin-Loaded Polymeric Micelles as a Drug Delivery System for Treating FLT3-Overexpressing Leukemic Cells

Keywords: پروتئین بانک اطلاعاتی; targeted drug delivery; micelle; peptides; polymeric drug delivery systems; nanoparticle; CM; curcumin; FLT3; Feline McDonough Sarcoma (FMS)-like tyrosine kinase 3; P407; poloxamer 407; PDB; protein data bank;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Adhesion GPCRs in immunology

Keywords: پروتئین بانک اطلاعاتی; GPCR; G protein-coupled receptor; aGPCR; adhesion G protein-coupled receptor; ADGR; general adhesion GPCR name followed by class and subtype specific code; 7TM; 7 transmembrane; VLGR1; very large G protein-coupled receptor 1; ECD; extracellular domain; GP

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Contribution of bacteriochlorophyll conformation to the distribution of site-energies in the FMO protein

Keywords: پروتئین بانک اطلاعاتی; AHC; agglomerative hierarchical clustering; BChl; bacteriochlorophyll; Chl; chlorophyll; E(BChl)cryst; in vacuo SPE of BChl in protein bound conformation; ΔQy[Mac]; site-energy perturbation due to macrocycle distortion; dip; mean absolute deviation of NS

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Comparative genomics study for identification of putative drug targets in Salmonella typhi Ty2

Keywords: پروتئین بانک اطلاعاتی; S. typhi; Salmonella typhi; KEGG; Kyoto Encyclopedia of Genes and Genomes; DEG; Database of Essential Genes; WHO; World Health Organization; PDB; Protein Data Bank; NCBI; National Center for Biotechnology Information; MDRTF; Multi-Drug Resistance Typhoid

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain

Keywords: پروتئین بانک اطلاعاتی; PDB; protein data bank; CHD; chromodomain helicase DNA-binding protein; ISWI; imitation switch; CHCT; CHD1 helical C-terminal domain; EMSA; electrophoretic mobility shift assay; PNK; polynucleotide kinase; HMM; hidden Markov model; NOE; nuclear Overhauser

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors

Keywords: پروتئین بانک اطلاعاتی; HGPRT; hypoxanthine-guanine phosphoribosyltransferase; HPRT; hypoxanthine phosphoribosyltransferase; APRT; adenosine phosphoribosyltransferase; XPRT; xanthine phosphoribosyltransferase; CL; cutaneous leishmaniasis; MCL; muco-cutaneous leishmaniasis; VL; v

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

The RNA 3D Motif Atlas: Computational methods for extraction, organization and evaluation of RNA motifs

Keywords: پروتئین بانک اطلاعاتی; HL; Hairpin Loop; IL; Internal Loop; 3WJ; 3-way Junction; 4WJ; 4-way Junction; MHJ; Multi-Helix Junction; 2D structure; Secondary structure; PDB; Protein Data Bank; NDB; Nucleic Acid Database; WC; Watson-Crick; non-WC; non-Watson-Crick; BP; basepair; NR;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Salmonella enterica serovar Typhimurium growth is inhibited by the concomitant binding of Zn(II) and a pyrrolyl-hydroxamate to ZnuA, the soluble component of the ZnuABC transporter

Keywords: پروتئین بانک اطلاعاتی; SeZnuA; Salmonella enterica ZnuA; RDS library; Roberto Di Santo library; PDB; Protein Data Bank; ZnuA; ZnuABC zinc transporter; Salmonella enterica; X-ray structure; Lead compounds;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

In-silico structural analysis of E509K mutation in LARGE and T192M mutation in Alpha Dystroglycan in the inhibition of glycosylation of Alpha Dystroglycan by LARGE

Keywords: پروتئین بانک اطلاعاتی; DMD; Duchenne Muscular Dystrophy; α-DG; Alpha Dystroglycan; DAPC; Dystrophin Associated Protein Complex; MDDGC9; Muscular Dystrophy Dystroglycanopathy type C9; OMIM; Online Mendelian Inheritance in Man; EC; Enzyme Commission number; MDDGB6; Muscular Dyst

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights

Keywords: پروتئین بانک اطلاعاتی; SDF-1; stromal cell-derived factor 1; GPCR; G protein-coupled receptor; CNS; central nervous system; NS; nervous system; DRG; dorsal root ganglion; OPC; oligodendrocyte precursor cell; MS; multiple sclerosis; PDB; Protein Data Bank; TM; transmembrane; EL;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Reversible oxidation controls the activity and oligomeric state of the mammalian phosphoglycolate phosphatase AUM

Keywords: پروتئین بانک اطلاعاتی; CD; circular dichroism; DTT; dithiothreitol; EGF; epidermal growth factor; G3P; glycerol-3-phosphate; HAD; haloacid dehalogenase; IAA; iodoacetic acid; IAP; iodoacetyl polyethylene glycol; LDH; lactate dehydrogenase; MALS; multi angle light scattering; PD

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Structural and biochemical characterization of bacterial YpgQ protein reveals a metal-dependent nucleotide pyrophosphohydrolase

Keywords: پروتئین بانک اطلاعاتی; HD; histidine-aspartate; (d)NTP; (deoxy)ribonucleoside triphosphate; bsYpgQ; Bacillus subtilis YpgQ; dNTP; deoxyribonucleoside triphosphate; NTP; ribonucleoside triphosphate; dNMP; deoxyribonucleoside monophosphate; Pi; inorganic monophosphate; PPi; inorg

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

All-atom molecular dynamics simulations of lung surfactant protein B: Structural features of SP-B promote lipid reorganization

Keywords: پروتئین بانک اطلاعاتی; SP-B; surfactant protein B; LS; lung surfactant; PC; phosphocholine; DPPC; 1,2-dipalmitoyl-sn-glycero-3-phosphocholine; PG; phosphatidylglycerol; POPC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; AA; all-atom; CG; coarse-grained; MD; molecular dynam

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Structural insight into activation of homoserine dehydrogenase from the archaeon Sulfolobus tokodaii via reduction

Keywords: پروتئین بانک اطلاعاتی; HSD; homoserine dehydrogenase; Tris; tris(hydroxymethyl)aminomethane; PDB; Protein Data Bank; Tricine; N-[tris(hydroxymethyl)methyl]glycine; Bis-tris; 2,2-bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol; HEPES; [4-(2-hydroxyethyl)-1-piperazinyl] ethanesu

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis, and biological evaluation of oxindole derivatives as antidepressive agents

Keywords: پروتئین بانک اطلاعاتی; MAO; monoamine oxidase; FAD; flavin-adenine dinucleotide; FST; forced swimming test; TST; tail suspension test; %DID; percentage decrease in immobility duration; PDB; protein data bank; Oxindole derivatives; Antidepressant activity; MAO-A inhibitors; Forc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Crystal structure of the C-terminal domain of tubulin-binding cofactor C from Leishmania major

Keywords: پروتئین بانک اطلاعاتی; ARL3; ADPribosylation factor-like protein 3; CARP; cyclase-associated proteins and X-linked retinitis pigmentosa 2 gene products; TEV; tobacco etch virus; TBC; tubulin-binding cofactor; LmTBCC; TBCC from Leishmania major; LmTBCC-C; C-terminal domain of th

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Evolving understanding of translocator protein 18 kDa (TSPO)

Keywords: پروتئین بانک اطلاعاتی; TSPO; translocator protein 18 kDa; PBR; peripheral-type benzodiazepine receptor; RsTSPO; TSPO from Rhodobacter sphaeroides; BcTSPO; TSPO from Bacillus cereus; mTSPO; TSPO from mouse; MPTP; mitochondrial permeability transition pore; VDAC; voltage depende

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Contribution to catalysis of ornithine binding residues in ornithine N5-monooxygenase

Keywords: پروتئین بانک اطلاعاتی; Flavin-dependent monooxygneases; Siderophore; Ornithine hydroxylase; Hydroperoxyflavin; SidA; ornithine N5-monooxygenase siderophore A; wtSidA; wild-type SidA; Orn; ornithine; MbtG; lysine N6-monoxygenase from Mycobacterium tuberculosis; PDB; protein data

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding

Keywords: پروتئین بانک اطلاعاتی; ECD; extracellular domain of P2X4 receptor; HD; head domain of P2X4 receptor; HSQC; heteronuclear single quantum coherence; ITC; isothermal titration calorimetry; MALDI-TOF-MS; matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Structural consequences of aglycosylated IgG Fc variants evolved for FcγRI binding

Keywords: پروتئین بانک اطلاعاتی; Fc; fragment crystallizable; IgG; immunoglobulin G; Fab; fragment antigen binding; FcγR; Fc gamma receptor; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; CDC; complement-dependent cytotoxicity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Investigations on the role of CH…O interactions and its impact on stability and specificity of penicillin binding proteins

Keywords: پروتئین بانک اطلاعاتی; HBAT; Hydrogen Bond Analysis Tool; HMM; high molecular mass penicillin binding proteins; LMM; low molecular mass penicillin binding proteins; PBPs; penicillin binding proteins; PDB; protein data bank; SASA; solvent accessible surface area; Gram positive b

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Structure and intrinsic disorder of the proteins of the Trypanosoma brucei editosome

Keywords: پروتئین بانک اطلاعاتی; gRNA; guide RNAs; RECC; RNA editing core complex; MQAPs; Model Quality Assessment Programs; GDT_TS; global distance test total score; PROQ; Protein Quality Predictor; RMSD; root-mean-square deviation; IDRs; intrinsically disordered regions; NTD; N-termina

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Wedelolactone induces growth of breast cancer cells by stimulation of estrogen receptor signalling

Keywords: پروتئین بانک اطلاعاتی; Breast cancer; Estrogen receptor; Phytoestrogen; Wedelolactone; AP-1; activator protein 1; CHFCS; charcoal stripped fetal bovine serum; CCND1; cyclin D1; CTSD; cathepsin D; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ECL; enhan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Crystal structure of family 4 uracil-DNA glycosylase from Sulfolobus tokodaii and a function of tyrosine 170 in DNA binding

Keywords: پروتئین بانک اطلاعاتی; BSA; bovine serum albumin; HEX; hexachloro-fluorescein; MES; 2-(N-morpholino)ethanesulfonic acid; MR; molecular replacement; PCNA; proliferating cell nuclear antigen; PDB; protein data bank; TLS; translation, liberation and screw; UDG; uracil-DNA glycos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes

Keywords: پروتئین بانک اطلاعاتی; Cytochrome P450; Structure-function relationship; Site-directed mutagenesis; Monooxygenase coupling; CYP; cytochrome P450; ITC; isothermal titration calorimetry; H/D; hydrogen deuterium; DXMS; H/D exchange coupled to mass spectrometry; SNP; single nucle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-osmotic and antioxidant activities of gigantol from Dendrobium aurantiacum var. denneanum against cataractogenesis in galactosemic rats

Keywords: پروتئین بانک اطلاعاتی; DC; diabetic cataracts; AR; aldose reductase; NO; nitric oxide; iNOS; inducible nitric oxide synthase; ARI; aldose reductase inhibitors; PBS; phosphate buffer saline; FBS; fetal bovine serum; NIH; National Institute of Health; MD; molecular docking; PDB;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The role of AGR2 and AGR3 in cancer: Similar but not identical

Keywords: پروتئین بانک اطلاعاتی; AGR2; AGR3; PDI family; Cancer; AA; amino acids; ALS; familial amyotrophic lateral sclerosis; AGR; anterior gradient; AhR; aryl hydrocarbon receptor; AR; androgen receptor; CAPN8; calpain 8; CAPN9; calpain 9; CDDP; cisplatin; CFTR; cystic fibrosis transme

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

A conserved tryptophan (W91) at the barrel-lid junction modulates the packing and stability of Kunitz (STI) family of inhibitors

Keywords: پروتئین بانک اطلاعاتی; WCI; winged bean chymotrypsin inhibitor; ETI; Erythrina caffra trypsin inhibitor; STI; soybean trypsin inhibitor; BPTI; bovine pancreatic trypsin inhibitor; ETIL-WCIS; chimera having loop of ETI on the scaffold of WCI; PDB; Protein Data Bank; SDM; site di

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Interactions of a potent cyclic peptide inhibitor with the light chain of botulinum neurotoxin A: Insights from X-ray crystallography

Keywords: پروتئین بانک اطلاعاتی; BoNT; botulinum neurotoxin; Balc; botulinum neurotoxin A light chain; Balc424; Balc truncated at residue 424; Balc448; full-length Balc; CPI-1; cyclic peptide inhibitor-1; CPI-2; cyclic peptide inhibitor-2; DAB; 2,4-diaminobutanoic acid; FRET; Förster re

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Structure and function of Mycobacterium smegmatis 7-keto-8-aminopelargonic acid (KAPA) synthase

Keywords: پروتئین بانک اطلاعاتی; KAPA; 7-keto-8-aminopelargonic acid; PLP; pyridoxal 5′-phosphate; ADS; albumin-dextrose-saline; TEV; tobacco etch virus; KAM; N-(7-keto-8-aminopelargonic acid)-(3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-yl-methane); PDB; Protein Data Bank; Mycob

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [18F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging

Keywords: پروتئین بانک اطلاعاتی; ACN; acetonitrile; AcOH; acetic acid; ADAM; a disintegrin and metalloproteinase; CD; catalytic domain; DCC; N,N′-dicyclohexylcarbodiimide; DCM; dichloromethane; DMF; N,N-dimethylformamide; ECM; extracellular matrix; EOB; end of bombardment; EOS; end of

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

A theoretical view of the C3d:CR2 binding controversy

Keywords: پروتئین بانک اطلاعاتی; C3d; complement fragment 3d; CR2; complement receptor 2; SCR; short consensus repeat; PDB; protein data bank; MD; molecular dynamics; SASA; solvent-accessible surface area; SMD; steered molecular dynamics; AESOP; analysis of electrostatic similarities of

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Towards the evaluation in an animal disease model: Fluorinated 17β-HSD1 inhibitors showing strong activity towards both the human and the rat enzyme

Keywords: پروتئین بانک اطلاعاتی; 17β-Hydroxysteroid dehydrogenase type 1; Interspecies differences; Estrogen-dependent diseases; Estrogen mimetics; Non-steroidal inhibitors; 17β-HSD1; 17β-hydroxysteroid dehydrogenase type 1; 17β-HSD2; 17β-hydroxysteroid dehydrogenase type 2; E1; est

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Multiple binding modes of a small molecule to human Keap1 revealed by X-ray crystallography and molecular dynamics simulation

Keywords: پروتئین بانک اطلاعاتی; DTT; dithiothreitol; Keap1; Kelch-like ECH-associated protein 1; MD; molecular dynamics; Nrf2; Nuclear factor erythroid 2-related factor 2; PDB; Protein Data Bank; Oxidative stress; Antioxidant response; β-Propeller; Crystal packing; Fragment-based drug

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms of DNA methyltransferase-inhibitor interactions: Procyanidin B2 shows new promise for therapeutic intervention of cancer

Keywords: پروتئین بانک اطلاعاتی; DNMT; DNA methyltransferases; EGCG; epigallocathechin-3-gallate; SAH; S-Adnosyl-l-homocysteine; ChEBI; chemical entities of biological interest; PDB; protein data bank; UniProt; the Universal Protein knowledgebase; CHARMm; chemistry at HARvard molecular m

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Homology modeling, functional annotation and comparative genomics of outer membrane protein H of Pasteurella multocida

Keywords: پروتئین بانک اطلاعاتی; 3D; Three dimensional; BLAST; Basic Local Alignment Search Tool; BLASTp; Protein-BLAST; CDD; Conserved Domains Database; Da; Dalton; DEG; Database of Essential Genes; GO; Gene Ontology; GRAVY; Grand Average of Hydropathy; KAAS; KEGG automatic annotation s

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85

Keywords: پروتئین بانک اطلاعاتی; CDR; complementarity determining region; Dmax; maximum particle distance; FBS; fetal bovine serum; GAM; goat anti-mouse; HABD; hyaluronate-binding domain; HSQC; heteronuclear single quantum coherence; I(0); forward scattering; IPTG; isopropyl β-d-1-thiog

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Bioinformatics analyses provide insight into distant homology of the Keap1-Nrf2 pathway

Keywords: پروتئین بانک اطلاعاتی; ADT; AutoDock Tools; ARE; antioxidant response element; BLAST; Basic Local Alignment Search Tool; DHSP; Distant Homology Search Pipeline; NTMT; NCBI Taxonomy Mapping Tool; HMM; Hidden Markov Model; HMMER3; HMM-based utility version 3; Keap1; Kelch-like EC

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: پروتئین بانک اطلاعاتی; AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

N-(1′-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia

Keywords: پروتئین بانک اطلاعاتی; Acylhydrazones; Colchicine; Tubulin; Microtubule assembly; Cell migration; Leukemia; Cancer; ABT-751; N-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide; CHNS; elemental analysis; DAMA-colchicine; N-deacetyl-N-(2-mercaptoacetyl)-colchici

دانلود رایگان متن کامل مقاله ISI 88 صفحه سال انتشار : 2015 سفارش ترجمه

Modifying the determinants of α-ketoacid substrate selectivity in mycobacterium tuberculosis α-isopropylmalate synthase

Keywords: پروتئین بانک اطلاعاتی; AcCoA; acetyl coenzyme A; HCS; homocitrate synthase; IPMS; α-isopropylmalate synthase; IPTG; isopropyl thio-d-galactoside; KIV; α-ketoisovalerate; PDB; protein data bank; MtuIPMS; Mycobacterium tuberculosis IPMS; TthHCS; Thermus thermophilus HCS; Leucin

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Crystal structure and biochemical studies of Brucella melitensis 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Keywords: پروتئین بانک اطلاعاتی; BmMTAN; Brucella melitensis MTAN; INT; 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride; MTA; 5′-methylthioadenosine; MTAN; MTA/SAH nucleosidase; NP-1; nucleoside phosphorylase-1; PDB; Protein Data Bank; PEG; polyethylene glycol; r.m.s.d.

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator

Keywords: پروتئین بانک اطلاعاتی; c-di-GMP; cyclic dimeric guanosine monophosphate; DGC; diguanylate cyclase; GTP; guanosine triphosphate; MorA; motility regulator A; PDB; protein data bank; PDE; phosphodiesterase; pGpG; phosphate guanosine phosphate guanosine; Motility regulator A; Digua

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Functional characterization of a novel missense mutation, His147Arg, in A1 domain of FV protein causing type II deficiency

Keywords: پروتئین بانک اطلاعاتی; FV; Congenital factor V; FVIII; coagulation FVIII; FX; coagulation factor X; MD; molecular dynamics; CP; ceruloplasmin; wt; wild-type; Asp; aspartic acid; His; histidine; Arg; arginine; Cys; cystein; PCR; polymerase chain reaction; PDB; protein data bank;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه