دانلود مقالات ISI درباره Prpsc + ترجمه فارسی

Enhancement of protein misfolding cyclic amplification by using concentrated cellular prion protein source

Keywords: Prion; Transmissible spongiform encephalopathy; PrPC; PrPSc; Protein misfolding cyclic amplification; Transgenic mice

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

α-cleavage of the prion protein occurs in a late compartment of the secretory pathway and is independent of lipid rafts

Keywords: ADAM; a disintegrin and metalloprotease; Endo H; Endoglycosidase H; ER; endoplasmic reticulum; GPI; glycosyl-phosphatidylinositol; PBS; phosphate-buffered saline; PNGase F; peptide N-glycosidase F; PrPC; cellular form of prion protein; PrPSc; infectious,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Utility of RNAi-mediated prnp gene silencing in neuroblastoma cells permanently infected by prions: Potentials and limitations

Keywords: Prion; PrPC; PrPSc; RNAi; siRNA; shRNA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Characterization of sheep (Ovis aries) palatine tonsil innervation

Keywords: fluorescent tracers; immunohistochemistry; sympathetic innervation; prion diseases; ANS; autonomic nervous system; CCG; cranial cervical ganglia; CGRP; calcitonin gene-related peptide; CNS; central nervous system; CT-FITC; cholera toxin subunit B; CTG; ce

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Immunolocalisation of PrPSc in scrapie-infected N2a mouse neuroblastoma cells by light and electron microscopy

Keywords: PrPSc; Electron microscopy; Immunofluorescence; Early endosomes; Late endosomes; Lysosomes; Clathrin-coated pits; Exosomes

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2009 سفارش ترجمه

Octapeptide repeat region of prion protein (PrP) is required at an early stage for production of abnormal prion protein in PrP-deficient neuronal cell line

Keywords: Prion protein; PrPSc; PrP gene-deficient cell line

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Lack of PrPsc immunostaining in intracranial ectopic lymphoid follicles in a sheep with concomitant non-suppurative encephalitis and Nor98-like atypical scrapie: A case report

Keywords: Ovine; Atypical scrapie; Lymphotropism; PrPsc

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease

Keywords: AASA; aminoadipic semialdehyde; BSE; bovine spongiform encephalopathy; CEL; N-ɛ-carboxyethyllysine; CJD; Creutzfeldt-Jakob disease; CML; N-ɛ-carboxymethyllysine; DBI; double bond index; GSA; glutamic semialdehyde, 4-HNE, 4-hydroxynonenal; MCO; metal-cat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Mouse-adapted sporadic human Creutzfeldt–Jakob disease prions propagate in cell culture

Keywords: Prion protein; PrPC; PrPSc; Transmissible spongiform encephalopathy; Creutzfeldt–Jakob disease

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins

Keywords: Prion protein; DNA aptamer; SELEX; Transmissible spongiform encephalopathy; PrPSc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

CRBL cells: Establishment, characterization and susceptibility to prion infection

Keywords: PrP; prion protein; PrPC; cellular prion protein; PrPSc; scrapie prion protein disease; CJD; Creutzfeldt-Jakob; p53−/−; p53 null; CRBL; a cell line established from the cerebellum; N2a; Neuro2a; ScN2a; scrapie-infected N2a; SMB; scrapie-infected mouse

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

The key-role of tyrosine 155 in the mechanism of prion transconformation as highlighted by a study of sheep mutant peptides

Keywords: PrP; prion protein; PrPC; “cellular” isoform; PrPSc; “scrapie” isoform; TFE; trifluoroethanol; PBS; phosphate buffer solution; TFE/PBS; 87/13 (v/v) TFE/PBS mixture; CD; circular dichroism; NMR; nuclear magnetic resonance; CSD; chemical shift diffe

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

The ubiquitin-proteasome system in spongiform degenerative disorders

Keywords: AD; Alzheimer's disease; AgRP; Agouti related protein; AIDS; acquired immune deficiency syndrome; APP; amyloid precursor protein; ASPA; aspartoacylase gene; Atrn; attractin; BSE; bovine spongiform encephalopathy; CD; Canavan's spongiform leukodystroph

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2008 سفارش ترجمه

Development of recombinant chicken IgY from single chain fragment of variable region for diagnosis of BSE

Keywords: PrPSc; BSE; Diagnosis; scFv; Recombinant chicken antibody

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Species barriers for chronic wasting disease by in vitro conversion of prion protein

Keywords: CWD; PrPC; PrPSc; In vitro conversion; Species barrier

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Human cellular prion protein hPrPC is sorted to the apical membrane of epithelial cells

Keywords: Epithelial cells; Apical membrane sorting; Human PrPC; PrPSc;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

C1q binding and complement activation by prions and amyloids

Keywords: Alzheimer; Amyloid; C1q; Prion; Scrapie; Transmissible spongiform encephalopathy; Aβ; amyloid β peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; BSE; bovine spongiform encephalopathy; CJD; Creutzfeld-Jacob disease; FBD; familial Briti

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

The neurochemical nature of PrPc-containing cells in the rat brain

Keywords: CB; calbindin; CBP; calcium-binding proteins; CJD; Creutzfeldt-Jakob disease; CR; calretinin; FFI; Fatal Familial Insomnia; PNN; perineuronal nets; PrPC; cellular prion protein; PrPSc; scrapie prion protein; PV; parvalbumin; TSEs; transmissible spongiform

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Antibody-mediated neuronal apoptosis: Therapeutic implications for prion diseases

Keywords: Prion; Anti-prion antibody; Apoptosis; PrPC; PrPSc

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Structure–activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells

Keywords: Prion; PrP; PrPSc; PrPC; 9-Aminoacridine; Quinacrine; ScN2a

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Pathological findings in retina and visual pathways associated to natural Scrapie in sheep

Keywords: PrPsc; Natural Scrapie; Retina; Visual pathways; Sheep; Gliosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Biochemical evidence for the proteolytic degradation of infectious prion protein PrPsc in hamster brain homogenates by foodborne bacteria

Keywords: Prion protein; Scrapie; BSE; PrPSc; Bacterial protease; Degradation; Food

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Selection of ovine PrP high-producer subclones from a transfected epithelial cell line

Keywords: PrPSc; Cultured cells; Rov9; Prion diseases; Sheep

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

FTIR-microspectroscopy of prion-infected nervous tissue

Keywords: Scrapie; PrPSc; PrPC; Synchrotron infrared microspectroscopy; Dorsal root ganglia; Chemical mapping

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Atypical BSE in Germany—Proof of transmissibility and biochemical characterization

Keywords: BSE; Cattle; PrPSc; Biochemical differentiation

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

The N-terminal cleavage site of PrPSc from BSE differs from that of PrPSc from scrapie

Keywords: Prion; Scrapie; BSE; PrPSc; PrPcore; N-terminus;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Aptamers against extracellular targets for in vivo applications

Keywords: Aptamers; SELEX; In vivo; Therapeutic; Diagnostic; 18F; fluorine 18; 2′F; 2′ fluoro; 2′Ome; 2′O methyl; 99mTc; technetium 99 metastable; AchR; acetylcholine receptor; AMD; age-related macular degeneration; DAG; diacylglycerol; ECM; extracellular m

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Use of a new immunoassay to measure PrPSc levels in scrapie-infected sheep brains reveals PrP genotype-specific differences

Keywords: PK; Proteinase K; CDI; conformation-dependent immunoassay; PrPC; normal PrP; PrPSc; disease-associated PrP; TSE; transmissible spongiform encephalopathy; BSE; bovine spongiform encephalopathy; CNS; central nervous system; LRS; lymphoreticular system; IHC;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Detection of ultra-low levels of pathologic prion protein in scrapie infected hamster brain homogenates using real-time immuno-PCR

Keywords: BSE; Immuno-PCR; IPCR; Real-time IPCR; Prion; PrPC; PrPSc; Scrapie; TSE;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Membrane perturbation effects of peptides derived from the N-termini of unprocessed prion proteins

Keywords: PrP; prion protein; PrPC; cellular isoform of PrP; PrPSc; scrapie isoform of PrP; mPrPp; peptide with sequence corresponding to the N-terminus of the mouse prion protein, residues 1-28; bPrPp; peptide with sequence corresponding to the N-terminus of the

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Immunohistochemical Distinction between Preclinical Bovine Spongiform Encephalopathy and Scrapie Infection in Sheep

Keywords: bovine spongiform encephalopathy; BSE; prion protein; PrPSc; scrapie; sheep; third eyelid; tingible body macrophages; tonsil; viral infection;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Expression of PrPC in the rat brain and characterization of a subset of cortical neurons

Keywords: Disorders of the nervous system; Degenerative disease (other); A; anterior complex of the thalamus; CB; calbindin; CBP; calcium-binding proteins; CJD; Creutzfeldt-Jakob disease; CR; calretinin; FFI; fatal familial insomnia; MD; mediodorsal thalamic nucl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

The prion protein gene: Identifying regulatory signals using marsupial sequence

Keywords: PRNP; prion protein gene; PrP; prion protein; PrPC; normal isoform of prion protein; PrPSc; pathogenic isoform of prion protein; SPRN; Shadow of prion protein gene; Sho; Shadow protein; ORF; open reading frame; PCR; polymerase chain reaction; RT-PCR; reve

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه