Keywords: BMI; Body mass index; CVD; Cardiovascular disease; DM; Diabetes mellitus; EOPE; Early onset PE; PWT; Infero-lateral wall thickness; IVS; Interventricular septum; LOPE; Late onset PE; LV; Left ventricular; LVEF; Left ventricular ejection fraction; LVGLS; L
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Keywords: SNL; spinal nerve ligation; ELISA; enzyme-linked immune sorbent; IF; immune fluorescent; PWL; paw thermal withdrawal latency; PWT; paw mechanical withdrawal threshold; TNF-α; tumor necrosis factor alpha; IL-6; interleukin-6; IL-1β; interleukin-1β; IL-1
Keywords: ACSF; artificial cerebrospinal fluid; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CFA; complete Freund's adjuvant; D-APV; D(â)-2-Amino-5-phosphonopentanoic acid; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene
Keywords: CSA; chondrasarcoma; FSA; fibrosarcoma; GI; gastrointestinal tract; GIST; gastrointestinal stromal tumors; GWAS; genome wide association studies; HS; histiocytic sarcoma; HSA; hemangiosarcoma; IHC; immunohistochemistry; LIP; liposarcoma; LMY; leiomyosarco
Keywords: PWT; posterior wall thickness; IVST; interventricular septum thickness; RWT; relative wall thickness; LVEDD; left ventricular end-diastolic diameter; LVESD; left ventricular end-systolic diameter; LV; left ventricular; SAP; systolic arterial pressure; DAP
Keywords: Cilostazol; Obesity; AngiotensinII; Diastolic dysfunction; HFpEF; TGF-β; PKM2; Ciloz; Cilostazol; AngII; AngiotensinII; HFD; High Fat Diet; FS; Fraction Shortening; EF; Ejection Fraction; HFpEF; Heart failure with Preserved Ejection Fraction; PKM2; Pyruv
Keywords: OA; Osteoarthritis; f/f; floxed-floxed, lox P, sandwiching of a DNA sequence; PMM; Partial medial meniscectomy; h; hour; j; Jackson Laboratory; LD; light-dark; DL; dark-light; PWT; paw withdrawal threshold; PTT; paw thermal threshold; DRG; dorsal root gan
Keywords: OA; osteoarthritis; D; day; IA; intra-articular; MIA; monosodium iodoacetate; SP; substance P; CGRP; calcitonin gene related-peptide; BK; bradykinin; STT; somatostatin; (NF)-κB; nuclear factor-kappa B; L; lidocaine; PWT; paw withdrawal threshold; n; numb
Keywords: HFD; high-fat diet; IGF1; Insulin-like Growth Factor 1; IR-KD; inducible insulin receptor knockdown; LFD; low-fat diet; MNCV; motor nerve conduction velocity; PWT; 50% paw withdrawal threshold; TIND; treatment-induced painful neuropathy of diabetes; diabe
Keywords: Left atrial function; Left atrial function index; Cardiovascular diseases; Atrial fibrillation; Epidemiology; Echocardiography; CVD; Cardiovascular disease; LA; Left atrial; LAFI; Left atrial function index; LAmax; Maximum left atrial volume; LAmin; Minim
Keywords: CeA; central nucleus of the amygdala; CRD; colorectal distension; NTS; nucleus tractus solitarius; PENFS; percutaneous, electrical nerve field stimulator; PWT; paw withdrawal threshold; RVM; rostral ventral medulla; TNBS; trinitrobenzenesulfonic acid; VMR
Keywords: SHM; Structural Health Monitoring; AHWT; Adaptive Harmonic Wavelet Transform; PCA; Principal Component Analysis; CWT; Continuous wavelet transform; 2/ATDM; Two Arrival Time Difference Method; 3/ATDM; Three Arrival Time Difference Method; PWT; Piezoelectri
Keywords: AE; Acoustic emission; AHP; Analytic hierarchy process; CCD; Charge coupled device; CIGS; Copper-indium-gallium-selenide; DLIT; Dark lock-in thermography; EBIC; Electron beam induced current; EBSD; Electron backscatter diffraction; EDX; Energy-dispersive
Keywords: Rheumatoid arthritis; Left ventricular systolic dysfunction; Midwall shortening; Longitudinal function; Primary prevention; Cardiovascular risk; C&L; Circumferential and longitudinal; CESS; Circumferential end-systolic stress; CV; Cardiovascular; HF; Hear
Keywords: Aging; Exercise therapy; Muscle strength; Postural balance; Rehabilitation; Resistance training; APDavg; anterior-posterior average displacement; BBS; Berg Balance Scale; Mini-BESTest; Mini-Balance Evaluation Systems Test; MLDavg; medial-lateral average d
Keywords: ANOVA; analysis of variance; CCI; chronic constriction injury; IgG; immunoglobulin G; IL; Interleukin; IR; immunoreactivity; JOR; jaw-opening reflex; MOD; mean optical density; PWT; paw withdrawal threshold; RN; red nucleus; SNI; spared nerve injury; TGF-
Keywords: BAT; brown adipose tissue; UCP1; uncoupling protein 1; UCP1â/â; UCP1-deficient; LV; left ventricle; WT; wild-type; H/R; wall thickness/LV radius; LVMI; LV mass index; cTnI; cardiac troponin I; MI; myocardial infarct; LVEDD; LV end-diastolic diameter;
Keywords: β-FNA; β-funaltrexamine; ANOVA; analysis of variance; CIBP; Cancer-induced bone pain; DRG; dorsal root ganglion; EM2; endomorphin-2; EM2-IP; EM2-immunopositive; MOR; μ opioid receptor; PB; phosphate buffer; PBS; phosphate-buffered saline; POD; post-ope
Keywords: Pearl millet; Phosphorus; Phosphorus uptake efficiency; Phosphorus utilization efficiency; West Africa; aVD; standardized average variance of a difference; CVg; genetic coefficient of variation; BLUP; best linear unbiased predictor; BM; total above-ground
Keywords: urinary incontinence; stress; surgical procedures; minimally invasive; suburethral slings; female; CST; cough stress test; IIQ-7; Incontinence Impact Questionnaire-Short Form; PGI-I; Patient Global Impression of Improvement; PWT; pad weight test; SAE; ser
Keywords: ZIP; zeta pseudosubstrate inhibitory peptide; PKMζ; protein kinase m zeta; S-ZIP; scrambled-zeta pseudosubstrate inhibitory peptide; LTP; long-term potentiation; PAG; midbrain periaqueductal gray; ACC; anterior cingulate cortex; RVM; rostral ventromedial
Norepinephrine-induced downregulation of GLT-1 mRNA in rat astrocytes
Keywords: Astrocyte; Descending inhibitory pathway; Glutamate transporter; Neuropathic pain; Norepinephrine; Spinal cord; ANOVA; analysis of variance; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's Modified Eagle's Medium; EDTA; ethylenediaminetetraacetic
Corticotropin-Releasing Factor in the Brain and Blocking Spinal Descending Signals Induce Hyperalgesia in the Latent Sensitization Model of Chronic Pain
Keywords: ANOVA; analysis of variance; CeA; central amygdala; CFA; complete Freund's adjuvant; CRF; corticotropin-releasing factor; HPA; hypothalamic-pituitary-adrenal; i.c.v.; intracerebroventricular; i.th.; intrathecal; NTX,; naltrexone; NK1R; neurokinin 1
Lycium barbarum polysaccharide protects diabetic peripheral neuropathy by enhancing autophagy via mTOR/p70S6K inhibition in Streptozotocin-induced diabetic rats
Keywords: LBP; Lycium barbarum polysaccharide; DM; diabetes mellitus; DPN; diabetic peripheral neuropathy; LC3-II; microtubule-associated protein 1 light chain 3-II; HDL; high density lipoprotein; SC; Schwarm cell; STZ; streptozotocin; LA; lipoic acid; PWT; paw wit
Spinal SHP2 Contributes to Exaggerated Incisional Pain in Adult Rats Subjected to Neonatal and Adult Incisions via PI3K
Keywords: AMPA receptor; α-amino-3-hydroxy-5-methy-4-isoxazole propionate receptor; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; DRG; dorsal root ganglion; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol-bis(β-aminoethyl ethe
Increased Neuroligin 2 Levels in the Postsynaptic Membrane in Spinal Dorsal Horn may Contribute to Postoperative Pain
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; CPS; cumulative pain score; PSD-95; postsynaptic density protein 95; PWT; paw withdrawal threshold; siRNA; small interfering ribonucleic acid; TTBS; Tween/Tris-buffered saline solution; postoperati
Blockade of vascular endothelial growth factor receptor-1 (Flt-1), reveals a novel analgesic for osteoarthritis-induced joint pain
Keywords: OA; osteoarthritis; PMM; partial medial meniscectomy; h; hour; PWT; paw withdrawal threshold; PTT; paw thermal threshold; DRG; dorsal root ganglion; IT; intrathecal; IA; intraarticular; RT-PCR; Real-time polymerase chain reaction; P; probability; SEM; sta
Neurotoxic effect of oxaliplatin: Comparison with its oxalate-free analogue cis-[PtII(1R,2R-DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)] (LLC-1402) in mice
Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATF3; activating transcription factor 3; CREB; cyclic AMP response element binding protein; DACH; diaminocyclohexane; DRG; dorsal root ganglia; iNOS; inducible nitric oxide synthase; LLC-1402
Peptide welding technology - A simple strategy for generating innovative ligands for G protein coupled receptors
Keywords: Peptides; GPCR; PWT; Nociceptin/orphanin FQ; Opioids; Neurokinins; Neuropeptide S;
Astaxanthin ameliorates behavioral and biochemical alterations in in-vitro and in-vivo model of neuropathic pain
Keywords: AD; Alzheimer's disease; BBB; blood brain barrier; BSA; bovine serum albumin; CNS; central nervous system; CCI; chronic constriction injury; DMSO; dimethylsulphoxide; DTNB; 5,5â²-dithio-bis-[2-nitrobenzoic acid]; FBS; fetal bovine serum; FITC; fluoresc
Suppression of Pax2 Attenuates Allodynia and Hyperalgesia through ET-1-ETAR-NFAT5 Signaling in a Rat Model of Neuropathic Pain
Keywords: ET-1; Endothelin-1; ETAR; endothelin receptor type A; ETBR; Endothelin receptor type B; FISH; fluorescence in situ hybridization; MAPK; mitogen-activated protein kinases; NFAT5; nuclear factor of activated T-cells 5; NF-κB; nuclear factor-kappa B; Pax2;
BDNF contributes to the neonatal incision-induced facilitation of spinal long-term potentiation and the exacerbation of incisional pain in adult rats
Keywords: Brain-derived neurotrophic factor; Incisional pain; Long-term potentiation; Neonatal rat; Spinal dorsal horn; ACC; the anterior cingulate cortex; AMPAR; α-amino-3-hydroxy-5-methy-4-isoxazole propionate (AMPA) receptor; ANOVA; analysis of variance; BDNF;
Silencing of FKBP51 alleviates the mechanical pain threshold, inhibits DRG inflammatory factors and pain mediators through the NF-kappaB signaling pathway
Keywords: FKBP51; FK506 binding protein 51; CCI; chronic constriction injury; PWT; paw withdrawal threshold; PWL; paw withdrawal latency; DRG; dorsal root ganglion; FKBP51; Neuro-inflammation; Neuropathic pain; NF-κB signaling;
Adenosine A1 receptor potentiated glycinergic transmission in spinal cord dorsal horn of rats after peripheral inflammation
Keywords: Adenosine; Glycine receptors; Inflammatory pain; cAMP-dependent protein kinase; G protein-coupled receptor; GlyRs; glycine receptors; A1R; adenosine A1 receptor; PKA; cAMP-dependent protein kinase; CFA; Complete Freund's Adjuvant; PWT; paw withdrawal thre
Flow cytometry analysis of inflammatory cells isolated from the sciatic nerve and DRG after chronic constriction injury in mice
Keywords: DRG; dorsal root ganglion; PWT; paw withdrawal thresholds; CCI; chronic constriction injury; FACS; flow cytometry cell sorting; PFA; paraformaldehyde; DAPI; 4â², 6-diamidino-2-phenylindole; BSA; bovine serum albumin; HEPES; 4-(2-hydroxyethyl)-1-piperazin
Immunoproteomics of tree of heaven (Ailanthus atltissima) pollen allergens
Keywords: AAP; A. altissima pollen; I.U.I.S; International Union of Immunological Societies; 1D; one-dimensional gel; 2D; two-dimensional gel; 1-DE; one-dimensional gel electrophoresis; 2-DE; two-Dimensional Gel Electrophoresis; 2D-PAGE; two-dimensional- polyacryla
Downregulations of TRPM8 expression and membrane trafficking in dorsal root ganglion mediate the attenuation of cold hyperalgesia in CCI rats induced by GFRα3 knockdown
Keywords: TRPM8; transient receptor potential melastatin 8; CCI; chronic constriction injury; DRG; dorsal root ganglion; GFRα3; glial cell line-derived neurotrophic factor family receptor alpha3; siRNA; small interfering RNA; TRP; transient receptor potential; dsR
Up-regulation of CXCL1 and CXCR2 contributes to remifentanil-induced hypernociception via modulating spinal NMDA receptor expression and phosphorylation in rats
Keywords: CFA; complete freund's adjuvant; CXCL1; chemokine (C-X-C motif) ligand 1; GAPDH; glyceraldehydes 3-phosphate dehydrogenase; GSK-3β; glycogen synthase kinase-3β; i.t.; intrathecally; i.v.; intravenously; NMDA; N-methyl-d-aspartate; NS; normal saline; P
Anti-hypersensitive effect of intramuscular administration of αO-conotoxin GeXIVA[1,2] and GeXIVA[1,4] in rats of neuropathic pain
Keywords: nAChR; nicotinic acetylcholine receptor; AUC; area under curve; CCI; chronic constriction injury; PWT; paw withdrawal threshold; αO-Conotoxin GeXIVA[1,2]; αO-Conotoxin GeXIVA[1,4]; Neuropathic pain; Mechanical hyperalgesia; Thermal pain;
A new model of nerve injury in the rat reveals a role of Regulator of G protein Signaling 4 in tactile hypersensitivity
Keywords: CB1 receptor; cannabinoid type-1 receptor; DRG; dorsal root ganglion; GFAP; glial fibrillary acidic protein; Iba1; ionized calcium-binding adapter molecule 1; MPE; maximum-possible-effect; mSNI; modified spared nerve injury; PWT; paw withdrawal threshold;
Participation of peripheral TRPV1, TRPV4, TRPA1 and ASIC in a magnesium sulfate-induced local pain model in rat
Keywords: [d (g)]; difference in pressures; AA%; analgesic activity; AITC; allyl isothiocyanate; ANOVA; analysis of variance; ASIC; acid-ion sensing channel; MS; magnesium sulfate; NMDA; N-methyl-d-aspartate receptors; NO; nitric oxide; PWT; paw withdrawal thresho
PKA is required for the modulation of spinal nociceptive information related to ephrinB-EphB signaling in mice
Keywords: ANOVA; analysis of variance; cAMP; cyclic adenosine monophosphate; CCI; chronic constrictive injury; DMSO; dimethyl sulfoxide; DRG; dorsal root ganglion; NMDA; N-methyl-d-aspartate; CREB; cAMP-response element-binding protein; p-CREB; phosphorylated cAMP-
Lipoxin A4 attenuates radicular pain possibly by inhibiting spinal ERK, JNK and NF-κB/p65 and cytokine signals, but not p38, in a rat model of non-compressive lumbar disc herniation
Keywords: ANOVA; analysis of variance; CCD; chronic compression of dorsal root ganglion; CCI; chronic constrictive injury; DRG; dorsal root ganglion; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal-regulated kinase; IL; interleukin; JNK; C-Jun N
Inhibition of DOR prevents remifentanil induced postoperative hyperalgesia through regulating the trafficking and function of spinal NMDA receptors in vivo and in vitro
Keywords: ACSF; artificial cerebral spinal fluid; DOR; delta opioid receptor; DRG; dorsal root ganglion; EGFR; epidermal growth factor receptor; GSK-3β; glycogen synthase kinase-3β; mEPSC; miniature excitatory postsynaptic current; NMDA; N-methyl-d-aspartate; OIH
Osteoarthritis-dependent changes in antinociceptive action of Nav1.7 and Nav1.8 sodium channel blockers: An in vivo electrophysiological study in the rat
Keywords: C-LTMs; C-low-threshold mechanoreceptors; DRG; dorsal root ganglia; KO; knockout; MIA; monosodium iodoacetate; NSAIDs; non-steroidal anti-inflammatory drugs; OA; osteoarthritis; PWF; paw withdrawal frequency; PWT; paw withdrawal threshold; RM ANOVA; repea
BDNF contributes to the development of neuropathic pain by induction of spinal long-term potentiation via SHP2 associated GluN2B-containing NMDA receptors activation in rats with spinal nerve ligation
Keywords: ACC; the anterior cingulate cortex; AMPAR; a-amino-3-hydroxy-5-methy-4-isoxazole propionate (AMPA) receptor; ANOVA; analysis of variance; AUC; area under the time-course curve; BDNF; brain-derived neurotrophic factor; CREB; cAMP response element-binding p
Activation of spinal GABAB receptors normalizes N-methyl-D-aspartate receptor in diabetic neuropathy
Keywords: NMDA; N-methyl-D-aspartate; NMDAR; N-methyl-D-aspartate receptor; PWT; paw withdrawal threshold; STZ; streptozotocin; CREB; cAMP response element-binding; p-CREB; phosphorylated CREB; Diabetic neuropathic pain; Spinal dorsal horn; GABAB receptor; Glutamat
Probing selected structural regions in the secreted phospholipase A2 from Arabidopsis thaliana for their impact on stability and activity
Keywords: Secreted phospholipase A2 from Arabidopsis thaliana; Trp variants; Structure-stability relationship; Activity; N-Terminal deletion; AtPLA2α; sPLA2α from Arabidopsis thaliana; bpPLA2; sPLA2 from bovine pancreas; bvPLA2; sPLA2 from bee venom; DOPC; 1,2-
The antinociceptive effect of reversible monoamine oxidase-A inhibitors in a mouse neuropathic pain model
Keywords: ANOVA; analysis of variance; CCI; chronic constriction injury; 2-DMPI; 2-(3,4-dimethoxy-phenyl)-4,5-dihydro-1H-imidazole; GABA; γ-amino butyric acid; 4-HQ; 4-hydroxyquinoline; 5-HT; 5-hydroxytryptamine; ID50; 50% inhibitory dose; Imax; maximum inhibition
Research ReportmTOR and its downstream pathway are activated in the dorsal root ganglion and spinal cord after peripheral inflammation, but not after nerve injury
Keywords: CFA; complete Freund's adjuvant; DRG; dorsal root ganglion; mTOR; mammalian target of rapamycin; PWL; paw withdrawal latency; PWT; paw withdrawal threshold; RT; room temperature; S6K1; p70 ribosomal S6 protein kinase 1; SNL; spinal nerve ligation; mTOR; I