Keywords: Pattern-recognition receptors (PRRs); Toll-like receptors (TLRs); RIG-I-like receptors (RLRs); NOD-like receptors (NLRs); Small molecule modulators; BIR; baculovirus inhibitor repeat; CARD; caspase recruitment domains; CFS; chronic fatigue syndrome; CLR;
مقالات ISI (ترجمه نشده)
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Keywords: ADAM; a disintegrin and metalloproteinase; APP; amyloid precursor protein; APC; antigen presenting cell; Aβ; β-amyloid; B7-H1; B7-homolog 1; CARD; caspase activation and recruitment domain; CCR; C-C chemokine receptor; CIM; C-protein induced myositis; C
Keywords: Death domain; Inflammasome; NALP3; PYD; ASC; ASC2; Molecular modeling; MD simulation; Docking;
Keywords: AIM2; absent in melanoma-2; ASC; apoptosis-associated speck-like protein containing a CARD; ATP; adenosine triphosphate; CAPS; cryopyrin-associated periodic syndromes; CARD; caspase recruitment domain; DAMP; danger-associated molecular pattern; DNA; deoxy
Keywords: CARD; caspase recruitment domain; CC; coiled coil; DAMP; danger-associated molecular pattern; DD; death domain; DED; death effector domain; NBD; nucleotide-binding domain; NLR; nucleotide binding and oligomerization domain (NOD) leucine-rich repeat (LRR)-
Keywords: α-HL; α-hemolysin; AIM2; absent in melanoma; ASC; apoptosis-associated speck-likeprotein containing a CARD; BIR; baculoviral inhibitor of apoptosis repeat; CARD; caspase activation and recruitment domain; Caspase; cysteine aspartic acid-specific proteas
Keywords: RJ; royal jelly; OVX; ovariectomy; Hyp; hydroxyproline; PYD; pyridinoline; DPD; deoxypyridinoline; LH; lysyl hydroxylase; MRJP; major royal jelly protein; Royal jelly; Bone quality; Collagen crosslink; Type I collagen; Lysyl hydroxylase;
Keywords: BAP; bone-specific alkaline phosphatase; BCE; bone collagen equivalents; BSP; bone sialoprotein; CLIA; chemoluminescence immunoassay; CREA; urinary creatinine; CTX; carboxy-terminal cross-linking telopeptide of type I collagen; DPD; deoxypyridinoline (lys
The role of the NLRP3 inflammasome and the activation of IL-1β in the pathogenesis of chronic viral hepatic inflammation
Keywords: CHB; chronic hepatitis B; CHC; chronic hepatitis C; NLRP3; NACHT, LRR, and PYD domains-containing protein 3/cryopyrin; LRR; leucine-rich repeat; NACHT; nucleotide-binding and oligomerization domain; NAD; NACHT-associated domain; NBD; nucleotide-binding do
AIM2 inflammasome activation and regulation: A structural perspective
Keywords: AIM2; Inflammasome; Helical filament; High-order assembly; Polymerization; ASC; Caspase-1; PYD; CARD; P202; INCA;
Conformation switching of AIM2 PYD domain revealed by NMR relaxation and MD simulation
Keywords: AIM2; PYD; NMR; MD; Conformation exchange; AIM2; absent in melanoma 2; PYD; pyrin domain; NMR; nuclear magnetic resonance; ASC; apoptosis-associated speck-like protein containing a caspase-activation and recruitment domain (CARD); CARD; caspase-activation
The NMR solution structure of AIM2 PYD domain from Mus musculus reveals a distinct α2-α3 helix conformation from its human homologues
Keywords: Inflammasome; AIM2; PYD; NMR; Solution structure; Self-association;
ATP binding by NLRP7 is required for inflammasome activation in response to bacterial lipopeptides
Keywords: acLP; acetylated lipopeptides; ASC; apoptosis-associated speck-like protein containing a CARD; ATPase; adenosine triphosphatases; CARD; caspase recruitment domain; DAMP; damage associated molecular pattern; FLICA; fluorescent labeled inhibitor of caspase-
How is inflammation initiated? Individual influences of IL-1, IL-18 and HMGB1
Keywords: AIM 2; absent in melanoma 2; ASC; apoptosis-associated speck-like protein containing a caspase activation and recruitment domain; CAPS; cryopyrin-associated periodic syndromes; CARD; Caspase Activation and Recruitment Domain; Casp1; Caspase-1; DAMP; dange
The emerging role of human PYHIN proteins in innate immunity: Implications for health and disease
Keywords: AIM2; absent in melanoma 2; ALR; AIM2-like receptor; ASC; apoptosis-associated speck-like protein containing a CARD; CARD; caspase activation and recruitment domain; cGAMP; cyclic GMP-AMP; cGAS; cGAMP synthase; DAI; DNA-dependent activator of IFN-regulato
Injury-induced immune responses in Hydra
Keywords: AMPs; antimicrobial peptides; AP1; activator protein-1; ank; ankyrin repeat; BIR; baculovirus inhibitor of apoptosis protein repeat; CARD; caspase recruitment domain; CC; coiled coil domain; CBP; CREB binding protein; CREB; cAMP response element binding p
The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease
Keywords: CD, Crohn disease; NLR, NOD-like receptor; ROS, reactive oxygen species; IBD, inflammatory bowel disease; GWAS, genome wide association study; NOD, nucleotide binding and oligomerisation domain; LRR, leucine-rich repeats; EBD, effector binding domain; PYD
PYRIN domain of NALP2 inhibits cell proliferation and tumor growth of human glioblastoma
Keywords: PYD; NALP2; Cell proliferation; Glioblastoma; NF-κB
Type 2 diabetic mice demonstrate slender long bones with increased fragility secondary to increased osteoclastogenesis
Keywords: 8-OHdG; 8-hydroxydeoxyguanosine, an oxidized nucleoside of DNA; αMEM; α-modified minimum essential medium; AGE; advanced glycation end products; BMD; areal bone mineral density measured by DEXA; DEXA; dual energy X-ray absorptiometry; FVB/N; Friend viru
NOD-like subfamily of the nucleotide-binding domain and leucine-rich repeat containing family receptors and their expression in channel catfish
Keywords: BIR; baculovirus inhibitor of apoptosis protein repeat; CARD; caspase recruitment domain; CIITA; class IImajor histocompatibility complex, transactivator; HET-E; bacterial nucleotide triphosphatase protein; IPAF; ice protease-activating factor; LRR; leuci
Polychaetoid controls patterning by modulating adhesion in the Drosophila pupal retina
Keywords: Adhesion; Pyd; Polychaetoid; Eye; Epithelia; Patterning
The cytosolic pattern-recognition receptor Nod2 and inflammatory granulomatous disorders
Keywords: Apaf-1; apoptotic protease activating factor 1; CARD; caspase-recruitment domain; IL-1β; interleukin 1β; LPS; lipopolysaccharide; MDP; muramyl-dipeptide; NF-κB; nuclear factor κB; NOD; nucleotide-binding oligomerization domain; PYD; pyrin domain; R ge