Keywords: پیرووات دهیدروژناز پیچیده; Observer-reported outcome measure; Clinical trial; Rare disease; Dichloroacetate; Pyruvate dehydrogenase complex;
مقالات ISI پیرووات دهیدروژناز پیچیده (ترجمه نشده)
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Keywords: پیرووات دهیدروژناز پیچیده; PDC; pyruvate dehydrogenase complex; TCA; tricarboxylic acid cycle; PKM2; pyruvate dehydrogenase kinase 2; HMGB1; high mobility group box 1 protein; LPS; lipopolysaccharide; SDH; succinate dehydrogenase; ETC; electron transport chain; PHD; prolyl hydroxyl
Keywords: پیرووات دهیدروژناز پیچیده; DEGs; Differentially expressed genes; RPKM; Reads per kilobase per million mapped reads; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; IAA; Auxin; CK; Cytokinin; SSH; Suppression subtractive hybridization; N. tabacum; Nicotiana tabacum
Keywords: پیرووات دهیدروژناز پیچیده; AC; arm circumference; APMT; adductor pollicis muscle thickness; BCAA; branched-chain amino acids; BCKA; branched-chain ketoacids; BMI; body mass index; CAMA; corrected mid-arm muscle area; CBF; cerebral blood flow; EEG; electroencephalogram; FDR; false d
Keywords: پیرووات دهیدروژناز پیچیده; Pyruvate dehydrogenase complex; Lactate dehydrogenase; Acute liver failure; Galloflavin;
Keywords: پیرووات دهیدروژناز پیچیده; Docosahexaenoic acid; Eicosapentaenoic acid; Lipid droplets; Phaeodactylum tricornutum; Polyunsaturated fatty acid; Triacylglycerol; ACCase; acetyl-CoA carboxylase; ACP; acyl carrier protein; ALA; α-linolenic acid; ATS1; plastidic glycerol-3-phosphate ac
Keywords: پیرووات دهیدروژناز پیچیده; Proliferation; Target; Pyruvate dehydrogenase kinase; Pyruvate dehydrogenase complex;
Keywords: پیرووات دهیدروژناز پیچیده; hE1o; human 2-oxoglutarate dehydrogenase; hE2o; human dihydrolipoyl succinyltransferase; hE3; human dihydrolipoyl dehydrogenase; hOGDHc; human 2-oxoglutarate dehydrogenase complex; PDC; pyruvate dehydrogenase complex; ecE1o; E. coli 2-oxoglutarate dehydro
Keywords: پیرووات دهیدروژناز پیچیده; DCA; Dichloroacetate; ECAR; extra cellular acidification rate; JC-1; 5,5â²,6,6â²-tetrachloro-1,1â²,3,3â²-tetraethylbenzimidazolycarbocyanine; MMP; ÎÏm, mitochondrial membrane potential; NAD+; Â nicotinamide adenine dinucleotide; NADH; reduced nicoti
Keywords: پیرووات دهیدروژناز پیچیده; ETC; electron transport complexes; ROS/RNS; reactive oxygen or nitrogen spices; âÏm; mitochondrial inner membrane potential; TCA; TriCarboxylic acid cycle; MPTP; mitochondrial permeability transition pore; mtDNA; mitochondrial DNA; ND5; NADH dehydrogen
Keywords: پیرووات دهیدروژناز پیچیده; Allergy; mast cells; degranulation; cytokines; pyruvate dehydrogenase; microphthalmia transcription factor; asthma; mitochondria; AHR; Airway hyperresponsiveness; BALF; Bronchoalveolar lavage fluid; BMMC; Bone marrow-derived mast cell; CBMC; Cord bloodâ
Keywords: پیرووات دهیدروژناز پیچیده; Blood mitochondrial enzymes; Complex I; Complex IV; Predictors of outcome; Pyruvate dehydrogenase complex; Severe traumatic brain injury
Keywords: پیرووات دهیدروژناز پیچیده; 13dpg; 3-phospho-d-glyceroyl phosphate; 2pg; glycerate 2-phosphate; 3pg; 3-phospho-d-glycerate; 6pgc; 6-phospho-d-gluconate; 6pgl; 6-phospho-d-glucono-1,5-lactone; ac; acetate; acald; acetaldehyde; accoa; acetyl-CoA; actp; acetyl phosphate; coa; coenzyme
Keywords: پیرووات دهیدروژناز پیچیده; AMPK; AMP-activated protein kinase; BM; bone marrow; CAT; catalase; Complex I; NADH-coenzyme Q oxidoreductase; Complex II; succinate-coenzyme Q oxidoreductase; Complex III; ubiquinol-cytochrome c oxidoreductase; COX; cytochrome c oxidase; Complex V; FoF1A
Keywords: پیرووات دهیدروژناز پیچیده; L:P; lactate to pyruvate; PDC; pyruvate dehydrogenase complex; TCA; tricarboxylic acid cycle; Lactate; Pyruvate; Lactate to pyruvate ratio; Lactic acidosis; Perchloric acid;
Keywords: پیرووات دهیدروژناز پیچیده; Pyruvate Dehydrogenase Complex; Glucose metabolism; Heart disease;
Keywords: پیرووات دهیدروژناز پیچیده; PET; photosynthetic electron transport; NADPH; nicotinamide adenine dinucleotide phosphate; ATP; adenosine triphosphate; CO2; carbon dioxide; Cytb6f; cytochrome b6f complex; PSI; photosystem I; PSII; photosystem II; LHC; light-harvesting complex; MGDG; mo
Keywords: پیرووات دهیدروژناز پیچیده; OGDHc; 2-oxoglutarate (also known as alpha-ketoglutarate) dehydrogenase complex; PDHc; pyruvate dehydrogenase complex; OG; 2-oxoglutarate; cyt c; cytochrome c; LA; lipoic acid; EDTA; ethylene diamine tetraacetic acid; FAD; flavin adenine dinucleotide; LAD
Keywords: پیرووات دهیدروژناز پیچیده; PDC; pyruvate dehydrogenase complex; PDH; pyruvate dehydrogenase; DCA; dichloroacetic acid; Biogenic polyamine; Lactic acidosis; Phenformin; Spermidine;
Keywords: پیرووات دهیدروژناز پیچیده; Corynebacterium glutamicum; Pyruvate dehydrogenase complex; Metabolic engineering; Amino and organic acid production; Isobutanol production;
Keywords: پیرووات دهیدروژناز پیچیده; mitochondria; oxygen consumption rate; pyruvate dehydrogenase complex; renal proximal tubule; systolic blood pressure;
Keywords: پیرووات دهیدروژناز پیچیده; CSF; cerebrospinal fluid; DCA; dichloroacetate; EDTA; ethylenediaminetetraacetic acid; GSTZ1; glutathione transferase zeta 1; MA; maleylacetone; MAAI; maleylacetoacetate isomerase; MELAS; mitochondrial encephalomyopathy, lactic acidosis and stroke-like ep
Keywords: پیرووات دهیدروژناز پیچیده; RC; respiratory chain; PDH; pyruvate dehydrogenase; BCAAs; branched chain amino acids; CK; creatine kinase; PC; pyruvate carboxylase; PDHc; pyruvate dehydrogenase complex; Primary human mitochondrial disease; Pyruvate dehydrogenase deficiency; Metabolites
Keywords: پیرووات دهیدروژناز پیچیده; AD; Alzheimer's disease; ADNI; Alzheimer Disease Neuroimaging Initiative; AGE; advanced glycation end products; ER; endoplasmic reticulum; FDG-PET; Fluoro-DeoxyGlucose-Positron Emission Tomography; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; KGDHC; Î
Keywords: پیرووات دهیدروژناز پیچیده; PDC; pyruvate dehydrogenase complex; TPP; thiamine pyrophosphate; 2D-BN/SDS-PAGE; two dimensional blue native SDS-PAGE; Photorespiration; Heat shock protein Hsp93-V; Two-dimensional BN/SDS-PAGE;
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships
Keywords: پیرووات دهیدروژناز پیچیده; Pyruvate dehydrogenase kinase; Pyruvate dehydrogenase complex; Antiproliferative activity; Dichloroacetophenone; Kinase inhibition;
Altering the sensitivity of Escherichia coli pyruvate dehydrogenase complex to NADH inhibition by structure-guided design
Keywords: پیرووات دهیدروژناز پیچیده; Pyruvate dehydrogenase complex; Dihydrolipoamide dehydrogenase; NADH inhibition; Protein engineering;
Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase
Keywords: پیرووات دهیدروژناز پیچیده; h; human; E3; (dihydro)lipoamide dehydrogenase, the common E3 component of the mitochondrial 2-oxo acid dehydrogenase complexes; LADH; (dihydro)lipoamide dehydrogenase; KGDHc; alpha-ketoglutarate (also known as 2-oxoglutarate) dehydrogenase complex; PDHc;
Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1α/mitochondrial biosynthesis pathway
Keywords: پیرووات دهیدروژناز پیچیده; ADH; alcohol dehydrogenase; ALD; Alcoholic liver disease; ALDH; aldehyde dehydrogenase; CPT-1α; carnitine palmitoyl transterase-1α; CR; calorie restriction; CS; citrate synthase; CYP2E1; cytochrome P450 2E1; FASN; fatty acid synthase; NAD+; nicotinamide
Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1
Keywords: پیرووات دهیدروژناز پیچیده; PDK; pyruvate dehydrogenase kinase; PDC; pyruvate dehydrogenase complex; MMP; mitochondrial membrane potential; ROS; reactive oxygen species; OXPHOS; oxidative phosphorylation; TCA; tricarboxylic acid; PDPs; pyruvate dehydrogenase phosphatases; DCA; dichl
Design and characterization of α-lipoic acyl shikonin ester twin drugs as tubulin and PDK1 dual inhibitors
Keywords: پیرووات دهیدروژناز پیچیده; Cancer; Shikonin; Twin drug; Pyruvate dehydrogenase kinase; Tubulin; CADD; computer assistant drug design; NOS; nitric oxide synthase; PKM2; pyruvate kinase isozymes M2; GLUT1; Glucose transporter 1; LA; alpha-lipoic acid; PDH; pyruvate dehydrogenase; PDC
Lipomyces starkeyi: Its current status as a potential oil producer
Keywords: پیرووات دهیدروژناز پیچیده; 5-HMF; 5-hydroxymethylfurfural; ACL; ATP citrate lyase; AMP; Adenosine mono phosphate; ATP; Adenosine Tri Phosphate; ARA; arachidonic acid; DHA; docosahexanoic acid; EPA; eicosapentanoic acid; GLA; Gamma linoleic acid; C/N; Carbon to Nitrogen; CoA; Coenzy
Transcriptomic analysis of Momordica charantia polysaccharide on streptozotocin-induced diabetic rats
Keywords: پیرووات دهیدروژناز پیچیده; M. charantia; Momordica charantia; RNA-seq; RNA sequencing; T2DM; Type 2 diabetes mellitus; IR; insulin resistance; PPAR; peroxisome proliferator-activated receptor; FBG; fasting blood glucose; G6Pase; glucose-6-phosphatase; PEPCK; phosphoenol pyruvate ca
Neuron-specific knockdown of Drosophila PDHB induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting
Keywords: پیرووات دهیدروژناز پیچیده; PDC; pyruvate dehydrogenase complex; PDH; pyruvate dehydrogenase; PDHA; pyruvate dehydrogenase alpha; PDHB; pyruvate dehydrogenase beta; PDCD; pyruvate dehydrogenase complex deficiency; NMJ; neuromuscular junction and GAPDH, Glyceraldehyde-3-phosphate deh
Human dihydrolipoamide dehydrogenase (E3) deficiency: Novel insights into the structural basis and molecular pathomechanism
Keywords: پیرووات دهیدروژناز پیچیده; E3-deficiency; Dihydrolipoamide dehydrogenase; Alpha-ketoglutarate dehydrogenase complex; Pyruvate dehydrogenase complex; Pathogenic mutation; KGDHc; alpha-ketoglutarate (also known as 2-oxoglutarate) dehydrogenase complex; KG; alpha-ketoglutarate; PDHc;
Enzymatic testing sensitivity, variability and practical diagnostic algorithm for pyruvate dehydrogenase complex (PDC) deficiency
Keywords: پیرووات دهیدروژناز پیچیده; PDC; pyruvate dehydrogenase complex; CI; confidence interval; TGP; targeted gene panel; TAT; turn-around-time; RR; reference range; WES; whole exome sequencing; WGS; whole genome sequencing; Biochemical testing; Sensitivity; Variability; Diagnostic algori
Pyruvate dehydrogenase complex regulator (PdhR) gene deletion boosts glucose metabolism in Escherichia coli under oxygen-limited culture conditions
Keywords: پیرووات دهیدروژناز پیچیده; PdhR; Pyruvate dehydrogenase complex; NADH dehydrogenase-2; NAD+/NADH ratio; Acetic acid; Redox balance;
Lethal neonatal case and review of primary short-chain enoyl-CoA hydratase (SCEH) deficiency associated with secondary lymphocyte pyruvate dehydrogenase complex (PDC) deficiency
Keywords: پیرووات دهیدروژناز پیچیده; SCEH; short-chain enoyl-CoA hydratase; PDC; pyruvate dehydrogenase complex; KDC; α-ketoglutarate dehydrogenase complex; MDHB; 2-methyl-2,3-dihydroxybutyric acid; WES; whole exome sequencing; RR; reference range; DOL; day-of-life; Short-chain enoyl-CoA hy
Succinyl-CoA synthetase (SUCLA2) deficiency in two siblings with impaired activity of other mitochondrial oxidative enzymes in skeletal muscle without mitochondrial DNA depletion
Keywords: پیرووات دهیدروژناز پیچیده; SUCL; succinyl-CoA ligase; A-SCS; succinyl-CoA synthetase (ADP-forming); SM; skeletal muscle; PDC; pyruvate dehydrogenase complex; KDC; α-ketoglutarate dehydrogenase complex; PEPCK; phosphoenolpyruvate carboxykinase; ETC; electron transport chain; WES; w
Liver immunology: How to reconcile tolerance with autoimmunity
Keywords: پیرووات دهیدروژناز پیچیده; PPR; pattern recognition receptor; HBV; hepatitis B virus; HCV; hepatitis C virus; TLR; toll-like receptor; IFN; interferon; LSEC; liver sinusoidal endothelial cell; APC; antigen presenting cell; MHC; major histocompatibility complex; PDL-1; program death
Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells
Keywords: پیرووات دهیدروژناز پیچیده; Pyruvate dehydrogenase kinase; Pyruvate dehydrogenase complex; Anti-proliferation; Binding affinity;
Genome wide identification of microRNAs involved in fatty acid and lipid metabolism of Brassica napus by small RNA and degradome sequencing
Keywords: پیرووات دهیدروژناز پیچیده; sRNA; small RNA; miRNA; micro RNA; ACSL; long-chain acyl-CoA synthetase; DAF; day after flowering; GO; gene ontology; KEGG; terms and Kyoto Encyclopedia of Genes and Genomes; ANOVA; Analysis of Variance; qRT-PCR; Quantitative Real time PCR; ARF; auxin res
New insights on the organization and regulation of the fatty acid biosynthetic network in the model higher plant Arabidopsis thaliana
Keywords: پیرووات دهیدروژناز پیچیده; Arabidopsis; Fatty acids; Chloroplast; Biosynthetic pathway; Regulation; ACC; acetyl-CoA carboxylase; ACP; acyl-carrier protein; BC; biotin carboxylase; BCCP; biotin carboxyl-carrier protein; CT; carboxyltransferase; FA; fatty acid; FAS; fatty acid syntha
Pathogenic mechanisms underlying X-linked Charcot-Marie-Tooth neuropathy (CMTX6) in patients with a pyruvate dehydrogenase kinase 3 mutation
Keywords: پیرووات دهیدروژناز پیچیده; X-linked Charcot-Marie-Tooth neuropathy; Pyruvate dehydrogenase kinase 3; Pyruvate dehydrogenase complex; Mitochondria; Patient fibroblasts; Dichloroacetic acid;
The role of AMPK in cardiomyocyte health and survival
Keywords: پیرووات دهیدروژناز پیچیده; ADP; Adenosine diphosphate; AICAR; 5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside; AMPK; Adenosine monophosphate-activated protein kinase; CaMKKβ; Calmodulin-dependent protein kinase kinase beta; CPT1; Carnitine palmitoyltransferase 1; eNOS; Endoth
Alterations in the cardiac proteome of the spontaneously hypertensive rat induced by transgenic expression of CD36
Keywords: پیرووات دهیدروژناز پیچیده; ABC; ammonium bicarbonate; ACN; acetonitrile; BLAST; Basic Local Alignment Search Tool; CBB; coomassie brilliant blue; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; 2DE; two-dimensional gel electrophoresis; DTT; dithiothreitol; EDTA; e
GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate
Keywords: پیرووات دهیدروژناز پیچیده; [Clâ]; chloride concentration; DCA; dichloroacetate; ERK; extracellular signal-regulated kinase; GSTZ1; glutathione transferase Z1; HER2; human epidermal growth factor receptor 2; PDC; pyruvate dehydrogenase complex; PDK; pyruvate dehydrogenase kinase;
Targeting respiratory complex I to prevent the Warburg effect
Keywords: پیرووات دهیدروژناز پیچیده; OXPHOS; oxidative phosphorylation; CI; complex I; ROS; reactive oxygen species; TCA; tricarboxylic acid; PARP1; poly (ADP ribose) polymerase 1; AMPK; AMP activated kinase; mTORC1; mammalian target of rapamycin complex 1; HIF1α; hypoxia inducible factor 1
Structural alterations by five disease-causing mutations in the low-pH conformation of human dihydrolipoamide dehydrogenase (hLADH) analyzed by molecular dynamics - Implications in functional loss and modulation of reactive oxygen species generation by pa
Keywords: پیرووات دهیدروژناز پیچیده; LADH; (dihydro)lipoamide dehydrogenase; PDHc; pyruvate dehydrogenase complex; α-KGDHc; alpha-ketoglutarate dehydrogenase complex; ROS; reactive oxygen species; RMSD; root mean square deviation; FAD; flavin adenine dinucleotide; NAD+/NADH; nicotinamide ad
Synthesis and antifungal activity of 5-iodo-1,4-disubstituted-1,2,3-triazole derivatives as pyruvate dehydrogenase complex E1 inhibitors
Keywords: پیرووات دهیدروژناز پیچیده; 5-Iodo-1,4-disubstituted-1,2,3-triazole; Pyruvate dehydrogenase complex; Inhibitor; Antifungal activity;