Keywords: پروتئین کیناز وابسته به Rho; TSLP; Thymic stromal lymphopoietin; LXR; Liver X receptor; RXR; retinoid X receptor; RAR; retinoic acid receptor; PPAR; peroxisome proliferator-activated receptor; VDR; vitamin D receptor; GR; glucocorticoids receptor; 22R-HC; 22(R)-hydroxycholesterol;
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Keywords: پروتئین کیناز وابسته به Rho; A1AT; α1-antitrypsin (A1AT); ALB; albumin; BMP-2; bone morphogenetic protein 2; BSA; bovine serum albumin; DAPI; 4',6-diamidino-2-phenylindole; BMP-4; bone morphogenic protein 4; DE; definitive endoderm; DMEM-HG; Dubelcco's modified Eagle's medium-high
Keywords: پروتئین کیناز وابسته به Rho; 15-PGDH; 15-hydoxyprostaglandin dehydrogenase; AA; arachidonic acid; AF; atrial fibrillation; AKI; acute kidney injury; Akt; alpha serine/threonine-protein kinase; ALA; alpha-linolenic acid; AMD; age-related macular degeneration; Ang II; angiotensin II; B
Keywords: پروتئین کیناز وابسته به Rho; Extracellular matrix; Gradient nanopattern plates; Human endothelial colony-forming cells; Focal adhesion; Rho-associated protein kinase;
Keywords: پروتئین کیناز وابسته به Rho; AAC; abdominal aortic constriction; ADAMS; a disintegrin and metalloproteases; ADAMTS; a distingetrin and metalloproteinase with a thrombospondin domain; Ang II; angiotensin II; BM; basement membrane; BMP-1; bone morphogenic protein-1; CITP; carboxy-termi
Keywords: پروتئین کیناز وابسته به Rho; Di-n-butyl phthalate (DBP); Neuroplasticity; Rho-GTPase; ANOVA; analysis of variance; BBP; benzyl butyl phthalate; CREB; cyclic adenosine monophosphate response element binding protein; DBP; di-n-butyl phthalate; DiBP; diisobutyl phthalate; DEHP; di(2-eth
Keywords: پروتئین کیناز وابسته به Rho; ASC; adult stem Cell; ASN; auditory sensory neurons; Atoh1; protein atonal homolog 1; bFGF; basic fibroblast growth factor; bHLH; basic helix-loop-helix; BDNF; brain-derived neurotrophic factor; BMP4; bone morphogenetic protein 4; CDK; cyclin-dependent ki
Keywords: پروتئین کیناز وابسته به Rho; APC; allophycocyanin; BBB; blood brain barrier; DAPI; 4â²,6-diamidino-2-phenylindole; EMPs; endothelial microparticles; FITC; fluorescein isothiocyanate; ICAM-1; intercellular cell adhesion molecule; LDH; lactate dehydrogenase; LRP; lipoprotein receptor-
Keywords: پروتئین کیناز وابسته به Rho; Cancer stem-like cells; Mevalonate cascade; Ras; Rho; Stemness; Statins; Yap; ACAT; acetoacetyl-CoA transferase; acetyl-CoA; acetyl-coenzyme A; Arp2/3; actin-related protein 2/3 (actin polymerizing complex); BPs; bisphosphonates; CAMs; cell adhesion molec
Keywords: پروتئین کیناز وابسته به Rho; 3D; 3-dimesional; BMP; bone morphogenetic protein; ECM; extracellular matrix; FN; fibronectin; LN; laminin; MLC; myosin light chain; MSC; mesenchymal stem cell; PAAm; polyarylamide; PDMS; polydimethylsiloxane; PEG; polyethylene glycol; Rock; Rho-associate
Keywords: پروتئین کیناز وابسته به Rho; ADAMTS1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; ATP; adenosine triphosphate; APP; amyloid beta precursor protein; ANGPT2; angiopoietin 2; Ara-C; arabinosylcytosine; GBA; beta-glucocerebrosidase; BDNF; brain derived neurotrophic factor;
Fasudil inhibits neutrophil-endothelial cell interactions by regulating the expressions of GRP78 and BMPR2
Keywords: پروتئین کیناز وابسته به Rho; Rho-associated protein kinase; Neutrophil-endothelial cell interaction; Glucose-regulated protein 78; Bone morphogenic protein receptor 2;
Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine
Keywords: پروتئین کیناز وابسته به Rho; Mouse Model; Type 2 Diabetes; Enteroendocrine Cells; Signal Transduction; CCK; cholecystokinin; Ctgf; connective tissue growth factor; Cyr61; cysteine-rich angiogenic inducer 61; Dll1; delta-like protein 1; DBZ; dibenzazepine; EdU; 5-ethynyl-2â²-deoxyuri
Layilin is critical for mediating hyaluronan 35Â kDa-induced intestinal epithelial tight junction protein ZO-1 in vitro and in vivo
Keywords: پروتئین کیناز وابسته به Rho; HA35; hyaluronan 35Â kDa; ZO-1; zonula occludens-1; TLR; toll-like receptor; DSS; dextran sulfate sodium; IBD; inflammatory bowel disease; JAM; junctional adhesion molecule; ROS; reactive oxygen species; RHAMM; receptor for HA mediated motility; HARE; HA
Targeting the NRF-2/RHOA/ROCK signaling pathway with a novel aziridonin, YD0514, to suppress breast cancer progression and lung metastasis
Keywords: پروتئین کیناز وابسته به Rho; YD0514; Aziridonin; Breast cancer; Metastasis; NRF-2/RHOA/ROCK pathway; Oridonin; BSA; bovine serum albumin; CFL; cofilin; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EMT; epithelial-mesenchymal transition; ER; estrogen receptor; F
AGC kinases, mechanisms of regulation âand innovative drug development
Keywords: پروتئین کیناز وابسته به Rho; AGC kinase; group of kinases related to PKA PKG and PKC; PKA; protein kinase A; PKC; protein kinase C; PKG; protein kinase G; PRK; protein kinase C related kinase (also termed PKN protein kinase N); PDK1; 3-phosphoinositide-dependent protein kinase 1; PKB
Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity
Keywords: پروتئین کیناز وابسته به Rho; Vascular smooth muscle; Vasoproliferative disease; Vascular smooth muscle cell; Phenotype switching; Signalling pathways; AJ; adherens junction; ApoE; apolipoprotein E; BMP; bone morphogenetic protein; CAD; coronary artery diseases; CADASIL; cerebral auto
Label-free cell signaling pathway deconvolution of angiotensin type 1 receptor reveals time-resolved G-protein activity and distinct AngII and AngIIIIV responses
Keywords: پروتئین کیناز وابسته به Rho; AngII; Angiotensin II; AT1R; angiotensin type 1 receptor; βarr; β-Arrestin; DMR; dynamic mass redistribution; ERK; extracellular signal-regulated kinase; GPCR; G protein coupled receptor; PTX; pertussis toxin; PI3K; phosphoinoside 3-kinase; rVSMC; rat v
Pentanoic acid induces thymic stromal lymphopoietin production through Gq/11 and Rho-associated protein kinase signaling pathway in keratinocytes
Keywords: پروتئین کیناز وابسته به Rho; TSLP; thymic stromal lymphopoietin; FA; fatty acid; FFA; free fatty acid; SCFA; short-chain free fatty acid; FFAR; free fatty acid receptor; GPCR; G protein-coupled receptor; ROCK; Rho-associated protein kinase; TPA; 12-O-tetradecanoylphorbol-13-acetate;
Stretch-induced actomyosin contraction in epithelial tubes: Mechanotransduction pathways for tubular homeostasis
Keywords: پروتئین کیناز وابسته به Rho; ATP; adenosine triphosphate; DAG; diacylglycerol; ECM; extracellular matrix; FAK; focal adhesion kinase; GAP; GTPase activating protein; GDI; guanine dissociation factor; GEF; guanine nucleotide exchange factor; GPCR; G protein coupled receptor; HUVEC; Hu
The protein serine/threonine phosphatases PP2A, PP1 and calcineurin: A triple threat in the regulation of the neuronal cytoskeleton
Keywords: پروتئین کیناز وابسته به Rho; AD; Alzheimer disease; CaM; calmodulin; CNA/B; calcineurin A/B subunit; Glu-MTs; detyrosinated microtubules; GSK3β; glycogen synthase kinase 3β; MAP; microtubule-associated protein; MARCKS; myristoylated alanine-rich C-kinase substrate; MT; microtubule;
Effect of N-arachidonoyl-l-serine on human cerebromicrovascular endothelium
Keywords: پروتئین کیناز وابسته به Rho; 2-AG; 2-Arachidonoylglycerol; ARA-S; N-arachidonoyl-l-serine; CB1 receptor; cannabinoid receptor 1; CB2 receptor; cannabinoid receptor 2; e-NOS; endothelial nitric oxide synthetase; Erk1/2; extracellular signal-regulated kinases 1and 2; ET-1; Endothelin 1
12(S)-HETE increases intracellular Ca2+ in lymph-endothelial cells disrupting their barrier function in vitro; stabilization by clinical drugs impairing calcium supply
Keywords: پروتئین کیناز وابسته به Rho; 12(S)-HETE; Intracellular Ca2+; PLC/IP3; MYLK; MLC2; Endothelial integrity disruption; Ser19; serine 19; MLC2; myosin light chain 2; CCID; circular chemorepellent induced defect; MYLK; (nonmuscular) myosin light chain kinase; IP3; inositol trisphosphate;
Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement
Keywords: پروتئین کیناز وابسته به Rho; Cytokine; IL-6; Cancer stem cell; Chemoresistance and EMT; MAPK; mitogen-activated protein kinases; STAT3; signal transducer and activator of transcription 3; gp130; glycoprotein 130; C/EBP; CCAAT/enhancer-binding protein; JAK; Janus kinase; PI3K; phospho
Citron Rho-interacting kinase mediates arsenite-induced decrease in endothelial nitric oxide synthase activity by increasing phosphorylation at threonine 497: Mechanism underlying arsenite-induced vascular dysfunction
Keywords: پروتئین کیناز وابسته به Rho; EC; endothelial cells; ROS; reactive oxygen species; NO; nitric oxide; eNOS; endothelial NO synthase; PP1; protein phosphatase 1; AMPK; AMP-activated protein kinase; PKC; protein kinase C; PP2A; protein phosphatase 2A; CRIK; citron Rho-interacting kinase;
Autophagy in the eye: Development, degeneration, and aging
Keywords: پروتئین کیناز وابسته به Rho; Autophagy; Retina; Chaperone mediated autophagy; Lysosomes; Mitophagy; Retinal ganglion cells; Retinal pigment epithelial cells; Photoreceptor; Glaucoma; Macular degeneration; Retinal dystrophies; Diabetic retinopathy; 3-MA; 3-methyl adenine; 8-OH DPAT; 8
A real-time, fluorescence-based assay for Rho-associated protein kinase activity
Keywords: پروتئین کیناز وابسته به Rho; Kinase activity assay; Fluorescence-based biosensor; Rho-associated protein kinase; Inhibition; Small molecule screeningROCK, rho-associated protein kinase; HCC, hepatocellular carcinoma; HTS, high-throughput screening; CHEF, chelation-enhanced fluorescen
Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway
Keywords: پروتئین کیناز وابسته به Rho; Sep15; 15-kDa selenoprotein; ROCK; Rho-associated protein kinase; MLC; myosin light chain; MYPT; myosin phosphatase targeting protein; Sec; selenocysteine; SECIS; sec insertion sequence; Dox; doxycycline; 15-kDa selenoprotein; Membrane blebbing; Apoptosis
Elongation factor-1A1 is a novel substrate of the protein phosphatase 1-TIMAP complex
Keywords: پروتئین کیناز وابسته به Rho; BPAEC; bovine pulmonary artery endothelial cell; EC; endothelial cell; ECIS; electric cell-substrate impedance sensing; eEF1A1; elongation factor 1A1; ERM; ezrin-radixin-moesin; GST; glutathione S-transferase; HPAEC; human pulmonary artery endothelial cel
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo
Keywords: پروتئین کیناز وابسته به Rho; 6-OHDA; 6-hydroxydopamine; AAV; adeno-associated viral vector; Bcl-2; B-cell lymphoma 2; CNS; central nervous system; ctl; contralateral; DAPI; 4â²,6-diamidino-2-phenylindole; DIV; day in vitro; DOPAC; 3,4-dihydroxyphenylacetic acid; EGFP; enhanced green
The formation of cortical actin arrays in human trabecular meshwork cells in response to cytoskeletal disruption
Keywords: پروتئین کیناز وابسته به Rho; Trabecular Meshwork; Cytoskeleton; Actin; Rho-associated protein kinase; Latrunculin B
ROCK inhibitor Y-27632 prevents porcine oocyte maturation
Keywords: پروتئین کیناز وابسته به Rho; Y-27632; Rho-associated protein kinase; Actin; Oocyte maturation; Spindle migration;
Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple sclerosis
Keywords: پروتئین کیناز وابسته به Rho; Sphingosine-1-phosphate; B cells; migration; autoimmunity; circulation; fingolimod; FTY720; primary immunodeficiencies; ALL; Acute lymphoblastic leukemia; B-CLL; B-cell chronic lymphocytic leukemia; BCR; B-cell receptor; BFP; Blue fluorescent protein; BTK
Rho-associated protein kinase isoforms stimulate proliferation of vascular smooth muscle cells through ERK and induction of cyclin D1 and PCNA
Keywords: پروتئین کیناز وابسته به Rho; Rho-associated protein kinase; Platelet-derived growth factor; Vascular smooth muscle cell; Cyclin D1; Proliferating cell nuclear antigen; Extracellular signal-regulated kinase
Protein kinase A-mediated phosphorylation of RhoA on serine 188 triggers the rapid induction of a neuroendocrine-like phenotype in prostate cancer epithelial cells
Keywords: پروتئین کیناز وابسته به Rho; PCa; prostate cancer; cAMP; cyclic AMP; NE; neuroendocrine; PSA; prostate-specific antigen; PKA; cAMP-dependent protein kinase; bFGF; basic fibroblast growth factor; NGF; nerve growth factor; 6-Bnz-cAMP; N6-benzoyl-cAMP; Fsk; forskolin; C3T; cell-permeabl
The hallmarks of CDKN1C (p57, KIP2) in cancer
Keywords: پروتئین کیناز وابسته به Rho; AML; acute myeloid leukemia; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-x long; BCR-ABL; breakpoint cluster region-V-abl Abelson murine leukemia viral oncogene homolog 1; bHLH; basic helix-loop-helix; BWS; Beckwith-Wiedemann Syndrome; CDK; cy
Characterizations of sphingosylphosphorylcholine-induced scratching responses in ICR mice using naltrexon, capsaicin, ketotifen and Y-27632
Keywords: پروتئین کیناز وابسته به Rho; SPC [sphingosylphosphorylcholine]; Itch; Scratching; d-erythro SPC; Rho-associated protein kinase
Alzheimer's disease: Channeling APP to non-amyloidogenic processing
Keywords: پروتئین کیناز وابسته به Rho; Alzheimer's disease; β-Amyloid; Non-steroidal anti-inflammatory drugs; Rho; Rho-associated protein kinase; Statins;