Keywords: Fog; Folded gastrulation; TF; transcription factor; GPCR; G-protein coupled receptor; Mist; mesoderm invagination signal transducer; Cta; Concertina; RhoGEF; Rho guanine nucleotide exchange factor; Rok; Rho kinase; PMG; posterior midgut; GBE; germ band ex
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Direct regulation of p190RhoGEF by activated Rho and Rac GTPases
Keywords: RhoGEF; Rho guanine nucleotide exchange factors; RhoGAP; GTPase-activating proteins; DH; Dbl homology; PH; pleckstrin homology; PRG; PDZRhoGEF; TEV; Tobacco Etch Virus; His6; hexahistidine peptide; GST; glutathione S-transferase; ITC; isothermal titration
Heterotrimeric G protein Gαs subunit attenuates PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, by direct interaction
Keywords: PKA; protein kinase A; RhoGEF; Rho-specific guanine nucleotide exchange factor; Rho; Rho family small GTP-binding proteins; SRE; serum response element; CRE; cAMP response element; RhoGEF; Gαs/olf; Interaction; Gene transcription;
Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (LARG) by Cdk1
Keywords: LARG; leukemia-associated Rho guanine nucleotide exchange factor; GTP; guanine-nucleotide triphosphate; GEF; guanine-nucleotide exchange factor; RhoGEF; Rho guanine-nucleotide exchange factor; Cdk1; cyclin-dependent kinase; pNull; phosphonull; pMim; phosp
Diverse roles of LPA signaling in the intestinal epithelium
Keywords: LPA; lysophosphatidic acid; IEC; intestinal epithelial cell; IBD; inflammatory bowel disease; CRC; colorectal cancer; PA; phosphatidic acid; PLA; phospholipase A; ATX; autotaxin; YAMC; young adult mouse colonic epithelium; MSIE; mouse small intestinal epi
Endothelial RhoGEFs: A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells
Keywords: RhoGEF; Rho GTPases; Rac; Cdc42; VEGF; Endothelial cell cytoskeleton; Tumor angiogenesis;
Controlling the switches: Rho GTPase regulation during animal cell mitosis
Keywords: Rho GTPase; RhoGEF; RhoGAP; Mitosis; Cytokinesis;
Identification of a Rho family specific guanine nucleotide exchange factor, FLJ00018, as a novel actin-binding protein
Keywords: G protein; guanosine triphosphate binding protein; Rho; Rho family small GTPase; GEF; guanine-nucleotide exchange factor; RhoGEF; Rho specific GEF; GPCR; heterotrimeric G protein coupled receptor; PBS; phosphate-buffered saline; FLJ00018; Actin; G protein
Reduced cell number in the hindgut epithelium disrupts hindgut left-right asymmetry in a mutant of pebble, encoding a RhoGEF, in Drosophila embryos
Keywords: Left-right asymmetry; RhoGEF; Pebble; Gut development; Drosophila;
The RAC specific guanine nucleotide exchange factor Asef functions downstream from TEL-AML1 to promote leukaemic transformation
Keywords: TEL-AML1; ASEF; Acute lymphoblastic leukaemia; ALL; RhoGEF; ARHGEF4
Mechanical stretch-induced RhoA activation is mediated by the RhoGEF Vav2 in mesangial cells
Keywords: RhoA; Mechanical stress; Mesangial cell; Vav2; RhoGEF; Glomerulosclerosis; Epidermal growth factor receptor;
Loss of Lsc/p115 Protein Leads to Neuronal Hypoplasia in the Esophagus and an Achalasia-Like Phenotype in Mice
Keywords: Lsc/p115; Achalasia; Esophageal Manometry; ChAT; choline acetyl transferase; GDP; guanosine diphosphate; GFAP; glial fibrillary acidic protein; GTP; guanosine triphosphate; LES; low esophageal sphincter; NGF; nerve growth factor; nNOS; neuronal nitric oxi
Targeted deletion of the zebrafish obscurin A RhoGEF domain affects heart, skeletal muscle and brain development
Keywords: Obscurin; RhoGEF; Cellular differentiation; Cardiac development; Retina;
Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis
Keywords: Bone mineral density; RhoGTPase; RhoGEF; Osteoporotic; Elderly women;
An expression screen for RhoGEF genes involved in C. elegans gonadogenesis
Keywords: C. elegans; Gonadogenesis; RhoGEF; Morphogenesis; Organogenesis; Anchor cell invasion; Gonad development; Rho GTPase; Rho; Rac; cdc42; Mig-2; Ced-10; cdc-42; Rho-1
A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells
Keywords: Gα13; RhoGEF; Lbc; Pleckstrin homology domain; Actin stress fibers; Membrane recruitment
G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 NFκB serine 536 phosphorylation in human keratinocytes
Keywords: PAR-2; proteinase-activated receptor-2; PAR-2 AP; PAR-2 activating peptide; 2f-LIGKV-OH; 2-furoyl-LIGKV-hydroxyl; NFκB; nuclear factor kappa B; IKK; inhibitory kappa B kinase; PKC; protein kinase C; siRNA; small interfering ribonucleic acid; RNAi; ribonu
18 Wheeler regulates apical constriction of salivary gland cells via the Rho-GTPase-signaling pathway
Keywords: 18 Wheeler; Rho GTPase; RhoGEF; RhoGAP; Drosophila; Invagination; Salivary gland; Tubulogenesis
Reduced mRNA and Protein Content of Rho Guanine Nucleotide Exchange Factor (RhoGEF) in Bartter's and Gitelman's Syndromes: Relevance for the Pathophysiology of Hypertension
Keywords: RhoA; Rho-kinase; RhoGEF; Bartter's syndrome; Gitelman's syndrome; hypertension;