Keywords: ATG; autophagy-related proteins; CMA; chaperone-mediated autophagy; ULK1; Unc-51-like kinase 1; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; PE; phosphatidylethanolamine; IFN-γ; interferon-γ; IL-1; interleukin-1; IL-17; inte
مقالات ISI (ترجمه نشده)
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Keywords: PRR; pattern recognition receptor; PAMP; pathogen-associated molecular pattern; DAMP; danger-associated molecular pattern; NLRP3; NOD-, LRR- and pyrin domain-containing 3; TLR; toll-like receptor; CLR; C-type lectin receptor; NLR; NOD-like receptor; RIG-I
Keywords: AP-1; activator protein-1; ATP; adenosine triphosphate; BDNF; brain-derived neurotrophic factor; CCI; chronic constriction injury; CCL2; chemokine C-C motif ligand 2; CCL21; chemokine C-C motif ligand 21; CD11b; cluster of differentiation 11b; CD14; clust
Keywords: CARD; caspase recruitment domain; CC; coiled coil; DAMP; danger-associated molecular pattern; DD; death domain; DED; death effector domain; NBD; nucleotide-binding domain; NLR; nucleotide binding and oligomerization domain (NOD) leucine-rich repeat (LRR)-
Keywords: AD; atopic dermatitis; AMP; antimicrobial peptide; CAPS; cryopyrin-associated periodic syndrome; CPA; carboxypeptidase A; CTMC; connective tissue mast cell; dsRNA; double-stranded RNA; GF; germ-free; HSV; herpes simplex virus; Ig; immunoglobulin; IL; inte
Keywords: Liver; Immunity; Tolerance; Autoimmunity; Antigen presentation; Innate lymphocytes; AIH; autoimmune hepatitis; ALD; autoimmune liver disease; APC; antigen-presenting cell; CTLA-4; cytotoxic T cell antigen-4; DC; dendritic cell; α-GC; α-galactosylceramid
Keywords: Clarithromycin (PubChem CID: 84029); poly I:C (PubChem CID: 32744); Pam3CSK4 (PubChem CID: 130704); CAM; clarithromycin; CARD; caspase activation and recruitment domain; CCL5; chemokine (C-C motif) ligand 5; CF; cystic fibrosis; COPD; chronic obstructive
Keywords: Live vaccines; Adenoviruses; Encapsulation; M-like cells; Adjuvants; Zebrafish; TLR; Toll-like receptor; NLR; NOD-like receptor; RLR; RIG-like receptor;
Keywords: ACP5; Acid phosphatase 5; ADAR1; Adenosine deaminase RNA-specific 1; AGS; Aicardi-Goutières syndrome; ALRs; AIM2-like receptors; AIM2; Absent in melanoma 2; ASC; Apoptosis-associated speck-like protein containing a CARD; CANDLE; Chronic atypical neutroph
Keywords: CARD; caspase recruitment domain; CLR; C-type lectin receptor; DC; dendritic cells; EAE; experimental autoimmune encephalitis; EAU; experimental autoimmune uveoretinitis; HEL; hen egg lysozyme; IRBP; interphotoreceptor retinal binding protein; MR; macroph
Keywords: BabA; blood-group antigen binding adhesion A; CagA; cytotoxin-associated antigen A; cagPAI; cag pathogenicity island; CD74; HLA II-associated invariant chain; CLR; C-type lectin receptor; IL; interleukin; FUT4; fucosyltransferase 4; HLA II; human leukocyt
Keywords: LR; Logistic Regression; rLR; robust Logistic Regression; KLR; Kernel Logistic Regression; rKLR; robust Kernel Logistic Regression; rMKLR; robust Multiple Kernel Logistic Regression; Classification; Label noise; Model selection; Multiple Kernel Learning;
Strategies of supplemental irrigation and modified planting densities to improve the root growth and lodging resistance of maize (Zea mays L.) under the ridge-furrow rainfall harvesting system
Keywords: RFRH; ridge-furrow rainfall harvesting system; RLD; root length density; RSD; root surface area density; RLR; root lodging rate; SLR; stalk lodging rate; TLR; total lodging rate; RSR; root shoot ratio; SDM; shoot dry matter; SD; stem diameter; PH; plant h
The role of type I interferons in innate and adaptive immunity against viruses in Atlantic salmon
Keywords: Adjuvant; DNA vaccine; Fish; IFN; ISG; TLR; CRFB; class II cytokine receptor family member; HE; hemagglutininesterase; IFN; interferon; IFN-I; type I IFN; IFNAR; mammalian type I IFN receptor; IPNV; infectious pancreatic necrosis virus; IPS-1; interferon
Hepatitis B Virus Does Not Interfere With Innate Immune Responses in the Human Liver
Keywords: PRR; Virus Immune Evasion; PAMP; Ex Vivo; CHB; chronic hepatitis B; CTRL; uninfected control; dsRNA; double-stranded RNA; HBcAg; HBV core protein; HBeAg; hepatitis B e antigen; HBsAg; HBV surface protein; HBV; hepatitis B virus; IFN; interferon; ISG; in
Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases
Keywords: ALS; amyotrophiclateral sclerosis; AP-1; activator protein 1; APC; antigen-presenting cell; APC/C; anaphase promoting complex/cyclosome; CLR; C-type lectin receptor; CRL; Cullin RING ligase; ERK; extracellular signalregulated kinase; FANC; Fanconi anemia
Regulation and biological roles of the multifaceted miRNA-23b (MIR23B)
Keywords: miRNAs; MicroRNAs; C9orf3; Chromosome 9 Open Reading Frame 3; pri-miRNAs; primary miRNA; pre-miRNAs; precursor miRNAs; miRISC; miRNA-induced silencing complex; ECs; endothelial cells; VSMCs; vascular smooth muscle cells; ACTA2; smooth muscle α-actin; MYH
MicroRNA regulation of Toll-like receptor signaling pathways in teleost fish
Keywords: MicroRNA; Toll-like receptors; Fish; Immune response; AP-1; activator protein; CCR3; CC chemokine receptor 3; CDS; coding region; COX2; cyclooxygenase-2 enzyme; CQ; chloroquine; ER; endoplasmic reticulum; Flg 22; amino-terminal fragment of flagellin; GCRV
Molecular characterisation, ontogeny and expression analysis of melanoma differentiation-associated factor 5 (MDA5) from Asian seabass, Lates calcarifer
Keywords: Melanoma differentiation-associated protein 5; MDA5; RLR; PRR; Asian seabass; Lates calcarifer; Bacterial infection; Poly I:C; Gene expression; Ontogeny;
Autoimmunity in multiple sclerosis: role of sphingolipids, invariant NKT cells and other immune elements in control of inflammation and neurodegeneration
Keywords: Ag; antigen; APC; antigen presenting cell; BBB; blood brain barrier; BCR; B cell receptor; BDNF; brain-derived neurotrophic factor; CIS; clinically isolated syndrome; CLR; C-type lectin receptor; CNS; central nervous system; CSF; cerebrospinal fluid; DAMP
Original ArticleRole of cellular metabolism in regulating type I interferon responses: Implications for tumour immunology and treatment
Keywords: Type I interferons; Immunometabolism; Antiviral immune responses; Inflammation; Cancer; IFN; interferon; ISG; interferon stimulated genes; PD-L1; program death-ligand 1; TLR; Toll-like receptor; RIG; retinoic acid-inducible gene-like helicases; RLR; RIG-I
Transflammation: Innate immune signaling in nuclear reprogramming
Keywords: PRR; pattern recognition receptor; TLR; toll-like receptor; RIG-1; retinoid acid-inducible gene I; RLR; RIG-1-like receptor; ROS; reactive oxygen species; RNS; reactive nitrogen species; iPSC; induced pluripotent stem cell; ESC; embryonic stem cell; MHC;
Identification, ontogeny and expression analysis of a novel laboratory of genetics and physiology 2 (LGP2) transcript in Asian seabass, Lates calcarifer
Keywords: Laboratory of genetics and physiology 2; LGP2; RLR; PRR; Asian seabass; Lates calcarifer; Bacterial infection; Poly I:C; Gene expression; Ontogeny;
Zebrafish STAT6 negatively regulates IFNÏ1 production by attenuating the kinase activity of TANK-binding kinase 1
Keywords: STAT6; Negative regulator; Interferon; TBK1; Zebrafish; CIP; calf intestinal phosphatase; CPE; cytopathic effect; EPC; epithelioma papulosum cyprini; GAS; interferon gamma activated sequence; IFN; interferon; IRF; IFN regulatory factor; IRF3; interferon r
Regulation of type I interferon responses by mitochondria-derived reactive oxygen species in plasmacytoid dendritic cells
Keywords: 7-AAD; 7-aminoactinomycin-D; AMA; Antimycin-A; IFN; interferon; IRF; interferon regulatory factor; MAVS; mitochondrial antiviral-signaling; mtROS; mitochondrial reactive oxygen species; pDCs; plasmacytoid dendritic cells; PI3K; phosphatidylinositol-3-kina
The miiuy croaker microRNA transcriptome and microRNA regulation of RIG-I like receptor signaling pathway after poly(I:C) stimulation
Keywords: microRNA; Transcriptome; Miiuy croaker; RLR; Signaling pathway
NOD2 in zebrafish functions in antibacterial and also antiviral responses via NF-κB, and also MDA5, RIG-I and MAVS
Keywords: Nod-like receptor; NOD2; RLR; NF-kappaB; ZebrafishNOD, nucleotide oligomerization domain; NF-κB, nuclear transcription factor-κB; MDA5, melanoma differentiation-associated gene 5; RIG-I, retinoic acid-inducible gene I; MAVS, mitochondrial antiviral signal
Rupestonic acid derivative YZH-106 suppresses influenza virus replication by activation of heme oxygenase-1-mediated interferon response
Keywords: IAV; influenza A virus; HO-1; heme oxygenase-1; Nrf2; erythroid 2-related factor 2; ISGs; IFN-stimulated genes; RdRp; RNA-dependent RNA polymerase; TLRs; toll-like receptors; RLR; RIG-I-like receptors; MKP5; MAPK phosphatase 5; IRF3; interferon regulatory
Testicular immunoregulation and spermatogenesis
Keywords: BTB; blood-testis barrier; EAO; experimental autoimmune orchitis; Gas6; growth arrest-specific gene 6; IRF3; interferon regulatory factor 3; IPS-1; IFN-β; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinases; MDA5; melanoma differentiation-
Serum cytokine profiles of patients with interstitial lung disease associated with anti-CADM-140/MDA5 antibody positive amyopathic dermatomyositis
Keywords: Dermatomyositis; Interstitial lung disease; Cytokine; Chemokine CX3CL1; Ab; antibody; ADM; amyopathic dermatomyositis; CT; computed tomography; CX3CL1; chemokine (C-X3-C motif) ligand 1; EGF; epidermal growth factor; FGF-2; fibroblast growth factors-2; Fl
Mode of dendritic cell activation: The decisive hand in Th2/Th17 cell differentiation. Implications in asthma severity?
Keywords: Asthma; Dendritic cells; T helper 2 cells; T helper 17 cells; Eosinophils; Neutrophils; Ag; antigen; AHR; airway hyper responsiveness; APC; antigen presenting cell; ATS; American Thoracic Society; BAL; bronchoalveolar lavage; Bcl-6; B-cell lymphoma; C; co
Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7
Keywords: MAVS variants; Negative regulator; Interferon; IRF7; Zebrafish; CARD; caspase recruiting domain; CPE; cytopathic effect; DBD; DNA binding domain; EPC; epithelioma papulosum cyprini; GBP4; guanylate binding protein 4; IFN; interferon; IKKε; IkappaB kinase
Research ArticleExpression and functionality of Toll- and RIG-like receptors in HepaRG cells
Keywords: PHH; primary human hepatocyte; TLR; toll-like receptor; RIG-I; retinoic acid-inducible gene 1; RLR; RIG-like receptor; RT; reverse transcription; qPCR; quantitative polymerase chain reaction; FACS; fluorescence-activated cell sorting; IL-6; interleukin-6;
Research ArticleControl of temporal activation of hepatitis C virus-induced interferon response by domain 2 of nonstructural protein 5A
Keywords: HCV; hepatitis C virus; RIG-I; retinoic acid-inducible gene 1; TLR-3; Toll-like receptor 3; RLR; RIG-I like receptor; MDA5; Melanoma Differentiation-Associated protein 5; IFN; interferon; IRF-3; IFN regulatory factor-3; ISG; IFN-induced gene; MAVS; mitoch
Integration of PKR-dependent translation inhibition with innate immunity is required for a coordinated anti-viral response
Keywords: Innate immunity; Viral sensing; RLR;
Functional characterization of the evolutionarily preserved mitochondrial antiviral signaling protein (MAVS) from rock bream, Oplegnathus fasciatus
Keywords: Mitochondrial antiviral signaling protein; RLR; PRR; Antiviral; Rock bream;
The emerging role of human PYHIN proteins in innate immunity: Implications for health and disease
Keywords: AIM2; absent in melanoma 2; ALR; AIM2-like receptor; ASC; apoptosis-associated speck-like protein containing a CARD; CARD; caspase activation and recruitment domain; cGAMP; cyclic GMP-AMP; cGAS; cGAMP synthase; DAI; DNA-dependent activator of IFN-regulato
ReviewThe role of Kupffer cells in hepatitis B and hepatitis C virus infections
Keywords: HBV; Hepatitis B virus; HCV; Hepatitis C virus; KC; Kupffer cells; NK cells; natural killer cells; PRR; pattern recognition receptor; TLR; Toll-like receptor; RLR; RIG-like receptor; NLR; NOD-like receptor; CLR; C-type lectins; SR; Scavenger receptor; ROS
Human DExD/H RNA helicases: Emerging roles in stress survival regulation
Keywords: 5â²ppp; 5â² triphosphate; AMD; ARE-mediated mRNA decay; ARE; AU-rich element; ARE-BP; ARE-binding protein; CARD; caspase activation and recruitment domain; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; CDN; cyclic dinucleotide; CRM1; Chromosome Maint
A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane using bioluminescence resonance energy transfer
Keywords: BiFC; bimolecular fluorescence complementation; BRET; bioluminescence resonance energy transfer; CARD; caspase activation and recruitment domain; HCV; hepatitis C virus; HEK; human embryonic kidney; HR1; 4,3 hydrophobic heptad repeat region 1; IFN-β; int
Impaired TLR2 and TLR7 response in olive flounder infected with viral haemorrhagic septicaemia virus at host susceptible 15 °C but high at non-susceptible 20 °C
Keywords: Viral haemorrhagic septicaemia virus (VHSV); TLR; RLR; Interleukin; IFN stimulated genes
Human Type 2 Myeloid Dendritic Cells Produce Interferon-λ and Amplify Interferon-α in Response to Hepatitis C Virus Infection
Keywords: IL-28B SNP; NK Cells; NKT Cells; Viral Immune Regulation; BDCA; blood DC antigen; CpG; cytosine-phosphate-guanosine; CXCL; CXC-chemokine ligand; DC; dendritic cell; dsRNA; double-strand RNA; HCV; hepatitis C virus; HCVcc; cell culture-derived hepatitis
Update on the role of innate immune receptors during Brucella abortus infection
Keywords: TLR; Toll-like receptors; NLR; cytosolic nucleotide binding and oligomerization domain-like receptors; RLR; retinoic acid-inducible gene 1 (RIG-I)-like receptors; MDA5; melanoma differentiation associated gene 5; LGP2; laboratory of genetics and physiolog
Transcriptional regulation of type I interferon gene expression by interferon regulatory factor-3 in Japanese flounder, Paralichthys olivaceus
Keywords: ATF2; activating transcription factor 2; BAC; bacterial artificial clone; CpG-ODN; cytosine-phosphate-guanosine oligodeoxynucleotides; dsRNA; double-strand RNA; IFN; interferon; IKKε; IκB kinase epsilon; IPS-1/MAVS/VISA/Cardif; IFN-β promoter stimulato
Toll-like receptors and macrophage activation in atherosclerosis
Keywords: TLR; Toll-like receptor; PAMP; Pathogen associated molecular pattern; LDL; Low density lipoprotein; SMC; Smooth muscle cell; VCAM-1; Vascular cell adhesion molecule-1; M-CSF; Macrophage colony stimulating factor; TCFA; Thin-cap fibroatheroma; MMP; Matrix
Avian-specific TLRs and downstream effector responses to CpG-induction in chicken macrophages
Keywords: LPS; lipopolysaccharide; TLR; toll-like receptor; MyD88; myeloid differentiation primary response gene 88; ODN; oligonucleotide; NLR; nod-like receptor; PRR; pattern recognition receptor; PAMP; pathogen associated molecular patterns; RLR; RIG-I like recep
Targeted antigen delivery and activation of dendritic cells in vivo: Steps towards cost effective vaccines
Keywords: APC; antigen presenting cell; cDC; conventional dendritic cell; CLR; C type lectin receptor; DC; dendritic cell; FcR; Fc receptor; IFN; interferon; LC; Langerhans cell; MPL; monophosphoryl lipid A; MR; mannose receptor; NLR; NOD-like receptor; NLRP3; NLR
TLRs, NLRs and RLRs: Innate sensors and their impact on allergic diseases - A current view
Keywords: TLR; NLR; RLR; Innate immunity; Allergy; Asthma;
Molecular cloning and immune responsive expression of MDA5 gene, a pivotal member of the RLR gene family from grass carp Ctenopharyngodon idella
Keywords: Grass carp (Ctenopharyngodon idella); MDA5; RLR; Gene cloning; mRNA expression; Grass carp reovirus