TLRs, NLRs and RLRs: Innate sensors and their impact on allergic diseases - A current view

► TLRs, NLRs, and RLRs are major innate immune pattern recognition receptor families. ► TLRs are cell-surface and intracellular located transmembrane receptors. ► NLRs are cytosolic receptors and also involved in inflammasome formation. ► RLRs are cytosolic receptors for viral RNA and DNA. ► These receptors are crucially involved in the pathogenesis of asthma and allergy.