دانلود مقالات ISI درباره Rnase H + ترجمه فارسی

نسخه های معکوس ویروسی

Viral reverse transcriptases

Keywords: AIDS; acquired immune deficiency syndrome; ALV; avian leukosis virus; AMV; avian myeloblastosis virus; APOBEC; apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like; ASLV; avian sarcoma leukosis virus; AZT; 3′ -azido-3′ -deoxythymidine; BIV;

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2017 سفارش ترجمه

افزونگی در تعمیر ریبونوکلئوتید: رقابت، جبران و همکاری

Redundancy in ribonucleotide excision repair: Competition, compensation, and cooperation

Keywords: nt; nucleotide; dNTP; deoxyribonucleoside triphosphate; rNTP; ribonucleoside triphosphate; pol; DNA polymerase; RNase H; ribonuclease H; Top1; topoisomerase 1; Fen1; flap endonuclease 1; PCNA; proliferating cell nuclear antigen; Exo1; exonuclease 1; Cho;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

جهش در ویروس نقص ایمنی بدن نوع 1 معکوس نسخه برداری که آن را به تجزیه با پروتئاز ویروسی در ویروس حساس در بیماران انتخاب شده

Mutations in human immunodeficiency virus type 1 reverse transcriptase that make it sensitive to degradation by the viral protease in virions are selected against in patients

Keywords: HIV; RT; Protease; Temperature sensitive; RNase H; Gag-Pol;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

مطالعه ساختاری و محاسباتی بر ترکیبات مهار کننده برای فعالیت اندونوکلئاز ویروس آنفلوانزا پلی مراز

Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase

Keywords: PAN; polymerase acidic protein N-terminal domain; MD; molecular dynamics; MM/GBSA; molecular mechanics/generalized Born surface area; H5N1; hemagglutinin type 5 and neuraminidase type; M2 protein; matrix protein 2; HIV; human immunodeficiency virus; SBDD;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2015 سفارش ترجمه

تشخیص حساسیت به سیستم ایمنی در مقابل رترو ویروس ها: درگیری بین سنسورهای ذاتی و سازنده های میزبان

Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors

Keywords: AIM2; absent in melanoma 2; AP-1; activating protein-1; APOBEC; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; AZT; azidothymidine; CCCR5; C-C chemokine receptor type 5; CDK1; cyclin-dependent kinase 1; CXCR4; C-X-C chemokine receptor t

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

تشخیص DNA به کمک عملکرد زیستی از طریق فرایند 3 گروه RNase افزایش H یک پروب tRNA زودرس در یک عصاره جوانه گندم

Biofunction-assisted DNA detection through RNase H-enhanced 3′ processing of a premature tRNA probe in a wheat germ extract

Keywords: DNA detection; tRNA processing; RNase H; Cell-free translation; Wheat germ extract

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Label-free and nicking enzyme-assisted fluorescence signal amplification for RNase H determination based on a G-quadruplexe/thioflavin T complex

Keywords: Label-free; RNase H; Nicking enzyme; G-quadruplex; Thioflavin T;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H

Keywords: 3-Hydroxypyrimidine-2,4-dione (HPD); Human immunodeficiency virus (HIV); RNase H; Inhibitors; Structure-activity-relationship (SAR);

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity

Keywords: 3-Hydroxypyrimidine-2,4-dione (HPD); Human immunodeficiency virus (HIV); RNase H; Integrase strand transfer; Inhibitors; Structure-activity-relationship (SAR);

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Pharmacophore requirements for HIV-1 reverse transcriptase inhibitors that selectively “Freeze” the pre-translocated complex during the polymerization catalytic cycle

Keywords: HIV-1; human immunodeficiency virus type 1; RT; reverse transcriptase; PPi; inorganic pyrophosphate; NTP; nucleoside triphosphate; NDP; nucleoside diphosphate; PFA; phosphonoformic acid, foscarnet; RNase H; ribonuclease H; CPHM; [2-(2-(4-chlorophenyl)hydr

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Next generation sequencing elucidates cacao badnavirus diversity and reveals the existence of more than ten viral species

Keywords: CSSV; cacao swollen shoot virus; CSSCDV; cacao swollen shoot CD virus; CSSTAV; cacao swollen shoot Togo A virus; CSSD; cacao swollen shoot disease; PCR; polymerase chain reaction; RT; reverse transcriptase; RNase H; ribonuclease H; ORF; open reading frame

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

A label-free assay for high sensitive detection of RNase based on two near IR fluorescence probes

Keywords: Near IR; Fluorescence probes; RNase A; RNase H; RNA;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase

Keywords: HAART; HIV-1 dual inhibitors; HIV-1 IN; RNase H; 5-hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives; Privileged structure;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Endonuclease controlled aggregation of gold nanoparticles for the ultrasensitive detection of pathogenic bacterial DNA

Keywords: RNAse H; Gold nanoparticles; Aggregation; DNA detection; Endonuclease enzyme;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Sensitive detection of mRNA by using specific cleavage-mediated isothermal exponential amplification reaction

Keywords: mRNA detection; Isothermal exponential amplification; RNase H; IEXPAR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione as an inhibitor scaffold of HIV reverase transcriptase: Impacts of the 3-OH on inhibiting RNase H and polymerase

Keywords: 3-Hydroxypyrimidine-2,4-dione (HPD); Human immunodeficiency virus (HIV); RNase H; Polymerase; Inhibitors;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Recurrent emergence of structural variants of LTR retrotransposon CsRn1 evolving novel expression strategy and their selective expansion in a carcinogenic liver fluke, Clonorchis sinensis

Keywords: DDH; DNA-DNA hybridization; IN; integrase; IRAP; inter-retrotransposon amplified polymorphism; LINE; long interspersed nuclear element; LTR; long terminal repeat; ORF; open reading frame; PR; protease; RH; RNase H; RT; reverse transcriptase; SINE; short

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Structural Foundations of RNA Silencing by Argonaute

Keywords: Argonaute; RNA-induced silencing complex; RNA silencing; microRNA; RISC; RNA-induced silencing complex; miRNAs; microRNAs; siRNAs; small interfering RNAs; RNAi; RNA interference; piRNAs; Piwi-interacting RNAs; RLC; RISC-loading complex; RNase H; ribonucle

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

An end-point method based on graphene oxide for RNase H analysis and inhibitors screening

Keywords: Graphene Oxide; RNase H; Inhibitor screening; HBV;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis of antisense oligonucleotides containing acyclic alkynyl nucleoside analogs and their biophysical and biological properties

Keywords: Acyclic nucleoside; Antisense oligonucleotide; Alkyne; RNase H; Thermal stability; Nuclease resistance;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase

Keywords: Ocimum sanctum; HIV-1; RNase H; Reverse transcriptase; Triterpenes; Ferulic acid derivatives; AIDS; Acquired Immunodeficiency Syndrome; DCM; dichloromethane; DMAP; 4-dimethylaminopyridine; DP; DNA polymerase; DQF-COSY; Double Quantum Filtered-COrrelation

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H

Keywords: N-Hydroxy thienopyrimidine-2,4-diones; Human immunodeficiency virus (HIV); RNase H; Integrase strand transfer; RT-Polymerase; Molecular modeling and crystallography;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase

Keywords: 2-hydroxyisoquinoline-1,3-diones; HIV; RNase H; Reverse transcriptase; Inhibitor;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H

Keywords: HIV; Integrase; Ribonuclease H; RNase H; Diketoacid; Inhibition;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

DNA repair by RNA: Templated, or not templated, that is the question

Keywords: DSB; double-strand break; HR; homologous recombination; NHEJ; non-homologous end joining; cDNA; complementary DNA; RT; reverse transcriptase; Ty; transposon-yeast; LINE-1; Long Intersperse Element-1; dsDNA; double-stranded DNA; AGS; Aicardi-Goutières syn

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Naturally occurring deletion/insertion mutations within HBV whole genome sequences in HBeAg-positive chronic hepatitis B patients are correlated with baseline serum HBsAg and HBeAg levels and might predict a shorter interval to HBeAg loss and seroconversi

Keywords: aa; amino acid; ADV; adefovir dipivoxil; anti-HBe; antibodies to hepatitis B e antigen; BCP; basic core promoter; C; core; CHB; chronic hepatitis B; CP; core promoter; Del/Ins; deletion/insertion; DR; direct repeat; EN; enhancer; S; surface; HBeAg; hepati

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Single substitution in bacteriophage T4 RNase H alters the ratio between its exo- and endonuclease activities

Keywords: Flap endonuclease; RNase H; DNA arrest suppression; Bacteriophage

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase

Keywords: Antiviral agents; HIV-1 RT dual inhibitors; HIV-1; Molecular modelling; RNase H; (3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-onesHIV-1, human immunodeficiency virus type 1; HAART, highly active antiretroviral therapy; R

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Constitutive stable DNA replication in Escherichia coli cells lacking type 1A topoisomerase activity

Keywords: topo; topoisomerase; cSDR; constitutive stable DNA replication; RNase HI; ribonuclease H1; EdU; ethynyl deoxyuridine; R-loop; Topoisomerase; topA; topB; rnhA; RNase H;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability

Keywords: R-loops; Genome instability; Double-strand breaks; G-quadruplex; Topoisomerase; THO/TREX complex; THSC/TREX-2; ASF splicing factor; mRNP biogenesis; RNA processing factors; RNase H; RNA:DNA helicases; Senataxin; Activation-induced deaminase (AID); APOBEC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Determination of the protease cleavage site repertoire-The RNase H but not the RT domain is essential for foamy viral protease activity

Keywords: Foamy virus; Protease; Cleavage sites; RNase H;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Investigating the mechanisms of ribonucleotide excision repair in Escherichia coli

Keywords: pol; DNA polymerase; nt; nucleotide; RER; ribonucleotide excision repair; Top1; topoisomerase 1; Y-family DNA polymerase; Steric gate mutant; Ribonucleotide excision repair; UmuC: spontaneous mutagenesis; RNase H;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Conserved hydrogen bonds and water molecules in MDR HIV-1 protease substrate complexes

Keywords: MDR; multi-drug resistant; HIV; human immunodeficiency virus; WT; wild type; HAART; highly active antiretroviral therapy; PR; protease; MA; matrix; CA; capsid; NC; nucleocapsid; RT; reverse transcriptase; IN; integrase; RH; rNase H; RMSD; root mean square

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Complex between Human RNase HI and the phosphonate-DNA/RNA duplex: Molecular dynamics study

Keywords: RNase H; Antisense oligonucleotides; Argonaute; RNAi; Phosphonate; Molecular dynamics; ACEMD;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

A combined single-molecule FRET and tryptophan fluorescence study of RNase H folding under acidic conditions

Keywords: Protein folding; RNase H; Single molecule fluorescence resonance energy transfer (smFRET); Tryptophan fluorescence; Folding intermediate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

A dual role of divalent metal ions in catalysis and folding of RNase H1 from extreme halophilic archaeon Halobacterium sp. NRC-1

Keywords: RNase H; Halobacterium sp. NRC-1; Salt-dependent folding; Divalent metal ions; N-terminal domainRNase H, ribonuclease H; Halo-RNH1, RNase H1 from Halobacterium sp. NRC-1; Halo-NTD, N-terminal domain (residues 1–68) of Halo-RNH1; Halo-CTD, C-terminal domai

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Crystal structures of the reverse transcriptase-associated ribonuclease H domain of xenotropic murine leukemia-virus related virus

Keywords: XMRV; Retrovirus; RNase H; Crystal structure; Enzyme inhibition

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach

Keywords: HIV; Molecular fingerprints; Pharmacophore; RNase H; Shape; Virtual screeningBNMB, (Z)-4-(tert-butyl)-N′–((2-methoxynaphthalen-1-yl)methylene)benzohydrazide; LBVS, ligand based virtual screening; DDDP, DNA-dependent DNA polymerase; DHBNH, dihydroxy benzoy

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Primary HIV-1 drug resistance in the C-terminal domains of viral reverse transcriptase among drug-naïve patients from Southern Brazil

Keywords: Primary resistance; Drug resistance mutation; C-terminal; Connection; RNase H; Brazil;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

The effects of RNase H inhibitors and nevirapine on the susceptibility of HIV-1 to AZT and 3TC

Keywords: HIV-1; Reverse transcriptase; NNRTI; RNase H; RNase H Inhibitor (RNHI); AZT resistance

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Small molecule inhibitors of HIV RT Ribonuclease H

Keywords: HIV; RT; RNase H; Antiviral

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Site-specific cleavage of the 40S ribosomal subunit reveals eukaryote-specific ribosomal protein S28 in the subunit head

Keywords: Human 40S ribosomal subunit; MALDI-TOF mass-spectrometry; 18S rRNA; RNase H; Eukaryotic ribosome structure; Human ribosomal protein S28SDS–PAGE, polyacrylamide gel electrophoresis in the presence of SDS

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular diversity and polymerase gene genotypes of HIV-1 among treatment-naïve Cameroonian subjects with advanced disease

Keywords: HIV-1; Drug resistance; Cameroon; Recombination; RNase H

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Drug-resistant mutation patterns in CRF01_AE cases that failed d4T + 3TC + nevirapine fixed-dosed, combination treatment: Follow-up study from the Lampang cohort

Keywords: CRF01_AE; Polymorphism; Drug resistance; Connection domain; RNase H; GPOvir;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Aminoglycoside modifying enzymes

Keywords: Antibiotic resistance; Aminoglycoside; Aminoglycoside modifying enzyme; Acetyltransferase; Nucleotidyltransferase; Phosphotransferase; Kinase; Antisense; RNase P; RNase H; Bacterial infection

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2010 سفارش ترجمه

Retroviral self-inactivation in the mouse vagina induced by short DNA

Keywords: Lentiviral vector; HIV; RNase H; Microbicide; Virus suicide; Hairpin-loop DNA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

A Single Mutation at Residue 25 Populates the Folding Intermediate of E. coli RNase H and Reveals a Highly Dynamic Partially Folded Ensemble

Keywords: RNase H, ribonuclease H; ANS, 1-anilino-8-naphthalene sulfonic acid; HSQC, heteronuclear single quantum coherenceprotein dynamics; protein folding intermediates; RNase H

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Murine leukemia virus reverse transcriptase: Structural comparison with HIV-1 reverse transcriptase

Keywords: Reverse transcriptase; RNase H; Moloney murine leukemia virus; Reverse transcription; Retrovirus

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2008 سفارش ترجمه

RNase H activity: Structure, specificity, and function in reverse transcription

Keywords: RNase H; Reverse transcriptase; Human immunodeficiency virus, type 1 (HIV-1); Moloney murine leukemia virus (MoMLV); Reverse transcription; Polypurine tract (PPT)

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular beacons for isothermal fluorescence enhancement by the cleavage of RNase HII from Chlamydia pneumoniae

Keywords: RNase H; Molecular beacons; Chlamydia pneumoniae; Isothermal fluorescence enhancement

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه